Simultaneous Determination of Six Components in Beagle Dog Plasma by UPLC-MS/MS and Its Application to a Comparative Pharmacokinetic Study of Three Different Yuanhu Zhitong Prepara... by Yang Wang, Zhaorui Yin, Kai Zhang, Qingfen Meng, Jianli Guan, Guanwei Fan

“…Six analytes and one internal standard were separated on a Waters Acquity UPLC BEH C18 column (2.1 mm × 100 mm, 1.7 μm) by gradient elution with 0.1% formic acid-water and 0.1% formic acid-acetonitrile at a flow rate of 0.4 mL/min. Detection was conducted by multiple reaction monitoring mode in the positive ionization. …”
Get full text

Papaverine Enhances the Oncolytic Effects of Newcastle Disease Virus on Breast Cancer In Vitro and In Vivo by Sura Akram, Ahmed Majeed Al-Shammari, Hayder B. Sahib, Majid Sakhi Jabir

“…The study included a cell viability MTT assay, morphological analysis, and apoptosis detection. Animal experiments used the AN3 mouse mammary adenocarcinoma tumor model. …”
Get full text

Assessment of Angiography-Based Renal Quantitative Flow Ratio Measurement in Patients with Atherosclerotic Renal Artery Stenosis by Xiang Huang, Xiao-Lan Li, Heng Zhou, Xiao-Mei Li

“…The rQFR has the potential to enhance the ability of angiography to detect functionally significant renal artery stenosis during angiography and to produce results that are comparable to invasive hemodynamic assessment.…”
Get full text

Expression of the transcription factor encoding gene <i>StTCP23</i> in potato plants infected with the tuber spindle viroid by N. V. Mironenko, A. S. Orina, N. M. Lashina, О. S. Afanasenko

“…Symptoms of infecting ‘Colomba’ plants with the PSTVd viroid strain NicTr-3 were not detected, while the presence of the viroid in potato leaves was confirmed by molecular methods. …”
Get full text

Robust Forest Sound Classification Using Pareto-Mordukhovich Optimized MFCC in Environmental Monitoring by Ahmad Qurthobi, Robertas Damasevicius, Vytautas Barzdaitis, Rytis Maskeliunas

“…This study focuses on the application of deep learning models for forest sound classification as an effort to establish an early threats detection system. The research evaluates the performance of several pre-trained deep learning models, including MobileNet, GoogleNet, and ResNet, on the limited FSC22 dataset, which consists of 2,025 forest sound recordings classified into 27 categories. …”
Get full text

LncRNA HOTAIR: A Novel Biomarker for the Diagnosis of Asymptomatic Carotid Artery Stenosis and Prediction of the Onset of Cerebral Ischemic Events by Pengcheng Feng, Chenguang Tong, Yuan Li, Li Liu

“…Blood samples were collected and serum HOTAIR levels were detected by qRT-PCR. Logistic regression examined factors associated with the degree of carotid stenosis. …”
Get full text

Optimization of Extraction of Compound Flavonoids from Chinese Herbal Medicines Based on Quantification Theory and Evaluation of Their Antioxidant Activity by Xu Yang, Dongli Cao, Haiyu Ji, Yingying Feng, Juan Yu, Anjun Liu

“…This study aims to optimize the extraction process of compound flavonoids (CFs) from Chinese herbal medicines and detect their antioxidant activity in vitro. CFs were extracted from the raw materials named “medicine food homology,” composed of hawthorn, lotus leaf, tartary buckwheat, cassia seed, Lycium barbarum, and Poria cocos in a mass ratio of 4 :  2 :  2 :  1.5 :  1 :  1. …”
Get full text

A new STI in the city: MPOX in Barcelona. First outbreak (5/2022-5/2023) and subsequent resurgence. by David Palma, Montserrat Guillaumes, Carles Pericas, Anna de Andrés, Raquel Prieto, Laia Álvarez-Bruned, Jesús Ospina, Paula Santiá, Patricia García de Olalla, Cristina Rius

“…<h4>Background</h4>In May 2022, after the suspension of the mobility restrictions due to the COVID-19 pandemic, the first outbreak of MPOX virus, transmitted from human to human, was detected outside of Africa, affecting mostly sexually active men who have sex with men. …”
Get full text

Evaluation of genotoxic potential induced by marine cage culture by F. Turan, M. Turgut

“…DNA damage biomarkers for fish species detect genotoxic parameters for ecological risk assessment. …”
Get full text

Estimating the Growing Degree Days in the Northwest of Iran based on Climate Change Models by Hasan Zolfaghari, Jafar Masoompourv Samakosh, Shabnam Chahvari

“…In total the most temperature increasing was detected as 0/7 centigrade in A2 scenario for 2011-2030 period and 2/3 centigrade under A1B scenario for 2046-2065 period. …”
Get full text

Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro by Miao Liu, Wen-jie Xie, Xu Zhang, Wei Wu, Guang Li, Lu Wang

“…Takeda G protein-coupled receptor 5 (TGR5) and β-arrestin2 expression and macrophage polarization markers were detected with or without SB. Results TGR5 was identified as the target of butyric acid. …”
Get full text

Stromal Expression of Hypoxia Regulated Proteins Is an Adverse Prognostic Factor in Colorectal Carcinomas by Arjen H. G. Cleven, Manon van Engeland, Bradly G. Wouters, Adriaan P. de Bruïne

“…Results: Expression of these hypoxia markers was detected in the epithelial compartment of the tumor cells as well as in tumor-associated stromal cells. …”
Get full text

16S rRNA metabarcoding applied to the microbiome of insect products (novel food): a comparative analysis of three reference databases by Gabriele Spatola, Alice Giusti, Laura Gasperetti, Roberta Nuvoloni, Alessandra Dalmasso, Francesco Chiesa, Andrea Armani

“…A total of 121 genera were identified, with 56.2% detected by all three databases, though some taxa were identified only by one or two. …”
Get full text

Synthesis and Optical Properties of Triphenylene-Based Donor-Donor and Donor-Acceptor Conjugated Polymers: A Comparative Study by Yong Li, Dung D. Nguyen, Kuldeep Shetye, Zhonghua Peng

“…By virtue of the very different fluorescence properties of these two polymers in nonpolar solvents such as hexane and in polar solvents, the potential of using the polymers to detect the trace amount of ethanol content that is added to gasoline has been revealed with high sensitivity.…”
Get full text

The consistency and efficacy of optical coherence tomography for the evaluation of ocular torsion angle in children by Rongjun Liu, Jingjing Zhao, Kaili Yu, Dehai Zhu

“…OCT was used to automatically detect the centers of the optic disc and fovea, and the software then calculated the FDA on the same device. …”
Get full text

Statistical analysis of heat waves in the southern slopes of Alborz by Zienab Hosinpoor, AliAkbar Shamsipour, Mostafa Karimi, Faramarz khoshakhlagh

“…Heat waves are important phenomena in Iran, And its upsurge in recent years seems to have a high upside trend.This climate has a negative impact on agriculture, forest fire and forestry, water resources, energy use and human health.The purpose of the research is to explain the frequency, time distribution, continuity of thermal waves, and the identification of its occurrence in the southern foothills of central Alborz.Therefore, using the statistical methods and maximum daily temperature data of Tehran (Mehrabad), Qazvin and Semnan stations for the statistical period of 30 years (1966-2016), the mentioned characteristics were extracted.In the first step, the nonparametric method of Kendal was used to understand the variability and awareness of the monthly trend of maximum temperatures in the study period.In order to determine the severity, duration and frequency of heat wave events, the percentiles (95.98) and normalized temperature deviation (NTD) were used.The results of the study showed that the frequency of short-wave heat waves was higher.Most frequencies are related to 2-day waves, respectively, and Tehran (Mehrabad), Semnan and Qazvin stations are more frequent.The highest frequency of annual events was detected at stations in Tehran (11 waves in 2010), in Semnan (9 waves in 2015) and Qazvin (7 waves in 2015), respectively.The highest frequency of monthly heat wave events was recorded in June and September.The highest continuation (15 days) was obtained in March 2008 with the percentile method at Mehrabad station.In the normalized deviation method, the temperature was calculated as a warm wave (12 days) in 2008.The highest annual frequency of heat loss occurred in all three stations in 2015.The evolution of the process indicated an increase in the incidence of thermal waves in the cold period of the year But in other chapters, no meaningful changes were made.As it says, the decline in cold winter temperatures is on the southern slopes of Alborz.The results of the two methods showed that in the normalized deviation of the temperature, the number of thermal waves more than the percentile method was recorded, but in the percentile method, the thermal wave was more prominent in the cold period of the year.…”
Get full text

Differentially Expressed MicroRNAs in the Development of Early Diabetic Retinopathy by Qiaoyun Gong, Jia’nan Xie, Yang Liu, Ying Li, Guanfang Su

“…Because microRNAs (miRNAs) represent effective DR therapeutic targets, we identified aberrantly expressed miRNAs associated with cellular dysfunction in early DR and detected their potential targets. We exposed human retinal endothelial cells (HRECs) and a cell line of retinal pigment epithelial (RPE) cells to high glucose (25 mmol/L, 1–7 days) to mimic DR progression and used streptozotocin-injected rats (4–8 weeks) for an in vivo diabetes model. …”
Get full text

Debris Extrusion Using Reciproc Blue and XP Endo Shaper Systems in Root Canal Retreatment by Taher AlOmari, Ruba Mustafa, Rami Al-Fodeh, Hamza El-Farraj, Waheeb Khaled, Ahmed Jamleh

“…XPS extruded less debris than RB, but no difference was detected (Mann–Whitney test; P>0.05). RB and XPS required 54.9 ± 17.9 and 22.3 ± 9.3 seconds to perform retreatment procedures, respectively (Mann–Whitney test; P<0.05). …”
Get full text

Responsiveness of hand-held dynamometry for measuring changes in trunk muscle strength in people with chronic low back pain by Shouq Althobaiti, Janet A. Deane, Deborah Falla

“…Conclusions Although the use of a HHD was shown to have internal responsiveness for detecting changes in trunk muscle strength, the inadequate external responsiveness warrants further investigation. …”
Get full text

Development of a Novel Algorithm to Identify People with High Likelihood of Adult Growth Hormone Deficiency in a US Healthcare Claims Database by Kevin C. J. Yuen, Anna Camilla Birkegard, Lewis S. Blevins, David R. Clemmons, Andrew R. Hoffman, Nicky Kelepouris, Janice M. Kerr, Jens M. Tarp, Maria Fleseriu

“…This algorithm may represent a cost-effective approach to improve AGHD detection rates by identifying appropriate patients for further diagnostic testing and potential GH replacement treatment.…”
Get full text