Acidovorax temperans skews neutrophil maturation and polarizes Th17 cells to promote lung adenocarcinoma development by Joshua K. Stone, Natalia von Muhlinen, Chenran Zhang, Ana I. Robles, Amy L. Flis, Eleazar Vega-Valle, Akihiko Miyanaga, Masaru Matsumoto, K. Leigh Greathouse, Tomer Cooks, Giorgio Trinchieri, Curtis C. Harris

“…Neutrophil to monocyte and macrophage signaling upregulated MHC II to activate CD4+ T cells, polarizing them to an IL-17A+ phenotype detectable in CD4+ and γδ populations (T17). These T17 cells shared a common gene expression program predictive of poor survival in human LUAD. …”
Get full text

Elevated Troponin Serum Levels in Adult Onset Still’s Disease by Carlo Umberto Manzini, Lucio Brugioni, Michele Colaci, Maurizio Tognetti, Amelia Spinella, Marco Sebastiani, Dilia Giuggioli, Clodoveo Ferri

“…In the case of abrupt, recent onset AOSD, it could be particularly difficult to make the differential diagnosis and in particular to early detect the possible heart involvement. This latter event is suggested by the clinical history of the four patients described here, incidentally observed at our emergency room. …”
Get full text

Tiltmeter Data Revealing Transient Magma Viscosity Changes During Eruptions by David Gomez-Ortiz, Jose Arnoso, Silvia Martín-Velázquez, Tomás Martín-Crespo, Fuensanta González Montesinos, Emilio Vélez, Maite Benavent

“…Volcanic processes related to episodes of inflation, dike propagation, effusive activity, etc., can be detected by continuous surface tilt measurements. The interpretation of these measurements helps comprehend medium-to-short-term precursors of volcanic eruptions or establishes early warning alerts. …”
Get full text

Ecotoxicological evaluation in aquaculture in state park Serra do Mar-SP, Nucleo Itariru by Bruno Galvão de Campos, Denis Moledo de Souza Abessa, Mauro Cornacchioni Lopes, Newton José Rodrigues da Silva

“…Acute toxicity was assessed using tests with Daphnia similis, following ABNT NBR 12713/2005 protocol, and the results were analyzed by Student’s t’test. Toxicity was detected only in the first two sectors from the farming system, suggesting the release of contaminants upstream, which were confirmed after interviews with local producers. …”
Get full text

Transcriptomic and physiological analyses reveal that cytokinin is involved in the compound leaf development of alfalfa by Hongyao Mei, Jiajun Yan, Xuexin Jia, Weilin Wang, Shuangshuang Li, Ruiqi Sun, Hongjiao Jiang, Lijun Xie, Chuanen Zhou, Shiqie Bai, Lu Han

“…Both exogenous treatment and endogenous CK content detection indicated that cytokinin played a key role in the development of the alfalfa compound leaf. …”
Get full text

Investigation of Microstructural Damage in Ultrahigh-Performance Concrete under Freezing-Thawing Action by Chunping Gu, Wei Sun, Liping Guo, Qiannan Wang, Jintao Liu, Yang Yang, Tao Shi

“…Mercury intrusion porosimetry (MIP), scanning electron microscopy (SEM), and X-ray computed tomography (X-ray CT) were applied to detect the microstructure of the UHPC matrix before and after the freezing-thawing tests. …”
Get full text

Characterization of Progenitor Cells during Canine Retinal Development by Mallely Ávila-García, Gustavo García-Sánchez, Esmeralda Lira-Romero, Norma Moreno-Mendoza

“…We identify the presence of progenitor cells during retinal development in the dog, as this species represents a natural model for studying several breed-specific degenerative retinal disorders. Antibodies to detected progenitor cells (Pax6, C-kit, and nestin) and ganglion cells (BDNF, Brn3a, and Thy1) were used in combination with H3 for the purpose of identifying proliferating cells. …”
Get full text

An Optimized Collision Avoidance Decision-Making System for Autonomous Ships under Human-Machine Cooperation Situations by Xiaolie Wu, Kezhong Liu, Jinfen Zhang, Zhitao Yuan, Jiongjiong Liu, Qing Yu

“…Previous studies aim to propose fully autonomous system on collision avoidance decisions and operations, either focus on supporting conflict detection or providing with collision avoidance decisions. …”
Get full text

A Very Rare Case: HPV-Negative Vulvar Cancer in an Adolescent by Ilker Kahramanoglu, Hasan Turan, Yahya Ozgun Oner, Tugan Bese, Sennur Ilvan, Macit Arvas, Fuat Demirkiran

“…Vulvar carcinoma in very young women may develop without any predisposing factor. Early detection will result in better survival. So, there should be a high index of suspicion when a vulvar lesion is seen, even if the patient falls below the typical age range and does not carry any well-known risk factors such as HPV infection and immunodeficiency.…”
Get full text

Recent advances in bio-integrated electrochemical sensors for neuroengineering by Shulin Chen, Tzu-Li Liu, Yizhen Jia, Jinghua Li

“…Detecting and diagnosing neurological diseases in modern healthcare presents substantial challenges that directly impact patient outcomes. …”
Get full text

Cystic Form of Duodenal Dystrophy (Clinical Case) by D. E. Okonskaya, Kh. H. Ayvazyan, Yu. A. Stepanova, A. V. Zhao, E. A. Sokolova

“…With the help of computed tomography, the diagnosis was established, the tumor process was rejected, and chronic pancreatitis was detected in the orthotopic pancreas. Due to the presence of changes in the main pancreas, the patient underwent pancreatoduodenal resection. …”
Get full text

Simultaneous Determination of Lamivudine, Zidovudine and Abacavir in Tablet Dosage Forms by RP HPLC Method by D. Anantha Kumar, G. Srinivasa Rao, J. V. L. N. Seshagiri Rao

“…Chromatography was carried out on a HiQ Sil C 18 V column using a mobile phase consisting of 0.01 M potassium dihydrogen ortho-phosphate (pH 3.0) and methanol (55:45 v/v) at a flow rate of 0.8 mL/min. The detection was made at 272 nm and stavudine was used as the internal standard for this study. …”
Get full text

Spat efficiency of the smooth scallop Flexopecten glaber in the Aegean Sea, Türkiye by Yigitkurt Selcuk, Kırtık Ali, Kurtay Evrim, Ugur Sinem, Durmaz Yasar

“…Throughout the study, the number of F. glaber on the collectors was 270.33 ± 43.54 spat m−2 and 145.66 ± 18.03 spat m−2 were detected on the bottom collectors. A statistically significant difference was found between the growth of the spat attached to the surface and bottom collectors (p < 0.05).…”
Get full text

Differentiation and characterization of volatile compounds in five common milk powders using HS-GC-IMS, HS-SPME-GC–MS, and multivariate statistical approaches by Yaxi Zhou, Diandian Wang, Jian Zhao, Yu Guo, Wenjie Yan

“…These results underscored the potential of utilizing these combined techniques for quick flavor analysis and detecting adulteration in milk powder.…”
Get full text

Intermittent behavior near the boundary of generalized synchronization in unidirectionally coupled time-delayed systems by Moskalenko, Olga Igorevna, Khanadeev, V. A.

“…It has been found that the multistability measure can be used to detect the generalized synchronization in time-delayed systems. …”
Get full text

Exploring a Design of Landslide Monitoring System by Rahat Khan, Suhail Yousaf, Abdul Haseeb, Muhammad Irfan Uddin

“…Through extensive simulations, the performance of various landslide prediction and detection models has been evaluated. By and large, the study lets a significant insight into landslide monitoring before implementing a parameterized application for real-world deployment.…”
Get full text

The Effect of Irisin as a Metabolic Regulator and Its Therapeutic Potential for Obesity by Hui Li, Fang Wang, Mu Yang, Jiao Sun, Yi Zhao, Dongqi Tang

“…Finally, the review discussed the existing unresolved issues and controversies about irisin, including the transcription of the irisin precursor FNDC5 gene in humans, the cleavage site of the yet unknown proteolytic enzyme that cleaves irisin from FNDC5, and the reliability of irisin levels measured with available detection methods.…”
Get full text

Combined treatment of an infected paraurethral cyst by A. A. Kostin, L. V. Shaplygin, N. G. Kulchenkо, A. Mansur

“…In the postoperative period, the patient also received antimicrobial therapy. We did not detect a recurrence of the paraurethral cyst, observing the patient for 1 year. …”
Get full text

Effect of Ultrafine Powderization and Solid Dispersion Formation via Hot-Melt Extrusion on Antioxidant, Anti-Inflammatory, and the Human Kv1.3 Channel Inhibitory Activities of Ange... by Yunyao Jiang, Jingpei Piao, Nan Liu, Jincai Hou, Jianxun Liu, Weicheng Hu

“…The potential antioxidant and anti-inflammatory activities of AGN with a different process were compared, and the effect on the human Kv1.3 potassium channel was detected. The process of ultrafine powderization on AGN significantly increased the total phenolic and flavonoid contents, antioxidant activity, and DNA damage protective effect. …”
Get full text

Сurrent state of clinical significance of early kidney injury markers by D. N. Khotko, A. I. Khotko, A. I. Tarasenko, A. O. Efimova

“…Today it is most relevant to conduct the search for biomarkers of acute and chronic renal lesions at patients with urolithiasis to detect pathological changes in the kidneys and to determine their nature at an early stage of diagnosis.Improved diagnostic techniques destined to provide a detailed picture of the development of the pathological process in patients with urolithiasis will make it possible to prevent renal failure development at an early stage in this category of patients.…”
Get full text