Transitioning from paper-based to web-based testing in an ESP course at HEI by Jovana Jović, Marija Stojanov

“…Such testing is not only time-consuming and inefficient owing to the lengthy test development, grading, and reviewing processes, but also stressful for teachers due to the possible grading mistakes, miscalculation of points, illegible students’ handwriting, etc. …”
Get full text

DOSE-ESCALATED EXTERNAL BEAM RADIOTHERAPY DURING HORMONO-RADIOTHERAPY FOR PROSTATE CANCER by Yu. V. Gumenetskaya, Yu. S. Mardynskiy, I. A. Gulidov, O. B. Karyakin, V. S. Chaykov

“…Of 11 (7.1 %) patients who had rectum complications, 8 (5.1 %) patients developed grade I complications, and 3 (1.9 %) patients developed grade II complications. …”
Get full text

Impaired liver function: effect on paclitaxel toxicity, dose modifications and overall survival by Marieke Schmidt, Robin Vernooij, Merel van Nuland, Erin Smeijsters, Lot Devriese, Nadia Haj Mohammad, Thom Hermens, Julian Stammers, Christina Swart, Toine Egberts, Saskia Haitjema, Laureen Lammers

“…Breast cancer patients who were receiving advanced treatment and had mildly impaired liver function (ASAT ≤ 2x ULN, bilirubin ≤ ULN) had an increased risk of developing grade 3/4 neutropenia (HR = 4.39, 95% CI 1.20-16.02; p = 0.03). …”
Get full text

Marketing monitoring of biotechnological internet resources and internet market of ecology related biotechnological developments. by E. A. Demcheva, M. V. Tsarikovskaya, E. I. Khabarova, V. B. Lukmanov

“…The development grade of biotechnological branch is varies significantly according to every different branch direction. …”
Get full text

Dose escalation (81 Gy) with image-guided radiation therapy and volumetric-modulated arc therapy for localized prostate cancer: A retrospective preliminary result by Sheng-Yao Huang, Chen-Ta Wu, Dai-Wei Liu, Tzu-Hwei Wang, Yen-Hsiang Liao, Yi-Wei Chen, Wen-Lin Hsu

“…Three (5.6%) patients developed Grade II acute gastrointestinal (GI) toxicity. …”
Get full text

HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR PAEDIATRIC PATIENTS WITH X-LINKED LYMPHOPROLIFERATIVE SYNDROME by Yuan Sun

“…STR-PCR analysis on the peripheral blood cells showed complete donor origins. Four cases developed Grade I acute graft versus host disease (aGVHD), one developed Grade III aGVHD (intestinal tract), and two cases had limited chronic GVHD. …”
Get full text

Evaluation of program activities to improve access to the city transport system for people with limited mobility by K. E. Safronov, S. M. Mochalin

“…The unavailability of the transport system reduces the mobility and leads to discrimination on the basis of disability. Developed grade system of accessibility is directed to assess the effectiveness of program activities. …”
Get full text

Intestinal Perforation due to Neutropenic Enterocolitis in a Patient Treated with Bevacizumab for Ovarian Cancer by Akinori Sasaki, Kenichi Harano, Takahiro Kogawa, Nobuaki Matsubara, Yoichi Naito, Ako Hosono, Hirofumi Mukai, Takayuki Yoshino, Toru Mukohara

“…A 66-year-old woman diagnosed with metastatic ovarian cancer received combination chemotherapy with carboplatin, gemcitabine, and bevacizumab. On day 14, she developed grade 4 pancytopenia and febrile neutropenia, which resulted in neutropenic enterocolitis and intestinal perforation. …”
Get full text

Treatment of IL-10RA deficiency of pediatric patients with very early onset inflammatory bowel disease by allogeneic haematopoietic stem cell transplantation by Yafeng Wang, Dandan Liu, Haili Gao, Wei Liu, Yanna Mao

“…Hematopoietic reconstruction was performed on seven children with VEO-IBD combined with IL-10RA deficiency. Four patients developed grade I-II GVHD, while three patients developed grade III-IV GVHD after undergoing allo-HSCT. …”
Get full text

Single domain wall propagation in Co-rich magnetic microwires with graded magnetic anisotropy by P. Corte-León, V. Zhukova, J. M. Blanco, J. Gonzalez, A. Zhukov

“…We observed that the annealing of Co-rich microwire at variable temperature allows to develop graded magnetic anisotropy. In such microwires, annealed with a temperature gradient, gradual variation of the hysteresis loops along the microwire length is observed. …”
Get full text

Predictive value of intra-hepatectomy ICGR15 of the remnant liver for post-hepatectomy liver failure in hemi-hepatectomy: a prospective study by Tianyi Liang, Yongfei He, Shutian Mo, Yuan Liao, Ketuan Huang, Qiang Gao, Xiaoqiang Shen, Chengkun Yang, Xiwen Liao, Wei Qin, Guangzhi Zhu, Hao Su, Xinping Ye, Chuangye Han, Tao Peng

“…An intra-hepatectomy ICGR15 threshold of 19.8% might effectively identify patients at high risk of developing grade B/C PHLF and severe post-hepatectomy complications, helping surgeons’ final decision-making on the table.…”
Get full text

Phase II Evaluation of Ultra-Hypofractionated Postoperative Radiation Therapy for Breast Cancer: Toxicity and Efficacy in a Single-Center Nonrandomized Prospective Study by Marcel Fang, Vinicius de Carvalho Gico, Lucas Casimiro, Bruno Takatsu, Elson Santos Neto, Rossana Veronica Mendoza Lopez, Gustavo Vilela Costa Pinto, Gustavo Nader Marta

“…Late toxicity included 1.7% (n = 1) of patients developing grade 3 fibrosis and 1.7% (n = 1) developing grade 3 pneumonitis. …”
Get full text

Efficacy of the Radiotherapy on Darier’s Disease: An Indirect Evidence by Ala Podgornii, Patrizia Ciammella, Dafne Ramundo, Cinzia Iotti

“…During the radiation, she developed grade 1 to 2 dermatitis in the irradiated area. …”
Get full text

A neural network regression model for predicting student learning success based on prior achievements by Dorrer Mikhail

“…More than 70% of the developed grade prediction models demonstrated a coefficient of determination greater than 0.7, with the RMSE of predicted grades from actual values being less than one point on a five-point scale. …”
Get full text

Immunotherapy in Advanced Cutaneous Melanoma: From the Optimal Treatment Duration to the Impact on Survival in Case of Early Discontinuation Due to Immune-Related Adverse Events by Giacomo Triggiano, Gaetano Pezzicoli, Marco Tucci

“…Another point of interest is the impact of the early discontinuation of ICIs on the maintenance of response in terms of survival in patients developing grade 3–4 adverse events that mostly occur in those receiving the combo-IT. …”
Get full text

Case Report: Immune-mediated acute liver failure induced by tislelizumab in a patient with advanced cervical cancer by Chaoxia Liu, Xinchun Li, Yuping Deng

“…After three cycles of concurrent chemoradiotherapy and Tislelizumab, she developed grade 4 immune-mediated hepatitis and ALF following a fourth Tislelizumab dose, marked by severe transaminitis (AST 5329 U/L, ALT 2384 U/L), coagulopathy (INR 5.85), hyperbilirubinemia (TBIL 56.99 IU/L), and hepatic encephalopathy. …”
Get full text

Broken double-J stent in a 40-year-old male with a history of ureteral calculus by Nirja Thaker, MBBS, Rajasbala Dhande, MD, PHD, P.H. Parihar, MD, PHD, Bhargav Patel, MS

“…Despite the absence of infection or substantial pyuria, the patient developed grade 2 hydronephrosis. The stent fragments were effectively removed via ureteroscopy. …”
Get full text

Stepwise diet management in pediatric gastrointestinal graft versus host disease by Nevra Koç, Mehmet Gündüz, M Fatih Azık, Betül Tavil, Dilek Gürlek-Gökçebay, Eda Özaydın, Bahattin Tunç, Duygu Uçkan

“…A total of 105 patients underwent SCT and seven patients developed grade III-IV acute GI-GVHD. Total parenteral nutrition (TPN) was initiated to all patients after the diagnosis of GI-GVHD and minimal enteral nutrition (1-2 ml/kg/day standard pediatric enteral formula/special meat soup) was given to the patients. …”
Get full text

Blockade of acute grade IV skin and eye graft-versus-host disease by anti-interleukin-2 receptor monoclonal antibody in genoidentical bone marrow transplantation setting by H Ozşahin, P Tuchschmid, R Lauener, K Waldvogel, D Nadal, R A Seger

“… A six-year-old boy with homozygous beta-thalassemia in the favorable class 1 risk group received a bone marrow transplant, from his histocompatible sister. He developed grade IV skin and eye graft-versus-host disease (GVHD) following varicella zoster reactivation. …”
Get full text

Review of outcomes in a veteran treated with lurbinectedin long-term for extensive-stage small cell lung cancer: A case report by Jana Sawyer, Megan Banaszynski, Brian Do, Jesse Cobell

“…Here, we present a case report of a patient who was treated with lurbinectedin for approximately 2 years and maintained stable disease while receiving a reduced dose. The patient developed grade 3 anemia which resolved following a dose reduction of lurbinectedin, allowing for mitigation of toxicity while maintaining the clinical efficacy of the drug. …”
Get full text