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17721
Brain-Specific SNAP-25 Deletion Leads to Elevated Extracellular Glutamate Level and Schizophrenia-Like Behavior in Mice
Published 2017-01-01“…A significantly elevated extracellular glutamate level was detected in the cerebral cortex of the mouse model. …”
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17722
A Survey of Cassini Images of Spokes in Saturn’s Rings: Unusual Spoke Types and Seasonal Trends
Published 2025-01-01“…These statistics demonstrate that while spokes can be detected over a wide range of solar elevation angles, spoke activity increases dramatically when the Sun is within 10° of the ring plane.…”
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17723
Macrocytic anemia, kidney dysfunction, and mortality in general population: Japan specific health checkup study
Published 2024-12-01“…Macrocytic anemia was detected in 2.3% of participants. The prevalence of normocytic and macrocytic anemia increased with advancing CKD stage. …”
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17724
Differential regulation of apoptosis-related genes during long-term culture and differentiation of canine adipose-derived stem cells - a functional bioinformatical analysis
Published 2025-01-01“…A total of 17793 genes were detected and GO enrichment analysis was performed on the differentially expressed genes to identify significantly up- and downregulated Biological Process (BP) GO terms across each comparison.ResultsThe upregulation of apoptosis-regulating genes and genes related to circulatory system development suggest an induction of these processes, while the downregulation of neurogenesis and gliogenesis genes points to reciprocal regulation during osteogenic differentiation of canine ADSCs.DiscussionThese findings underscore the potential of ADSCs in bone regeneration and offer valuable insights for advancing tissue engineering, however further studies, including proteomic analyses, are needed to confirm these patterns and their biological significance.…”
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17725
The Serum S100B Level as a Biomarker of Enteroglial Activation in Patients with Ulcerative Colitis
Published 2014-01-01“…Results. GFAP was not detected in the serum of either UC patients or controls (P>0.05). …”
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17726
Enhancing immunotherapy efficacy in colorectal cancer: targeting the FGR-AKT-SP1-DKK1 axis with DCC-2036 (Rebastinib)
Published 2025-01-01“…Through comprehensive multi-omics investigations, significant shifts in both gene and protein expression profiles were detected, notably a marked decrease in DKK1 levels. …”
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17727
Design and experimental research of pipeline stress measurement system based on alternating current field
Published 2023-10-01“…The optimal excitation direction of the probe is perpendicular to the stress, and the designed portable ACSM based pipeline stress measurement system has been verified to be capable of detecting the stress distortion area of the pipeline. …”
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17728
Evaluation of neutralizing antibody titers against SARS-CoV-2 JN.1 omicron subvariant during pregnancy - A case series study
Published 2025-01-01“…No significant difference in NAb titers was found between symptomatic and asymptomatic women. NAbs were detected in cord blood, especially when infection or vaccination occurred close to delivery, indicating passive immunity transfer to the newborn. …”
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17729
Investigating the Temporal and Spatial Characteristics of Lower Atmospheric Ducts in the Arctic via Long-Term Numerical Simulations
Published 2024-12-01“…Regarding the difference between surface ducts and elevated ducts, a higher frequency of surface ducts was detected in the Arctic region. The height and thickness of surface ducts were generally lower than those of elevated ducts, but the strength of surface ducts was slightly greater. …”
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17730
HPV Infection in Esophageal Squamous Cell Carcinoma and Its Relationship to the Prognosis of Patients in Northern China
Published 2014-01-01“…The 5-year overall survival (OS) and progression-free survival were calculated in relation to these markers and the Cox proportional hazards model was used to determine the hazard ratio (HR) of variables in univariate and multivariate analysis. Results. HPV was detected in 27.6% (29) of the 105 patients with ESCC, and all positive cases were HPV-16. …”
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17731
Feasibility Study of an Alcohol-Based Liquid Scintillation Detector and Its Application
Published 2021-01-01“…A possibility of using alcohol as a new detection solution in a particle detector is described. …”
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17732
Clinical trial to compare safety and tolerability between intravenous infusion and bolus intravenous injection of ApTOLL in healthy volunteers
Published 2025-03-01“…Maximum concentration was detected at the end of the infusion/injection, and mean half-life was 9.5 h for both routes of administration. …”
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17733
Effects of pits of different ages on ethyl acetate and its metabolism-related microorganisms during strong-flavor Baijiu fermentation
Published 2025-01-01“…A total of 690 bacterial genera and 155 fungal genera were detected. The microbial composition of ZPs (fermented grains) from 100 years pit was the most abundant at the genus level. …”
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17734
Determination of Polyphenol Components of Korean Prostrate Spurge (Euphorbia supina) by Using Liquid Chromatography—Tandem Mass Spectrometry: Overall Contribution to Antioxidant Ac...
Published 2014-01-01“…Correlation coefficients (r2) were >0.9907. The limit of detection and limit of quantification of the method were >0.028 mg/L and 0.094 mg/L, respectively. …”
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17735
Invasion of pancreatic ductal epithelial cells by Enterococcus faecalis is mediated by fibronectin and enterococcal fibronectin-binding protein A
Published 2025-01-01“…Abstract The poor prognosis of pancreatic cancer is often attributed to difficulties of early detection due to a lack of appropriate risk factors. …”
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17736
An NR2B-Dependent Decrease in the Expression of trkB Receptors Precedes the Disappearance of Dopaminergic Cells in Substantia Nigra in a Rat Model of Presymptomatic Parkinson's Dis...
Published 2012-01-01“…At this time point, no change in the number of tyrosine hydroxylase (TH) immunoreactive (TH-IR) cells is detected, although a decrease is evident 14 days after neurotoxin injection. …”
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17737
Age and Gender: Affecting the Positive Rates of Serum PAB and ANCA in Patients with Inflammatory Bowel Disease
Published 2021-01-01“…The serum levels of ANCA IgG and IgA were potentiated in old female patients, while serum PAB IgG was easy to be detected in the young male patients with IBD.…”
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17738
Alarmins and their pivotal role in the pathogenesis of spontaneous abortion: insights for therapeutic intervention
Published 2024-12-01“…The purpose of this review is to explore the role of alarmins in SA, and provide important references for early detection of abortion risk, revealing the disease mechanism, developing new therapies and improving the prognosis of patients.…”
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17739
FHL1 as a prognostic biomarker and therapeutic target in acute promyelocytic leukaemia
Published 2025-01-01“…Cell Counting Kit-8 and flow cytometry were used to detect the effect of high or low expression of FHL1 on cell viability and apoptosis under the influence of cytarabine and daunorubicin. …”
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17740
Spectroscopic Confirmation of a Massive Protocluster with Two Substructures at z ≃ 3.1
Published 2025-01-01“…We find that both of these have galaxy overdensities of near-infrared-detected galaxies of δ _gal,obs = 6−9 within corrected volumes of (6−7) × 10 ^3 cMpc ^3 . …”
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