Transition zone-based prostate-specific antigen density for differentiating clinically significant prostate cancer in PI-RADS score 3 lesions by Yongming Jin, Fei Chen, Gang Xu, Chaogang Wei, Congsong Dong

“…Abstract We intended to investigate the potential of several transitional zone (TZ) volume-related variables for the detection of clinically significant prostate cancer (csPCa) among lesions scored as Prostate Imaging Reporting and Data System (PI-RADS) category 3. …”
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Mechanism and Pharmacodynamic Substance Basis of Raw and Wine-Processed Evodia rutaecarpa on Smooth Muscle Cells of Dysmenorrhea Mice by Yeqian Liu, Hong Li, Lei Chen, Hongxia Zhao, Jian Liu, Shan Gong, Danfeng Ma, Chunming Chen, Shuiqing Zeng, Hongping Long, Weiqiong Ren

“…The cell contraction and the expression of P2X3 and Ca2+ in vitro were determined using immunofluorescence staining and laser confocal; ELISA was used for detection of PGE2, ET-1, and NO content after 7-hydroxycoumarin, chlorogenic acid, and limonin administered for 24 h. …”
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circ-SIRT1 Promotes Colorectal Cancer Proliferation and EMT by Recruiting and Binding to eIF4A3 by Xiangjie Wang, Shuang Liu, Bin Xu, Yabin Liu, Peng Kong, Changlin Li, Binghui Li

“…The expression of circ-SIRT1 in CRC cells and tissue was detected by RT-qPCR. Colony formation and Cell Counting Kit-8 assays were used to evaluate the effect of circ-SIRT1 knockdown on the proliferative ability of CRC cells. …”
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Variational Approaches for Drug-Disease-Gene Links in Periodontal Inflammation by Pradeep Kumar Yadalam, Prabhu Manickam Natarajan, Musab Hamed Saeed, Carlos M. Ardila

“…The VQA model demonstrated a high accuracy rate of 97.5%, although it only detected 50% of anomalies. The VQC model achieved a precision of 78%, with Class 1 samples showing improved recall and a balanced F1 score. …”
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Randomized Controlled Trial of Polyethylene Glycol versus Oral Sodium Phosphate for Bowel Preparation in Unsedated Colonoscopy by Dong Yang, Ke Tao, Geng Chen, Luping Zhang, Qingying He, Hong Xu

“…There were no significant differences in the cecal intubation rate and the detection rate of polyps and ulcers/erosion between the two groups. …”
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Evaluating the impact of ESICM 2023 guidelines and the new global definition of ARDS on clinical outcomes: insights from MIMIC-IV cohort data by Duanhong Song, Qingquan Chen, Shangbin Huang, Shengxun Qiu, Zeshun Chen, Yuanhang Cai, Yifu Zeng, Xiaoyang Chen, Yixiang Zhang

“…Conclusions The new ARDS definition offers advantages in earlier detection, more accurate grading, and more precise diagnosis in resource-limited settings compared with the Berlin definition. …”
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Preliminary exploration of mRNA, lncRNA, and miRNA expressions in the bovine jejunum unveils novel aspects of Mycobacterium avium subspecies paratuberculosis infections by Yahui Gao, Jie Cao, Bo Han, Dongxiao Sun

“…., clinical vs. healthy, subclinical vs. healthy, and clinical vs. subclinical, subsequently identifying ceRNA pairs. Ultimately, we detected 76, 74, and 24 DEGs, 19, 39, and 10 lncRNAs, as well as 28, 61, and 20 miRNAs across the three comparison groups, respectively. …”
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Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation by Anthony G. Matta, Thibault Lhermusier, Francisco Campelo Parada, Frederic Bouisset, Ronan Canitrot, Vanessa Nader, Stéphanie Blanco, Meyer Elbaz, Jerome Roncalli, Didier Carrié

“…The prevalence of coronary artery disease (CAD) detected in preoperative work-up for transcatheter aortic valve implantation (TAVI) is high. …”
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Factors affecting arteriovenous access patency after percutaneous transluminal angioplasty in chronic haemodialysis patients under vascular access monitoring and surveillance: a si... by Chung-Kuan Wu, Der-Cherng Tarng, Chia-Hsun Lin, Jyh-Gang Leu, Chih-Yu Yang

“…In addition to routine monitoring, VA flow surveillance was performed every 3 months for detection of VA dysfunction adhering to Kidney Disease Outcomes Quality Initiative guidelines.Results A total of 508 patients were selected for study inclusion (with PTA, n=231; without PTA, n=277). …”
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Effect of Ethylmethacrylate and Isobutylmethacrylate on Surface Hardness and Surface Roughness of Heat-Cure Ocular Acrylic Resins by Hiba Munaf Hadi, Ayad I. Haddad, Firas Abd kati

“…All data were analyzed using SPSS version 20, One –way ANOVA, LSD and Post Hoc -Tukey test were utilized for detecting the significant differences and multiple comparisons. …”
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Association between the rifampicin resistance mutations and rifabutin susceptibility in Mycobacterium tuberculosis: A meta-analysis by Wenli Wang, Hongjuan Zhou, Long Cai, Tingting Yang

“…Conclusions: These results provide a theoretical basis for the molecular detection of RFB-susceptible tuberculosis and alternative treatment with RFB in patients with multidrug-resistant/rifampicin-resistant tuberculosis.…”
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Concurrent Renorrhaphy During Renal Mass Excision in Laparoscopic Nephron-Sparing Surgery: A Novel Surgical Technique by Nurullah Hamidi, Tuncel Uzel

“…Intraperitoneal air pressure was reduced to detect hidden bleeding. Anti-bleeding powder was applied to the excision area. …”
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Impacts of coal fracture roughness and aperture on the seepage of injected water: An experimental study by Gang WANG, Xuechang CHEN, Hao CHEN, Qingming LONG, Yixin LIU

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Automated characterisation of cerebral microbleeds using their size and spatial distribution on brain MRI by Vaanathi Sundaresan, Giovanna Zamboni, Robert A. Dineen, Dorothee P. Auer, Stamatios N. Sotiropoulos, Nikola Sprigg, Mark Jenkinson, Ludovica Griffanti

“…As one of the important biomarkers of small vessel disease, they have been associated with various neurodegenerative and cerebrovascular diseases. Hence, automated detection, and subsequent extraction of clinically useful metrics (e.g., size and spatial distribution) from CMBs are essential for investigating their clinical impact, especially in large-scale studies. …”
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Precise and interpretable neural networks reveal epigenetic signatures of aging across youth in health and disease by David Martínez-Enguita, Thomas Hillerton, Julia Åkesson, Daniel Kling, Maria Lerm, Mika Gustafsson

“…Here, we propose that the reliability of DNAm age clocks should stem from their capacity to detect comprehensive and targeted aging signatures.MethodsWe compiled publicly available DNAm whole-blood samples (n = 17,726) comprising the entire human lifespan (0–112 years). …”
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Complete mitogenome characteristics and phylogenetic analysis of traditional Chinese medicinal plant Tinospora sagittata (Oliv.) Gagnep. from the Menispermaceae family by Jing Zhao, Zi-Han Chen, Peng-Cheng Huang, Liu-Wei Chen, Ming-Xian Zhang, Li-Hua Wang, You-Yong Zhu, Jia-Guan Wang, Yu Zhao

“…The plastomes were highly similar in gene content and exhibited a typical quadripartite structure, but a translocation as well as two inversions were detected in mitogenomes. The repeats patterns in both organelles are generally similar, but significant difference in the codon bias of the genes of Tinospora organelle genomes. …”
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Influence of Migration and Plugging of Nanoparticles on Coal Permeability in Coal Reservoirs by Xiaopeng Zhai, Weihong Chen, Yun Xu, Yishan Lou, Shuhong Xu, Lihui Zheng, Zhiyang Guo, Yuanchang Chen, Hongyong Hao, Jianfang Jiang

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Brief Report: Precision Language and Deletion of the “S” Word by Ciara Lockstadt, MD, Mary M. Pasquinelli, DNP, Jill Feldman, MD, Jamie L. Studts, PhD, Jamie S. Ostroff, PhD, Li Liu, PhD, Ella A. Kazerooni, MD, Robert A. Smith, PhD, Lisa Carter-Bawa, PhD, Lawrence E. Feldman, MD

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Bone cell differentiation and mineralization in wild-type and osteogenesis imperfecta zebrafish are compromised by per- and poly-fluoroalkyl substances (PFAS) by Francesca Tonelli, Cecilia Masiero, Carla Aresi, Camilla Torriani, Simona Villani, Guido Premoli, Antonio Rossi, Antonella Forlino

“…Limited to WT exposed to PFOA a reduced mineralization was also observed. No effect was detected after PFHxA exposure. Apoptosis was only activated by PFOA, specifically in Chi/+ mutant operculum osteoblasts. …”
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Hairy transcriptional repression targets and cofactor recruitment in Drosophila. by Daniella Bianchi-Frias, Amir Orian, Jeffrey J Delrow, Julio Vazquez, Alicia E Rosales-Nieves, Susan M Parkhurst

“…Similarly, the distributions of loci recruiting each of Hairy's cofactors are detected as cofactor binding sites in vivo on polytene chromosomes. …”
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