The modern options of chronic hepatitis C antiviral therapy with daclatasvir: results of named patient program by V. T. Ivashkin, M. V. Mayevskaya, D. T. Abdurakhmanov, I. G. Bakulin, N. I. Geyvandova, M. L. Zubkin, S. N. Kizhlo, A. V. Kuznetsova, I. B. Latysheva, N. A. Mamonova, V. G. Morozov, O. I. Sagalova, Ye. V. Esaulenko, Ye. O. Lyusina

“…No significant elevation of alanine transaminase and aspartate aminotransferase activity, or bilirubin level were detected. Conclusions. Daclatasvir combination to asunaprevir or sofosbuvir demonstrated high efficacy, including that at treatment of patients with poor prognostic signs.…”
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Discovery of the microbiota-gut-brain axis mechanisms of acupuncture for amnestic mild cognitive impairment based on multi-omics analyses: A pilot study by Zi-Han Yin, Qiong-Nan Bao, Ya-Qin Li, Yi-Wei Liu, Zi-Qi Wang, Fang Ye, Xia He, Xin-Yue Zhang, Wan-Qi Zhong, Ke-Xin Wu, Jin Yao, Zi-Wen Chen, Ling Zhao, Fan-Rong Liang

“…In addition, multi-omics was performed to detect changes in brain function, gut microbiota, and serum metabolites. …”
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The Impact of Training Intervention on Levels of Indicator Bacteria and Prevalence of Selected Pathogens in Raw Milk From Smallholder Women Dairy Farmers in Central Ethiopia by Achenef Melaku Beyene, Seleshe Nigatu, Juan C. Archila-Godinez, Kebede Amenu, Barbara Kowalcyk, Desalegne Degefaw, Binyam Mogess, Baye Gelaw, Mucheye Gizachew, Araya Mengistu, Ahmed G. Abdelhamid, James Barkley, Ahmed Yousef

“…In conclusion, reductions in the detection of some milk quality and safety parameters were observed. …”
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Evaluation of phosphate sources using ruminal fiber transit kinetics methodology by Claudiney de Jesus Couto, Bruna Cardoso Braga, Raphael dos Santos Gomes, Wagner Pessanha Tamy, Severino Delmar Junqueira Villela, Fernando de Paula Leonel, Fernando de Paula Leonel

“…The longest retention time (p<0.05) of solid particles in the rumen-reticulum was detected in animals that received NC diet. In conclusion, heifers that do not receive supplemental phosphorus exhibited poorer fiber processing and dry matter intake (DMI).…”
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3D nanocomposites of β-TCP-H3BO3-Cu with improved mechanical and biological performances for bone regeneration applications by Sarvesh Kumar Avinashi, Rajat Kumar Mishra, Shweta, Saurabh Kumar, Amreen Shamsad, Shama Parveen, Surajita Sahu, Savita Kumari, Zaireen Fatima, Sachin Kumar Yadav, Monisha Banerjee, Monalisa Mishra, Neeraj Mehta, Chandki Ram Gautam

“…Genotoxicity and cytotoxicity tests were also performed on rearing Drosophila melanogaster, and these findings did not detect any trypan blue-positive staining, which further recommended that the existence of composites did not harm the larval gut. …”
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Understanding the mechanisms of hypoxia-induced tissue damage in fish: The role of GasderminEa/b in Larimichthys crocea by Lin Wang, Shuaiyu Chen, Yongyang Wang, Weini Zhang, Yinnan Mu, Yudong Jia, Changtao Guan, Meng Xue, Xinhua Chen

“…Furthermore, after 48 ​h of hypoxia stress, approximately 65% liver cells exhibited abnormalities, with pyroptosis being detected using a transmission electron microscope. …”
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Reproductive Performance in a Selected Sample of Dairy Farms in Una-Sana Canton, Bosnia and Herzegovina by Adis Softic, Adam Dunstan Martin, Eystein Skjerve, Nihad Fejzic, Teufik Goletic, Aida Kustura, Erik Georg Granquist

“…This is an indication of very good oestrus detection in selected dairy farms. The mean number of services per pregnancy was 2.61 (range 1–12). …”
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In Vivo MRI Tracking of Mesenchymal Stromal Cells Labeled with Ultrasmall Paramagnetic Iron Oxide Particles after Intramyocardial Transplantation in Patients with Chronic Ischemic... by Anders Bruun Mathiasen, Abbas Ali Qayyum, Erik Jørgensen, Steffen Helqvist, Annette Ekblond, Michael Ng, Kishore Bhakoo, Jens Kastrup

“…The treatment was safe, and cells were detectable at injection sites up to 14 days after transplantation. …”
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Angiotensin IV Receptors in the Rat Prefrontal Cortex: Neuronal Expression and NMDA Inhibition by Zsolt Tamás Papp, Polett Ribiczey, Erzsébet Kató, Zsuzsanna E. Tóth, Zoltán V. Varga, Zoltán Giricz, Adrienn Hanuska, Mahmoud Al-Khrasani, Ákos Zsembery, Tibor Zelles, Laszlo G. Harsing, László Köles

“…Results: AT4R/IRAP expression was detected in pyramidal cells and GABAergic interneurons, but not in microglia or astrocytes, in layer V of the PFC in 9–12-day-old and 6-month-old rats. …”
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The Late Orchid Catches the Bee: Frost Damage and Pollination Success in the Face of Global Warming in a European Terrestrial Orchid by Florian P. Schiestl, Beat A. Wartmann, Ruth Bänziger, Brigitte Györög‐Kobi, Klaus Hess, Jürg Luder, Edith Merz, Beat Peter, Max Reutlinger, Tobias Richter, Heinz Senn, Thomas Ulrich, Beate Waldeck, Claudia Wartmann, Roland Wüest, Walter Wüest, Quint Rusman

“…Our study shows that the orchid, despite being limited to warm habitats in central Europe, suffers under global warming by increased frost damage caused by earlier flowering. We did not detect an effect of accelerated flowering on desynchronization in flowering time and pollinator activity in this orchid species.…”
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Clinical Recommendations of Russian Gastroenterological Association and RENDO Endoscopic Society on Diagnosis and Treatment of Gastritis and Duodenitis by V. T. Ivashkin, I. V. Maev, T. L. Lapina, E. D. Fedorov, A. A. Sheptulin, A. S. Trukhmanov, A. V. Kononov, R. A. Abdulkhakov, O. P. Alexeeva, S. A. Alekseenko, D. N. Andreev, E. K. Baranskaya, N. N. Dekhnich, I. L. Klyaritskaya, R. S. Kozlov, E. A. Kogan, M. P. Korolev, N. V. Korochanskaya, S. A. Kurilovich, M. A. Livsan, M. F. Osipenko, P. V. Pavlov, S. S. Pirogov, A. S. Sarsenbaeva, V. I. Simanenkov, A. S. Tertychny, A. V. Tkachev, Yu. P. Uspensky, I. B. Khlynov, V. V. Tsukanov

“…Oesophagogastroduodenoscopy (OGDS) or high-resolution OGDS with magnified or non-magnified virtual chromoendoscopy, including targeted biopsy for atrophy and intestinal metaplasia grading and neoplasia detection, are recommended to verify gastritis and duodenitis, precancer states and/or gastric mucosal changes. …”
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Omics-Based Comparison of Fungal Virulence Genes, Biosynthetic Gene Clusters, and Small Molecules in <i>Penicillium expansum</i> and <i>Penicillium chrysogenum</i> by Holly P. Bartholomew, Christopher Gottschalk, Bret Cooper, Michael R. Bukowski, Ronghui Yang, Verneta L. Gaskins, Dianiris Luciano-Rosario, Jorge M. Fonseca, Wayne M. Jurick

“…Molecules with varying biological activities, and phytohormone-like compounds were detected for the first time in <i>P. expansum</i> while antibiotics like penicillin G and other biologically active molecules were discovered in <i>P. chrysogenum</i> culture supernatants. …”
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Cooperation Between <i>Rhodococcus qinshengii</i> and <i>Rhodococcus erythropolis</i> for Carbendazim Degradation by Roosivelt Solano-Rodríguez, Fortunata Santoyo-Tepole, Mario Figueroa, Voleta Larios-Serrato, Nora Ruiz-Ordaz, Abigail Pérez-Valdespino, Everardo Curiel-Quesada

“…The alternative gene for the first catabolic step (<i>mhe</i>I) was detected by PCR in strain RC9 but not in RC1. Metabolomic analysis by HPLC and LC-MS showed that both strains have the ability to metabolize carbendazim. …”
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Cytoplasmic genetic diversity of potato varieties bred in Russia and FSU countries by Т. A. Gavrilenko, N. S. Klimenko, N. V. Alpatieva, L. I. Kostina, V. A. Lebedeva, Z. Z. Evdokimova, O. V. Apalikova, L. Y. Novikova, O. Yu. Antonova

“…Fragments of the  nad2, nad7, cox2, atp6 and  CcmFc genes  were identical  in all 15 selected genotypes. The polymorphism, detected in the rps3, atp9 and CcmFc loci, was not associated with male sterility. …”
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RIPK2-Mediated Autophagy and Negatively Regulated ROS-NLRP3 Inflammasome Signaling in GMCs Stimulated with High Glucose by Chenlin Gao, Jiao Chen, Fang Fan, Yang Long, Shi Tang, Chunxia Jiang, Jiying Wang, Youhua Xu, Yong Xu

“…Autophagosomes were measured by GFP-RFP-LC3; ROS were detected by DCFH-DA. Results. High glucose upregulated RIPK2 and LC3 in GMCs during short periods (0-12 h) (p<0.01), while RIPK2 and LC3 were significantly downregulated in the long term (12-72 h) (p<0.01); these changes were positively correlated with glucose concentration (p<0.01). …”
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High clinical utility of long-read sequencing for precise diagnosis of congenital adrenal hyperplasia in 322 probands by Yunpeng Wang, Gaohui Zhu, Danhua Li, Yu Pan, Rong Li, Ting Zhou, Aiping Mao, Libao Chen, Jing Zhu, Min Zhu

“…Concordant results were detected in 85.42% (82/96) of probands. T-LRS performed more precise diagnosis in 14.58% (14/96) of probands. …”
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Incidence and temporal patterns of true recurrences and second primaries in women with breast cancer: A 10-year competing risk-adjusted analysis by Silvia Mancini, Lauro Bucchi, Annibale Biggeri, Orietta Giuliani, Flavia Baldacchini, Alessandra Ravaioli, Federica Zamagni, Fabio Falcini, Rosa Vattiato

“…Results: The cumulative incidence was 13.7 % (95 % confidence interval (CI), 12.2–15.3 %) for TRs and 4.6 % (95 % CI, 3.7–5.7 %) for SBCs. The median time to detection varied between 3.4 (TRs) and 5.1 (SBCs) years. …”
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Differential diversity and structure of autotrophs in agricultural soils of Qinghai Province by Lianyu Zhou, Xuelan Ma, Qiaoyu Luo, Feng Qiao, Huichun Xie, Longrui Wang, Wenjuan Sun, Yu Liu, Yun Ma

“…No significant biomarkers were detected in any of the crop groups. Some soil properties had significant relationships with the autotrophic bacterial community composition.IMPORTANCEAgricultural soil plays important roles in carbon fixation during carbon capture and storage. …”
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Pathogen community composition and co-infection patterns in a wild community of rodents by Abbate, Jessica L., Galan, Maxime, Razzauti, Maria, Sironen, Tarja, Voutilainen, Liina, Henttonen, Heikki, Gasqui, Patrick, Cosson, Jean-François, Charbonnel, Nathalie

“…Aggregation of pathogens responsible for zoonotic diseases suggests that some rodent species may be more important for transmission risk than others. Moreover, we detected positive associations between several pathogens, including Bartonella, Mycoplasma species, Cowpox virus (CPXV) and hantaviruses, and these patterns were generally specific to particular host species. …”
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Concentration and Potential Sources of Total Gaseous Mercury in a Concentrated Non-Ferrous Metals Smelting Area in Mengzi of China by Xinyu Han, Yuqi Xie, Haojie Su, Wei Du, Guixin Du, Shihan Deng, Jianwu Shi, Senlin Tian, Ping Ning, Feng Xiang, Haitao Xie

“…Simultaneously, the concentrations of TGM in ambient air around these industries and Xidu Tunnel were also detected, the concentrations were 1 to 4 times higher than that in the urban air sampling site. …”
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