Identification of compounds against atherosclerosis induced by ox-LDL based on cell extraction/UPLC–MS/MS from mulberry twigs and their mechanistic analysis by Zhihui Jin, Wei Xiang, Xiaowen Shi, Fenglin Jiang, Yanan Jia, Yuansong Zhang, Lingshu Zeng, Xianzhi Huang, Li Xu

“…Protective effects were assessed by measuring cell viability, malondialdehyde (MDA), and superoxide dismutase (SOD) levels, along with detecting intracellular reactive oxygen species (ROS) using 2, 7-dichlorodihydrofluorescein diacetate (DCFH-DA) and dihydroethidine (DHE) probes. …”
Get full text

Molecular effects of clinically relevant chemotherapeutic agents on choline phospholipid metabolism in triple negative breast cancer cells by Caitlin M. Tressler, Kanchan Sonkar, Menglin Cheng, Vinay Ayyappan, Ruoqing Cai, Kristine Glunde

“…The magnetic resonance spectroscopy (MRS)-detected total choline (tCho) signal was shown to be a promising biomarker for assessing the response to chemotherapy treatment early on, as breast tumor tCho decreases after the first treatment cycle in patients who respond to chemotherapy cocktails. …”
Get full text

The JADES Transient Survey: Discovery and Classification of Supernovae in the JADES Deep Field by Christa DeCoursey, Eiichi Egami, Justin D. R. Pierel, Fengwu Sun, Armin Rest, David A. Coulter, Michael Engesser, Matthew R. Siebert, Kevin N. Hainline, Benjamin D. Johnson, Andrew J. Bunker, Phillip A. Cargile, Stephane Charlot, Wenlei Chen, Mirko Curti, Shea DeFour-Remy, Daniel J. Eisenstein, Ori D. Fox, Suvi Gezari, Sebastian Gomez, Jacob Jencson, Bhavin A. Joshi, Sanvi Khairnar, Jianwei Lyu, Roberto Maiolino, Takashi J. Moriya, Robert M. Quimby, George H. Rieke, Marcia J. Rieke, Brant Robertson, Melissa Shahbandeh, Louis-Gregory Strolger, Sandro Tacchella, Qinan Wang, Christina C. Williams, Christopher N. A. Willmer, Chris Willott, Yossef Zenati

“…We found 79 SNe: 38 at z < 2, 23 at 2 < z < 3, 8 at 3 < z < 4, 7 at 4 < z < 5, and 3 with undetermined redshifts, where the redshifts are predominantly based on spectroscopic or highly reliable JADES photometric redshifts of the host galaxies. At this depth, the detection rate is ∼1–2 arcmin ^–2 yr ^–1 , demonstrating the power of JWST as an SN discovery machine. …”
Get full text

Chaetoceros muelleri sulfated polysaccharides: chain conformation, physical characteristics, and morphology by Valeria Miranda-Arizmendi, Jorge Marquez-Escalante, Agustin Rascon-Chu, Karla Martínez-Robinson, Francisco Brown-Bojorquez, Elizabeth Carvajal-Millan

“…S=O and C–O–S signals were detected at 1225 and 820 cm−1, respectively, confirming the presence of sulfate in the molecules. …”
Get full text

LincRNA Cox-2 Regulates Lipopolysaccharide-Induced Inflammatory Response of Human Peritoneal Mesothelial Cells via Modulating miR-21/NF-κB Axis by Yaoyao Bian, Lili Yang, Bin Zhang, Wen Li, Sen Wang, Shuling Jiang, Xi Chen, Wenlin Li, Li Zeng

“…The Cox-2 expression in peritoneal adhesion tissues and normal tissues was detected. The human peritoneal mesothelium cells (HPMCs) were treated with lipopolysaccharide (LPS) to induce inflammatory injury. …”
Get full text

Temporal and habitat-specific variations in drivers of aboveground biomass dynamics in a Chinese subtropical forest by Yuxuan Bian, Qi Wu, Rong Zheng, Jiaqin Fu, Jianhua Chen, Xiangcheng Mi, Mingjian Yu, Yunquan Wang, Yunquan Wang, Yunquan Wang

“…In contrast, no statistically significant alterations were detected in the aboveground biomass of mid-hillside and high-ridge habitats. …”
Get full text

A Case of Ileocecal IgG4-Related Sclerosing Mesenteritis Diagnosed by Endoscopic Ultrasound-Guided Fine Needle Aspiration using Forward-Viewing Linear Echoendoscope by Yuichi Takano, Fumitaka Niiya, Takahiro Kobayashi, Eiichi Yamamura, Naotaka Maruoka, Tomoko Norose, Nobuyuki Ohike, Masatsugu Nagahama

“…Pathological finding was an inflammatory fibrous tissue with diffuse lymphoplasmacytic infiltration, with more than 10 IgG4-positive cells detected in a high-power field. Re-examination of a pathology specimen of the maxillary sinus tumor provided by the previous attending physician revealed that the inflammatory tissue had diffuse lymphoplasmacytic infiltration, which were accompanied by storiform fibrosis and obliterative phlebitis. …”
Get full text

The Impact of Amniotic Fluid Interleukin-6, Interleukin-8, and Metalloproteinase-9 on Preterm Labor: A Narrative Review by Theodoros Karampitsakos, Despoina Mavrogianni, Nikolaos Machairiotis, Anastasios Potiris, Periklis Panagopoulos, Sofoklis Stavros, Panos Antsaklis, Peter Drakakis

“…The findings emphasize integrating these biomarkers into diagnostic tools for routine prenatal care, enhancing early detection, risk stratification, and timely interventions to improve maternal and neonatal outcomes.…”
Get full text

Recommendations of the Russian Gastroenterological Association in Diagnosis and Treatment of Gastroesophageal Reflux Disease by V. T. Ivashkin, I. V. Maev, A. S. Trukhmanov, T. L. Lapina, O. A. Storonova, O. V. Zayratyants, O. B. Dronova, Yu. A. Kucheryavyy, S. S. Pirogov, R. G. Sayfutdinov, Yu. P. Uspenskiy, A. A. Sheptulin, D. N. Andreev, D. E. Rumyantseva

“…Esophagogastroduodenoscopy (EGDS) allows detection of reflux esophagitis of various severity and cylindrical epithelial metaplasia of esophagus. …”
Get full text

Simultaneous Determination of 13 Constituents of Radix Polygoni Multiflori in Rat Plasma and Its Application in a Pharmacokinetic Study by Wenhao Cheng, Yinghui Li, Wei Yang, Siyang Wu, Mengmeng Wei, Yang Gao, Chen Kang, Shuofeng Zhang, Yingfei Li

“…The constituents were detected in negative ionization mode using multiple reaction monitoring. …”
Get full text

Android to gynoid fat ratio and its association with functional capacity in male patients with heart failure by Marcelo Rodrigues Dos Santos, Guilherme Wesley Peixoto daFonseca, Letícia Pironato Sherveninas, Francis Ribeiro deSouza, Antônio Carlos Battaglia Filho, Caio Eduardo Novaes, Rosa Maria Rodrigues Pereira, Carlos Eduardo Negrão, Antônio Carlos Pereira Barretto, Maria‐Janieire de Nazaré Nunes Alves

“…A/G ratio > 0.55 was detected in 60 patients. Relative peak VO2 was lower in patients with A/G ratio > 0.55 than in patients with A/G ratio <0.55 (18.7 ± 5.3 vs. 22.5 ± 6.1 mL/kg/min, P < 0.001). …”
Get full text

Nociceptor-localized KCC2 suppresses brachial plexus avulsion-induced neuropathic pain and related central sensitization by Hang Xian, Huan Guo, Yuan-Ying Liu, Sui-Bin Ma, Rui Zhao, Jian-Lei Zhang, Hang Zhang, Rou-Gang Xie, Xu-Cheng Guo, Jie Ren, Sheng-Xi Wu, Ceng Luo, Rui Cong

“…Decreased expression of KCC2 in dorsal root ganglion (DRG) was detected through Western blot and FISH technology after BPA. …”
Get full text

Safety and Effectiveness of BPaL-Based Regimens to Treat Multidrug-Resistant TB: First Experience of an Italian Tuberculosis Referral Hospital by Gina Gualano, Maria Musso, Paola Mencarini, Silvia Mosti, Carlotta Cerva, Pietro Vittozzi, Antonio Mazzarelli, Angela Cannas, Assunta Navarra, Stefania Ianniello, Paolo Faccendini, Fabrizio Palmieri

“…These regimes include bedaquiline (B), pretomanid (P), and linezolid (L) (BPaL), and moxifloxacin if resistance to fluoroquinolones is not detected (BPaLM). Based on the evidence generated by the TB-PRACTECAL and ZeNix randomized controlled trials, BPaL/BPaLM regimens are recommended over the currently recommended longer regimens in patients with MDR-TB or monoresistance to rifampin (RR). …”
Get full text

Interleukin-18 Expression Increases in the Aorta and Plasma of Patients with Acute Aortic Dissection by Haiying Hu, Guangtai Zhang, Huanli Hu, Wenjing Liu, Jixiang Liu, Shuanli Xin, Xiufeng Zhao, Liying Han, Liping Duan, Xinshun Huang, Chao Chang

“…In addition, the IL-18, IL-6, interferon- (IFN-) γ, and IL-18-binding protein (IL-18BP) concentrations in plasma samples collected from the NAD and AD patients were detected. The effects of IL-18 on macrophage differentiation and smooth muscle cell (SMC) apoptosis were investigated in vitro. …”
Get full text

Acidity, sugar, and alcohol contents during the fermentation of Osmanthus-flavored sweet rice wine and microbial community dynamics by Ping Tian, Jiaqiong Wan, Tuo Yin, Li Liu, Hongbing Ren, Hanbing Cai, Xiaozhen Liu, Hanyao Zhang

“…Acidity and total sugars increased with fermentation time, and alcohol was not detected until the end of fermentation. Diversity analysis revealed that the dominant species at the beginning of natural fermentation was A. johnsonii, and R. delemar became the dominant species as natural fermentation progressed. …”
Get full text

Classification Based on the Support Vector Machine for Determining Operational Targets for Controlling Electricity Usage With Conventional Meters: A Case Study of Industrial and Bu... by Galih Arisona, Alief Pascal Taruna, Dwi Irwanto, Arif Bijak Bestari, Wildan Juniawan

“…This research aims to improve the detection of electricity theft through a machine learning-based model utilizing the Support Vector Machine (SVM) classification technique. …”
Get full text

Ginsenosides 20R-Rg3 and Rg5 enriched black ginseng inhibits colorectal cancer tumor growth by activating the Akt/Bax/caspase-3 pathway and modulating gut microbiota in mice by Peng Yu, Weiyin Xu, Yanqi Li, Zhaoyang Xie, Simeng Shao, Jianing Liu, Ying Wang, Long Wang, Hongmei Yang

“…Interestingly, much higher concentrations of rare ginsenosides were detected in this unique BG than those in red ginseng, especially 20R-Rg3 and Rg5, which may contribute to treatment of CRC. …”
Get full text

Tumor characteristics and survival rate of axillary metastatic breast cancer patients: a three decades retrospective cohort study by Seyed Mohamad Sadegh Mousavi-kiasary, Mahdis Bayat, Fereshteh Abbasvandi, Batoul Khoundabi, Fatemeh Mousavi, Atieh Akbari, Maryam Bagherian, Afsoon Zandi, Behnam Honarvar, Mohammad Esmaeil Akbari

“…Regarding the crucial impact of the LN status on the survival landscape of breast cancer patients, accurate detection of the involved one and close screening follow-up of patients with more metastatic LNs during the surgery have a high value.…”
Get full text

Results from the Population-Based Gutenberg Health Study Revealing Four Altered Autoantibodies in Retinal Vein Occlusion Patients by Katharina Bell, Vanessa M. Beutgen, Stefan Nickels, Katrin Lorenz, Yvonne Scheller, Hisham Elbaz, Tunde Peto, Katharina A. Ponto, Andreas Schulz, Philipp S. Wild, Thomas Münzel, Karl J. Lackner, Irene Schmidtmann, Manfred Beutel, Norbert Pfeiffer, Franz H. Grus, Alexander K. Schuster

“…Of the 59 RVO patients, 3 patients (5%) showed glaucomatous optic disc alterations at baseline, whereas no new glaucoma case was detected at 5-year follow-up. Four of the autoantibodies measured (against dermcidin, neurotrophin-3, superoxide dismutase 1, and signal recognition particle 14 kDa protein) were significantly increased in the serum of RVO patients p<0.001. …”
Get full text

Removal of the Tumor Thrombus from the Right Atrium without Extracorporeal Circulation: Emphasis on the Displacement of the Tumor Apex by D. V. Shchukin, V. N. Lesovoy, G. G. Khareba, A. I. Harahatyi, A. V. Maltsev, M. M. Polyakov, R. V. Stetsyshyn, M. P. Kopytsya, P. V. Mozzhakov, O. O. Makovozov

“…Specific complications associated with the access to the right atrium from the abdominal cavity (paresis of the right phrenic nerve, pneumothorax, and mediastinitis) were not detected in any case. The average clamping time of the supradiaphragmatic inferior vena cava (IVC) was 6.3 ± 4.6 min. …”
Get full text