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8741
Identification of potential druggable targets for endometriosis through Mendelian randomization analysis
Published 2025-01-01“…We applied a range of validation techniques, including reverse causality detection, phenotype scanning, Bayesian co-localization (BC) analysis, and external validations to substantiate our findings. …”
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8742
Insights from serial cardiovascular magnetic resonance imaging show early progress in diastolic dysfunction relates to impaired right ventricular deformation
Published 2025-02-01“…We hypothesized that serial real-time cardiovascular magnetic resonance (CMR) imaging at rest and during exercise-stress may detect early progress in pathophysiological alterations in HFpEF. …”
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8743
Genetic determinants of silver nanoparticle resistance and the impact of gamma irradiation on nanoparticle stability
Published 2025-01-01“…Whole genome sequencing (WGS) was performed on selected susceptible isolates of gram-positive Staphylococcus lentus (St.L.1), gram-negative Klebsiella pneumonia (KP.1), and their resistant isolates St.L_R.Ag and KP_R.Ag to detect the genomic changes and mutations. Conclusions For the detection of single-nucleotide polymorphisms (SNPs) and the identification of all variants (SNPs, insertions, and deletions) in our isolates, the Variation Analysis Service tool available in the Bacterial and Viral Bioinformatics Resource Center (BV-BRC) was used. …”
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8744
Serum β2-MG, sCHE, and PSGL-1 Expression in Patients with Esophageal Cancer and Their Association with Postoperative Lung Infection After Mediastinoscopy
Published 2025-01-01“…An automatic microbiological identification system was used to detect the pathogenic bacteria of lung infection. …”
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8745
Do Activity Sensors Identify Physiological, Clinical and Behavioural Changes in Laying Hens Exposed to a Vaccine Challenge?
Published 2025-01-01“…This study aimed to identify if sensor technology could be used to detect sickness-type signs (caused by a live vaccine) in laying hens compared to physiological and clinical sign scoring and behaviour observation. …”
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8746
Accuracy of screening tests for cervical precancer in women living with HIV in low-resource settings: a paired prospective study in Lusaka, Zambia
Published 2024-07-01“…The index tests were high-risk human papillomavirus detection (hrHPV, Xpert HPV, Cepheid), portable colposcopy (Gynocular, Gynius) and visual inspection with acetic acid (VIA). …”
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8747
Genetic diversity and transmission pattern of multidrug-resistant tuberculosis based on whole-genome sequencing in Wuhan, China
Published 2025-01-01“…Additional mutations were detected in fabG1 c-15C > T (42.86%, ethionamide) and thyX c-16C > T (21.43%, p-aminosalicylic acid). …”
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8748
FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis
Published 2025-02-01“…Assessments encompassed histopathology, ELISA for cytokine detection, IHC and Western blot for protein expression analysis, and qRT-PCR for gene expression quantification. …”
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8749
Diagnostic performance of CT for extrarenal fat invasion in renal cell carcinoma: a meta-analysis and systematic review
Published 2025-01-01“…Conclusion CT has the ability to detect the PFI and RSFI in patients with RCC. However, the diagnostic performance of CT has suffered from the limitation of slightly lower accuracy, resulting from the low positive sample in the current studies. …”
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8750
Increased aqueous humor levels of endothelin-1 in patients with open angle glaucoma
Published 2025-01-01“…No significant difference in aqueous ET-1 was detected in the XFG cohort (6.2 ± 4.5 pg/mL; p = 0.230) compared to the control. …”
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8751
Antibiotic Resistance and Molecular Epidemiological Characteristics of Streptococcus agalactiae Isolated from Pregnant Women in Guangzhou, South China
Published 2020-01-01“…Seventy-two S. agalactiae strains, collected from pregnant women, were subjected to antibiotic susceptibility tests; then, the screened erythromycin and clindamycin nonsusceptible isolates were used for macrolides and clindamycin resistance genes detection, respectively. Detection of resistance genes, serotyping, and determination of virulence genes were performed by polymerase chain reaction. …”
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8752
Effectiveness of Continuous Glucose Monitoring on Short-Term, In-Hospital Mortality Among Frail and Critically Ill Patients With COVID-19: Randomized Controlled Trial
Published 2025-02-01“…A total of 207 hypoglycemia events (<3.9 mmol/L) was detected, with 43 in the isCGM group and 164 in the POCT group (P<.001). …”
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8753
Application of N-Acetyl-Glucosaminil-N-Acetyl-Muramyl Dipeptide during Triple Component Anti-Helicobacter Pylori Therapy in the Period of Coronavirus Infection COVID-19
Published 2023-08-01“…H. pylori in the gastric mucosa was detected by a morphological method and a rapid urease test before treatment and 6-8 weeks after the end of treatment and the withdrawal of all drugs. …”
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8754
Hunting for gravity waves in non-orographic winter storms using 3+ years of regional surface air pressure network and radar observations
Published 2025-02-01“…Reanalysis model output and operational weather observations provided environmental context for each gravity wave event. We detected 33 pressure wave events across 40 months of data; of these events, 23 were gravity waves, whereas the rest were frontal passages, outflow boundary passages, or a wake low. …”
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8755
An exploratory study on the differential diagnostic indicators between adult systemic EBV-positive T-cell lymphoproliferative disorders and angioimmunoblastic T-cell lymphoma with...
Published 2025-01-01“…Results 7 cases of adult EBV+ T-LPD: all cases had no more than 1 T follicular helper (THF) marker was expressed, and there were significantly more EBER+/CD3 + cells than EBER+/CD20 + cells; 5 cases had mutation detection results, in which only 1 had the characteristic KMT2D mutation, 2 had TET2 mutations, and no common mutations such as DDX3X were detected.16 cases of AITL with multiple EBV infections: all cases were found to express at least 2 TFH markers, with 87% of them expressing at least 3 TFH markers., and had significantly more EBER+/CD20 + cells than EBER+/CD3 + cells; 4 cases had mutation test results, with mutated high-frequency genes being TET2 (100%, and all of them had 2 or more TET2 mutations) and RHOA G17V (100%), DNMT3A mutation occurred in 2 cases (50%), and IDH2 R172 mutation occurred in 1 case (25%). …”
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8756
Screening of West Siberian patients with primary congenital glaucoma for CYP1B1 gene mutations
Published 2020-12-01“…The latter can cause a frame shift, changed amino acid composition, and a formation of truncated in the protein. None of the detected mutations were found in the control sample of ophthalmologically examined individuals without PCG (100 people). …”
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8757
Vermicomposting of coir pith and cow manure: Influence of initial total phenolic content on earthworms’ performance
Published 2024-03-01“…By the end of vermicomposting, almost all of phenolics present in cow manure disappeared while those in coir pith remained intact, albeit, reduced in concentrations. 4-hydroxybenzoic acid and p-coumaric acid were detected in all treatments. Disappearance of 4.90 and 6.35 minute-peaks was observed with T0, T1 and T2 whilst a new phenolic (5.30 minute-peak) was detected only in T1 indicating the better degradation of phenolic compounds. …”
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8758
Consequences of insecticide overuse in Hungary: assessment of pyrethroid resistance in Culex pipiens and Aedes albopictus mosquitoes
Published 2025-01-01“…Results In Cx. pipiens, the kdr mutation was detected across all five collection sites, with resistance allele frequencies ranging from 18.1% to 36.3%. …”
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8759
Virulence potential of faecal <i>Escherichia coli</i> strains isolated from healthy cows and calves on farms in Perm Krai
Published 2022-09-01“…With PCR, the blaTEM, blaSHV, and blaCTX-M genes were detected in 100, 31.6, and 26.3 %, respectively, of strains resistant to at least one of the beta-lactam antibiotics. …”
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8760
Seroprevalence characteristics of hepatitis E virus among blood donors infected with hepatitis B virus
Published 2025-01-01“…Commercially available enzyme-linked immunosorbent assays (ELISA) were used for the detection of anti-HEV IgG, anti-HEV IgM and HEV antigen (Ag). …”
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