Exendin-4 Protects MIN6 Cells from t-BHP-Induced Apoptosis via IRE1-JNK-Caspase-3 Signaling by Wen-Jia Chen, Lin-Xi Wang, Yan-Ping Wang, Zhou Chen, Xiao-Ying Liu, Xiao-Hong Liu, Li-Bin Liu

“…Expression of P-IRE1α, IRE1α, C-Jun N-terminal kinase (JNK), P-JNK, C-JUN, and P-C-JUN was detected by western blotting. Results. Exendin-4 was found to inhibit t-BHP-induced apoptosis in pancreatic β-cells by downregulating caspase-3 activity. …”
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Analysis of Five Earthy-Musty Odorants in Environmental Water by HS-SPME/GC-MS by Zhen Ding, Shifu Peng, Weiwen Xia, Hao Zheng, Xiaodong Chen, Lihong Yin

“…Based on the simple modification of original magnetic stirrer purchased from CORNING (USA), the five target compounds can be separated within 23 min, and the calibration curves show good linearity with a correlation coefficient above 0.999 (levels = 5). The limits of detection (LOD) are all below 1.3 ng L−1, and the relative standard deviation (%RSD) is between 4.4% and 9.9% (n = 7) and recoveries of the analytes from water samples are between 86.2% and 112.3%. …”
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LiDAR and IMU Tightly Coupled Localization System Based on Ground Constraint in Flat Scenario by Man Yu, Keyang Gong, Weihua Zhao, Rui Liu

“…Verifications based on KITTI dataset show that the height positioning accuracy will be improved through introducing ground constraint factor and loop detection factor. Real vehicle tests indicate that the proposed algorithm has better height positioning accuracy and better robustness compared with the LeGO-LOAM algorithm.…”
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Microarrays as Model Biosensor Platforms to Investigate the Structure and Affinity of Aptamers by Jennifer A. Martin, Yaroslav Chushak, Jorge L. Chávez, Joshua A. Hagen, Nancy Kelley-Loughnane

“…An indirect labeling method, where the target was labeled with a biotin followed by a brief Cy3-streptavidin incubation, provided a higher signal-to-noise ratio and over two orders of magnitude improvement in limit of detection, compared to direct Cy3-protein labeling. …”
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Evaluating Company’s Readiness for Adopting Product Line Engineering: a Second Evaluation Round by Luisa Rincón, Raúl Mazo, Camille Salinesi

“…The results obtained from the evaluation resulted in modifications to the framework content, mainly to simplify the statements and eliminate redundant elements. Also, we detected new functionalities and modifications that we expect to be resolved in the following evaluation iterations. …”
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A prebiotic intervention improves mood in everyday life in healthy women but not in men: Exploratory results from a larger double-blind placebo controlled cross-over study by Koen Hogenelst, Tanja Krone, Boukje Eveleens Maarse, Ines Warnke, Jessica Snabel, Tim J. van den Broek, Frank Schuren, Matthijs Moerland, Femke P.M. Hoevenaars

“…Overall, our findings may stimulate more targeted gut-microbiome interventions and detection of its mental health effects in real life.…”
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Asymptomatic cholecystitis and its controversial issues in biliary surgery by Sergey Yurievich Muraviev, Evgeniy Alexandrovich Tarabrin, Alexey Leonidovich Shestakov, Irina Alexandrovna Tarasova, Ivan Alexandrovich Markov, Vadim Sergeevich Razumovsky, Anna Victorovna Ananichuk, Andrey Pavlovich Fabrika, Valeria Alexandrovna Stener, Mehrshad Ebrahimnezhad, Denis Vasilievich Orlushin, Anna Nikolaevna Zavyalova

“…That is why most cases of postcholecystectomy syndrome occur in patients operated on for asymptomatic cholecystitis.The unwillingness to discover the secret of stone formation and asymptomatic cholecystitis in humans when concretions in the gallbladder are detected without reference to surgery, to indicate the trajectory of the examination, leads to a number of tactical errors, preserving the risk of PES, and erasing practical recommendations for the management of such patients. …”
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New linearization and reweighting for simulations of string sigma-model on the lattice by L. Bianchi, V. Forini, B. Leder, P. Töpfer, E. Vescovi

“…Abstract We study the discretized worldsheet of Type IIB strings in the Gubser-Klebanov-Polyakov background in a new setup, which eliminates a complex phase previously detected in the fermionic determinant. A sign ambiguity remains, which a study of the fermionic spectrum shows to be related to Yukawa-like terms, including those present in the original Lagrangian before the linearization standard in a lattice QFT approach. …”
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Purine-Metabolizing Ectoenzymes Control IL-8 Production in Human Colon HT-29 Cells by Fariborz Bahrami, Filip Kukulski, Joanna Lecka, Alain Tremblay, Julie Pelletier, Liliana Rockenbach, Jean Sévigny

“…The expression of the ectoenzymes was evaluated by RT-PCR, qPCR, and immunoblotting, and their activity was analyzed by RP-HPLC of the products and by detection of Pi produced from the hydrolysis of ATP, ADP, and AMP. …”
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Adjusting Effects of Baicalin for Nuclear Factor-κB and Tumor Necrosis Factor-α on Rats With Caerulein-Induced Acute Pancreatitis by Dongbo Xue, Weihui Zhang, Yingmei Zhang, Haiyang Wang, Biao Zheng, Xingye Shi

“…The mRNA expression of TNF-α was measured with semiquantitative RT-PCR, and activation of NF-κB was detected with flow cytometry assay. It was shown in the results that the expression of TNF-α mRNA, activation of NF-κB, and pathological score of AP group were all obviously higher than those of control group (P<.01). …”
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Intravenous Administration of Bone Marrow-Derived Mesenchymal Stem Cells Induces a Switch from Classical to Atypical Symptoms in Experimental Autoimmune Encephalomyelitis by Mónica Kurte, Javiera Bravo-Alegría, Alexander Torres, Vania Carrasco, Cristina Ibáñez, Ana María Vega-Letter, Catalina Fernández-O’Ryan, Carlos E. Irarrázabal, Fernando E. Figueroa, Rodrigo A. Fuentealba, Claudia Riedel, Flavio Carrión

“…Surprisingly, EAE atypical signs were detected in EAE+MSCpeak and EAE+MSClate mice. However, no correlation was found in Th17/Th1 ratio. …”
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Expression of Potential Dermal Progenitor Cell Markers in the Tumour and Stroma of Skin Adnexal Malignant and Benign Tumours by Sven R. Quist, Maximilian Eckardt, André Kriesche, Harald P. Gollnick

“…To investigate whether markers reported to label dermal progenitor cells are preserved in the tumour including the tumour stroma of skin adnexal tumours, we tested 45 human basal cell carcinomas, including superficial, nodular, adenoid, infiltrating, and sclerosing types, and further 38 human tumours of skin appendages including 13 sebaceous adenomas and carcinomas, 20 eccrine sweat gland tumours, and 5 pilomatricomas, syringomas, and hair follicle tumours for the expression of the potential dermal and epidermal cell markers CRABP1, Nestin, and Ephrin B2 and compared these findings with healthy, age-related human epidermis. We detected that CRABP1, Nestin, and Ephrin B2 are expressed in the intratumoural stroma as well as the tumour invasive front of skin tumours of appendages and BCCs.…”
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NUCB2/Nesfatin-1 Regulation of Chronic Visceral Hyperalgesia by Qiaoyan Gu, Yuan Lei, Jianming Wu, Ting He, Juanjuan Li, Shanshan Song

“…The models were identified by the distension volume threshold to reach abdominal withdraw reflex AWR score=3, histological staining, and myeloperoxidase (MPO) detection. The visceral sensitivity to chronic visceral hyperalgesia was then evaluated. …”
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Myotubularin-Related Phosphatase 3 Promotes Growth of Colorectal Cancer Cells by Bo’an Zheng, Xiaojun Yu, Rui Chai

“…The activation of apoptotic markers, Bad and PARP, was detected using Intracellular Signaling Array. Knockdown of MTMR3 resulted in a significant reduction in cell proliferation in both HCT116 and SW1116 cells. …”
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Effect of Fireworks, Chinese New Year and the COVID-19 Lockdown on Air Pollution and Public Attitudes by Peter Brimblecombe, Yonghang Lai

“…Beijing, where restrictions were less stringent, showed some improvement in air quality, though this is more difficult to detect, even within the 5th Ring Road.…”
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PAUL FEYERABEND ON THE SCIENTIFIC WORLDVIEW: TOWARDS QUESTIONING THE SCIENTIFIC UNIFORMITY by N. I. Petrunok

“…By means of typical political concepts (such as ideology and propaganda) he detected basic objectives of scientists. Our main methodological tools in this research are comparative analyses of the sources and immanent critique of Feyerabend’s arguments. …”
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Pengaruh Metode Pendidikan Sebaya terhadap Tingkat Pengetahuan Tentang Pemeriksaan Payudara Sendiri (SADARI) Pada Remaja Putri Di SMA Negeri 1 Kubu by Ni Putu Eka Wijayanti, Made Ririn Sri Wulandari, Luh Putu Widiastini

“…BSE or breast self-examination is one of the early detection of breast cancer, but awareness of doing BSE is still low. …”
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Prevalence and Factors Associated with Sexually Transmitted Infections among Jimma University Students, Southwest Ethiopia by Rahel Tamrat, Tesfaye Kasa, Zewdineh Sahilemariam, Mulatu Gashaw

“…Standard protocol was followed to detect the etiologies of STI. Data were entered and analyzed using SPSS Version 20. …”
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Tools of preventive police activity in the field of combating cruelty to animals by V. S. Seliukov, А. І. Potikhenskyi

“…It follows that prevention, as the main type of police activity, should be aimed at meeting the needs of society, and not at developing indicators of crime detection. It is noted that the forms and methods of police activity at the current stage of combining theory and practice should be considered as tools of police activity. …”
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Fabrication and Optimization of ChE/ChO/HRP-AuNPs/c-MWCNTs Based Silver Electrode for Determining Total Cholesterol in Serum by Kusum Lata, Vikas Dhull, Vikas Hooda

“…The biosensor shows a broad linear range from 0.5 mg/dL to 250 mg/dL (0.01 mM–5.83 mM) with minimum detection limit being 0.5 mg/dL (0.01 mM). The biosensor showed reusability of more than 45 times and was stable for 60 days. …”
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