Metabolic Alteration in Hepatocellular Carcinoma: Mechanism of Lipid Accumulation in Well-Differentiated Hepatocellular Carcinoma by Hideo Suzuki, Motoyuki Kohjima, Masatake Tanaka, Takeshi Goya, Shinji Itoh, Tomoharu Yoshizumi, Masaki Mori, Mariko Tsuda, Motoi Takahashi, Miho Kurokawa, Koji Imoto, Shigeki Tashiro, Akifumi Kuwano, Masaki Kato, Seiji Okada, Makoto Nakamuta, Yoshihiro Ogawa

“…Similar alterations of metabolic genes were detected in NASH-HCC mice, which were consistent with the results of metabolomics. …”
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Comparison of clinical metagenomics with 16S rDNA Sanger sequencing for the bacteriological diagnosis of culture-negative samples by Camille d’Humières, Skerdi Haviari, Marie Petitjean, Laurène Deconinck, Signara Gueye, Nathan Peiffer-Smadja, Lynda Chalal, Naima Beldjoudi, Geoffrey Rossi, Yann Nguyen, Charles Burdet, Ségolène Perrineau, Diane Le Pluart, Roza Rahli, Michael Thy, Piotr Szychowiak, Xavier Lescure, Véronique Leflon-Guibout, Victoire de Lastours, Etienne Ruppé

“…Clinical metagenomics (CMg), i.e. the sequencing of a sample’s entire nucleic acids, may allow for the identification of bacteria not detected by conventional methods. Here, we tested the performance of CMg compared to 16S rDNA sequencing (Sanger) in 50 patients with suspected bacterial infection but negative cultures. …”
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Morphology of 137 Fast Radio Bursts Down to Microsecond Timescales from the First CHIME/FRB Baseband Catalog by Ketan R. Sand, Alice P. Curtin, Daniele Michilli, Victoria M. Kaspi, Emmanuel Fonseca, Kenzie Nimmo, Ziggy Pleunis, Kaitlyn Shin, Mohit Bhardwaj, Charanjot Brar, Matt Dobbs, Gwendolyn M. Eadie, B.M. Gaensler, Ronniy C. Joseph, Calvin Leung, Robert Main, Kiyoshi W. Masui, Ryan Mckinven, Ayush Pandhi, Aaron B. Pearlman, Masoud Rafiei-Ravandi, Mawson W. Sammons, Kendrick Smith, Ingrid H. Stairs

“…Most multicomponent bursts in our sample exhibit subburst separations of ≤1 ms, with no bursts showing separations < 41 μ s, even at a time resolution of 2.56 μ s, but both scattering and low signal-to-noise ratio can hinder the detection of additional components. Lastly, given the morphological diversity of our sample, we suggest that one-off and repeating FRBs can come from different classes but have overlapping property distributions.…”
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Enhancing Infection Control in ICUS Through AI: A Literature Review by Aditya Amit Godbole, Paras, Maanya Mehra, Sumitaksha Banerjee, Poulami Roy, Novonil Deb, Sarang Jagtap

“…Real‐time patient monitoring and alert systems powered by AI are shown to enhance infection detection and patient outcomes. The paper also addresses AI's role in automating sterilization and disinfection, with studies affirming its effectiveness in reducing infections. …”
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Lactiplantibacillus plantarum ameliorated the negative effects of a low-protein diet on growth performance, antioxidant capacity, immune status, and gut microbiota of laying chicks by Lele Hou, Huiling Qiu, Jihong Dong, Huawei Liu, Shansong Gao, Fu Chen

“…The growth performance, antioxidant capacity, immune status, and gut microbiota of laying chickens were detected. We found that L. plantarum supplementation increased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), total antioxidant capacity (T-AOC), and levels of immunoglobulin (Ig) A, IgG, and interleukin-10 (IL-10) in serum of 17% protein +1.0 × 109 CFU/kg L. plantarum (LPL) compared to the 19% protein group (control). …”
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Residential Indoor and Outdoor PM Measured Using Low-cost Monitors during the Heating Season in Monroe County, NY by Andrea R. Ferro, Naděžda Zíková, Mauro Masiol, Gursumeeran P. Satsangi, Thomas Twomey, David C. Chalupa, David Q. Rich, Philip K. Hopke

“…While the accuracy of LCMs is inconsistent and source dependent, the LCMs provided reasonable precision for estimating indoor/outdoor (I/O) ratios based on laboratory and field testing, understanding the relationship between indoor sources and concentration, and comparing PM concentrations across residences for the detected size range (0.5–3 µm). The indoor PM2.5 concentration pattern showed clear morning and evening peaks as well as higher indoor concentrations during the weekends when people are typically at home. …”
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Prevalence of Dental Caries in Schoolchildren from the Galapagos Islands: ESSO-Gal Cohort Report by Ana Armas-Vega, Juan Marcos Parise-Vasco, María Cristina Díaz-Segovia, David Alejandro Arroyo-Bonilla, María José Cabrera-Dávila, María Christel Zambrano-Bonilla, Ingrid Ordonez-Romero, Andrea Caiza-Rennella, Andrea Zambrano-Mendoza, Celia Ponce-Faula, Andrés Viteri-García

“…The prevalence of dental caries was assessed using the International Caries Detection and Assessment System (ICDAS II) criteria, while the presence of dental biofilm was assessed using the Silness–Löe index. …”
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Advancing privacy-aware machine learning on sensitive data via edge-based continual µ-training for personalized large models by Zhaojing Huang, Leping Yu, Luis Fernando Herbozo Contreras, Kamran Eshraghian, Nhan Duy Truong, Armin Nikpour, Omid Kavehei

“…This paper introduces an innovative method for fine-tuning a large multi-label model for abnormality detection, utilizing a smaller trainer and advanced knowledge distillation techniques. …”
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Fermented soil amendments made from stabilized biosolids and fly ash improve maize (Zea mays L.) nutrition and growth by Karla E. Cortés-Tello, Pablo F Jaramillo-López

“…Cadmium and lead concentrations were below the detection limits both in the soil amendments and in the tissue of maize plants.…”
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Experimental study of the effects of siestas on the nocturnal sleep quality and thermal comfort levels under thermoneutral environment in summer by Huili Yu, Xue Zhao, Liping Chen, Xiaohui Tian, Shimin Liang, Songtao Hu

“…Higher DA concentration was also detected in the siesta group after the nocturnal sleep. …”
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Alpha-1 Antitrypsin Deficiency and Pulmonary Morbidity in Patients with Primary Immunodeficiency Disease: A Single-Center Experience by Georg Evers, Arik Bernard Schulze, Michael Thrull, Jan-Philipp Hering, Christoph Schülke, Rainer Wiewrodt, Helmut Wittkowski, Lars Henning Schmidt, Michael Mohr

“…Among the investigated patients, reduced serum AAT levels were detected in 7 patients. With regard to the genotype, PI∗ZZ was found in 2 patients, whereas PI∗MZ was observed in 5 patients. …”
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Long-term Breast Shape Analysis After Short-scar Reduction Mammaplasty: A Critical View by Daniel Hilewitz, MD, Oren Ganor, MD, Neta Adler, MD, Asaf Olshinka, MD, Dafna Shilo Yaacobi, MD, Lior Har-Shai, MD, Tamir Shay, MD, Michael Icekson, MD, Dean Ad-El, MD, Sagit Meshulam-Derazon, MD

“…The nipple-to-inframammary fold distance, which was intraoperatively shortened by an average of 63%, elongated back to 88% of its preoperative measurements. No correlation was detected between the long-term changes across all 3 measurements, the amount of tissue removed or the satisfaction reported by patients. …”
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RETRACTED: LncRNA CCAT2 promotes the proliferation and metastasis of colorectal cancer through activation of the ERK and Wnt signaling pathways by regulating GNB2 expression by Jinhai Tian, Xu Cao, Zongying Jiang, Jia Wang, Wan Fan, Shaoting Zhang, Sien Zhao, Jianmin Sun

“…Methods High‐throughput sequencing and RT‐qPCR were used to detect CCAT2 expression in CRC. Functional analyses including CCK8, colony formation, wound healing migration, transwell chamber, and Muse® Cell Analyzer assays were performed to study the effects of CCAT2 gene deletion on CRC cells. …”
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The Effect of IL-4 Gene Polymorphisms on Cytokine Production in Patients with Chronic Periodontitis and in Healthy Controls by Jirina Bartova, Petra Borilova Linhartova, Stepan Podzimek, Tatjana Janatova, Kazi Svobodova, Antonin Fassmann, Jana Duskova, Jaromir Belacek, Lydie Izakovicova Holla

“…Sixty-two subjects (47 CP patients and 15 healthy controls) with detected two polymorphisms in the IL-4 gene (-590C/T and intron 3 VNTR) were examined. …”
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Microstructure evolution and recrystallization behavior of two nickel-based single crystal superalloys by XU Fuze, LIN Yongcheng, MA Dexin, HE Daoguang, ZHAO Yunxing, LI Lyu, CHENG Bowen, DENG Yangpi

“…Conversely， no RX was detected in the DD5 SC test plate post-treatment at 1300 ℃. …”
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Effects of endocrine disrupting chemicals, blood metabolome, and epigenetics on breast cancer risk: A multi-dimensional mendelian randomization study by Ningning Song, Xinquan Xi, Kuan Yang, Chongzhe Pei, Lingzhou Zhao

“…These findings not only suggest potential biomarkers for early detection and intervention but also underscore the imperative for further research to rigorously validate these associations.…”
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Determining the effect of frailty on survival in advanced ovarian cancer: study protocol for a prospective multicentre national cohort study (FOLERO) by Daniel Hunde, Niklas Ekerstad, Mihaela Asp, Päivi Kannisto, Madelene Wedin, Charlotte Palmqvist, Pernilla Dahm-Kähler, Yvonne Brandberg, Mirna Abraham-Nordling, Kristina Åhlund, Vilhelm Mörlin, Nina Groes-Kofoed, Sahar Salehi

“…With a fixed sample size of 450 patients, a two-sided α of 0.05 and β of 0.20, the study is powered to detect a difference in 2-year survival of 12.5% by frailty, assuming a 20% prevalence of frailty. …”
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Effects of early neonatal proinflammatory stress on the expression of BDNF transcripts in the brain regions of prepubertal male rats by D. I. Peregud, S. V. Freiman, A. O. Tishkina, L. S. Sokhranyaeva, N. A. Lazareva, M. V. Onufriev, M. Y. Stepanichev, N. V. Gulyaeva

“…BDNF polypeptide concentration was estimated by means of an enzyme-linked immunosorbent assay, while quantitative polymerase chain reaction followed by reverse transcription was used to detect exon-specific BDNF mRNA expression. The levels of BDNF and transcripts, containing common exon IX were similar in the control and LPS-treated rats. …”
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Comprehensive analysis of publications concerning combinations of immunotherapy and targeted therapies for hepatocellular carcinoma: a bibliometric study by Biling Gan, Lei Wu, Shunan Zhou, Zhihong Chen, Fan Wu, Lianqun Xu, Zhenrong Chen, Honghui Ma, Peijia He, Dan Fang, Ning Shi

“…This study provides a bibliometric overview of these therapeutic combinations, evaluating their development and impact.MethodsA rigorous selection process was applied to relevant literature from Web of Science, followed by in-depth bibliometric analyses— including timeline visualization, burst detection, and co-occurrence analysis—using CiteSpace and VOSviewer. …”
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Separation of Inorganic Forms of Tellurium Using On-Site SPE Followed by ICP-MS or ICP-OES—The Right Solution for Water Monitoring by Katarzyna Kińska, Barbara Żelazko, Olga Gajewska, Magdalena Borowska, Monika Sadowska, Beata Krasnodębska-Ostręga

“…The proposed SPE-ICP-MS (inductively coupled plasma mass spectrometry) method allows direct analysis of Te(VI) and Te(IV), with Te(IV) determined after elution from the column. The detection limits obtained for the 5.0 mL sample are 0.02 ng mL⁻¹ and 0.05 ng mL⁻¹ for Te(VI) and Te(IV), respectively. …”
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