Value of transabdominal ultrasonography for diagnosing functional constipation in children: a systematic review and meta-analysis by Duc Long Tran, Phu Nguyen Trong Tran, Paweena Susantitaphong, Phichayut Phinyo, Palittiya Sintusek

“…Transabdominal ultrasonography is increasingly used as a novel modality for detecting pediatric functional constipation (FC). This systematic review and meta-analysis aimed to assess the diagnostic parameters of FC including rectal diameter (RD) and anterior rectal wall thickness. …”
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Experience of Two-Stage Treatment of Rectal Fistulas Using Low-Thrombin Fibrin Glue “Kriofit” by S. А. Frolov, A. M. Kuzminov, D. V. Vyshegorodtsev, V. Yu. Korolik, I. S. Bogormistrov, A. N. Ryndin

“…According to the sphincterometry data, no anal holding dysfunction was detected in any of 28 patients.Conclusion. The results of our study have shown that the division of preliminary surgical treatment of the fistulous passage followed by local anti-inflammatory treatment and filling of the wound canal with two-component fibrin glue with low thrombin content “Kriofit” into two stages effectively increases the results of the proposed technique. …”
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Designing an intervention to improve cognitive evaluations in primary care by Kyra S. O’Brien, Kristin Harkins, MaryAnne Peifer, Melanie Kleid, Cameron Coykendall, Judy Shea, Jason Karlawish, Robert E. Burke

“…For some patients, early detection of cognitive impairment enables access to disease-modifying therapies. …”
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Factors determining primary or delayed surgery for unilateral, non-metastatic Wilms tumor: a multicentric Egyptian study by Ahmed Elgendy, Amr Abdelhamid AbouZeid, Mohamed El-Debeiky, Shaimaa Abdelsattar Mohammad, Marwa Romeih, Ahmed Ebeed, Mohamed Abouheba, Mohammed Hamada Takrouney, Mahmoud Mostafa, Ahmed Khairi, Osama El-Naggar, Sameh Shehata

“…Intravascular tumor thrombus was detected in 7 patients (6.25%) at various locations. …”
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Efficacy of Novel Noncontrast Cardiac Magnetic Resonance Methods in Indicating Fibrosis in Hypertrophic Cardiomyopathy by Maedeh Sharifian, Nahid Rezaeian, Sanaz Asadian, Ali Mohammadzadeh, Ali Nahardani, Kianosh Kasani, Yaser Toloueitabar, Ali Mohammad Farahmand, Leila Hosseini

“…We evaluated the efficacy of 2 novel contrast-free CMR methods, namely, diffusion-weighted imaging (DWI) and feature-tracking (FT) method, in detecting myocardial fibrosis. Methods. This cross-sectional study was conducted on 26 patients with HCM. …”
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MUNet: a novel framework for accurate brain tumor segmentation combining UNet and mamba networks by Lijuan Yang, Lijuan Yang, Qiumei Dong, Da Lin, Chunfang Tian, Xinliang Lü

“…Brain tumors are one of the major health threats to humans, and their complex pathological features and anatomical structures make accurate segmentation and detection crucial. However, existing models based on Transformers and Convolutional Neural Networks (CNNs) still have limitations in medical image processing. …”
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The usage of personalized scheme of fentanyl administration during coronary artery stenting by D.О. Dziuba

“…The usage of a personalized scheme of fentanyl administration for stenting of the coronary arteries, compared to the standard sedation using combination of diazepam and fentanyl, was accompanied by better indicators of intraoperative blood saturation with oxygen and carbon dioxide (respectively (103.67 ± 22.05) and (39.64 ± 6.85) mm Hg in group 1, (105.70 ± 31.64) and (37.68 ± 7.11) in group 2 and (109.42 ± 34.36) and (36.25 ± 6.52) mm Hg in patients of the 3rd group), lower blood pressure after surgery ((127.85 ± 9.87)/(79.64 ± 8.62) mm Hg in patients of group 1, (129.48 ± 8.73)/(81.05 ± 7.92) mm Hg in group 2 and (131.15 ± 10.64)/(82.68 ± 9.72) mm Hg in group 3), lower level of stress markers (blood cortisol during surgery in patients of the 1st group (8.83 ± 4.58) mmol/L, in patients of the 2nd group – (7.73 ± 2.79) mmol/L, in patients of the 3rd group – (7.55 ± 4.35) mmol/L), as well as lower frequency of detecting episodes of perioperative pain of various origins. …”
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An In Vitro Model of Diabetic Retinal Vascular Endothelial Dysfunction and Neuroretinal Degeneration by Qiyun Wang, Xinyuan Zhang, Kaiyue Wang, Ling Zhu, Bingjie Qiu, Xiaosi Chen, Xiao Lin, Yao Nie

“…RGCs were labeled by neurons and RGC markers TUJ1 and BRN3A for quantitative and morphological analysis. Apoptosis was detected using PI/Hoechst staining and TUNEL assay and quantified by ImageJ. …”
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Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy by Ke C, Yu Y, Li J, Yu Y, Sun Y, Wang Y, Wang B, Lu Y, Tang M, Wang N, Chen Y

“…Then, downstream analyses were performed to detect protein interactions, gene function, cell type-specific expression and druggable information.Results: This study genetically predicted levels of 62 plasma proteins were associated with GD risk. …”
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Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach by Pei Liu, Lin Xu, Jing-han Guo, Jin-hua Chang, Xi-gang Liu, He-fei Xue, Ru-xing Wang, Zhong-si Li, Guang-xin Miao, Cui-zhe Liu, Jian-yu Zhou

“…This approach showed a low limit of quantification of 0.5 ng/ml for diosgenin and could detect this molecule at a concentration range of 0.5 to 1,500 ng/ml (r = 0.99725). …”
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Characterization of Vaginitis Among Women Complaining of Genital Tract Symptoms by Hemin Muheddin Kareem, Muhammed Saed Qadir, Safa Bakr Karim, Solaf Jawhar Ali

“…Therefore, it is essential to perform laboratory examination for the patients to detect the causative agents of vaginitis, and ensure the most appropriate treatment can be administered. …”
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Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs by Elias A. Said, Sumaya Al-Dughaishi, Wadha Al-Hatmi, Iman Al-Reesi, Mohammed S. Al-Balushi, Atika Al-Bimani, Juma Z. Al-Busaidi, Marwa Al-Riyami, Murtadha Al-Khabori, Salam Al-Kindi, Francesco A. Procopio, Shadia Al-Sinawi, Aliyaa Al-Ansari, Crystal Y. Koh, Khalid Al-Naamani, Ali A. Al-Jabri

“…TLRs 3, 7, 8, and 9 are nucleic acid sensing (NAS) TLRs that detect nucleic acids from cell damage and infection and induce iAPC responses. …”
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A nociceptor-specific RNAi screen in Drosophila larvae identifies RNA-binding proteins that regulate thermal nociception by Amber Dyson, Gita Gajjar, Katherine C. Hoffman, Dakota Lewis, Sara Palega, Erik Rangel Silva, James Auwn, Andrew Bellemer

“…Nociception is the process by which sensory neurons detect and encode potentially harmful environmental stimuli to generate behavioral responses. …”
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Improving doublet cell removal efficiency through multiple algorithm runs by Yong She, Chaoye Wang, Qi Zhao

“…We evaluated the MRDR strategy in 14 real-world datasets, 29 barcoded scRNA-seq datasets, and 106 synthetic datasets with four popular doublet detection tools, including DoubletFinder, cxds, bcds, and hybrid. …”
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Surgical treatment of fourth branchial apparatus anomalies: a case series study by Wan-Xin Li, Yanbo Dong, Aobo Zhang, Jun Tian, Cheng Lu, Jean Pierre Jeannon, Liangfa Liu

“…No complication occurred. One recurrence was detected, in the only patient whose internal orifice could not be located pre- or intra-operatively, and the hypopharyngeal attachment could not be removed. …”
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Clinical study of colorViz fusion image vascular grading based on multi-phase CTA reconstruction in acute ischemic stroke by Qi Wang, Qiang Wang, Yunfa Xu, Xue Li, Dingbin Zhou, Xiaotong Sun, Bo Feng

“…This technique allows for relatively accurate detection of the ischemic extent and the likelihood of infarction in the superficial regions where lesions are located.…”
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Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir. by Brandon F Keele, Afam A Okoye, Christine M Fennessey, Benjamin Varco-Merth, Taina T Immonen, Emek Kose, Andrew Conchas, Mykola Pinkevych, Leslie Lipkey, Laura Newman, Agatha Macairan, Marjorie Bosche, William J Bosche, Brian Berkemeier, Randy Fast, Mike Hull, Kelli Oswald, Rebecca Shoemaker, Lorna Silipino, Robert J Gorelick, Derick Duell, Alejandra Marenco, William Brantley, Jeremy Smedley, Michael Axthelm, Miles P Davenport, Jeffrey D Lifson, Louis J Picker

“…Rebounding plasma from the 1 rebounding RM contained only a single barcode lineage detected at day 50 post-ART. All RMs starting ART on days 5 and 6 rebounded between 14- and 50-days post-ART with 1-2 rebounding variants each. …”
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Gene Mining and Genetic Effect Analysis Reveal Novel Loci, <i>TaZn-2DS</i> Associated with Zinc Content in Wheat Grain by Zhuangzhuang Hong, Zhankui Zeng, Jiaojiao Li, Xuefang Yan, Junqiao Song, Qunxiang Yan, Qiong Li, Yue Zhao, Chang Liu, Xueyan Jing, Chunping Wang

“…Among them, <i>QGZn.haust-AH-2D</i> was detected in multiple environments, accounting for 5.61% to 11.27% of the phenotypic variation with a physical interval of 13.62 Mb to 17.82 Mb. …”
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DNM3OS Enhances the Apoptosis and Senescence of Spermatogonia Associated with Nonobstructive Azoospermia by Providing miR-214-5p and Decreasing E2F2 Expression by Rui Hua, Qingjun Chu, Feiyan Guo, Qinjie Chen, Maocai Li, Xuan Zhou, Yongtong Zhu

“…Functional studies performed using the CCK-8 assay, EdU incorporation assay, apoptosis detection, and senescence-associated β-galactosidase (SA-β-Gal) staining were conducted using GC-1 spg cells. …”
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Pendeteksi Citra Masker Wajah Menggunakan CNN dan Transfer Learning by Mohammad Farid Naufal, Selvia Ferdiana Kusuma

“…However, manually checking to detect faces that are not wearing masks is a long and tiring job. …”
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