Aqueous humor metabolomic profiling identifies a distinct signature in pseudoexfoliation syndrome by Arturs Zemitis, Arturs Zemitis, Juris Vanags, Juris Vanags, Theresa Schiemer, Theresa Schiemer, Kristaps Klavins, Kristaps Klavins, Guna Laganovska, Guna Laganovska

“…Intraocular fluid samples from these patients were analyzed using targeted metabolite analysis, performed through HILIC liquid chromatography coupled with mass spectrometry detection.ResultsThe aqueous humor of PEXS patients contains statistically significant higher levels of cystine (p < 0.001), citrulline (p < 0.001), phenylalanine (p = 0.041), tyrosine (p = 0.025), serine (p = 0.030), arginine (p = 0.017), lactic acid (p = 0.055), tryptophan (p = 0.055), and creatinine (p = 0.022). …”
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Supra-Acetabular Brown Tumor due to Primary Hyperparathyroidism Associated with Chronic Renal Failure by Rosaria M. Ruggeri, Emanuele Calamoneri, Antonia Russo, Alessandro Sindoni, Baldassarre Mondello, Maurizio Monaco, Michele A. Rosa, Sergio Baldari, Salvatore Benvenga, Alfredo Campennì, Francesco Trimarchi

“…Physical examination revealed deep pain in the iliac region and severe restriction of the right hip's articular function in the maximum degrees of range of motion. X-rays and CT scan detected an osteolytic and expansive lesion of the right supra-acetabular region with structural reabsorption of the right iliac wing. 99mTc-MDP whole-body bone scan showed an abnormal uptake in the right iliac region. …”
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Kinetic and Photochemical Disequilibrium in the Potentially Carbon-rich Atmosphere of the Warm Jupiter WASP-69 b by Nidhi Bangera, Christiane Helling, Gloria Guilluy, Patricio Cubillos, Luca Fossati, Paolo Giacobbe, Paul Rimmer, Daniel Kitzmann

“…This study investigates the impact of vertical diffusion and photochemistry on its atmospheric composition, with a focus on the detected species plus HCN and CO _2 , to constrain the atmospheric C/O ratio. …”
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Diversity of the Amoebozoa and Ciliophora Groups in Non-Human Primates Kept Ex Situ and in Their Handlers in Different Institutions in Brazil by Laís Dib, Breno da Silva, Lais Correa, Alcides Pissinatti, Silvia Moreira, Maria Clotilde Tavares, Rodrigo Teixeira, André Luíz da Costa, José Augusto Muniz, Amauri Junglos, Zelinda Maria Hirano, Aline Dada, Sidnei da Silva, Maria Regina Amendoeira, Alynne Barbosa

“…Greater protist diversity occurred in northern and southeastern regions, with <i>E. histolytica</i> and <i>B. coli</i> detected in endangered species, such as <i>Saguinus bicolor</i> and <i>Alouatta guariba</i>. …”
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Cryptic species and hybridisation in corals: challenges and opportunities for conservation and restoration by Riginos, Cynthia, Popovic, Iva, Meziere, Zoe, Garcia, Vhon, Byrne, Ilha, Howitt, Samantha M., Ishida, Hisatake, Bairos-Novak, Kevin, Humanes, Adriana, Scharfenstein, Hugo, Richards, Thomas, Briggs, Ethan, Clark, Vanessa, Lei, Chuan, Khan, Mariam, Prata, Katharine E.

“…Using reproducible criteria to detect distinct genetic groups that are sympatric, we find that 68% of nominal species represented in population genomic studies show evidence for comprising partially reproductively isolated groups and that these distinct groups are often linked by gene flow. …”
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Alcohol promotes CPT1A-induced lipid metabolism disorder to sentinel-regulate acute pancreatitis by Zenghui Li, Xinghui Li, Hui Jiang, Jingdong Li, Bin Xiao, Yong Chen, Shunhai Jian, Mei Zeng, Xiaoming Zhang

“…The metabolite levels in the pancreatic tissue, serum of rats and serum of persons with a history of alcohol consumption were detected by LC‒MS/MS. In the present study the impact of etomoxir (a carnitine palmitoyl-transferase 1A-specific inhibitor) treatment on AR42J cells treated with alcohol and the effect of etomoxir injection on the inflammatory response in an alcohol + cerulein-induced AAP rat model was evaluated. …”
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Sodium arsenite induces islets β-cells apoptosis and dysfunction via SET-Rac1-mediated cytoskeleton disturbance by Tianming Qiu, Yu Zhi, Jingyuan Zhang, Ningning Wang, Xiaofeng Yao, Guang Yang, Liping Jiang, Li Lv, Xiance Sun

“…Notably, overexpression of SET or inhibition of Rac1 substantially mitigated the apoptosis of islet β-cells and ameliorated the impaired insulin secretion (increased from 0.1 ng/ml to 0.2 ng/ml) caused by NaAsO2 exposure. In addition, we detected cytoskeletal disorganization following NaAsO2 treatment, characterized by elevated Cofilin-1 protein expression (approximately 2.5-fold) and disrupted cytoskeleton arrangement. …”
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Colonic Oxidative and Mitochondrial Function in Parkinson’s Disease and Idiopathic REM Sleep Behavior Disorder by C. Morén, Í. González-Casacuberta, J. Navarro-Otano, D. Juárez-Flores, D. Vilas, G. Garrabou, J. C. Milisenda, C. Pont-Sunyer, M. Catalán-García, M. Guitart-Mampel, E. Tobías, F. Cardellach, F. Valldeoriola, A. Iranzo, E. Tolosa

“…Antioxidant enzymes SOD2 (iRBD: 2.30±0.92, PD: 1.48±0.39, and controls: 1.09±0.318) and Gpx1 (iRBD 0.29±0.12, PD: 0.56±0.33, and controls: 0.38±0.16) did not show significant differences between groups. CAT was only detected in 2 controls and 1 iRBD subject. One iRBD patient presented a single mtDNA deletion.…”
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Early Transcriptional Changes Induced by Wnt/β-Catenin Signaling in Hippocampal Neurons by Eduardo Pérez-Palma, Víctor Andrade, Mario O. Caracci, Bernabé I. Bustos, Camilo Villaman, Matías A. Medina, Miguel E. Ávila, Giorgia D. Ugarte, Giancarlo V. De Ferrari

“…We also studied molecular networks enriched upon Wnt3a activation and detected three highly significant expression modules involved in glycerolipid metabolic process (GO:0046486, p-adjusted = 4.5 × 10−19), learning or memory (GO:0007611, p-adjusted = 4.0 × 10−5), and neurotransmitter secretion (GO:0007269, p-adjusted = 5.3 × 10−12). …”
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Investigation of <i>Atraphaxis virgata</i>, an Unexplored Medicinal Plant Rich in Flavonoids, as a Functional Material by Soeun Shin, Seunghee Kim, Jeongho Lee, Hyerim Son, Jin-Hyub Paik, Nadezhda Gennadievna Gemejiyeva, Zhanat Zhumabekovna Karzhaubekova, Taek Lee, Hah Young Yoo

“…Furthermore, GC-MS analysis detected nine compounds (e.g., lup-20(29)-en-3-one and decane) in the extracts, which were reported to have various biological activities. …”
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Moroccan Monofloral Bee Pollen: Botanical Origin, Physicochemical Characterization, and Antioxidant Activities by El Ghouizi Asmae, El Menyiy Nawal, Meryem Bakour, Badiaa Lyoussi

“…Potassium and magnesium were the most abundant minerals in bee pollen samples; heavy metals were not detected except for two samples (P5 and P6) where a very small amount of lead was found. …”
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Monocyte to High‐Density Lipoprotein Ratio Is Associated With Carotid Plaque: A Retrospective Cohort Study by Shuang Liu, Xinlei Miao, Manling Hu, Ziping Song, Xiaoling Xie, Yuting Sun, Meng Li, Guimin Tang, Song Leng

“…The assessment and management of MHR is helpful for the early detection of patients with CP and the primary prevention of cardiovascular diseases.…”
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Autophagy inhibitor 3-methyladenine mitigates the severity of colitis in aged mice by inhibiting autophagy by Ailing Liu, Hongying Wang, Hong Lv, Hong Yang, Yue Li, Jiaming Qian

“…The autophagy activity was detected by the protein expressions of LC3B-II, p62 and ATG5 by western blot and immunohistochemistry. …”
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An improved ShuffleNetV2 method based on ensemble self-distillation for tomato leaf diseases recognition by Shuiping Ni, Yue Jia, Mingfu Zhu, Mingfu Zhu, Yizhe Zhang, Wendi Wang, Shangxin Liu, Yawei Chen

“…Among lightweight models, it has the smallest parameter count and the highest recognition accuracy.DiscussionThe results demonstrate that the optimized ShuffleNetV2 is more suitable for deployment on edge devices for real-time tomato disease detection. Additionally, multiple shallow models achieve varying degrees of compression for ShuffleNetV2, providing flexibility for model deployment.…”
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Arsenic and Heavy Metals in Vietnamese Rice: Assessment of Human Exposure to These Elements through Rice Consumption by Dinh Binh Chu, Hung Tuan Duong, Minh Thi Nguyet Luu, Hong-An Vu-Thi, Bich-Thuy Ly, Vu Duc Loi

“…Mercury, a highly toxic element, has been only found in rice samples collected in the mining activity zone (frequency detection 14.5% of total samples). The experimental results indicated that the heavy metals and arsenic found in rice collected from mining activity zone were higher than those in rice harvested from normal cultivated areas like the Red River Delta. …”
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High hemolytic activity in Staphylococcus aureus t1081/ST45 due to increased hla protein production and potential RNAIII-independent regulation by Yu-Tzu Lin, Ngoc-Niem Bui, Yu-Syuan Cheng, Cheng-Wen Lin, Chun-Li Lee, Tai-Fen Lee, Po-Ren Hsueh

“…No significant differences in hla sequences, upstream regulatory regions, or gene expression levels were detected between the two groups. The expression of the transcriptional regulators mgrA and saeR was also similar between the two groups. …”
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Diversity of new Russian bread wheat cultivars according to leaf rust resistance genes by E. I. Gultyaeva, E. L. Shaydayuk, V. V. Veselova, R. E. Smirnova, E. V. Zuev, A. G. Khakimova, O. P. Mitrofanova

“…Markers of identifiable genes were not detected in cv. ‘Sharm’, highly resistant to leaf rust. …”
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Advantages of using T1-mapping in cardiac magnetic resonance imaging in patients with acromegaly by Alina A. Almaskhanova, Konstantin V. Melkozerov, Elena G. Przhiyalkovskaya, Natalia V. Tarbaeva, Anastasya Y. Korneluk, Raisa S. Kosharnaia, Victor Y. Kalashnikov, Zhanna E. Belaya, Galina A. Mel'nichenko, Natalia G. Mokrysheva

“…All patients underwent standard medical examinations, including hormonal blood tests, electrocardiograms, echocardiography, Holter monitoring electrocardiograms and magnetic resonance imaging (MRI) of the heart with gadolinium contrast, additionally 48 patients underwent T1-mapping, which is an MRI method that allows the detection of diffuse changes by measuring the values of myocardial relaxation time – T1. …”
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The clinical value of Serum hyaluronic acid, procollagen III, N-terminal propeptide levels sST2 and cfDNA in predicting the myocardial damage in children with severe pneumonia by Haoran Jia, Ye Liu, Tingting Zhao, Dexing Wang, Meng Du, Weiwei Wang

“…Biomarker levels (hyaluronic acid, procollagen III, N-terminal propeptide levels, sST2, and cfDNA) were detected through biochemical analysis, and clinical outcomes were compared between the two groups. …”
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The Analysis of the Fetal Abdominal Wall and Gastrointestinal Tract Abnormalities in a Single Tertiary Center by Gokhan Bolluk, Suleyman Cemil Oglak, Merih Cetinkaya, Isil Turan Bakirci, Oyhan Demirali, Mehmet Cok, Handan Turhan Karakus, Yasin Onur, Emine Zeynep Yilmaz

“… OBJECTIVE: We aimed to evaluate the fetuses with gastrointestinal anomalies and anterior abdominal wall defects detected in the prenatal period in our clinic and to analyze their perinatal outcomes. …”
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