Microcephaly protein ANKLE2 promotes Zika virus replication by Adam T. Fishburn, Cole J. Florio, Thomas N. Klaessens, Brian Prince, Neil A. B. Adia, Nicholas J. Lopez, Nitin Sai Beesabathuni, Sydney S. Becker, Liubov Cherkashchenko, Sophia T. Haggard Arcé, Vivian Hoang, Traci N. Shiu, R. Blake Richardson, Matthew J. Evans, Claudia Rückert, Priya S. Shah

“…Our data point to an overall model in which ANKLE2 regulates virus-induced membrane rearrangements to accelerate orthoflavivirus replication and avoid immune detection. However, ANKLE2’s unique role in ZIKV NS4A-induced microcephaly is a consequence of ZIKV infection of important developing tissues in which ANKLE2 has essential roles.…”
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Fluoride in drinking water and associated non-carcinogenic health risk in Inner Mongolia Autonomous Region, 2022: a monitoring data analysis by Wenqian ZHANG, Jiake ZHU, Wenyu ZHANG, Xinrui JIA, Xuanzhi YUE, Huan LI, Duoduo WU, Yuhan QIN, Yaochun FAN

“…ResultsFor all samples, the fluoride concentration (mg/L) ranged from not detected to 8.830, with a median of 0.500 and a 25th/75th percentile of 0.300/0.750; the fluoride content in 91.64% of the samples was within the limit (≤ 1.0 mg/L) of the National Sanitary Standards for Drinking Water (GB 5749 – 2006). …”
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Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease by Zhen Zhu, Guangxin Luan, Song Wu, Yiyi Song, Shuang Shen, Kaiyue Wu, Shengnan Qian, Weiping Jia, Jun Yin, Tao Ren, Jianping Ye, Li Wei

“…Various fluorescent probes and energy detector are used to detect mitochondrial apoptosis, ROS, and respiration of mitochondrion. …”
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Effects of landslide hazards on quality of stream water and sediments by O. Phewnil, T. Pattamapitoon, N. Semvimol, W. Wararam, K. Duangmal, A. Intaraksa, K. Chunkao, P. Maskulrath, S. Hanthayung, P. Wichittrakarn

“…The insight gained from these collection efforts elucidated the dynamics of landslide impacts at the spatial scale for the two watersheds.FINDINGS: Most water samples met Thai surface water quality standard for various parameters; however, microbial contamination of the water samples attributed to community activities along stream banks was detected. Notably, arsenic was consistently detected in upland soil, stream water, and sediment samples. …”
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Construction of feature selection and efficacy prediction model for transformation therapy of locally advanced pancreatic cancer based on CT, 18F-FDG PET/CT, DNA mutation, and CA19... by Liang Qi, Xiang Li, Jiayao Ni, Yali Du, Qing Gu, Baorui Liu, Jian He, Juan Du

“…Among them, 65 patients had efficacy evaluation results after 4 treatment cycles, 54 patients had complete baseline PET/CT images, 51 patients had complete DNA mutation detection results, and 34 patients had both complete PET/CT images and DNA mutation detection results. …”
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Comprehensive Evaluation of GPM-IMERG, CMORPH, and TMPA Precipitation Products with Gauged Rainfall over Mainland China by Guanghua Wei, Haishen Lü, Wade T. Crow, Yonghua Zhu, Jianqun Wang, Jianbin Su

“…However, all four products are unreliable over XJ at both an annual and seasonal scale. (4) Across all products, TRMM 3B42 best reproduces the probability density function (PDF) of daily precipitation intensity. (5) According to the categorical verification technique in this study, both IMERG products yield better results for the detection of precipitation events on the basis of probability of detection (POD) and critical success index (CSI) categorical evaluations compared to TRMM 3B42 and CMORPH-CRT over China and across most of the subregions. …”
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Features of expression of immunohistochemical markers in local and generalized clear cell kidney cancer by E. M. Frantsiyants, A. N. Shevchenko, E. A. Dzhenkova, N. S. Karnaukhov, T. A. Gudtskova, A. A. Breus, E. V. Filatova, D. A. Shvyrev

“…Dewaxing and restoration of antigenic activity of the material was carried out in the RT module (Thermo Fisher Scientific) using Tris buffer pH=9, for 20 minutes at 98 °C. the Formulation of the IGC reaction was carried out in the immunohistostainer «Autostainer 480S» (Thermo Fisher Scientific). Used system detection UltraVision Quanto Detection System (Thermo Fisher Scientific), and the Chromogen DAB. …”
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Treatment Efficiency by means of a Nonthermal Plasma Combined with Heterogeneous Catalysis of Odoriferous Volatile Organic Compounds Emissions from the Thermal Drying of Landfill L... by Daniel Almarcha, Manuel Almarcha, Elena Jimenez-Coloma, Laura Vidal, Montserrat Puigcercós, Iban Barrutiabengoa

“…Compounds belonging to the following families have been detected in the samples: organic acids, alcohols, ketones, aldehydes, pyrazines, and reduced sulphur compounds, among others. …”
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Future Changes in Surface Runoff over Korea Projected by a Regional Climate Model under A1B Scenario by Ji-Woo Lee, Suryun Ham, Song-You Hong, Kei Yoshimura, Minsu Joh

“…The variability of runoff is increased in summer; moreover, the strengthened possibility of extreme occurrence is detected in the future climate. This study indicates that future climate projection, including surface runoff and its variability over Korea, can be adequately addressed on the RMP testbed. …”
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Unveiling the dual nature of Lactobacillus: from cariogenic threat to probiotic protector—a critical review with bibliometric analysis by Di Fu, Xingyue Shu, Lin Yao, Ge Zhou, Mengzhen Ji, Ga Liao, Yunwo Zhu, Ling Zou

“…“Dental caries”, “Streptococcus mutans”, “Lactobacilli”, “Probiotics”, and “Children” have been commonly used as keywords.DiscussionBased on bibliometric analysis, this study reviews the relationship between lactobacilli and dental caries, emphasizing their dual roles. The detection rate of lactobacilli is closely associated with the incidence and severity of dental caries. …”
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Features of classification and examination of butter and spreads by N. V. Kryvоruchkо, T. S. Kyrychenkо

“…The main identification tasks in the commodity expertise of these products are: product composition, detection of impurities, organoleptic characteristics, texture and consistency, chemical analysis, comparison with standards, determination of product origin. …”
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Genotypes and phenotypes of neurofibromatosis type 1 patients in Japan: A Hereditary Tumor Cohort Study by Mashu Futagawa, Tetsuya Okazaki, Eiji Nakata, Chika Fukano, Risa Osumi, Fumino Kato, Yusaku Urakawa, Hideki Yamamoto, Toshifumi Ozaki, Akira Hirasawa

“…Germline pathogenic variants were detected in 36 patients (81.8%), and 20.7% of the variants were novel. …”
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How to measure consumer's inconsistency in sensory testing? by László Sipos, Kolos Csaba Ágoston, Péter Biró, Sándor Bozóki, László Csató

“…Therefore, we provide a statistical framework to rank assessors and attributes according to the level of inconsistency, as well as to identify inconsistent assessors, based on Kendall rank correlation coefficients. The detection of (in)consistency requires evaluations on two connected scales. …”
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Diagnostic Power of Vascular Endothelial Growth Factor and Macrophage Colony-Stimulating Factor in Breast Cancer Patients Based on ROC Analysis by Monika Zajkowska, Edyta Katarzyna Głażewska, Grażyna Ewa Będkowska, Przemysław Chorąży, Maciej Szmitkowski, Sławomir Ławicki

“…These results indicate the usefulness and high diagnostic power of VEGF in the detection of BC. Also, it occurred to be the best candidate for cancer diagnostics in stages I and II of BC and in the differentiation between BC and benign cases.…”
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Evaluation of Histopathological Changes in Control Biopsies Which Taken 48 Sessions after NBUVB Phototherapy for Early-Stage Mycosis Fungoides by Ebru Zemheri, Seyma Ozkanli, Ilkin Zindanci, Serkan Senol, Ozge Akbulak, Elvan Turfanda, Mehtap Toprak, Duygu Kosemetin, Abdullah Aydin

“…Comparing by response, normalization of stratum corneum and epidermis, orthohyperkeratosis, decrease in linearly arranged cells, the lichenoid/patchy lichenoid infiltration, the loss of inflammation were statistically significant in responders group. Conclusion. We detected a significant decrease in linearly arranged cells after phototherapy, indicating that it is an “important diagnostic parameter" in evaluation of therapeutic response.…”
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Occurrence and Behavior Analysis of <i>Duponchelia fovealis</i> on Strawberry Plants: Insights for Integrated Pest Management by Rodrimar Barboza Gonçalves, Maria Aparecida Cassilha Zawadneak, Taciana Melissa de Azevedo Kuhn, Thales Fernando Moreno Gulinelli, Ida Chapaval Pimentel, Alex Sandro Poltronieri, Joatan Machado da Rosa, José Manuel Mirás-Avalos, Emily Silva Araujo

“…The sprayed insecticide remained in the upper and middle thirds of the strawberry plant canopy, not reaching the organs where <i>D. fovealis</i> larvae were mainly detected. This study provides useful information on the cryptic habit of this pest that may help in designing efficient monitoring and control strategies.…”
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A Newborn with Cleft Palate Associated with PTEN Hamartoma Tumor Syndrome by Ulf Nestler, Daniel Gräfe, Vincent Strehlow, Robin-Tobias Jauss, Andreas Merkenschlager, Annika Schönfeld, Florian Wilhelmy

“…Since the correlation between phenotype and genotype is weak, and the penetrance is age-dependent, this poses the question of the appropriate timing of potentially invasive and burdensome examinations for early cancer detection. <b>Case</b>: The present report describes an infant with cleft palate associated with PHTS, a rare occurrence, though the initial report of Cowden syndrome already pointed to oromaxillofacial abnormalities. …”
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A versatile platform based on matrix metalloproteinase-sensitive peptides for novel diagnostic and therapeutic strategies in arthritis by Mingyang Li, Tao Deng, Quan Chen, Shenghu Jiang, Hang Li, Jiayi Li, Shenglan You, Hui-qi Xie, Bin Shen

“…Specifically, the ultra-sensitive MSP diagnostic probes could significantly advance the early diagnosis and detection of osteoarthritis (OA), while MSP-based drug carriers for rheumatoid arthritis (RA) can intelligently release anti-inflammatory drugs effectively during flare-ups, or even before symptoms manifest. …”
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Uncovering a novel SERPING1 pathogenic variant: insights into the aggregation of C1-INH in hereditary angioedema by Lingxi Jiang, Chao Dai, Suyang Duan, Tingting Wang, Chunbao Xie, Luhan Zhang, Zimeng Ye, Xiumei Ma, Yi Shi

“…Conclusion Based on our findings, we propose that the detection of intracellular Ca2+ concentration could serve as a valuable biomarker for predicting acute attacks of HAE in patients. …”
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White Mold: A Global Threat to Crops and Key Strategies for Its Sustainable Management by Md. Motaher Hossain, Farjana Sultana, Md. Tanbir Rubayet, Sabia Khan, Mahabuba Mostafa, Nusrat Jahan Mishu, Md. Abdullah Al Sabbir, Nabela Akter, Ahmad Kabir, Mohammad Golam Mostofa

“…This review discusses the latest insights into the biology, epidemiology, infection mechanisms, and early detection of white mold. This review also aims to provide comprehensive guidelines for sustainable management of this destructive disease while reducing the use of excessive pesticides in crop fields.…”
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