Fas Ligand DNA Enhances a Vaccination Effect by Coadministered DNA Encoding a Tumor Antigen through Augmenting Production of Antibody against the Tumor Antigen by Boya Zhong, Guangyu Ma, Ayako Sato, Osamu Shimozato, Hongdan Liu, Quanhai Li, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa

“…Growth of β-gal-positive Colon 26 tumors was retarded in the syngeneic mice immunized with β-gal and FasL DNA compared with those vaccinated with β-gal or FasL DNA. We did not detect increased numbers of β-gal-specific CD8+ T cells in lymph node of mice that received combination of β-gal and FasL DNA, but amounts of anti-β-gal antibody increased with the combination but not with β-gal or FasL DNA injection alone. …”
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ASKAP Observations of the Radio Shell in the Composite Supernova Remnant G310.6-1.6 by Wenhui Jing, Jennifer L. West, Xiaohui Sun, Wasim Raja, Xianghua Li, Lingxiao Dang, Ping Zhou, Miroslav D. Filipović, Andrew M. Hopkins, Roland Kothes, Sanja Lazarević, Denis Leahy, Emil Lenc, Yik Ki Ma, Cameron L. Van Eck

“…We report the observations of the radio shell of the supernova remnant (SNR) G310.6–1.6 at 943 MHz from the Evolutionary Map of the Universe (EMU) and the Polarization Sky Survey of the Universe’s Magnetism (POSSUM) surveys by using the Australian Square Kilometre Array Pathfinder (ASKAP). We detect polarized emission from the central pulsar wind nebula (PWN) with rotation measures varying from –696 rad m ^−2 to –601 rad m ^−2 . …”
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Staphylococcus aureus carriage is associated with microbiome composition in the nares and oropharynx, not the hand, of monozygotic twins by Mark R. Dalman, W. Brian Simison, Danny Nielsen, Sabana Bhatta, Noor Ramahi, Clair Yee, Dipendra Thapaliya, Jhalka Kadariya, Shanice Cheatham, Hailee Olson, Tara C. Smith

“…The prevalence of S. aureus was highest in the oropharynx followed by nares and hand with concordance between twin pairs highest in the nares, followed by oropharynx. The detection of S. aureus was statistically correlated with differences in microbiome composition across sites, as indicated by beta diversity and DESeq2 analyses. …”
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Resolving the electronic ground state of La3Ni2O7-δ films by Xiaolin Ren, Ronny Sutarto, Xianxin Wu, Jianfeng Zhang, Hai Huang, Tao Xiang, Jiangping Hu, Riccardo Comin, Xingjiang Zhou, Zhihai Zhu

“…Additionally, in La3Ni2O7-δ films, we detect a superlattice reflection (1/4, 1/4, L) at the Ni L absorption edge using resonant X-ray scattering measurements. …”
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3D Semantic VSLAM of Indoor Environment Based on Mask Scoring RCNN by Chongben Tao, Yufeng Jin, Feng Cao, Zufeng Zhang, Chunguang Li, Hanwen Gao

“…In order to achieve object detection and semantic segmentation for both static objects and dynamic objects in indoor environments and then construct dense 3D semantic map with VSLAM algorithm, a Mask Scoring RCNN is used to adjust its structure partially, where a TUM RGB-D SLAM dataset for transfer learning is employed. …”
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Determination of Residual Nonsteroidal Anti-Inflammatory Drugs in Aqueous Sample Using Magnetic Nanoparticles Modified with Cetyltrimethylammonium Bromide by High Performance Liqui... by Malihe Khoeini Sharifabadi, Mohammad Saber-Tehrani, Syed Waqif Husain, Ali Mehdinia, Parviz Aberoomand-Azar

“…The calibration curves obtained for studied drugs show reasonable linearity (R2>0.99) and the limit of detection (LODs) ranged between 2 and 7 ng/mL. Finally, the proposed method has been effectively employed in extraction and determination of the drugs in biological and environmental samples.…”
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The Silent Threat of Human Metapneumovirus: Clinical Challenges and Diagnostic Insights from a Severe Pneumonia Case by Rubens Carmo Costa-Filho, Felipe Saddy, João Luiz Ferreira Costa, Leandro Reis Tavares, Hugo Caire Castro Faria Neto

“…Background: Human metapneumovirus (hMPV) is a respiratory pathogen that has gained increasing recognition due to advancements in molecular diagnostic tools, which have improved its detection and characterization. While severe disease manifestations are traditionally associated with pediatric, elderly, or immunocompromised patients, hMPV-related pneumonia in immunocompetent adults remains underexplored. …”
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Putative Identification of 47 Compounds from Jieyu Anshen Granule and Proposal of Pharmacopeia Quality‐Assessment Strategy Using TCM‐Specific Library with UHPLC‐Q‐Exactive‐Orbitrap... by Xican Li, Jingyuan Zeng, Rongxin Cai, Chunhou Li, Xiaoshan Chen, Ban Chen, Xiaojun Zhao, Sunbal Khan

“…This strategy enables the detection of adulteration in relation to Zhizi, Chaihu, Zhigancao, Danggui, and Yuanzhi in Jieyu Anshen Granule. …”
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Neonatal Screening for Congenital Hypothyroidism: A Study Conducted in a Tertiary Care Hospital of Gujarat by Shubhangi Rathod, Ramesh Pradhan, Rosy Lekharu, Jaydip Vala, Mehak Kulshrestha

“…Aims and objectives: Aims: Assessment of possible methods for screening/early detection of CH in neonates. Primary objective: Compare and correlate cord blood (CB) thyroid stimulating hormone (TSH) with heel prick TSH, as a marker of CH. …”
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Comparative Analysis of AES, Blowfish, Twofish, Salsa20, and ChaCha20 for Image Encryption by Rebwar Khalid Muhammed, Ribwar Rashid Aziz, Alla Ahmad Hassan, Aso Mohammed Aladdin, Shaida Jumaah Saydah, Tarik Ahmed Rashid, Bryar Ahmad Hassan

“…The recognition of threats and attacks meant for knowledge and safety on the internet is growing harder to detect. Since cybersecurity guar-antees the privacy and security of data sent via the Internet, it is essential, while also providing protection against malicious attacks. …”
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Study protocol for the development and pilot-testing of a Self-assessment tool for the implementation of the European Standards of Care for Newborn Health (ESCNH) by James Webbe, Helmut Hummler, Luc J I Zimmermann, Ylva Thernström Blomqvist, Nicholas Lack, Dietmar Schlembach, Julia Hoffmann, Silke Mader, Eleni Vavouraki, Sarah Lehmann, Gina Ancora, Esther Schouten, Ilaria Simonelli, Isabel Geiger

“…We aim to develop a digital self-assessment tool for HCPs to detect the local level of ESCNH fulfilment and identify areas in need of improvement, and thus provide recommendations for action.Methods and analysis The self-assessment tool will have the form of a digital questionnaire with condensed ESCNH content. …”
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SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection by Richard C. Crist, Samar N. Chehimi, Saurabh S. Divakaran, Michael J. Montague, Sébastien Tremblay, Noah Snyder-Mackler, Martin O. Bohlen, Kenneth L. Chiou, Trish M. Zintel, Cayo Biobank Research Unit, Michael L. Platt, Halvor Juul, Guido Silvestri, Matthew R. Hayes, Dennis L. Kolson, Benjamin C. Reiner

“…Differential expression identified alterations in cellular subtype gene expression that persisted over the 20-day time course and short-lived differences only detected at 10-days post-SIV infection. In silico predicted regulatory mechanisms and dysregulated neural signaling pathways are presented. …”
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Comparison of Immunomodulation Properties of Porcine Mesenchymal Stromal/Stem Cells Derived from the Bone Marrow, Adipose Tissue, and Dermal Skin Tissue by Sun-A Ock, Raghavendra Baregundi Subbarao, Yeon-Mi Lee, Jeong-Hyeon Lee, Ryoung-Hoon Jeon, Sung-Lim Lee, Ji Kwon Park, Sun-Chul Hwang, Gyu-Jin Rho

“…Except for the lipoprotein gene, there were no marked changes in osteogenesis- and adipogenesis-related genes following in vitro differentiation; however, the histological marker analysis revealed that adipose MSCs could be differentiated into both adipose and bone tissue. TGFβ and IL10 were detected in adipose MSCs and bone marrow MSCs, respectively. …”
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Phosphatidylserine on sperm head interact with Annexin A5 on oviduct luminal cilia to form a sperm reservoir in pigs by Lorraine Schmaltz, Elie Barakat, Renaud Fleurot, Rustem Uzbekov, Karine Reynaud, Ludivine Laffont, Guillaume Tsikis, Isabelle Mérour, Pascal Mermillod, Marie Saint-Dizier

“…Our objective was to explore the role of annexin A5 (ANXA5), a protein that binds with high affinity to phosphatidylserine (PS), in the formation of the sperm reservoir in pigs.Phosphatidylserine was detected on the head of approximately 10 % of boar sperm at ejaculation. …”
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Serine/threonine protein kinase mediates rifampicin resistance in Brucella melitensis through interacting with ribosomal protein RpsD and affecting antioxidant capacity by Yaqin Yuan, Wenqing Ning, Junjie Chen, Jiquan Li, Tianqi Xue, Cuihong An, Lingling Mao, Guangzhi Zhang, Shizhong Zhou, Jiabo Ding, Xiaowen Yang, Jianqiang Ye

“…Recently, an increasing number of rifampicin-resistant Brucella strains have been isolated worldwide without detectable mutations in known antibiotic resistance genes. …”
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Regulation of Murine Ovarian Epithelial Carcinoma by Vaccination against the Cytoplasmic Domain of Anti-Müllerian Hormone Receptor II by Cagri Sakalar, Suparna Mazumder, Justin M. Johnson, Cengiz Z. Altuntas, Ritika Jaini, Robert Aguilar, Sathyamangla V. Naga Prasad, Denise C. Connolly, Vincent K. Tuohy

“…We found that AMHR2-CD immunization of C57BL/6 females induced a prominent antigen-specific proinflammatory CD4+ T cell response that resulted in a mild transient autoimmune oophoritis that resolved rapidly with no detectable lingering adverse effects on ovarian function. …”
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miRNA Expression Profile and Effect of Wenxin Granule in Rats with Ligation-Induced Myocardial Infarction by Aiming Wu, Lixia Lou, Jianying Zhai, Dongmei Zhang, Limin Chai, Bo Nie, Haiyan Zhu, Yonghong Gao, Hongcai Shang, Mingjing Zhao

“…The expressions of miR-1, miR-133, Cx43, and Cx45 were detected by quantitative real-time PCR. It was found that 35 differentially expressed miRNAs and 23 predicted pathways, including miR-1, miR-133, and gap junction pathway, are involved in the pathogenesis of MI. …”
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UHPLC-UV method validation for simultaneous quantification of vitexin and isovitexin from Santalum album L. leaves by Thi Kim Phung Phan, Minh Quan Le, Kien Duc Ngo

“…The quantification procedure was performed on a Hypersil GOLD aQ Column (3 μm; 150 × 2.1 mm) at 35°C, with a mobile phase of acetonitrile (A) and and water with 0.1% formic acid (B), a flow rate of 0.3 mL/min, a detection wavelength of 336 nm, and an injection volume of 3 µL. …”
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Review on Synthesis Method, Classification and AdsorptionSeparation and Sensing Application of Metal-Organic Frameworks (MOFs) Based Composites by Aklilu Melese, Kenaegzer Mulate, Abdu Hussen, Afework Hailekiros, Walelign Wubet

“…Because of these properties, MOFs composites can be used for a wide range of applications, including, sensing toxic chemicals, drugs, gases, and trace metals, components of foods and many more and also for detection of different materials. This is a rapidly developing interdisciplinary research area therefore to present the current situation of the field; this article has covered recent achievements as well as new avenues to investigate the future scope and uses of MOFs composites/hybride.…”
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Short-term growth, movement and response of European eel Anguilla anguilla to re-meandering of a small English chalk stream by Champkin James D., Bašić Tea, Haubrock Phillip J., Balzani Paride, Sayer Carl D., George Laura K., Godard Michael J., Vilizzi Lorenzo, Copp Gordon H.

“…Despite re-meandering work increasing habitat heterogeneity in the restoration reach relative to the control reach, no change in European eel density or size structure was detected across treatments and time. While length and weight increased in the downstream control reach over the study period, density declined. …”
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