Impact of perineural tumor spread in head and neck adenoid cystic carcinoma for carbon-ion radiotherapy by Atsushi Musha, Nobuteru Kubo, Hidemasa Kawamura, Naoko Okano, Masahiro Onishi, Takeru Ohtaka, Midori Tamura, Osamu Nikkuni, Yuichi Tomidokoro, Satoshi Yokoo, Kazuaki Chikamatsu, Tatsuya Ohno

“…PNTS was evaluated by magnetic resonance imaging for detecting extratumoral extension to peritumoral nerves. …”
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Profiling of Somatic Mutations in Phaeochromocytoma and Paraganglioma by Targeted Next Generation Sequencing Analysis by Andrea Luchetti, Diana Walsh, Fay Rodger, Graeme Clark, Tom Martin, Richard Irving, Mario Sanna, Masahiro Yao, Mercedes Robledo, Hartmut P. H. Neumann, Emma R. Woodward, Farida Latif, Stephen Abbs, Howard Martin, Eamonn R. Maher

“…At least 12 genes (FH, HIF2A, MAX, NF1, RET, SDHA, SDHB, SDHC, SDHD, SDHAF2, TMEM127, and VHL) have been implicated in inherited predisposition to phaeochromocytoma (PCC), paraganglioma (PGL), or head and neck paraganglioma (HNPGL) and a germline mutation may be detected in more than 30% of cases. Knowledge of somatic mutations contributing to PCC/PGL/HNPGL pathogenesis has received less attention though mutations in HRAS, HIF2A, NF1, RET, and VHL have been reported. …”
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Noninvasive hemodynamic assessment of type 2 diabetes mellitus using four-dimensional flow magnetic resonance imaging by Di Wu, Jiachen Ji, Yuancheng Wang, Shujun Zhang, Hong Ge, Mingzhu Fu, Yunduo Li, Shenghong Ju, Rui Li

“…This study aimed to investigate early hemodynamic changes in patients with T2DM and evaluated the efficacy of Four-Dimensional Flow Magnetic Resonance Imaging (4D Flow MRI) in detecting and diagnosing T2DM and DN. Methods: The abdominal 4D Flow MRI data from 23 patients with T2DM and 23 healthy volunteers were collected and validated for subsequent analysis. …”
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Causal association between non-thyroidal autoimmune diseases and Graves' ophthalmopathy: A mendelian randomization study by Lan Ma, Xue Jiang, Zhijia Hou, Dongmei Li

“…MR-Egger regression was used to evaluate horizontal pleiotropy and MR pleiotropy residual sum and outlier (MR-PRESSO) test was used to detect the outliers. Results: For non-thyroidal ADs, the forward MR results using the IVM method showed that T1D (OR ​= ​1.259, 95%CI 1.026–1.5465; P ​= ​0.028) and SLE (OR ​= ​1.807, 95%CI 1.229–2.655; P ​= ​0.003) were correlated with the risk of GO at the genetic level, while there was no evidence showing that IBD, MS, PV and RA were correlated with GO. …”
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Effects of Mulch Type, Plant Cultivar, and Insecticide Use on Sweet Potato Whitefly Population in Chili Pepper by Andi Nasruddin, Nurariaty Agus, Alam Saubil, Jumardi Jumardi, Burhanuddin Rasyid, Andry Siriniang, Andi Dirham Nasruddin, Firdaus Firdaus, Ahwiyah Ekawaty Said

“…Bara was more resistant than Bhaskara against B. tabaci in the field; however, in the no-choice trial, no significant difference was detected between both cultivars. Insecticide applications twice per week and once per week were equally effective in controlling the whitefly on the susceptible cultivar (Bhaskara). …”
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Targeted genome modifcation in protoplasts of a highly regenerable Siberian barley cultivar using RNA-guided Cas9 endonuclease by S. V. Gerasimova, A. M. Korotkova, C. Hertig, S. Hiekel, R. Hofe, N. Budhagatapalli, I. Otto, G. Hensel, V. K. Shumny, A. V. Kochetov, J. Kumlehn, E. K. Khlestkina

“…Deep-sequencing of amplicons obtained from protoplast genomic DNA revealed that 6 to 22 percent of the target sites were mutated. The detected modifcations comprised deletions in all three target sites and of various sizes, whereas insertions were observed in only one of the target genes (Vrs1) and were confned to the size of 1 nucleotide. …”
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Mycotoxicological monitoring. Part 1. Complete mixed feed for pigs and poultry (2009–2018) by G. P. Kononenko, A. A. Burkin, Ye. V. Zotova

“…Evidence for a wide occurrence of emodin known as “diarrheic factor” as well as for sporadic increase in mixed feed contamination with alternariol, citrinin, mycophenolic acid, mycotoxins having the highly dangerous toxic impact and long-term adverse effects, was detected for the first time. These data confirmed the need for their inclusion into the regulated group of substances significant for public health. …”
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SVR model and OLCI images reveal a declining trend in phycocyanin levels in typical lakes across Northeast China by Changchun Song, Yipei Xu, Chong Fang, Chi Zhang, Zhuohang Xin, Zhihong Liu

“…Phycocyanin (PC), a distinctive pigment found in cyanobacteria, plays a pivotal role in detecting and predicting harmful cyanobacterial blooms. …”
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Development of a novel strategy for the quantification of ultra-trace impurity elements in high-purity magnesium using inductively coupled plasma tandem mass spectrometry by Liang Fu, Guangsheng Huang, Yaobo Hu, Xianhua Chen, Jingfeng Wang, Fusheng Pan

“…The results indicated that the limits of detection (LOD) were in the range of 0.02–18.5 ng L−1; the LODs of the challenging non-metallic elements Si and S were 18.5 and 12.2 ng L−1, respectively; and the LODs of all the other analytes were less than 10 ng L−1. …”
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WALLABY Pilot Survey: Star Formation Enhancement and Suppression in Gas-rich Galaxy Pairs by Qifeng Huang, Jing Wang, Xuchen Lin, Se-Heon Oh, Xinkai Chen, B. Catinella, N. Deg, H. Dénes, B. -Q. For, B. S. Koribalski, K. Lee-Waddell, J. Rhee, A. X. Shen, Li Shao, K. Spekkens, L. Staveley-Smith, T. Westmeier, O. I. Wong, A. Bosma

“…Here, we investigate the SFR enhancement of gas-rich galaxy pairs detected by the Widefield ASKAP L -band Legacy All-sky Blind surveY. …”
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Integrated Machine Learning Approaches for Landslide Susceptibility Mapping Along the Pakistan–China Karakoram Highway by Mohib Ullah, Haijun Qiu, Wenchao Huangfu, Dongdong Yang, Yingdong Wei, Bingzhe Tang

“…This study identifies approximately 20.70% of the area as from high to very high risk, with the SE model excelling in detecting high-risk zones. Key factors influencing landslide susceptibility showed slight variations across the models, while multicollinearity among variables remained minimal. …”
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Therapeutic Effects of GDF6-Overexpressing Mesenchymal Stem Cells through Upregulation of the GDF15/SIRT1 Axis in Age-Related Hearing Loss by Jiali Liu, Haisen Peng, Yuehui Liu, Chunhua Li, Wen Xie

“…Flow cytometry and immunofluorescence assays were performed for the detection of apoptosis and autophagy, respectively. …”
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DMMR status and synchronous lesions predicts metachronous lesions after curative resection for rectal cancer by Xijie Chen, Xijie Chen, Xijie Chen, Junguo Chen, Junguo Chen, Junguo Chen, Liang Xu, Liang Xu, Dezheng Lin, Dezheng Lin, Dezheng Lin, Xiaoling Hong, Xiaoling Hong, Xiaoling Hong, Junsheng Peng, Junsheng Peng, Junsheng Peng, Xiaowen He, Xiaowen He, Xiaowen He, Jiancong Hu, Jiancong Hu, Jiancong Hu

“…Univariable and multivariable analysis showed dMMR status, synchronous adenomas/polyps, surveillance time > 3, and longer surveillance period patients were significant risk factors for development of metachronous lesions; in subgroup analysis, we also found that among rectal cancer patients with synchronous adenomas, adenomas located in the left colon and rectum, and longer surveillance period were independent risk factors for detecting metachronous adenomas.ConclusionsThis study underscored the importance of extended follow-up protocols and targeted surveillance for identifying and managing metachronous lesions in dMMR rectal cancer patients, especially with synchronous adenomas. …”
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A novel technique of cryodenervation for murine vagus nerve: implications for acute lung inflammation by Di Wu, Ximing Liao, Jing Gao, Kun Wang, Wujian Xu, Feilong Wang, Zhixian Jin, Dandan Wu, Qiang Li, Wei Gao

“…Result We demonstrated that VSCD was able to induce a reliable and stable blockade of innervation, but reversible structural damage of mouse vagus nerve without detectable toxicity to lung tissues. Cholinergic parasympathetic nerve in the mouse lung coming from vagus nerve was activated at the initial stage (1 week) after VSCD, and blocked 3 weeks later. …”
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High-time-cadence Spectroscopy and Photometry of Stellar Flares on M dwarf YZ Canis Minoris with the Seimei Telescope and TESS. I. Discovery of Rapid and Short-duration Prominence... by Yuto Kajikiya, Kosuke Namekata, Yuta Notsu, Hiroyuki Maehara, Bunei Sato, Daisaku Nogami

“…We conducted spectroscopic monitoring observations of the active M dwarf YZ Canis Minoris with an ∼1 minute time cadence using the Seimei telescope, simultaneously with the optical photometric observations by Transiting Exoplanet Survey Satellite. We detected 27 H α flares with H α energies ranging from 1.7 × 10 ^29 to 3.8 × 10 ^32 erg and durations from 8 to 319 minutes. …”
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Association of Maternal Diabetes Mellitus and Polymorphisms of the NKX2.5 Gene in Children with Congenital Heart Disease: A Single Centre-Based Case-Control Study by Mingyi Zhao, Jingyi Diao, Peng Huang, Jinqi Li, Yihuan Li, Yang Yang, Liu Luo, Senmao Zhang, Letao Chen, Tingting Wang, Ping Zhu, Jiabi Qin

“…We collected the mothers’ information by questionnaire and detected children’s NKX2.5 variants with a MassARRAY system. …”
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Morphological Neuroimaging Biomarkers for Tinnitus: Evidence Obtained by Applying Machine Learning by Yawen Liu, Haijun Niu, Jianming Zhu, Pengfei Zhao, Hongxia Yin, Heyu Ding, Shusheng Gong, Zhenghan Yang, Han Lv, Zhenchang Wang

“…According to previous studies, many neuroanatomical alterations have been detected in patients with tinnitus. However, the results of these studies have been inconsistent. …”
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Syphilis among Female Sex Workers: Results of Point-of-Care Screening during a Cross-Sectional Behavioral Survey in Burkina Faso, West Africa by Henri Gautier Ouedraogo, Ivlabehire Bertrand Meda, Issaka Zongo, Odette Ky-Zerbo, Ashley Grosso, Benoit Cesaire Samadoulougou, Grissoum Tarnagda, Kadari Cisse, Apoline Sondo, Nongoba Sawadogo, Yves Traoré, Nicolas Barro, Stefan Baral, Seni Kouanda

“…The syphilis serological markers were detected in 5.6% (95% CI: 4.4–7.2) of the participants whereas active syphilis was seen in 1.4% (95% CI: 0.9–2.4). …”
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Pearls on a String: Dark and Bright Galaxies on a Strikingly Straight and Narrow Filament by M. Arabsalmani, S. Roychowdhury, B. Schneider, V. Springel, E. Le Floc’h, F. Bournaud, A. Burkert, J.-C. Cuillandre, P.-A. Duc, E. Emsellem, D. Galárraga-Espinosa, E. Pian, F. Renaud, M. A. Zwaan

“…We study the cold H i gas in a 1.3 Mpc section of the filament through H i 21 cm emission line observations and detect 11 H i sources, many more than expected from the H i mass function in a similar volume. …”
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Case report: Deciphering the clinical significance of a novel partial BRCA1 exon 10 duplication in a patient with triple-negative breast cancer by Alice Faversani, Debora Manuelli, Davide Barteselli, Giulia Melloni, Carlo Santaniello, Luigi Corsaro, Luigi Corsaro, Davide Sacco, Davide Sacco, Davide Clerici, Laura Gargiulo, Fulvio Ferrara, Lucy Costantino

“…Other investigations, such as the detection of breakpoints by RNA analysis, are often essential to classify the identified alteration. …”
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