Systematic analysis of co-expression network and gene expression profile of differentially expressed lncRNA-mRNA one week after spinal cord injury by Yi Kang, Yijie Song, Zhongju Shi, Qiang Li, Yigang Lv, Mengfan Hou, Cui Ding, Jing Xie, Yongfu Lou, Chi Zhang, Huan Jian, Xueying Li, Hengxing Zhou, Shiqing Feng

“…Abbreviations: SCI: spinal cord injury; CNS: central nervous system; YLDs: years of life lived with disability; lncRNAs: long noncoding RNAs; mRNAs: messenger RNAs; DE: differentially expressed; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; GSEA: gene set enrichment analysis; RIN: Renewable Identification Number; PCA: principal component analysis; PPI: protein–protein interaction; MF, molecular function; BP: biological process; CC: cellular component; MCODE: molecular complex detection…”
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Changing trends from inguinal radical orchiectomy to testis-sparing surgery in pediatric testicular tumors by Özlem Balcı, Aslı Nur Abay, Şule Yeşil, İbrahim Karaman, İsmet Faruk Özgüner, Burçak Kurucu, Derya Erdoğan, Gürses Şahin, Ayşe Karaman

“…Testicular biopsy was performed in 9 cases for testicular involvement of Leukemia and Lymphoma. No recurrence was detected with a median follow-up of 6.5 years. Conclusion Radical inguinal orchiectomy is still the standard surgical treatment for malignant testicular tumors. …”
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Immunomodulatory Effect of Phage Depolymerase Dep_kpv74 with Therapeutic Potential Against K2-Hypervirulent <i>Klebsiella pneumoniae</i> by Nikolay V. Volozhantsev, Maria A. Makarova, Alena S. Kartseva, Marina V. Silkina, Valentina M. Krasilnikova, Egor A. Denisenko, Alexander I. Borzilov, Victoria V. Firstova

“…The depolymerase was detected in the blood, spleen, and lungs of mice 10 min after intraperitoneal administration, reaching maximum activity values after 1–3 h and maintaining activity a day after administration. …”
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CGH, cDNA and Tissue Microarray Analyses Implicate FGFR2 Amplification in a Small Subset of Breast Tumors by Mervi Heiskanen, Juha Kononen, Maarit Bärlund, Joachim Torhorst, Guido Sauter, Anne Kallioniemi, Olli Kallioniemi

“…Applied to a genomic scale with larger arrays, this strategy should facilitate identification of the most important target genes for cytogenetic rearrangements, such as DNA amplification sites detected by conventional CGH. Figures on http://www.esacp.org/acp/2001/22‐4/heiskanen.htm…”
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Reasons for Undesirable Pregnancy Outcomes among Women with Appendicitis: The Experience of a Tertiary Center by Baris Mantoglu, Fatih Altintoprak, Necattin Firat, Emre Gonullu, Enis Dikicier, Yesim Akdeniz, Mehmet Aziret, Unal Erkorkmaz

“…No statistically significant difference was detected in this group in terms of appendicitis pathology triggering preterm delivery or abortion (p 0.075). …”
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The Secondary Component of the Extremely Low Mass Ratio Massive Binary HD 165246 Revealed by GHOST by C. N. Rodriguez, T. Ansin, G. A. Ferrero, O. G. Benvenuto, R. Gamen, N. I. Morrell, J. I. Arias, R. E. Higa, C. Putkuri, C. Johnston, K. Chiboucas, E. Deibert, C. R. Hayes, J.-E. Heo, M. Jeong, V. Kalari, E. Martioli, V. M. Placco, K. A. Venn, S. Xu, R. Diaz, M. Gomez-Jimenez, R. Ruiz-Carmona, C. Simpson, A. W. McConnachie, J. Pazder, G. Burley, T. A. M. Berg, J. G. Robertson, K. Labrie, J. Thomas-Osip

“…Thanks to the high-resolution capabilities of the new echelle spectrograph Gemini/GHOST, we could directly detect spectral features of the secondary component for the first time. …”
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Atacama Large Aperture Submillimeter Telescope (AtLAST) science: Probing the transient and time-variable sky [version 2; peer review: 1 approved, 2 approved with reservations] by Pamela Klaassen, Mark Booth, Thomas Stanke, Evanthia Hatziminaoglou, Claudia Cicone, Martin Cordiner, Tony Mroczkowski, Doug Johnstone, Luca Di Mascolo, Minju Lee, Eelco van Kampen, Thomas Maccarone, Daizhong Liu, Matthew Smith, Amélie Saintonge, Sven Wedemeyer, Alexander Thelen, John Orlowski-Scherer, Tomasz Kamiński, Joe Bright, Atul Mohan, Michael Koss, Sigurd Næss, Francisco Miguel Montenegro-Montes, Paola Severgnini, Claudio Ricci, Jochen Greiner, Cristian Vignali

“…In particular, AtLAST’s large field of view will enable serendipitous detections of transient events, while its anticipated ability to get on source quickly and observe simultaneously in multiple bands make it also ideally suited for transient follow-up. …”
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Artificial intelligence driven clustering of blood pressure profiles reveals frailty in orthostatic hypertension by Claire M. Owen, Jaume Bacardit, Maw P. Tan, Nor I. Saedon, Choon‐Hian Goh, Julia L. Newton, James Frith

“…Given the richness of non‐invasive beat‐to‐beat data, artificial intelligence (AI) offers a solution to detect the subtle patterns within it. Applying machine learning to an existing dataset of community‐based adults undergoing postural assessment, we identified three distinct clusters (iOHYPO, OHYPO and OHYPER) akin to initial and classic orthostatic hypotension and orthostatic hypertension, respectively. …”
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Longitudinal non-targeted metabolomic profiling of urine samples for monitoring of kidney transplantation patients by Ihsan Yozgat, Ulkem Cakır, Muhittin Abdulkadir Serdar, Sevgi Sahin, Osman Ugur Sezerman, Emirhan Nemutlu, Ahmet Tarik Baykal, Mustafa Serteser

“…Based on their 12-month follow-up serum creatinine levels: Group 2 had levels exceeding 1.5 mg/dl, while Group 1 had levels below 1.5 mg/dl. Metabolites were detected by mass spectrometer and first pre-processed. …”
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DOCK4 Is a Platinum-Chemosensitive and Prognostic-Related Biomarker in Ovarian Cancer by Qianqian Zhao, Jie Zhong, Ping Lu, Xiao Feng, Ying Han, Chenqi Ling, Wenke Guo, Weijin Zhou, Fudong Yu

“…Meanwhile, DOCK4 is detected in plasma and enriched in neutrophil and monocyte cells of the blood. …”
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Ramadan during pregnancy and the role of dietary intake for neonatal health in Kaduna, Northwestern Nigeria: a cross-sectional study by Musa Abubakar Kana, Bilkisu Usman, Amina Mohammed-Durosinlorun, Jennifer Ahmed, Hassana Habiba Abubakar, Yakub Abdulmalik, Fabienne Pradella

“…No independent associations were detected between reduced sleep and food intake, and birth weight. …”
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Early health technology assessment of tongue swab for non-sputum based pulmonary tuberculosis diagnosis in ThailandResearch in context by Langming Mou, Teerawat Wiwatpanit, Apiwat Piriyapol, Puwadol Chawengkul, Janjira Thaipadungpanit, Puttarin Kulchaitanaroaj, Yot Teerawattananon, Yi Wang

“…Stakeholders indicated that PTB detection remains inefficient due to issues such as low-test accuracy, costs, delays, drug-resistance testing, and the need for specialized laboratory techniques and personnel. …”
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Multimodal abnormalities of brain function in chronic low back pain: a systematic review and meta-analysis of neuroimaging studies by Xingyao Chen, Xingyao Chen, Xingyao Chen, Nuo Chen, Nuo Chen, Nuo Chen, Peng Lai, Peng Lai, Yiqi Sun, Jie Yu, Ming Xin, Deliang Zhu, Fanrong Liang, Fanrong Liang, Fanrong Liang, Qian Song, Shirui Cheng, Shirui Cheng, Shirui Cheng, Zhengjie Li, Zhengjie Li, Zhengjie Li, Zhengjie Li

“…ObjectivesNeuroimaging investigations into chronic low back pain (CLBP) have detected functional abnormalities across a spectrum of brain regions, yet the findings have often been inconsistent. …”
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Towards New Scaffolds for Antimicrobial Activity—In Silico/In Vitro Workflow Introducing New Lead Compounds by Maria Mangana, George Lambrinidis, Ioannis K. Kostakis, Ioanna Kalpaktsi, Marina Sagnou, Chrysoula Nicolaou, Emmanuel Mikros, Stylianos Chatzipanagiotou, Anastasios Ioannidis

“…For the Gram-negative bacteria, no activity was detected (≥100 µg/mL). <b>Conclusions</b>: The tested scaffolds could be considered as promising candidates for novel antimicrobials with improvements. …”
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Complementary Embryonic and Adult Cell Populations Enhance Myocardial Repair in Rat Myocardial Injury Model by Sergio Li Calzi, Todd Cook, Domenico G. Della Rocca, Juan Zhang, Vinayak Shenoy, Yuanqing Yan, Andrew Espejo, Anandharajan Rathinasabapathy, Max H. Jacobsen, Tatiana Salazar, George E. Sandusky, Lynn C. Shaw, Keith March, Mohan K. Raizada, Carl J. Pepine, Michael J. Katovich, Maria B. Grant

“…In the combination cell group, viable cells were detected at week 4 when anterior wall motion was completely restored. …”
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IFN-γ/TNF-α Synergism Induces Pro-Inflammatory Cytokine and Chemokine Production by In Vitro Canine Keratinocytes by Kyungsook Jung, Ji-Yeong Ku, Je-Seong Kwon, Gayeon Won, Hakyoung Yoon, Sang-Ik Oh, Mi Hye Kim, Chongchan Kim, Ji-Seon Yoon

“…In addition, significantly increased concentrations of CXCL8 were detected in CPEKs incubated with TNF-α and with the IFN-γ/TNF-α mixture. …”
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Alterations in the social-conditioned place preference and density of dopaminergic neurons in the ventral tegmental area in Clsnt2-KO mice by I. N. Rozhkova, S. V. Okotrub, E. Yu. Brusentsev, K. E. Uldanova, E. A. Chuyko, V. A. Naprimerov, T. V. Lipina, T. G. Amstislavskaya, S. Ya. Amstislavsky

“…At the same time, an increased number of DA and possibly GABA neurons labeled with antibodies against the type 2 dopamine receptor as well as against tyrosine hydroxylase were detected in the VTA of the Clstn2-KO mice. Thus, a change in social-conditioned place preference in Clstn2-KO mice as well as a higher number of neurons expressing type 2 dopamine receptors and tyrosine hydroxylase in the VTA, the key structure of the mesolimbic dopaminergic pathway, were observed.…”
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CSF3 promotes colorectal cancer progression by activating p65/NF-κB signaling pathway and inducing an immunosuppressive microenvironment by Junfeng Xu, Na Li, Hui Xie, Changwei Duan, Xingchen Liao, Ruoran Li, Heng Zhang, Yuanming Pan, Xianzong Ma, Shuwen Du, Jianqiu Sheng, Xin Wang, Lang Yang, Peng Jin

“…Methods: CSF3 expression levels in CRC cells and tissues were detected by quantitative real-time PCR (qRT-PCR), western blot and immunohistochemistry (IHC). …”
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Stem cells prevent long-term deterioration of renal function after renal artery revascularization in a renovascular hypertension model in rats by Nikolas Waack, Tatiana Guirao, Edgar Maquigussa, Erika Nishi, Milene Ormanji, Olinda Ykuta, Mirian Boim

“…Treatment with MSCs had no detectable beneficial effects on kidney function or SBP. …”
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Translation and psychometric evaluation of the Danish version of the knee outcome survey - activities of daily living scale in patients with anterior cruciate ligament injuries by Kamilla Arp, Claus Varnum, Ulrik Dalgas, Bettina Mølri Knudsen, Signe Timm, Bjarke Viberg, Kim Gordon Ingwersen

“…Structural validity (factor analysis), Internal consistency (Cronbach`s alpha), construct validity (hypothesis testing), test-retest reliability (Intraclass Correlation Coefficient [ICC]), test-retest agreement (Bland-Altman plots with 95% Limits of Agreement), Standard Error of Measurement (SEM), Smallest Detectable Chance (SDC), responsiveness (construct approach with hypothesis testing) and floor/ceiling effects were assessed. …”
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