Modeling of auditory neuropathy spectrum disorders associated with the TEME43 variant reveals impaired gap junction function of iPSC-derived glia-like support cells by Xiaoming Kang, Xiaoming Kang, Lu Ma, Lu Ma, Lu Ma, Jie Wen, Jie Wen, Wei Gong, Wei Gong, Xianlin Liu, Xianlin Liu, Yihan Hu, Yihan Hu, Zhili Feng, Zhili Feng, Qiancheng Jing, Qiancheng Jing, Yuexiang Cai, Yuexiang Cai, Sijun Li, Xinzhang Cai, Kai Yuan, Yong Feng, Yong Feng, Yong Feng, Yong Feng, Yong Feng

“…These mutations could result in developmental defects in GLSs and a diminished capacity for gap junction function, which may be implicated in the auditory deficits observed in ANSD patients. …”
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Development and Validation of the Pediatric Well-Being Picture Scale© Using a Mixed-Methods Research Design by Judith Quaranta, Rosa Darling, Mei-Hsiu Chen, Julia DeMartino, Madison Kozlowski

“…The purpose of our research was to develop the Pediatric Well-Being Picture Scale© (PWBPS©), the first picture-based screening tool for ages 8–11 years, accessible to children regardless of their literacy, language skill, and developmental levels, allowing for quick screening for early referral and intervention. …”
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Evaluating the Effectiveness of Parent Training Pamphlets: An Intervention Study Among Parents at Child Health Checkups by Kazuko Akutsu, Aya Goto, Fareeda Abo-Rass, Hiroyuki Yokoyama

“…Subgroup analyses revealed significant differences in adherence among parents whose children were identified to have developmental concerns at the 1.5-year health checkup and were required to have follow-up checkups, specifically in the “avoid immediate reactions” approach between intervention and control groups. …”
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Cohort profile: Anhui Maternal–Child Health Study in China by Yunxia Cao, Ruoling Chen, Weiju Zhou, Xiaofeng Xu, Xiaoqing Peng, Jiaqian Yin, Chunmei Liang, Ranjit Khutan, Fang-Biao Tao

“…Details of their children’s health are documented through a questionnaire focusing on developmental status and anthropometry measurement.Findings to date Until April 2021, AMCHS had recruited 2042 couples in the study. 111 women withdrew from the study and 19 failed to retrieve oocytes. …”
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Analysis of the 2016 – 2025 fiscal budget of U.S. Centers for Disease Control and Prevention by Nana LIU, Lieyu HUANG, Yuan DANG, Zekai YU, Qianqiu LIU, Yan GUO

“…The budget for "Birth Defects, Developmental Disabilities, Disabilities and Health" remained at a relatively low level with minor fluctuations (US$ 0.100 billion to US$ 0.223 billion). …”
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Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia. by Hildegard Nikki Hall, Hemant Bengani, Robert B Hufnagel, Giuseppe Damante, Morad Ansari, Joseph A Marsh, Graeme R Grimes, Alex von Kriegsheim, David Moore, Lisa McKie, Jamalia Rahmat, Catia Mio, Moira Blyth, Wee Teik Keng, Lily Islam, Meriel McEntargart, Marcel M Mannens, Veronica Van Heyningen, Joe Rainger, Brian P Brooks, David R FitzPatrick

“…We found limited evidence for mutation-specific interactions with MSI2/Musashi-2, an RNA-binding proteins with effects on many different developmental pathways. Given that biallelic loss-of-function variants in MAB21L1 result in a milder eye phenotype we suggest that Arg51-altering monoallelic variants most plausibly perturb eye development via a gain-of-function mechanism.…”
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Children’s emerging concepts of resilience: insights from using body mapping in an East London cohort sample of 7-10-year-old children by Aisling Murray, Dominie Mahala Smith Scott, Milena Nikolajeva, Daniele Porricelli, Francois van Loggerenberg, Dennis Ougrin, Jennifer Y. F. Lau

“…Middle childhood is an understudied developmental stage, with many quantitative measures lacking validation for this age group and not capturing diverse experiences. …”
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Interrelationships between social exclusion, mental health and wellbeing in adolescents: insights from a national Youth Survey by K. Filia, S. M. Teo, N. Brennan, T. Freeburn, D. Baker, V. Browne, A. Watson, J. Menssink, A. Prasad, E. Killackey, P. D. McGorry, S. M. Cotton, C. X. Gao

“…Abstract Aims Adolescence is a critical developmental phase during which young people are vulnerable to the experiences of mental ill-health and social exclusion (consisting of various domains including education and employment, housing, finances and social supports and relationships). …”
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Selective and persistent toxicity of seven insecticides to five egg parasitoids of Spodoptera frugiperda by Hao-Ran Li, Cheng-Yang Li, Peng Dai, Lian-Sheng Zang, Nicolas Desneux, Wei Xu

“…Chlorantraniliprole exhibited exceptional safety for all developmental stages (adult, egg, and pupa) of the five egg parasitoid species. …”
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The relationship between bats and human coronavirus: An exploratory review by Sajal BHATTACHARYA, Shakya SINHA, Rina TILAK, Sugeng Juwono MARDIHUSODO

“…Anthropogenic activities like encroachment of wildlife habitat, deforestation, developmental activities and close encounter with wild animals, cause disturbances in ecosystem functioning. …”
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Maternal nutrition and offspring lung health: sex-specific pathway modulation in fibrosis, metabolism, and immunity by Shuangyi Zhao, Zhimin Chen, Huina Liu, Xinyan Wang, Xiuru Zhang, Huirong Shi

“…Previous studies have demonstrated that maternal dietary habits can affect key developmental pathways in the offsprings, including those related to lung function and disease susceptibility. …”
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POSSIBILITIES OF DIAGNOSIS OF RADIATION INJURIES AND REHABILITATION OF PATIENTS AFTER COMBINED TREATMENT OF MALIGNANT TUMORS OF THE BREAST by A. V. Kondakov, M. E. Borodina, O. V. Andrianov, N. I. Rozhkova

“…In individual cases, to assess the developmental stages of lymphedema using lymphoscintigraphy and MRI.Results. …”
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Identification of methyltransferase and demethylase genes and their expression profiling under biotic and abiotic stress in pigeon pea (Cajanus cajan [L.] Millspaugh) by Priyanka Kumari, Priyanka Kumari, Sougata Bhattacharjee, Sougata Bhattacharjee, K. Venkat Raman, Jyotsana Tilgam, Jyotsana Tilgam, Krishnayan Paul, Krishnayan Paul, Kameshwaran Senthil, Mahi Baaniya, Mahi Baaniya, G. Rama Prashat, Rohini Sreevathsa, Debasis Pattanayak

“…Relative expression analysis of the identified genes in various tissues at different developmental stages revealed the highest level of expression in leaf and the least in root. …”
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Paleoclimatic and paleoenvironmental constraints on organic matter enrichment in the Paleocene strata in the Lishui Sag, East China Sea Shelf Basin by Shiyan Yin, Chuang Lei, Jiaren Ye, Jingfu Wu, Yu Wang, Ying Zhang, Xiaoying Han

“…The Yueguifeng Formation has greater hydrocarbon-generating potential than the Lingfeng and Mingyuefeng formations. Constructing the developmental models of organic-rich mudstones based on the covariation in the paleoclimatic and paleoenvironmental conditions represents a valid method for understanding the hydrocarbon-generating potential of these source rocks.…”
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Management of the Striga epidemics in pearl millet production: a review by Armel Rouamba, Hussein Shimelis, Inoussa Drabo, Kwame Wilson Shamuyarira, Emmanuel Mrema

“…The first section of the review assesses the impact of Striga infestation on pearl millet production, followed by the developmental stages of Striga, Striga infestation and damage management strategies, breeding for Striga resistance and other Striga control methods. …”
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Impact of the Timing of Enzyme Replacement Therapy Initiation and Cognitive Impairment Status on Outcomes for Patients with Mucopolysaccharidosis II (MPS II) in the United States:... by Karen S. Yee, David Alexanderian, Yidie Feng, Xiaowei Ren, Bernd Schweikert, Olulade Ayodele

“…**Results:** In patients initiating ERT before 3 years of age, there was a trend toward lower symptom burden and HRU compared with patients who initiated ERT at an older age. Evaluation of developmental and behavioral signs and symptoms in the full study population showed that communication delay (70.0% of patients), cognitive delay (62.1%), behavioral problems (52.9%), and toileting delay (50.0%) were particularly common; earliest documented signs and symptoms were motor delay (median [range] age at first documentation: 4.2 [0.9-18.7] years) and behavioral problems (4.4 [0.6-13.7] years). …”
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In Vitro Anthelmintic Activity and Phytochemical Screening of Crude Extracts of Three Medicinal Plants against Haemonchus Contortus in Sheep at Haramaya Municipal Abattoir, Eastern... by Hassen Shamil Mumed, Dereje Regassa Nigussie, Kedir Sali Musa, Abdallahi Abdurahman Demissie

“…Hence, the current study revealed that the extracts from three plants have potential anthelmintic effect, and we recommend further study on fractionating each component separately and validating the materials using other parasite developmental stages are warranted.…”
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Development of an m6A-Related lncRNAs Signature Predicts Tumor Stemness and Prognosis for Low-Grade Glioma Patients by Dahua Xu, Peihu Li, Chunrui Zhang, Yutong Shen, Jiale Cai, Qingchen Wei, Meng Cao, Zhizhou Xu, Deng Wu, Hong Wang, Xiaoman Bi, Bo Wang, Kongning Li

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Human Brain Organoid: A Versatile Tool for Modeling Neurodegeneration Diseases and for Drug Screening by Cuili Ma, Hwanwook Seong, Xiaowei Li, Xiao Yu, Shunliang Xu, Yujing Li

“…Undoubtedly, animal models have made a significant contribution to gaining insight into the developmental and pathophysiological understanding of human diseases. …”
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Representing and Quantifying Conformational Changes of Kinases and Phosphatases Using the TSR-Based Algorithm by Tarikul I. Milon, Krishna Rauniyar, Sara Furman, Khairum H. Orthi, Yingchun Wang, Vijay Raghavan, Wu Xu

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