Impact of the transition from radioimmunoassay (RIA) to chemiluminescent enzyme immunoassay (CLEIA) for the measurement of plasma aldosterone concentration (PAC) on the diagnosis o... by Ken-ichiro Honma, Yoshiro Nakayama, Atsuko Tamaki, Moriyuki Uehara, Taiki Teruya, Takamitsu Yabiku, Yohei Ishiki, Ken Yonaha, Rei Chinen, Tsugumi Uema, Shiki Okamoto, Hiroaki Masuzaki

“…In Japan, the traditional method for measuring plasma aldosterone concentration (PAC) was radioimmunoassay (RIA), which had several challenges, including poor traceability of certified reference materials and reduced detection sensitivity at low concentrations. To overcome these issues, a chemiluminescent enzyme immunoassay (CLEIA) for PAC measurement was introduced in April 2021 and the Japan Endocrine Society published new guidelines for primary aldosteronism (PA). …”
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Antimicrobial Susceptibility of <i>Glaesserella parasuis</i> to Macrolides and Characterization of <i>erm</i>(T)-Carrying Mobile Elements on Chromosome by Peng Zhang, Changmin Li, Shuna Shang, Ting Huang, Junqi Liu, Qianwen Ge, Xiaoping Liao, Liangxing Fang, Yang Yu

“…The macrolide resistance gene <i>erm</i>(T) and the A2059G mutation in 23S rRNA were detected in the current study. To the best of our knowledge, integrative and conjugative element (ICE)-borne <i>erm</i>(T) in <i>G. parasuis</i> is reported for the first time in this study. …”
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A Novel Authentication Management for the Data Security of Smart Grid by Imtiaz Parvez, Maryamossadat Aghili, Hugo Riggs, Aditya Sundararajan, Arif I. Sarwat, Anurag K. Srivastava

“…The second layer monitors and verifies exchanged data packets among smart meters. It detects abnormal packets from suspicious sources. …”
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Influence of mimicry on extinction risk in Aculeata: a theoretical approach by Boutin, Maxime, Costa, Manon, Fontaine, Colin, Perrard, Adrien, Llaurens, Violaine

“…We found that the probability of extinction increases as the proportion of undefended males increases in the population, however co-existence still occurs if females are sufficiently abundant or noxious. Furthermore, we detected a destabilising effect of dual sex-limited mimicry (when each sex resembles a different model) on species co-existence. …”
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Prevalence and Subtype Analysis of Blastocystis hominis Isolated from Patients in the Northeast of Iran by Mitra Salehi, Jalal Mardaneh, Hamid Reza Niazkar, Mohammadhaasan Minooeianhaghighi, Elahe Arshad, Fateme Soleimani, Alireza Mohammadzadeh

“…From 1878 collected stool samples, 152 (8.1%) Blastocystis samples were detected by the microscopic method. Of the 152 samples, Blastocystis spp. were found in 53.6% of the men and 28.9% of the women who showed clinical gastrointestinal symptoms, and a significant relationship was observed between gender and clinical symptoms (P=0.002). …”
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Effect of IRAK-M on Airway Inflammation Induced by Cigarette Smoking by Haihong Gong, Tao Liu, Wei Chen, Weixun Zhou, Jinming Gao

“…A number of cellular and molecular techniques were used to detect the differences between IRAK-M knockout (KO) and wild type (WT) mice exposed to 3-day or 7-week CS. …”
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Exploring predisposing factors of hearing loss in prematurely born children: A nationwide case-control study by Pei-Chen Tsao, Hung-Chih Lin, Shang-Po Shen, Yu-Chia Chang

“…Conclusion: To reduce the incidence of childhood HL in prematurely born children, aggressive management of premature birth-related consequences and treatable causes and longitudinal audiological follow-up with early detection and adequate intervention are crucial.…”
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Optimizing Bioaugmentation for Pharmaceutical Stabilization of Sewage Sludge: A Study on Short-Term Composting Under Real Conditions by Gabriela Angeles-De Paz, Juan Cubero-Cardoso, Clementina Pozo, Concepción Calvo, Elisabet Aranda, Tatiana Robledo-Mahón

“…A significant concentration of pharmaceuticals has been detected within composted sewage sludge. Their uncomplete removal and lack of monitoring during composting neglects their potentially toxic effects when used as a soil organic amendment. …”
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Fas Ligand DNA Enhances a Vaccination Effect by Coadministered DNA Encoding a Tumor Antigen through Augmenting Production of Antibody against the Tumor Antigen by Boya Zhong, Guangyu Ma, Ayako Sato, Osamu Shimozato, Hongdan Liu, Quanhai Li, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa

“…Growth of β-gal-positive Colon 26 tumors was retarded in the syngeneic mice immunized with β-gal and FasL DNA compared with those vaccinated with β-gal or FasL DNA. We did not detect increased numbers of β-gal-specific CD8+ T cells in lymph node of mice that received combination of β-gal and FasL DNA, but amounts of anti-β-gal antibody increased with the combination but not with β-gal or FasL DNA injection alone. …”
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ASKAP Observations of the Radio Shell in the Composite Supernova Remnant G310.6-1.6 by Wenhui Jing, Jennifer L. West, Xiaohui Sun, Wasim Raja, Xianghua Li, Lingxiao Dang, Ping Zhou, Miroslav D. Filipović, Andrew M. Hopkins, Roland Kothes, Sanja Lazarević, Denis Leahy, Emil Lenc, Yik Ki Ma, Cameron L. Van Eck

“…We report the observations of the radio shell of the supernova remnant (SNR) G310.6–1.6 at 943 MHz from the Evolutionary Map of the Universe (EMU) and the Polarization Sky Survey of the Universe’s Magnetism (POSSUM) surveys by using the Australian Square Kilometre Array Pathfinder (ASKAP). We detect polarized emission from the central pulsar wind nebula (PWN) with rotation measures varying from –696 rad m ^−2 to –601 rad m ^−2 . …”
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Staphylococcus aureus carriage is associated with microbiome composition in the nares and oropharynx, not the hand, of monozygotic twins by Mark R. Dalman, W. Brian Simison, Danny Nielsen, Sabana Bhatta, Noor Ramahi, Clair Yee, Dipendra Thapaliya, Jhalka Kadariya, Shanice Cheatham, Hailee Olson, Tara C. Smith

“…The prevalence of S. aureus was highest in the oropharynx followed by nares and hand with concordance between twin pairs highest in the nares, followed by oropharynx. The detection of S. aureus was statistically correlated with differences in microbiome composition across sites, as indicated by beta diversity and DESeq2 analyses. …”
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Resolving the electronic ground state of La3Ni2O7-δ films by Xiaolin Ren, Ronny Sutarto, Xianxin Wu, Jianfeng Zhang, Hai Huang, Tao Xiang, Jiangping Hu, Riccardo Comin, Xingjiang Zhou, Zhihai Zhu

“…Additionally, in La3Ni2O7-δ films, we detect a superlattice reflection (1/4, 1/4, L) at the Ni L absorption edge using resonant X-ray scattering measurements. …”
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3D Semantic VSLAM of Indoor Environment Based on Mask Scoring RCNN by Chongben Tao, Yufeng Jin, Feng Cao, Zufeng Zhang, Chunguang Li, Hanwen Gao

“…In order to achieve object detection and semantic segmentation for both static objects and dynamic objects in indoor environments and then construct dense 3D semantic map with VSLAM algorithm, a Mask Scoring RCNN is used to adjust its structure partially, where a TUM RGB-D SLAM dataset for transfer learning is employed. …”
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Determination of Residual Nonsteroidal Anti-Inflammatory Drugs in Aqueous Sample Using Magnetic Nanoparticles Modified with Cetyltrimethylammonium Bromide by High Performance Liqui... by Malihe Khoeini Sharifabadi, Mohammad Saber-Tehrani, Syed Waqif Husain, Ali Mehdinia, Parviz Aberoomand-Azar

“…The calibration curves obtained for studied drugs show reasonable linearity (R2>0.99) and the limit of detection (LODs) ranged between 2 and 7 ng/mL. Finally, the proposed method has been effectively employed in extraction and determination of the drugs in biological and environmental samples.…”
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The Silent Threat of Human Metapneumovirus: Clinical Challenges and Diagnostic Insights from a Severe Pneumonia Case by Rubens Carmo Costa-Filho, Felipe Saddy, João Luiz Ferreira Costa, Leandro Reis Tavares, Hugo Caire Castro Faria Neto

“…Background: Human metapneumovirus (hMPV) is a respiratory pathogen that has gained increasing recognition due to advancements in molecular diagnostic tools, which have improved its detection and characterization. While severe disease manifestations are traditionally associated with pediatric, elderly, or immunocompromised patients, hMPV-related pneumonia in immunocompetent adults remains underexplored. …”
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Comparative Analysis of AES, Blowfish, Twofish, Salsa20, and ChaCha20 for Image Encryption by Rebwar Khalid Muhammed, Ribwar Rashid Aziz, Alla Ahmad Hassan, Aso Mohammed Aladdin, Shaida Jumaah Saydah, Tarik Ahmed Rashid, Bryar Ahmad Hassan

“…The recognition of threats and attacks meant for knowledge and safety on the internet is growing harder to detect. Since cybersecurity guar-antees the privacy and security of data sent via the Internet, it is essential, while also providing protection against malicious attacks. …”
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Study protocol for the development and pilot-testing of a Self-assessment tool for the implementation of the European Standards of Care for Newborn Health (ESCNH) by James Webbe, Helmut Hummler, Luc J I Zimmermann, Ylva Thernström Blomqvist, Nicholas Lack, Dietmar Schlembach, Julia Hoffmann, Silke Mader, Eleni Vavouraki, Sarah Lehmann, Gina Ancora, Esther Schouten, Ilaria Simonelli, Isabel Geiger

“…We aim to develop a digital self-assessment tool for HCPs to detect the local level of ESCNH fulfilment and identify areas in need of improvement, and thus provide recommendations for action.Methods and analysis The self-assessment tool will have the form of a digital questionnaire with condensed ESCNH content. …”
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SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection by Richard C. Crist, Samar N. Chehimi, Saurabh S. Divakaran, Michael J. Montague, Sébastien Tremblay, Noah Snyder-Mackler, Martin O. Bohlen, Kenneth L. Chiou, Trish M. Zintel, Cayo Biobank Research Unit, Michael L. Platt, Halvor Juul, Guido Silvestri, Matthew R. Hayes, Dennis L. Kolson, Benjamin C. Reiner

“…Differential expression identified alterations in cellular subtype gene expression that persisted over the 20-day time course and short-lived differences only detected at 10-days post-SIV infection. In silico predicted regulatory mechanisms and dysregulated neural signaling pathways are presented. …”
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Comparison of Immunomodulation Properties of Porcine Mesenchymal Stromal/Stem Cells Derived from the Bone Marrow, Adipose Tissue, and Dermal Skin Tissue by Sun-A Ock, Raghavendra Baregundi Subbarao, Yeon-Mi Lee, Jeong-Hyeon Lee, Ryoung-Hoon Jeon, Sung-Lim Lee, Ji Kwon Park, Sun-Chul Hwang, Gyu-Jin Rho

“…Except for the lipoprotein gene, there were no marked changes in osteogenesis- and adipogenesis-related genes following in vitro differentiation; however, the histological marker analysis revealed that adipose MSCs could be differentiated into both adipose and bone tissue. TGFβ and IL10 were detected in adipose MSCs and bone marrow MSCs, respectively. …”
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Phosphatidylserine on sperm head interact with Annexin A5 on oviduct luminal cilia to form a sperm reservoir in pigs by Lorraine Schmaltz, Elie Barakat, Renaud Fleurot, Rustem Uzbekov, Karine Reynaud, Ludivine Laffont, Guillaume Tsikis, Isabelle Mérour, Pascal Mermillod, Marie Saint-Dizier

“…Our objective was to explore the role of annexin A5 (ANXA5), a protein that binds with high affinity to phosphatidylserine (PS), in the formation of the sperm reservoir in pigs.Phosphatidylserine was detected on the head of approximately 10 % of boar sperm at ejaculation. …”
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