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2781
Predicting Hope in Mothers of Intellectually Disabled Children Through Emotional, Psychological and Spiritual Factors
Published 2024-11-01“…Background and Objectives: Mental retardation is associated with a lack of growth in various physical, mental, developmental, social, and educational dimensions. Many variables, such as emotional adjustment, psychological well-being, and spiritual beliefs are related to the hope of mothers with mentally retarded children. …”
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2782
How can urban expansion and ecological preservation be balanced? A simulation of the spatial dynamics of production-living-ecological spaces in the Huaihe River Eco-Economic Belt
Published 2025-02-01“…This study utilizes a combination of the Future Land Use Simulation (FLUS) model and the Markov model to analyze how various developmental scenarios might influence the spatial dynamics of the Production-Living-Ecological Spaces (PLES) structure. …”
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2783
Retrospective observational cohort study of premature neonates screened for ROP with 7 years of follow-up assessing the visual outcomes and adequacy of preschool visual screening
Published 2024-12-01“…Background Very premature infants screened for retinopathy of prematurity (ROP) that do not develop ROP still experience serious visual developmental challenges, and while it is recommended that all children in the UK are offered preschool visual screening, we aimed to explore whether this vulnerable group requires dedicated follow-up.Methods We performed a real-world retrospective observational cohort study of children previously screened for ROP in NHS Greater Glasgow and Clyde (Scotland) between 2013 and 2015. …”
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2784
Novel nonsense mutation in gene CHRNA2 identified by whole-genome sequencing in infant with epilepsy disorder: A case report
Published 2025-01-01“…It impacts people of all genders and ages, but evidence suggests a higher incidence rate in children and the elderly.Given that childhood epilepsy has the risk of causing developmental epileptic encephalopathy, which is associated with intellectual, behavioral, and/or motor disabilities, proper assessment of children with new-onset epilepsy at an early stage is essential to prevent threats affecting neurodevelopmental processes. …”
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2785
Fetal Cartilage Progenitor Cells in the Repair of Osteochondral Defects
Published 2025-03-01“…IZN or ANL cells exhibited some potential to recapitulate developmental features during cartilage repair. However, identifying regulatory determinants of IZN and ANL-derived overgrowths is necessary. …”
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2786
Chinese cabbage orphan gene BR3 confers bolting resistance to Arabidopsis through the gibberellin pathway
Published 2025-01-01“…The expression of BR3 was developmentally regulated and occurred during the seedling and flowering stages. …”
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2787
Endometriosis does not impact aneuploidy rates of products of conception in IVF population
Published 2025-01-01“…Abstract It has been debated whether endometriosis (EMS) adversely affects oocyte quality, potentially leading to a higher incidence of genetically unbalanced embryos or other egg factors that affect the developmental potential. In this study, we explored the effects of endometriosis on risk of chromosomally aberrant in miscarried products of conception (POC) after assisted reproductive treatment (ART), including fresh and frozen cycles. …”
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2788
Chronic Rapamycin Prevents Electrophysiological and Morphological Alterations Produced by Conditional Pten Deletion in Mouse Cortex
Published 2025-01-01“…Abnormalities in the mammalian target of the rapamycin (mTOR) pathway have been implicated in numerous developmental brain disorders. While the molecular and histological abnormalities have been described, less is known about alterations in membrane and synaptic excitability with chronic changes in the mTOR pathway. …”
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2789
Role of Endogenous Hormones on Seed Hardness in Pomegranate Fruit Development
Published 2025-01-01“…We compared changes in hormones during the development of soft- and hard-seeded varieties in order to identify key hormones and developmental stages that affect seed lignin synthesis and accumulation. …”
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2790
Novel Compound Heterozygous BBS2 and Homozygous MKKS Variants Detected in Chinese Families with Bardet–Biedl Syndrome
Published 2021-01-01“…Bardet–Biedl syndrome (BBS) is a rare multisystem developmental disorder. In this study, we report the genetic causes and clinical manifestations in two Chinese families with BBS. …”
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2791
Uterus didelphys: the first case report on molecular profiling of endometrial tissue from both uterine cavities
Published 2025-01-01“…This anomaly arises due to partial or incomplete merging of the Müllerian ducts during the developmental stages in the womb. Accounting for uterine malformations, a didelphic uterus is a relatively rare condition, affecting approximately 0.5–2% of the population and is considered one of the more uncommon types of uterine abnormalities. …”
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2792
Parental Evaluation of a Responsive Parenting Program for Infants with Hearing Loss
Published 2025-01-01“…Their infants (<i>N</i> = 45) had moderate to complete hearing loss, they were aged 2–20 months, and 40% of them had an additional disease, disorder, and/or developmental delay. Results: Parents reported high levels of satisfaction with the content, didactics, setting, and individual benefits of the intervention, and a high recommendation rate (92%). …”
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2793
Double-blind, randomised, placebo-controlled trial to evaluate the effectiveness of late gestation oral melatonin supplementation in reducing induction of labour rates in nulliparo...
Published 2025-01-01“…Secondary endpoints will include the following: interval between administration of trial medication and birth; a range of maternal and neonatal outcomes, including birth outcomes; breastfeeding on discharge, at 10 days and at 2 months; maternal satisfaction; child developmental outcomes at 2 months of age; and cost-effectiveness of melatonin compared with standard care. …”
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2794
Examining tolerability, safety, and blinding in 1032 transcranial electrical stimulation sessions for children and adolescents with neuropsychiatric and neurodevelopmental disorder...
Published 2025-02-01“…., attention deficit and hyperactivity disorder, developmental dyscalculia) conditions. It compared adverse events (AEs) occurrence between active and sham transcranial electrical stimulation (tES) conditions (i.e., 528 active vs. 504 sham sessions) as well as tDCS and tRNS (i.e., 772 tDCS sessions vs. 260 tRNS sessions), while considering demographic and emotional-behavioural factors. …”
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2795
Towards PErsonalised PRognosis for children with traumatic brain injury: the PEPR study protocol
Published 2022-06-01“…Therefore, this study aims to develop prognostic models for the individual outcome of children with TBI in a range of important developmental domains. In addition, the potential added value of advanced neuroimaging data and the use of machine learning algorithms in the development of prognostic models will be assessed.Methods and analysis 210 children aged 4–18 years diagnosed with mild-to-severe TBI will be prospectively recruited from a research network of Dutch hospitals. …”
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2796
Clinical Features and Genetic Characteristics of XLID Patients With KDM5C Gene Mutations: Insights on Phenotype–Genotype Correlations From 175 Previous Cases and Identification of...
Published 2025-01-01“…ABSTRACT Background X‐linked intellectual disability (XLID) is a genetically heterogeneous disorder that results in cognitive impairment and developmental delays. Mutations in the KDM5C gene have been identified as a causative factor in XLID. …”
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2797
Damage symptoms, development, and reproductive performance of the fall armyworm, Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae) on fodder maize and cob
Published 2023-03-01“…The results of this study could play a significant role in predicting the damage and reproductive performance of FAW in maize fields during their developmental growth, which will further help in developing effective integrated management techniques against this pest.…”
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2798
Glia control experience-dependent plasticity in an olfactory critical period
Published 2025-01-01“…Sensory experience during developmental critical periods has lifelong consequences for circuit function and behavior, but the molecular and cellular mechanisms through which experience causes these changes are not well understood. …”
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2799
Research priorities for preterm lung health research across the lifespan: a community priority setting partnership
Published 2025-02-01“…Participants identified the following top 10: (1) lifelong impacts; (2) interventions, treatments or supports; (3) ongoing lung health follow-up; (4) diagnostic tools, resources and education for primary healthcare providers; (5) resources to inform and empower families; (6) relationship to physical health and developmental issues; (7) preventing and/or treating lung infections; (8) additional supports, resources and research for minority groups; (9) impact on mental well-being; and (10) likelihood of asthma diagnosis.Conclusion Priorities identified through the PSP will be invaluable in informing future research into prematurity-associated lung disease.…”
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2800
Effect of cytoplasmic male sterility type on chlorophyll content in leaves of grain sorghum hybrids
Published 2015-12-01“…Pishchevoye 35 (P35) and Mercury), we focused our attention on the effects of A3, A4, 9E, and M35-1A cytoplasms on chlorophyll content at different developmental stages of sorghum plants. It was found that hybrids with different types of male-sterile cytoplasm differed in chlorophyll content, and the genotypes of the CMS line and the pollen parent influenced the manifestation of cytoplasmic differences. …”
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