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17701
Identification of p53 and Its Isoforms in Human Breast Carcinoma Cells
Published 2014-01-01“…These observations support the view that the nucleolus is involved directly in the mediation of p53 function or indirectly by the control of the localization of p53 interplayers. p53 expressed in the nuclear fraction of breast cancer cells revealed a wide spectrum of isoforms. p53 isoforms ΔNp53 (47 kDa) and Δ133p53β (35 kDa), known as dominant-negative repressors of p53 function, were detected as the most predominant variants in nuclei of invasive breast carcinoma cells. …”
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17702
Explainable attention based breast tumor segmentation using a combination of UNet, ResNet, DenseNet, and EfficientNet models
Published 2025-01-01“…Dice Loss maximized the overlap between predicted and actual segmentation masks, leading to more precise boundary delineation, while BCE Loss achieved higher recall, improving the detection of tumor areas. Grad-CAM visualizations further demonstrated that attention-based models enhanced interpretability by accurately highlighting tumor areas. …”
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17703
Autoantibodies Targeting AT1 Receptor from Patients with Acute Coronary Syndrome Upregulate Proinflammatory Cytokines Expression in Endothelial Cells Involving NF-κB Pathway
Published 2014-01-01“…Interleukin-6 (IL-6), vascular cell adhesion molecule-1 (VCAM-1), and monocyte chemotactic protein-1 (MCP-1) expression were improved at both mRNA and protein levels in HEC, while NF-κB in the DNA level was improved detected by electrophoretic mobility shift assays (EMSA). …”
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17704
The genomic copy number determination of improved Cre in transgenic mice using standards derived from megaprimer PCR constructed tandem repeats
Published 2024-12-01“…Multiple copies of iCre were detected in founder mice. After several passages, the copy number of iCre gradually decreased to a single copy, which was consistent with theoretical expectation. …”
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17705
The “Gender Factor” in Wearing-Off among Patients with Parkinson’s Disease: A Post Hoc Analysis of DEEP Study
Published 2015-01-01“…Background. The early detection of wearing-off in Parkinson disease (DEEP) observational study demonstrated that women with Parkinson’s disease (PD) carry an increased risk (80.1%) for wearing-off (WO). …”
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17706
Complications, Reoperations, and Nutrient Deficiencies Two Years after Sleeve Gastrectomy
Published 2012-01-01“…Nutritional deficiencies after SG can be detected by routine nutritional screening. Our results show that Vitamin B12 supplementation should suggest routinely after SG.…”
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17707
The Intoxication Effects of Methanol and Formic Acid on Rat Retina Function
Published 2016-01-01“…Concentrations of methanol and formic acid were detected by GC/HS and HPLC, respectively. Results. …”
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17708
UV-Enhanced removal of enrofloxacin in water using oyster shell-derived CaO-ZnO composite
Published 2025-01-01“…The CaO-ZnO composites were synthesized via calcination of oyster shells mixed with zinc oxide and characterized using X-ray diffraction (XRD) to determine their mineral properties. Enrofloxacin was detected at a maximum absorption wavelength of 272 nm using UV-Vis spectroscopy. …”
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17709
Spectrophotometric Determination of Mycophenolate Mofetil as Its Charge-Transfer Complexes with Two π-Acceptors
Published 2012-01-01“…The apparent molar absorptivity values are calculated to be 1.06×103 and 3.87×103 L mol−1 cm−1, respectively, and the corresponding Sandell’s sensitivities are 0.4106 and 0.1119 μg cm−1. The limits of detection (LOD) and quantification (LOQ) are also reported for both methods. …”
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17710
Infections Caused by Actinomyces neuii: A Case Series and Review of an Unusual Bacterium
Published 2016-01-01“…Increased use of MALDI-TOF MS MIS is leading to increased detection; thus, understanding the pathogenicity of this bacterium and its typical susceptibility profile will aid clinical decision-making.…”
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17711
Hardware Efficient Speech Enhancement With Noise Aware Multi-Target Deep Learning
Published 2024-01-01“…For optimal speech denoising, the SE system, trained with multiple-target joint learning, switches between mapping-based, masking-based, or complementary processing, depending on the level of noise contamination detected. Optimisation techniques, including ternary quantisation, structural pruning, efficient sparse matrix representation and cost-effective approximations for complex computations, were implemented to reduce area, memory, and power requirements. …”
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17712
Comparisons of Vitreal Angiogenic, Inflammatory, Profibrotic Cytokines, and Chemokines Profile between Patients with Epiretinal Membrane and Macular Hole
Published 2021-01-01“…Of the 52 tested cytokines, 41 were similar in expression, and 5 were under the detection limit, while 6 cytokines (MMP-8, Eotaxin, MIP-1a, RANTES, TGF-β2, and IL-4) were differently expressed between two groups (p<0.05). …”
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17713
Characterization of marine coral fragment-derived calcium oxide and its performance in chloramphenicol removal from water
Published 2025-01-01“…Chloramphenicol was detected at a maximum absorption wavelength of 278 nm using UV-Vis spectroscopy. …”
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17714
Comparative analysis of galectin-1, galectin-3, and galectin-8 signatures in normal and choriocarcinoma trophoblast cell lines
Published 2024-01-01“…Additionally, different splice variants of galectin-8 were detected across all cell lines. Galectin-1 was predominantly localized at the plasma membrane. …”
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17715
Two complementing in vivo selection systems based on CCA-trimming exonucleases as a tool to monitor, select and evaluate enzymatic features of tRNA nucleotidyltransferases
Published 2025-12-01“…The data show the potential of these RNase-based screening systems, as they allow the detection of enzyme variations that would not have been identified by a conventional rational approach. …”
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17716
Gαq Regulates the Development of Rheumatoid Arthritis by Modulating Th1 Differentiation
Published 2017-01-01“…Gαq negative regulated the differentiation of Th1 cell by modulating the expression of T-bet and the activity of STAT4. Furthermore, we detected the increased ratio of Th1 cells in Gnaq−/− bone marrow (BM) chimeras spontaneously developing inflammatory arthritis. …”
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17717
Diagnostic and Prognostic Impact of Progesterone Receptor Immunohistochemistry: A Study Evaluating More Than 16,000 Tumors
Published 2022-01-01“…PR immunostaining was detected in 57.4% of breast tumors, 28.6% of other gynecological tumors, and 1.8% of nongynecological and nonmammary tumors. …”
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17718
Restoration of a Critical Mandibular Bone Defect Using Human Alveolar Bone-Derived Stem Cells and Porous Nano-HA/Collagen/PLA Scaffold
Published 2016-01-01“…Scanning electron microscopy, a cell proliferation assay, and supernatant detection indicated that the nHAC/PLA provided a suitable environment for aBMSCs. …”
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17719
Luminescence Lifetime-Based Water Conductivity Sensing Using a Cationic Dextran-Supported Ru(II) Polypyridyl Complex
Published 2024-12-01“…The sensor can be interrogated alongside dissolved O<sub>2</sub> and pH luminescent sensors based on the same family of indicator dyes to exploit the definite advantages of luminescence lifetime-based detection.…”
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17720
Analysis of the changes of volatile flavor compounds in a traditional Chinese shrimp paste during fermentation based on electronic nose, SPME-GC-MS and HS-GC-IMS
Published 2023-01-01“…The overall odor profile was detected by the electronic nose. A total of 106 volatile flavor compounds in the shrimp paste samples at different fermentation stages were identified by solid-phase microextraction-gas chromatography-mass spectrometry (SPME-GC-MS) and headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS). …”
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