In Situ X-Ray Study During Thermal Cycle Treatment Combined with Complementary Ex Situ Investigation of InGaN Quantum Wells by Ewa Grzanka, Sondes Bauer, Artur Lachowski, Szymon Grzanka, Robert Czernecki, Byeongchan So, Tilo Baumbach, Mike Leszczyński

“…This, in turn, has strongly influenced the intensity of the photoluminescence emission spectra without any detectable shift in the emission wavelength λ_MQWs.…”
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Antiviral Activity of Plant‐Based Additives Against African Swine Fever Virus (ASFV) in Feed Ingredients by Thi Ngoc Ha Lai, Thi Bich Ngoc Trinh, Thi Tam Than, Nguyen Tuan Anh Mai, Niku Moussavi Biuki, Bernhard Eckel, Viktor P. L. Eckel, Thi Lan Nguyen, Van Phan Le

“…In Phyto.A04 with 1%, the virus was only detectable on day 1 (3.53 log10 HAD50/mL). Phyto.B with 0.01% and 0.05% both showed good efficacy in completely inhibiting virus presence on days 3 and 7. …”
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Personalized optimization of systematic prostate biopsy core number based on mpMRI radiomics features: a large-sample retrospective analysis by Zhenlin Chen, Zhihao Li, Ruiling Dou, Shaoqin Jiang, Shaoshan Lin, Zequn Lin, Yue Xu, Ciquan Liu, Zijie Zheng, Yewen Lin, Mengqiang Li

“…This method can enhance patient experience without reducing tumor detection rate.…”
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Epigenome-wide DNA methylation profiling in septic and non-septic patients with similar infections: potential use as sepsis biomarkers by Ian López-Cruz, Ian López-Cruz, José Luis García-Giménez, José Luis García-Giménez, José Luis García-Giménez, Manuel Madrazo, Manuel Madrazo, Judit García-Guallarte, Laura Piles, Federico V. Pallardó, Federico V. Pallardó, Federico V. Pallardó, Arturo Artero, Arturo Artero

“…Notably, SLX4 hypomethylation showed the highest predictive value for poor prognosis (AUC 0.821), while SERPINA1 hypomethylation exhibited strong diagnostic potential for sepsis (AUC 0.858).DiscussionOur results underscore the potential of DNA methylation changes, particularly in immune-related genes, to enhance the early detection of sepsis and to stratify patients based on severity. …”
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Genome‐Wide Diversity in Lowland and Highland Maize Landraces From Southern South America: Population Genetics Insights to Assist Conservation by Pia Guadalupe Dominguez, Angela Veronica Gutierrez, Monica Irina Fass, Carla Valeria Filippi, Pablo Vera, Andrea Puebla, Raquel Alicia Defacio, Norma Beatriz Paniego, Veronica Viviana Lia

“…FNEA showed low Ne values and high F values, while HNWA showed low Ne values and low Pi values, indicating that further genetic erosion is imminent for these landraces. Outlier detection methods allowed identification of putative adaptive genomic regions, consistent with previously reported flowering‐time loci and chromosomal regions displaying introgression from the teosinte Zea mays ssp. mexicana. …”
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Latent class cluster analysis of knowledge on acute myocardial infarction in community residents: a cross-sectional study in Tianjin, China by Jing Wang, Xu Zhang, Yan Zhang, Jing Ma, Nan Zhang, Yuan Wang, Jing Gao, Jian-yong Xiao, Yin Liu, Ji-xiang Wang, Xiao-wei Li, Ming-dong Gao, Jing-xian Wang, Shi-bo Xu

“…Identification of Knowledge Clusters could be a way to detect specific targeted groups with low knowledge of AMI, which may facilitate health education, further reduce the prehospital delay in China and improve patient outcomes.…”
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Early impairment of magnocellular visual pathways mediated by isolated-check visual evoked potentials in primary open-angle glaucoma: a cross-sectional study by Yangfan Yang, Minbin Yu, Zidong Chen, Qiaona Ye, Yanmei Fan, Pingping Liu, Zitian Liu, Kezheng Xu

“…Receiver-operating-characteristic (ROC) curves were used to estimate the accuracy in detection of early POAG.Results 60 participants (30 early POAG eyes and 30 age-matched control subjects) were recruited. …”
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Care Complexity Factors and Discharge Destination in an Emergency Department: A Retrospective Cohort Study by Andrea Urbina, Jordi Adamuz, Maria-Eulàlia Juvé-Udina, Judith Peñafiel-Muñoz, Virginia Munoa-Urruticoechea, Maribel González-Samartino, Pilar Delgado-Hito, Javier Jacob, Marta Romero-García

“…Health professionals should consider these relationships for the design of early detection strategies and as an aid in decision-making, to ensure equity and quality of care. …”
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The Role of OCT Angiography in the Assessment of Epiretinal Macular Membrane by Daniela Bacherini, Francesco Dragotto, Tomaso Caporossi, Chiara Lenzetti, Lucia Finocchio, Alfonso Savastano, Maria Cristina Savastano, Francesco Barca, Martina Dragotto, Lorenzo Vannozzi, Francesco Nasini, Francesco Faraldi, Stanislao Rizzo, Gianni Virgili, Fabrizio Giansanti

“…Conclusions. In our study, OCTA detected vascular alterations induced by the presence of the ERM, allowing several correlations with functional data. …”
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Phenolic and Iridoid Glycosides from <i>Leonurus cardiaca</i> L. and Their Effects on the α, δ, and γ Subtypes of the PPAR System—Including the Discovery of the Novel Phenylethanoi... by Kenny Kuchta, Nobuyasu Matsuura, Tung Huu Nguyen, Christian Rusch, Munekazu Iinuma, Yukihiro Shoyama, Hans Wilhelm Rauwald

“…Eight phenylethanoid glycosides not previously detected in <i>L. cardiaca</i>, including the novel cardiaphenyloside A, as well as the iridoids ajugol and harpagide were found via bioassay-guided isolation and structural elucidation of spectroscopic and chemical evidence. …”
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Antimicrobial Residues in Poultry Litter: Assessing the Association of Antimicrobial Persistence with Resistant <i>Escherichia coli</i> Strains by Paula Cortés, Ekaterina Pokrant, Karina Yévenes, Aldo Maddaleno, Andrés Flores, María Belén Vargas, Lina Trincado, Matías Maturana, Lisette Lapierre, Javiera Cornejo

“…<b>Results</b>: Chemical analysis detected concentrations of antimicrobials throughout post treatment, reaching maxima of 42,910.14 μg kg⁻¹, 92,712 μg kg⁻¹, and 9567 μg kg⁻¹ for sulfachloropyridazine, oxytetracycline plus 4-epi-oxytetracycline, and enrofloxacin plus ciprofloxacin, respectively. …”
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Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma by Seema Chugh, Jean C. Tien, Jennifer Hon, Carson Kenum, Rahul Mannan, Yunhui Cheng, Chi Chiang Li, Zainab I. Taher, Andrew D. Delekta, Pushpinder Singh Bawa, Ingrid J. Apel, Stephanie J. Miner, Xuhong Cao, Rohit Mehra, Saravana M. Dhanasekaran, Yuanyuan Qiao, Rajen Mody, Arul M. Chinnaiyan

“…More than half of patients have metastases detected at diagnosis, and high-risk disease is associated with five-year survival rates of only 50–60 %. …”
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Protocol for the enhanced management of multimorbid patients with COPD and severe asthma: role of indoor air quality by Emili Vela, Isaac Cano, Josep Roca, Antoni Sisó-Almirall, Carme Hernandez, Ebymar Arismendi, Ramon Farré, Alba Gómez-López, María Figols, Antonio Montilla-Ibarra, Núria Sánchez-Ruano, Benigno Sánchez, Marta Sorribes, Jordi Piera-Jiménez, Jaume Benavent, Jose Fermoso, Rubèn González-Colom

“…The inconclusive results of preventive strategies in patients with chronic obstructive respiratory disorders and comorbidities are explainable by multifactorial but actionable factors.The current protocol (January 2024–December 2025) relies on the hypothesis that intertwined actions in four dimensions: (1) management change, (2) personalisation of the interventions based on early detection/treatment of acute episodes and enhanced management of comorbidities, (3) mature digital support and (4) comprehensive assessment, can effectively overcome most of the limitations shown by previous preventive strategies. …”
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Limitations of the Boston Carpal Tunnel Questionnaire in Assessing Severity in a Homogeneous Occupational Cohort by Venera Cristina Dinescu, Marius Bica, Ramona Constantina Vasile, Andrei Gresita, Bogdan Catalin, Alexandra Daniela Rotaru-Zavaleanu, Florentin Ananu Vreju, Lorena Sas, Marius Bunescu

“…<b>Objective</b>: This study aimed to evaluate the utility of the BCTQ in a homogeneous cohort of female workers engaged in repetitive manual tasks, exploring its correlation with objective clinical measures and its performance in detecting CTS severity. <b>Methods</b>: A cross-sectional study was conducted on 24 right-hand-dominant female workers with repetitive occupational tasks. …”
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Can muscle synergies shed light on the mechanisms underlying motor gains in response to robot-assisted gait training in children with cerebral palsy? by Gloria P. Vergara-Diaz, Stefano Sapienza, Jean-François Daneault, Eric Fabara, Catherine Adans-Dester, Giacomo Severini, Vincent C. K. Cheung, Carmen Echevarría Ruiz de Vargas, Donna Nimec, Paolo Bonato

“…Results Three and, less often, two muscle synergies were detected in study participants pre-RGT. Linear mixed effect models showed that composition of the muscle synergies and their temporal activation coefficients present deviations from normative data proportional to the severity of functional limitations (i.e., GMFCS levels, p < 0.01). …”
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Exploring cognitive and neuroimaging profiles of dementia subtypes of individuals with dementia in the Democratic Republic of Congo by Jean Ikanga, Jean Ikanga, Saranya Sundaram Patel, Saranya Sundaram Patel, Megan Schwinne, Caterina Obenauf, Caterina Obenauf, Emmanuel Epenge, Guy Gikelekele, Nathan Tshengele, Immaculee Kavugho, Samuel Mampunza, Lelo Mananga, Charlotte E. Teunissen, Julio C. Rojas, Brandon Chan, Argentina Lario Lago, Joel H. Kramer, Adam L. Boxer, Andreas Jeromin, Emile Omba, Alvaro Alonso, Alden L. Gross

“…ObjectiveThe 2024 Alzheimer’s Association (AA) research diagnostic criteria for Alzheimer’s Disease (AD) considers fluid biomarkers, including promising blood-based biomarkers for detecting AD. This study aims to identify dementia subtypes and their cognitive and neuroimaging profiles in older adults with dementia in the Democratic Republic of Congo (DRC) using biomarkers and clinical data.MethodsForty-five individuals with dementia over 65 years old were evaluated using the Community Screening Instrument for Dementia and the informant-based Alzheimer’s Questionnaire. …”
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Illuminating a biologics development challenge: systematic characterization of CHO cell-derived hydrolases identified in monoclonal antibody formulations by Melanie Maier, Linus Weiß, Nikolas Zeh, Valerie Schmieder-Todtenhaupt, Alireza Dehghani, Marius Nicolaus Felix, Daniel Heinzelmann, Benjamin Lindner, Moritz Schmidt, Joey Studts, Patrick Schulz, Bernd Reisinger, Kerstin Otte, Matthias Franzreb, Daniel Lakatos, Simon Fischer

“…Ultimately, we compiled our dataset in a risk matrix identifying PAF-AH, LIPA, PPT1, and LPLA2 as highly critical hydrolases based on their cellular expression, detection in purified antibodies, active secretion, and PS degradation activity. …”
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Identification of alterations in the nucleotide sequence of the chromatin remodeling gene PBRM1 in clear cell renal cell carcinoma patients by E. A. Klimentova, I. R. Gilyazova, A. A. Izmailov, I. M. Sultanov, M. A. Bermisheva, V. N. Pavlov, E. K. Khusnutdinova

“…In the PBRM1 gene, two somatic mutations were found (c.233G&gt;A (p.D45N) in exon 2, c.1675-1676delTC in exon 15) which were not described previously, and one known polymorphic variant rs17264436 (in exon 23). The frequency of detected mutations was 0.95 % of cases. Analysis of the allelic association for the polymorphic locus rs17264436 showed a statistically significant increase in the risk of developing advanced kidney cancer in carriers of allele rs17264436*A, which can be used in the development of prognostic marker panels. …”
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Characterization of the Occult Hepatitis B Virus Variants Circulating among the Blood Donors from Eastern India by Avik Biswas, Rajesh Panigrahi, Partha Kumar Chandra, Arup Banerjee, Sibnarayan Datta, Manisha Pal, Subhashish Chakraborty, Prasun Bhattacharya, Sekhar Chakrabarti, Runu Chakravarty

“…HBsAg, HBeAg, anti-HBc, and anti-HBs statuses of the samples were done by ELISA based detection. PCR amplification and sequencing were done to determine HBV genotypes, basal core promoter (BCP), and precore (Pre-C) mutations. …”
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Biomarkers for Predicting Left Atrial or Left Atrial Appendage Thrombus in Anticoagulated Patients with Nonvalvular Atrial Fibrillation by Xue Zhou, Zuolan Wang, Shuang Dou, Kangyin Chen, Enzhao Liu, Tong Liu, Guangping Li, Jingjin Che

“…Although atrial fibrillation (AF) is often associated with thromboembolic complications, there is no definite biomarker for detecting the presence of thrombi in the left atrial (LA) or left atrial appendage (LAA) in patients with nonvalvular atrial fibrillation (NVAF). …”
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