Spectrophotometric and computational characterization of charge transfer complex of selumetinib with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone and its utilization in developing an... by Sarah Alrubia, Wafa A. AlShehri, Awwad A. Radwan, Nourah Z. Alzoman, Ibrahim A. Darwish

“…The assay was linear in SEL’ concentrations ranged from 10 to 200 µg/well, with limits of detection and quantitation of 4.1 and 12.5 µg/well, respectively. …”
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Avirulence depletion assay: Combining R gene-mediated selection with bulk sequencing for rapid avirulence gene identification in wheat powdery mildew. by Lukas Kunz, Jigisha Jigisha, Fabrizio Menardo, Alexandros G Sotiropoulos, Helen Zbinden, Shenghao Zou, Dingzhong Tang, Ralph Hückelhoven, Beat Keller, Marion C Müller

“…Wheat resistance breeding frequently relies on the use of resistance (R) genes that encode diverse immune receptors which detect specific avirulence (AVR) effectors and subsequently induce an immune response. …”
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Electroacupuncture Therapy Effectively Protects the Rat Brain after Intracerebral Hemorrhage by Li Huang, Xuehui Fan, Yao Chen, Heng Lin, Xiaoqian Jiang, Chaoxian Yang

“…The expression levels of the CD68, GALC, Arg-1, iNOS, NR2A, Glu2R, AQP4, MAP2, GFAP, AQP9, Bcl-2, Bax, and Glu proteins around the hematoma were detected via immunohistochemistry staining. Western blot was used to analyze the levels of the AQP4, AQP9, Bax, Bcl-2, iNOS, and Arg-1 proteins. …”
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Supporting Smart Manufacturing in the Space Industry: A Case Study by Ala Arman, Andrea Lombardo, Flavia Monti, Massimo Mecella

“…This facilitates comprehensive analysis of the entire MAIT process, supporting trend detection, anomaly identification, and areas for improvement to facilitate data‐driven decision‐making. …”
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Interferon (IFN)-gamma (γ) inducible protein 10 (IP-10) in the diagnosis of latent and active tuberculosis in Bacille Calmette Guerin (BCG)-vaccinated pediatric population. by Magdalena Druszczynska, Michał Seweryn, Sebastian Wawrocki, Anna Pankowska, Anastasiia Kulbachko, Magdalena Jurczak, Magdalena Kowalewska-Pietrzak

“…<h4>Background</h4>Accurate diagnosis of tuberculosis (TB) in children continues to be challenging, primarily due to the low bacterial load characteristic of the disease and the obstacles in collecting sputum samples. Furthermore, detecting cases of latent Mycobacterium tuberculosis (M.tb) infection (LTBI) that have a high risk of progressing to active TB disease remains a significant diagnostic hurdle.…”
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Malyngamide F Possesses Anti-Inflammatory and Antinociceptive Activity in Rat Models of Inflammation by Zhuocheng Li, Lei Zhang, Zhichao Zhao

“…Levels of TNF-α, PGE-2, and IL-6 were detected by enzyme-linked immunosorbent assay (ELISA). …”
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Activation of FGD5-AS1 Promotes Progression of Cervical Cancer through Regulating BST2 to Inhibit Macrophage M1 Polarization by Guokun Liu, Xuan Du, Li Xiao, Qing Zeng, QianLing Liu

“…The level of FGD5-AS1 and BST2 was detected by qRT-PCR in cervical cancer cells. FGD5-AS1 and BST2 expression was significantly upregulated in cervical cancer cells. …”
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Evaluation of macula ganglion cell analysis and retinal nerve fiber layer thickness in preperimetric glaucoma, early stage glaucoma and healthy individuals by Ozlem AKTAS  OZALTUN, Ozlem GURBUZ  KOZ, Ahmet Alper YARANGUMELI

“…In the wide-field SuperPixel map, the frequency of glaucomatous defect detection was higher in the EG group than in the PPG group (p < 0.05). …”
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The virome composition of respiratory tract changes in school-aged children with Mycoplasma pneumoniae infection by Dianqi Zhang, Yang Cao, Biao Dai, Teng Zhang, Xing Jin, Qingyue Lan, Chaoying Qian, Yumin He, Yi Jiang

“…In addition, some new viruses, such as rhinovirus, respirovirus, dependoparvovirus, and a novel gemykibvirus, were also detected in the BALF of the disease cohort. Conclusions This cross-sectional research highlighted the respiratory virome characteristics of school-aged children with MPI after the COVID-19 outbreak and provided important epidemiological information. …”
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Zebularine Promotes Hepatic Differentiation of Rabbit Bone Marrow Mesenchymal Stem Cells by Interfering with p38 MAPK Signaling by Yong-Heng Luo, Juan Chen, En-Hua Xiao, Qiu-Yun Li, Yong-Mei Luo

“…BMMSCs were treated with zebularine at concentrations of 10, 20, 50, and 100 μM in the presence of hepatocyte growth factor; changes in the levels of hepatic-specific alpha-fetoprotein and albumin were detected and determined by RT-PCR, WB, and immunofluorescence staining. …”
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Addressing the rising colorectal cancer burden in the older adult: examining modifiable risk and protective factors for comprehensive prevention strategies by Ke‐Jie He, Zhejun Liu, Guoyu Gong

“…These regional differences are likely attributable to variations in healthcare systems, access to screening and early detection programs, as well as differences in lifestyle behaviors and risk factor prevalence.ConclusionThe strong association between high BMI and colorectal cancer risk, particularly in the older adult population and among men, emphasizes the importance of comprehensive obesity management strategies as part of comprehensive cancer control efforts. …”
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An In-Depth Study of Personalized Anesthesia Management Models in Gastrointestinal Endoscopy Based on Multimodal Deep Learning by Hanqi Shi, Hongyu Wang, Xibing Ding, Zheng Dang

“…This model was designed to enhance anesthesia management efficiency and disease detection rates. In collaboration with the Department of Anesthesiology at Renji Hospital, which is affiliated with the Shanghai Jiao Tong University School of Medicine, data pertaining to anesthesia were collected from 398 patients, who were undergoing gastrointestinal endoscopy. …”
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Characterizing Antimicrobial Effects of Radiation and Antibiotic Interactions on <i>Staphylococcus aureus</i> and <i>Escherichia coli</i> Using MALDI-TOF MS by Ali Haider, Renáta Homlok, Csilla Mohácsiné Farkas, Tamás Kocsis

“…The findings highlight MALDI-TOF MS as a valuable tool in detecting proteomic biomarkers linked to bacterial resistance and stress adaptation.…”
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Changes in the Nutrient Composition of Barley Grain (Hordeum vulgare L.) and of Morphological Fractions of Sprouts by Luis T. Ortiz, Susana Velasco, Jesús Treviño, Beatriz Jiménez, Almudena Rebolé

“…Regarding fatty acids, an increase in the relative concentration of C18 : 0 and C18:3n-3 and a decrease in that of C18:1n-9 were detected. Partitioning of sprouted barley into three morphological component fractions showed that the residual structures of sprouted grains plus unsprouted grain fraction made up 82.9% and 93.6% of sprout biomass, on fresh and DM basis, respectively, and the remainder was provided by the root fraction, 10.3% and 3.2%, respectively, and by the green shoot fraction, 6.8% and 3.1%, respectively. …”
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The impact of type 2 diabetes on left ventricular function in hypertensive patients: a three-dimensional speckle-tracking imaging study by Yang Qingmei, Chen Xiaoyan, Fang Jianxiu

“…Furthermore, linear mixed-model analysis revealed that LV GCS (β = 1.20, 95% CI: 0.38–2.01, p = 0.004) and GRS (β = −2.82, 95% CI: −4.97–0.68, p = 0.010) deteriorated over the 12-month period.ConclusionsT2DM exacerbates the decline in LV global and regional strains in patients with hypertension, and 3D-STI may be a valuable tool for detecting these asymptomatic preclinical abnormalities.…”
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AI enabled, mobile soil pH classification with colorimetric paper sensors for sustainable agriculture. by Ademir Ferreira da Silva, Ricardo Luis Ohta, Jaione Tirapu Azpiroz, Matheus Esteves Ferreira, Daniel Vitor Marçal, André Botelho, Tulio Coppola, Allysson Flavio Melo de Oliveira, Murilo Bettarello, Lauren Schneider, Rodrigo Vilaça, Noorunisha Abdool, Vanderlei Junior, Wellington Furlaneti, Pedro Augusto Malanga, Mathias Steiner

“…By performing on-the-spot analyses using the mobile system in the field, a 9-fold increase of spatial resolution reveals pH-variations not detectable in the standard compound mapping mode of lab analysis. …”
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Hepatitis E virus infection among blood donors in Hangzhou by DU Ziyun, DENG Wenjun, WU Danxiao, LIU Jinhui, DONG Jie

“…Enzyme-linked immunosorbent assay (ELISA) was used to detect anti-HEV IgM, anti-HEV IgG and HEV-Ag. The Fisher test and Chi-square test were used to evaluate the difference in the reactivity rates of anti-HEV IgM and anti-HEV IgG among different levels of ALT. …”
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The Tasmanian Estuary Perch Population—A Threatened Species? by Jonah L. Yick, Bryan Van Wyk, James Haddy

“…Although three strong age classes were detected (five, eight and twenty-three years), numerous weak and missing cohorts were apparent. …”
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Retinal Thickness Asymmetry in Highly Myopic Eyes with Early Stage of Normal-Tension Glaucoma by Pei-Wen Lin, Hsueh-Wen Chang, Yi-Chieh Poon

“…Asymmetry analysis of retinal thickness can be an adjunctive tool for the early detection of HM NTG.…”
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Features of the Modern Protectionism of the US and the EU towards Russia by A. A. Sidorov

“…The mechanism can be considered an attempt to make up for the EU’s lack of natural competitive advantages in mineral raw materials and to impose its vision of economic policy goals on the rest of the world.In conclusion, the author highlights features of American and European protectionism towards Russia – active employment of the role of the state in the economy factor as well as environmental factor as pretexts for introducing or tightening restrictive measures.The main ways of Russia’s response to new challenges can be the use of the WTO platform in cooperation with other countries, the search for new economic levers in relations with the partners (including application of trade defence measures), the detection of possible market distortions in the EU and the US for possible use in EAEU investigations.…”
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