Patient satisfaction with radio-frequency identification (RFID) tag localization compared with wire localization for nonpalpable breast lesions: the RFID trial by Raphaël Pete, Céleste Pinard, Fanny Sirodot, Ioana Molnar, Margot Dressaire, Angeline Ginzac, Catherine Abrial, Xavier Durando, Marielle Tekath

“…Abstract Background Most breast cancers are detected at an early stage in which case conservative surgery is indicated. …”
Get full text

Comprehensive overview of genotype distribution and prevalence of human papillomavirus in cervical lesions by Yang Liu, Chengquan Zhao, Tiannan Wang, Yuhong Ye, Terrel Jones, Xianxu Zeng

“…This review aims to provide a comprehensive summary detailing the distribution and profile of HPV genotypes detected in cervical lesions, leveraging insights from histological and cytological findings. …”
Get full text

Association between sex steroid hormones and α-klotho: Results from the NHANES 2013-2016 and Mendelian randomization study by Andong Guo, Pengcheng Chen, Jishuang Cao, Chenrui Wu, Sentai Ding

“…Results: In men, significant positive correlations with α-Klotho were consistent across both unadjusted and fully adjusted models for total testosterone (TT), bio-available testosterone (Bio-T), estradiol (E2) and sex hormone-binding globulin (SHBG) (Model 3: TT: β = 3.54, 95 % CI: 1.63–5.44, P = 0.0003; Bio-T: β = 1.74, 95 % CI: 0.73–2.74, P = 0.0007; E2: β = 0.25, 95 % CI: 0.11–0.38, P = 0.0003; SHBG: β = 0.95, 95 % CI: 0.63–1.27, P < 0.0001); In premenopausal women, we detected a potential nonlinear relationship between TT levels and α-Klotho, with α-Klotho levels rising to a peak at a TT level of 72.2 ng/mL, after which they declined. …”
Get full text

Exploring dental students' knowledge on oral cancer prevention: a cross-sectional study in Moldova, Armenia, and Belarus by Olga Golburean, Diana Uncuta, Gayane Manrikyan, Natalia Shakavets, Izabella Vardanyan, Marina Markaryan, Ferda Özkaya, Daniela-Elena Costea, Tarig Al-Hadi Osman

“…Dentists play a vital role in early detection of OC through oral mucosal examination, and in informing the patients about avoidable risk factors of the disease, such as tobacco and excessive alcohol use. …”
Get full text

The Diagnostic Value of Plasma NETs Levels and iCEB in Silent Myocardial Ischemia in Maintenance Hemodialysis Patients by Liu H, Han J, Ni W, Lu Y, Hu X, Wang J, Zhou Y, Wang Z, Cao J, Liu H

“…The ROC analysis demonstrated the potential diagnostic accuracies of NETs levels and iCEB, with an area under the curve (AUC) of 0.908, sensitivity of 0.987, and specificity of 0.829 for identifying SMI.Conclusion: The study highlights the combined diagnostic value of plasma NETs levels and iCEB in identifying SMI in MHD patients, providing valuable insights into potential early detection and risk stratification strategies for this population.Keywords: silent myocardial ischemia, hemodialysis, neutrophil extracellular traps, index of cardiac electrophysiological balance, diagnostic value, cardiovascular complications…”
Get full text

Sistem Identifikasi Penyakit Paru Obstruktif Kronik (PPOK) Berdasarkan Suara Paru-Paru Menggunakan Jaringan Saraf Tiruan Berbasis Raspberry Pi by Lindhu Parang Kusuma, Barlian Henryranu Prasetio, Eko Setiawan

“…This system works by detecting whether the sound of the lungs is COPD infected or healthy. …”
Get full text

Serum IL-1<mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math>, IL-2, and IL-6 in Insulin-Dependent Diabetic Children

“…In all stages of diabetes higher levels of IL-1<mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math> and TNF-<mml:math alttext="$alpha $"> <mml:mi>&#x03B1;</mml:mi> </mml:math> and lower levels of IL-2 and IL-6 were detected. Our data about elevated serum IL-1<mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math>, TNF-<mml:math alttext="$alpha $"> <mml:mi>&#x03B1;</mml:mi> </mml:math> and decreased IL-2, IL-6 levels in newly diagnosed IDDM patients in comparison with longer standing cases supports an activation of systemic inflammatory process during early phases of IDDM which may be indicative of an ongoing <mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math>-cell destruction. …”
Get full text

YEARS clinical decision rule for diagnosing pulmonary embolism: a prospective diagnostic cohort follow-up study in primary care by Frans H Rutten, Menno V Huisman, Jeanet Blom, Rosanne van Maanen, Frederikus A Klok, Geert-Jan Geersing, Karel Moons, Hannah M la Roi-Teeuw, Melchior Nierman, Tuur Egbers

“…In those classified as ‘imaging needed’, PE was present in about one in every four patients, demonstrating a high detection proportion.…”
Get full text

Genome-wide identification of the Sec14 gene family and the response to salt and drought stress in soybean (Glycine max) by Jinyu Zhang, Liying Zou, Li Wang, Dongchao Zhang, Ao Shen, Yongqi Lei, Maoni Chao, Xinjuan Xu, Zhiwei Xue, Zhongwen Huang

“…A total of 10 conserved protein motifs were detected within GmSec14 proteins, with each subfamily possessing unique motifs. …”
Get full text

A case-control genome-wide association study of estimated breeding values for resistance to gastrointestinal nematodes in two local dairy sheep breeds by C. Persichilli, S. Biffani, G. Senczuk, M. Di Civita, M.K. Bitew, A. Bosco, L. Rinaldi, S. Grande, G. Cringoli, F. Pilla

“…Among these, genes involved in the physiology or pathology of the gastrointestinal tract, in adaptive processes and in production traits, were detected. The enrichment analysis highlighted 36 significant pathways in the Comisana breed and 21 in the Massese breed. …”
Get full text

Genetic counselling in the era of next generation sequencing by Diego Espada-Musitu, África Manero-Azua, Yerai Vado, Guiomar Perez de Nanclares

“…Advances in next-generation sequencing (NGS) technologies have made the detection of the molecular causes of paediatric diseases increasingly affordable, accessible and rapid. …”
Get full text

Early Electroacupuncture Extends the rtPA Time Window to 6 h in a Male Rat Model of Embolic Stroke via the ERK1/2-MMP9 Pathway by Xin-chang Zhang, Ya-hui Gu, Wen-tao Xu, Yang-yang Song, Ao Zhang, Zhi-hui Zhang, Si-yuan Jiang, Si-qi Chang, Guang-xia Ni

“…Western blotting and immunofluorescence staining were performed to detect the levels of proteins involved in the ERK1/2 signaling pathway (MEK1/2 and ERK1/2), tight junction proteins (Claudin5 and ZO-1), and MMP9 in the ischemic penumbra at 24 h after stroke. …”
Get full text

Reduced Circulating Levels of miR-491-5p and miR-485-3p Are Associated with the Occurrence of Vertebral Fractures in Postmenopausal Women with Osteoporosis by Jixi Xu, Mingbo Li, Wei Pei, Jinyong Ding, Yueran Pan, Huifeng Peng, Shiman Lin, Yanbo Huang

“…The plasma levels of bone metabolic markers, 25-hydroxyvitamin D (25-(OH)VitD), propeptide of type I procollagen (PINP), and β-Carboxyl terminal peptide (β-CTx), were detected using the patented electro-chemiluminescence (ECLIA) method. …”
Get full text

Evaluation of Six Novel Protein Sources on Apparent Digestibility in Pacific White Shrimp, Litopenaeus vannamei by Xiaoyue Li, Yongkang Chen, Chaozhong Zheng, Shuyan Chi, Shuang Zhang, Beiping Tan, Shiwei Xie

“…The yttrium oxide was used as an exogenous indicator for apparent digestibility detection. Six hundred and thirty healthy and uniform-sized shrimp (approximately 3.04±0.01 g) were randomly distributed into triplicate groups of 30 shrimp and they were fed three times daily. …”
Get full text

Genotype by environment interactions and phenotypic traits stability of the EUCLEG faba bean collection by Dejan Sokolović, Snežana Babić, Mirjana Petrović, Ignacio Solís, Mathias Cougnon, Natalia Gutierrez, Pertti Pärssinen, Dirk Reheul, Jasmina Radović, Ana M. Torres

“…Significant differences among genotypes and environments were detected, being the genotype x environment interaction (GEI) the major source of variation in five of the nine evaluated traits. …”
Get full text

The appearance of scalp high‐frequency oscillations is associated with poor seizure control in pediatric epilepsy patients by Keisuke Maeda, Nami Hosoda, Himari Tsuboi, Honoka Naito, Chiaki Kudo, Junichi Fukumoto, Shiho Fujita, Naohiro Ichino, Keisuke Osakabe, Keiko Sugimoto, Shunta Yamaguchi, Naoko Ishihara

“…Results Scalp HFO was seen more commonly and with a significantly higher detection rate in patients with poor seizure control as compared with patients with good seizure control for both ripple and fast ripple. …”
Get full text

Prevalence and determinants of clustering of adverse lifestyle behaviors among 35 – 75 years old residents at high cardiovascular disease risk in Hebei province: an analysis of dat... by Yuejing QIAO, Yuhuan LIU, Lijuan TANG, Dongsheng JIANG, Xiaoli LIU, Ze CUI

“…MethodsInformation on 29 721 residents aged 35 – 75 years who were considered at high risk of CVD was collected from the datasets of the CVD Early Detection and Comprehensive Intervention Project, which was conducted in 11 sites in Hebei province from 2018 to 2021. …”
Get full text

PU.1 alleviates the inhibitory effects of cigarette smoke on endothelial progenitor cell function and lung-homing through Wnt/β-catenin and CXCL12/CXCR4 pathways by Xue He⁺, Yanan Cui⁺, Tiao Li, Lijuan Luo, Zihang Zeng, Yiming Ma, Yan Chen

“…Flow cytometry was performed to detect EPC count in lung tissues and bone marrow (BM). …”
Get full text

Assessment of Some Physicochemical Parameters and Heavy Metals in Hand-Dug Well Water Samples of Kafta Humera Woreda, Tigray, Ethiopia by Kiros Gebremichail Gebresilasie, Goitom Gebreyohannes Berhe, Amanual Hadera Tesfay, Samuel Estifanos Gebre

“…Out of the selected seven heavy metals, Fe, Cu, Zn, Mn, Cr, Cd, and Pb, only iron was detected in all water samples and its concentration was above the permissible limit of WHO and ESA for drinking water. …”
Get full text

Engagement féminin en Kabylie et intersection des revendications (1980-2001). Dominations, expériences et négociations identitaires by Margherita Rasulo

“…By going beyond the historical invisibility of the Kabyle women’s movement, this approach allows us to detect a process, non-linear in its evolution and still under construction, of change and evolution of gender relations that is reflected in the renegotiation of gender identities and the intersection of the claims of those studied.What these movements have in common is that, since the country’s independence, they have been confined by the state to the status of minority groups. …”
Get full text