The Effect of PVP Molecular Weight on Dissolution Behavior and Physicochemical Characterization of Glycyrrhetinic Acid Solid Dispersions by Xiaoyu Sui, Yan Chu, Jie Zhang, Honglian Zhang, Huiyu Wang, Tingting Liu, Cuiyan Han

“…Based on FTIR and Raman detection, a hydrogen-bond between PVP and drug molecules is formed. …”
Get full text

Early Diagnosis of Alzheimer’s Disease Using Adaptive Neuro K-Means Clustering Technique by Karan Kumar, Shweta Agrawal, Isha Suwalka, Celestine Iwendi, Cresantus N. Biamba

“…Implemented in MATLAB, this method provides a robust, efficient framework for early AD detection, surpassing existing approaches in precision and reliability.…”
Get full text

Synaptic enrichment and dynamic regulation of the two opposing dopamine receptors within the same neurons by Shun Hiramatsu, Kokoro Saito, Shu Kondo, Hidetaka Katow, Nobuhiro Yamagata, Chun-Fang Wu, Hiromu Tanimoto

“…For cell-type-specific visualization of endogenous proteins, we employed reconstitution of split-GFP tagged to the receptor proteins. We detected dopamine receptors at both presynaptic and postsynaptic sites in multiple cell types. …”
Get full text

Circle of Willis Variants: Fetal PCA by Amir Shaban, Karen C. Albright, Amelia K. Boehme, Sheryl Martin-Schild

“…Patients with complete fPCA were older and more often female than partial fPCA and no fPCA patients, and significant variation in TOAST classification was detected across groups (). Patients with complete fPCA had less small vessel and more large vessel strokes than patients with no fPCA and partial fPCA. …”
Get full text

Guidelines for the Management of Complications of Diabetes in Saudi Arabia Using Delphi Technique for Consensus Among National Experts by Raed Aldahash, Mohammed A. Batais, Ashraf El-Metwally, Saja Alhosan, Mohammed Alharbi, Mohammed Almutairi, Abdulghani Alsaeed, Mohammed Alsofiani, Mohammed AlMehthel, Mohammed Aldubayee, Khaled Aldossari, Sulieman Alshehri

“…The guidelines offer useful insights into diabetes care, especially by prioritizing early detection and proactive management of complications. …”
Get full text

Variants in the 3′ End of SLC6A3 in Northwest Han Population with Parkinson’s by Peiye Chang, Yongwang Fu, Ping Zhao, Chunmei Wang, Mingfang Jiang, Rui Li, Yulin He

“…The significant difference of gene type and allele frequencies between the PD and control groups was detected only in rs40184 (P = 0.013 and 0.004, respectively; odds ratio 2.529, 95% confidence interval 1.325–4.827). …”
Get full text

Analysis of Biomolecular Changes in HeLa Cervical Cancer Cell Line Induced by Interaction with [Pd(dach)Cl₂] by Vanja Ralić, Maja D. Nešić, Tanja Dučić, Milutin Stepić, Lela Korićanac, Katarina Davalieva, Marijana Petković

“…Although a certain level of lipid peroxidation was detectable by SR FTIR spectroscopy and confirmed by an analysis of cellular lipids by matrix-assisted laser desorption and ionisation time-of-flight mass spectrometry, the oxidative stress is not a significant mechanism by which Pd(II) expresses the effect on the HeLa cells.…”
Get full text

Corneal Backscatters as an Objective Index for Assessing Fuchs’ Endothelial Corneal Dystrophy: A Pilot Study by Hsueh-Yen Chu, Ching-Hsi Hsiao, Phil Yeong-Fong Chen, David Hui-Kang Ma, Chee-Jen Chang, Hsin-Yuan Tan

“…It can assist ophthalmologists in detecting the early change and in monitoring disease progression of FECD. …”
Get full text

Young Cuban Patients with a Clinical and biochemical Diagnosis of Xeroderma Pigmentosum by Judith Beatriz Pupo Balboa, Mónica Marín García, Anamarys Pandolfi Blanco, Lucía Fariñas Rodríguez, Paulina Araceli Lantigua Cruz

“…In all four patients, expression of eta polymerase was detected by western blot; in the two who had normal repair, the protein band was weak, indicating that they might have the variant of the disease. …”
Get full text

Short Supply of High Levels of Guanidine Acetic Acid, Alters Ovarian Artery Flow and Improves Intraovarian Blood Perfusion Area Associated with Follicular Growth in Sheep by Marta da Costa Sousa, Camila Muniz Cavalcanti, Alfredo José Herrera Conde, Bruna Vitória de Freitas Alves, Larissa Fernandes Baia Cesar, Jhennyfe Nobre de Sena, Yohana Huicho Miguel, César Carneiro Linhares Fernandes, Juliana Paula Martins Alves, Dárcio Ítalo Alves Teixeira, Davide Rondina

“…Twenty adult sheep had their estrus synchronized using an MPA sponge, eCG, and PGF2α. After estrus detection ewes were mated. For 10 days until mating, ewes were grouped in groups of baseline diet (BSD; n = 10) and GAA diet (GAAD; n = 10), which was the BSD with daily 0.9 g/kg DM of GAA. …”
Get full text

mRNA Expression of EgCHI1, EgCHI2, and EgCHI3 in Oil Palm Leaves (Elaeis guineesis Jacq.) after Treatment with Ganoderma boninense Pat. and Trichoderma harzianum Rifai by Laila Naher, Soon Guan Tan, Chai Ling Ho, Umi Kalsom Yusuf, Siti Hazar Ahmad, Faridah Abdullah

“…Basal stem rot (BSR) disease caused by the fungus Ganoderma boninense is the most serious disease affecting the oil palm; this is because the disease escapes the early disease detection. The biocontrol agent Trichoderma harzianum can protect the disease only at the early stage of the disease. …”
Get full text

The anomalously thundery month of June 1925 in southwest Spain: description and synoptic analysis by F. J. Acero, M. Antón, A. J. P. Aparicio, A. J. P. Aparicio, N. Bravo-Paredes, V. M. S. Carrasco, M. C. Gallego, J. A. García, M. Núñez, I. Tovar, J. Vaquero-Martínez, J. M. Vaquero

“…<p>In a routine search for meteorological events with a great impact on society in the Extremadura region (southwest interior of the Iberian Peninsula) using newspapers, the month of June 1925 was detected as exceptional due to the large number of thunderstorms associated with significant losses of human lives and material resources. …”
Get full text

Assessment of changes in vitamin content and morphological characteristics in strawberries modified with a pulsed electric field using chromatography and optical coherence tomograp... by Ewa Korzeniewska, Ilona Gałązka-Czarnecka, Joanna Sekulska-Nalewajko, Jarosław Gocławski, Tomasz Dróźdż, Paweł Kiełbasa

“…Experiments have shown that PEF treatment with an intensity of 1 kV/cm and 10 pulses for 10 s resulted in a significant improvement in vitamin content and extraction efficiency of vitamin C by 22 %, folic acid by 24 %, thiamine by more than 50 % and riboflavin by more than 60 %.Optical coherence tomography imaging revealed texture changes in fruit pulp under the influence of PEF, related to the release of additional vitamins detected by chromatography methods.Additionally, PEF treatment offers significant benefits in fruit processing, including improved dehydration characteristics, reduced time and energy required for freeze-drying, increased extraction efficiency, and potential improvements in bioactive compound content and antioxidant properties.The research results may have practical applications in the analytical determination of vitamins C and B by improving the extraction efficiency. …”
Get full text

Downregulation of CD4+LAP+ and CD4+CD25+ Regulatory T Cells in Acute Coronary Syndromes by Ying-zhong Lin, Shan-he Lu, Zheng-de Lu, Ying Huang, Ying Shi, Ling Liu, Xiao-yan Wang, Qing-wei Ji

“…The frequencies of CD4+LAP+ and CD4+CD25+ Treg cells were detected using flow cytometric analysis, and the plasma IL-10 and TGF-β1 levels were measured using an ELISA in 29 stable angina (SA) patients, 30 NSTEACS patients, 27 STEAMI patients, and a control group (30 cases). …”
Get full text

Routine Head Computed Tomography for Patients in the Emergency Room with Trauma Requires Both Thick- and Thin-Slice Images by Kazuhide Maetani, Jun Namiki, Shokei Matsumoto, Katsutoshi Matsunami, Atsushi Narumi, Toshimi Tsuneyoshi, Masanobu Kishikawa

“…A routine head CT of the supratentorial region for patients in the ER with head injuries requires both thick-slice images to visualize cerebral hemispheres and thin-slice images to detect skull fractures of the cranial vault.…”
Get full text

New method for cytological evaluation using direct nipple discharge without aspiration by Jiang Zhu, Han Cong, Xiaotong Zhang, Xiaoya Dong, Song Zhao, Chaolu Hu, Jude Ranchu Maimo, Yawen Wang, Kai Zhang, Jianli Wang, Pengyu Li, Rong Ma

“…Therefore, LBC provides a new and better diagnostic method for early detection of breast tumors with nipple discharge.…”
Get full text

Traditional Uses, Bioactive Compounds, and Pharmacological Investigations of Calendula arvensis L.: A Comprehensive Review by Aya Khouchlaa, Aicha El Baaboua, Hamza El Moudden, Fatima Lakhdar, Saad Bakrim, Naoual El Menyiy, Omar Belmehdi, Hicham Harhar, Nasreddine El Omari, Abdelaali Balahbib, Moon Nyeo Park, Gokhan Zengin, Bonglee Kim, Abdelhakim Bouyahya

“…Nevertheless, pharmacokinetic validation and toxicological examinations are required to detect any possible toxicity for future clinical trials.…”
Get full text

Structural and Functional Annotation of Hypothetical Proteins of O139 by Md. Saiful Islam, Shah Md. Shahik, Md. Sohel, Noman I. A. Patwary, Md. Anayet Hasan

“…Structural prediction of these proteins and detection of binding sites from this study would indicate a potential target aiding docking studies for therapeutic designing against cholera.…”
Get full text

Clinical diagnosis of Q fever by targeted next-generation sequencing for identification of Coxiella burnetii by Shaohua Zhan, Haoyuan Jin, Hanbing Ji, Xin Hou, Jing Li, Ye Zhang, Jiajia Zheng, Liyan Cui

“…Conclusions tNGS is a promising and significant tool for rapidly detecting C. burnetii infection.…”
Get full text

Nu—A Marine Life Monitoring and Exploration Submarine System by Ali A. M. R. Behiry, Tarek Dafar, Ahmed E. M. Hassan, Faisal Hassan, Abdullah AlGohary, Mounib Khanafer

“…Nu’s functionality was evaluated in a controlled 2.5-m-deep body of water, focusing on connectivity, maneuverability, and fish identification accuracy. The fish detection algorithm achieved an average precision of 60% in identifying fish presence, while the classification model achieved 97% precision in assigning species labels, with unknown species flagged correctly. …”
Get full text