A Study of the Star Clusters’ Population in the Giant Molecular Cloud G174+2.5 by Tatyana A. Permyakova, Giovanni Carraro, Anton F. Seleznev, Andrej M. Sobolev, Dmitry A. Ladeyschikov, Maria S. Kirsanova

“…First, we recover all the known embedded clusters and candidate clusters in the region using surface density maps. Then, for the detected clusters, we determine their general parameters: the center positions, radii, number of stars, and reddening. …”
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Flow Cytometric Analysis of T, B, and NK Cells Antigens in Patients with Mycosis Fungoides by Serkan Yazıcı, Emel Bülbül Başkan, Ferah Budak, Barbaros Oral, Şaduman Balaban Adim, Zübeyde Ceylan Kalin, Güven Özkaya, Kenan Aydoğan, Hayriye Saricaoğlu, Şükran Tunali

“…Fluorescent labeled monoclonal antibodies were used to detect cell surface antigens: T cells (CD3+, CD4+, CD8+, TCRαβ+, TCRγδ+, CD7+, CD4+CD7+, CD4+CD7−, and CD71+), B cells (HLA-DR+, CD19+, and HLA-DR+CD19+), NKT cells (CD3+CD16+CD56+), and NK cells (CD3−CD16+CD56+). …”
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Predicting Neoplastic Gallbladder Polyps: The Role of Current Surgical Indications and Preoperative Images by Ik Hyun Jo, Chang Nyol Paik, Hong Geun Ahn, Dong Do You, Jae Hyun Han, Hyun A Kim

“…This study examined the accuracy of surgical indications commonly used in clinical practice for detecting neoplastic polyps and investigated further clues for predicting neoplastic polyps. …”
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Application of Factorial and Doehlert Designs for the Optimization of the Simultaneous Separation and Determination of Antimigraine Drugs in Pharmaceutical Formulations by RP-HPLC-... by Sami Jebali, Chaouki Belgacem, Mohamed Radhouen Louhaichi, Senda Bahri, Latifa Latrous El Atarche

“…The optimum separation was achieved by means of a Waters XBridge C18 column (250 mm × 4.6 mm, 5 μm) with a mobile phase consisting of acetonitrile and a 10 mM sodium perchlorate buffer (38 : 62, v/v) at a flow rate of 1.0 mL·min−1 and UV detection at 220 nm. The selectivity, method linearity, accuracy, and precision were examined as part of the method validation. …”
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Riverine microplastic discharge along the southern Black Sea coast of Türkiye by Yahya Terzi, Rafet Çağrı Öztürk, Ahmet Raif Eryaşar, İlhan Yandi, Ahmet Şahin, Fatih Yılmaz, Kenan Gedik, Sedat Gündoğdu

“…While no significant differences in MP characteristics were detected between basins (NMDS and ANOSIM), this study emphasizes rivers as major pathways for MP pollution in the Black Sea. …”
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Evaluation of Antibiotic Resistance and Biofilm Production among Clinical Strain Isolated from Medical Devices by Veronica Folliero, Gianluigi Franci, Federica Dell’Annunziata, Rosa Giugliano, Francesco Foglia, Rossella Sperlongano, Anna De Filippis, Emiliana Finamore, Massimiliano Galdiero

“…The present study aimed to detect biofilm formation among MD bacterial isolates and to explore their antibiotic resistance profile. …”
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Diabetic Distal Symmetrical Polyneuropathy: Correlation of Clinical, Laboratory, and Electrophysiologic Studies in Patients with Type 2 Diabetes Mellitus by Yi-Ching Weng, Sung-Sheng Tsai, Rong-Kuo Lyu, Chun-Che Chu, Long-Sun Ro, Ming-Feng Liao, Hong-Shiu Chang, Chiung-Mei Chen, Jawl-Shan Hwang, Hung-Chou Kuo

“…The thermal threshold test combined with nerve conduction tests could detect most of the patients with DSPN, subclinical DSPN, and minimal DSPN. …”
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Applicability of TB-LAMP test for diagnosis of pulmonary TB among HIV-positive individuals by B. Muriithi, M.M. Bundi, T. Moriyasu, A. Ahmed, M. Mwamzuka, M. Karama, S. Kaneko

“…CONCLUSIONS: TB-LAMP demonstrated better agreement with the Xpert assay compared with smear microscopy in detecting TB among HIV-positive patients, suggesting that TB-LAMP could effectively replace smear microscopy.…”
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Managing cognitive impairment in patients with chronic obstructive pulmonary disease (COPD) in Saudi Arabia: what are the current practices? by Rayan A. Siraj, Ahmed M. Alrajeh, Mushabbab A. Alahmari, Fahad H. Alahmadi, Abdulelah M. Aldhahir, Abdullah A. Alqarni, Jaber S. Alqahtani, Saeed M. Alghamdi, Turki M. Alanazi, Abdullah Alruwaili, Saleh S. Algarni, Abdulrhman S. Alghamdi, Tawah H. Alsindi, Mohammed M. Alyami, Faisal A. Alshehri, Talal Alshammari, Rehab Alhasani, Khalid Alrashed, Nawaf E. Sabir, Ataa F. Mesbah

“…Healthcare systems should provide more training and implement a holistic approach to detect and manage cognitive impairment during patients’ visits.…”
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Transcriptome analysis unveils the mechanisms of oxidative stress, immunotoxicity and neurotoxicity induced by benzotriazole UV stabilizer-328 in zebrafish embryos by Xinlu Yang, Yijing Gan, Menghuan Zhang, Shaolin Xie, Mingfu Lin, Lixiang Zhong, Mengke Song, Jun Wang, Yumei Huang

“…As an emerging pollutant, ultraviolet stabilizer-328 (UV-328) has been frequently detected in aquatic environments and attracted great attention. …”
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Feasibility of Screening Primary Aldosteronism by Aldosterone-to-Direct Renin Concentration Ratio Derived from Chemiluminescent Immunoassay Measurement: Diagnostic Accuracy and Cut... by Tianqi Li, Yeshuo Ma, Ying Zhang, Yue Liu, Tingting Fu, Ri Zhang, Kai Kang, Yingchao Yang, Lixin Wang, Yinong Jiang, Yan Lu

“…Aldosterone-to-plasma renin activity ratio (ARR) derived from traditional radioimmunoassay (RIA) is widely used to detect primary aldosteronism (PA). Recently, aldosterone-to-direct renin concentration ratio (ADRR), which is calculated by direct renin concentration (DRC) measured by chemiluminescent immunoassay (CLIA), is proposed to replace ARR as the screening test method for PA. …”
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Anti-Interleukin-22-Neutralizing Antibody Attenuates Angiotensin II-Induced Cardiac Hypertrophy in Mice by Jing Ye, Ling Liu, Qingwei Ji, Ying Huang, Ying Shi, Lei Shi, Jianfang Liu, Menglong Wang, Yao Xu, Huimin Jiang, Zhen Wang, Yingzhong Lin, Jun Wan

“…In addition, angiotensin II-treated mice received an injection of anti-IL-22-neutralizing antibody (nAb) to investigate the effects of IL-22 nAb on myocardial hypertrophy, cardiac function, and cardiac fibrosis; the activation of the signaling pathway and the prohypertrophic inflammatory cytokine mRNA levels was detected. Furthermore, the effect of IL-22 nAb on angiotensin II-induced hypertrophy in vitro was also determined. …”
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Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent by Korfmann, Kevin, Sellinger, Thibaut Paul Patrick, Freund, Fabian, Fumagalli, Matteo, Tellier, Aurélien

“…The current methods developed to detect such multiple merger events do not account for complex demographic scenarios or recombination, and require large sample sizes. …”
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Efficient diagnosis of diabetes mellitus using an improved ensemble method by Blessing Oluwatobi Olorunfemi, Adewale Opeoluwa Ogunde, Ahmad Almogren, Abidemi Emmanuel Adeniyi, Sunday Adeola Ajagbe, Salil Bharany, Ayman Altameem, Ateeq Ur Rehman, Asif Mehmood, Habib Hamam

“…While machine learning (ML) approaches have been widely used to improve early detection and treatment, several studies have shown low classification accuracies due to overfitting, underfitting, and data noise. …”
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Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy by Anna De Lucia, Lucia Mazzotti, Lucia Mazzotti, Anna Gaimari, Anna Gaimari, Matteo Zurlo, Roberta Maltoni, Claudio Cerchione, Sara Bravaccini, Angelo Delmonte, Lucio Crinò, Patricia Borges de Souza, Luigi Pasini, Fabio Nicolini, Fabrizio Bianchi, Manel Juan, Hugo Calderon, Chiara Magnoni, Chiara Magnoni, Luca Gazzola, Luca Gazzola, Paola Ulivi, Massimiliano Mazza

“…Over the past decades, significant progress has been made in the understanding of non-small cell lung cancer (NSCLC) biology and tumor progression mechanisms, resulting in the development of novel strategies for early detection and wide-ranging care approaches. Since their introduction, over 20 years ago, targeted therapies with tyrosine kinase inhibitors (TKIs) have revolutionized the treatment landscape for NSCLC. …”
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Anti-Inflammatory and Antinociceptive Activities of Bufalin in Rodents by Lili Wen, Yang Huang, Xianbiao Xie, Wan Huang, Junqiang Yin, Wenqian Lin, Qiang Jia, Weian Zeng

“…We used a carrageenan-induced paw edema model to assess the anti-inflammatory activity of this compound, and Western blot analysis detected NF-κB signaling during this effect. The antinociceptive activities were evaluated by acetic acid-induced writhing, formalin, and hot-plate tests; open-field test investigated effects on the central nervous system. …”
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Anti-Tumor Effect of Rutin on Human Neuroblastoma Cell Lines through Inducing G2/M Cell Cycle Arrest and Promoting Apoptosis by Hongyan Chen, Qing Miao, Miao Geng, Jing Liu, Yazhuo Hu, Lei Tian, Jingkun Pan, Yi Yang

“…The antiproliferation of rutin in human neuroblastoma cells LAN-5 were detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. …”
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How many stroke survivors develop problematic spasticity requiring pharmacological therapy? An international (Europe and USA) observational study protocol by Pascal Maisonobe, Sergiu Groppa, Simon Page, Richard D Zorowitz, Laura Serrano Barrenechea, Simon Butet, David Hernández Herrero, Rama Prasad, Susan Sandars, Seema Meloni, Alessandro Picelli

“…Participants at sites across seven different countries are monitored remotely at 2 weeks and 1, 2, 3, 6, 9 and 12 months post-stroke to detect the possible onset of PSS using the Post-stroke Spasticity Monitoring Questionnaire (PSMQ). …”
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Using machine learning models to plan HIV services: Emerging opportunities in design, implementation and evaluation by T Dzinamarira, E Mbunge, I Chingombe, D F Cuadros, E Moyo, I Chitungo, G Murewanhema, B Muchemwa, G Rwibasira, O Mugurungi, G Musuka, H Herrera

“…However, barriers such as lack of engagement, limited availability of early HIV-infection detection tools, high rates of HIV/sexually transmitted infections (STIs), barriers to access antiretroviral therapy, lack of innovative resource optimisation and distribution strategies, and poor prevention services for vulnerable populations still exist and substantially affect the attainment of the UNAIDS 95-95-95 targets. …”
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Array Coil Design and Experimental Verification for Separation of Tower Grounding Pulsed Eddy Current Excitation and Response Magnetic Field Signals by Zhiwu Zeng, Zheng Guo, Fan Gan, Yun Zuo, Xu Tian, Xinxun Wang, Zhichi Lin, Wanyi Zhu, Xiaotian Wang, Jingang Wang

“…Transmission line towers play an important role in power transmission, and the assessment of transmission line tower grounding by pulsed eddy current detection technology is conducive to the safe and reliable operation of power transmission. …”
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