Selective Serotonin Reuptake Inhibitors: Antimicrobial Activity Against ESKAPEE Bacteria and Mechanisms of Action by Thiago Hideo Endo, Mariana Homem de Mello Santos, Sara Scandorieiro, Bruna Carolina Gonçalves, Eliana Carolina Vespero, Márcia Regina Eches Perugini, Wander Rogério Pavanelli, Gerson Nakazato, Renata Katsuko Takayama Kobayashi

“…Regarding their mechanisms of action as antibacterials, for the first time, increased membrane permeability was detected, as evidenced by heightened dye absorption, along with the increased presence of total proteins and dsDNA in the extracellular medium of <i>Escherichia coli</i> ATCC2 25922 and <i>Staphylococcus aureus</i> ATCC 25923, and oxidative stress was also detected in bacteria treated with sertraline and paroxetine, with reduced efficiency observed in the presence of antioxidants and higher levels of oxygen-reactive species evidenced by their reaction with 6-carboxy-2′,7′-dichlorodihydrofluorescein diacetate. …”
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Diagnosis and Treatment of Gastroesophageal Reflux Disease (Clinical Guidelines of the Russian Gastroenterological Association, Russian Scientific Medical Society of Internal Medic... by V. T. Ivashkin, A. S. Trukhmanov, I. V. Maev, O. M. Drapkina, M. A. Livzan, A. I. Martynov, T. L. Lapina, A. V. Paraskevova, D. N. Andreev, O. P. Alexeeva, S. A. Alekseenko, A. Yu. Baranovsky, O. V. Zayratyants, O. Yu. Zolnikova, O. B. Dronova, I. L. Kliaritskaia, N. V. Korochanskaya, Yu. A. Kucheryavyy, S. N. Mammaev, M. F. Osipenko, S. S. Pirogov, E. A. Poluektova, D. E. Rumyantseva, R. G. Sayfutdinov, O. A. Storonova, Yu. P. Uspenskiy, I. B. Khlynov, V. V. Tsukanov, A. A. Sheptulin

“…The diagnosis of GERD is established on the basis of anamnestic data, instrumental examination (detection of reflux esophagitis during upper gastrointestinal endoscopy, detection of pathological gastroesophageal reflux with 24-hour pH-metry or/and 24-hour pH-impedance monitoring). …”
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Metagenomic analysis of gut microbiota diversity in poultry before and after antibiotic administration by O. V. Prasolova, N. I. Malik, I. A. Timofeeva, N. A. Kirsanova, E. V. Krylova, E. V. Malik, I. A. Rusanov, N. A. Chupakhina

“…Firmicutes and Bacteroidota species were predominantly detected in the chick microbiota during antibiotic administration and after its withdrawal. …”
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Exosomal PVRL4 Promotes Lung Adenocarcinoma Progression by Enhancing the Generation of Myeloid‐Derived Suppressor Cell‐Secreted TGF‐β1 by Yahai Liang, Jinmei Li, Lihua Zhang, Jinling Zhou, Meilian Liu, Xiaoxia Peng, Weizhen Zheng, Zhennan Lai

“…Here, the precise functions and the relationship between PVRL4 and MDSCs in lung adenocarcinoma (LUAD) progression were investigated. Methods Detection of levels of mRNAs and proteins was conducted using qRT‐PCR and western blotting. …”
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Dynamics of retinal changes in early-stage Parkinson’s disease by Ane Murueta-Goyena, Sara Teijeira-Portas, Elisa Blanco Martín, Raquel Vázquez-Picón, Blanca Ruiz Bajo, Jone Bocos, Jorge Sánchez-Molina, Patricia Alves Dias, Ioana Croitoru, Iñaki Rodríguez Agirretxe, Rocío Del Pino, Marian Acera, Beatriz Tijero, Oihane Sáez-Atxukarro, David Romero-Bascones, Juan Carlos Gómez-Esteban, Javier Aritz Urcola, Javier Ruiz Martínez, Iñigo Gabilondo

“…However, the macular region shows complex and variable dynamics among PD patients, but these changes precede detectable progression in clinical scales.…”
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The Reduced Expression of EOLA1 May Be Related to Refractory Diabetic Foot Ulcer by Mingxia Wu, Weiling Leng, Hang Pan, Xiaotian Lei, Liu Chen, Xinshou Ouyang, Ziwen Liang

“…The relevant clinical data of patients were collected, and the skin tissues around the ulcer were used for immunofluorescence detection and immunohistochemical staining to observe inflammation. …”
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Occupational exposure to flame retardants following production replacement and their effect on thyroid function indicators by Ling Meng, Tingting Guo, Yizhi Liu, Han Wu, Kang An, Xizhu Xu, Yuancheng Li

“…The results showed that the detection frequencies of only triphenyl phosphate (TPHP), BDE-138 and BDE-197 (82.4 %, 61.2 % and 60.6 %, respectively) exceeded 60 % among the 34 compounds of interest, while the median concentrations of BDE-138 and BDE-197 were much higher than TPHP (medians of 103.6, 60.6 and 20.5 ng/g lw, respectively). …”
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The relationship between thiamin, folic acid and cognitive function in a rat model of uremia by Yifei Lu, Chenqi Xu, Kewei Xie, Bingru Zhao, Minzhou Wang, Cheng Qian, Xuemei Chen, Leyi Gu, Wangshu Wu, Renhua Lu

“…The Morris water maze was used to assess the cognitive function eight weeks post-surgery, and serum levels of thiamin, folic acid and homocysteine were detected subsequently. Brain and kidney tissues were collected for pathological examination and 8-Hydroxy-2’-deoxyguanosine (8-OHdG) immunochemistry staining. …”
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The impact of major congenital anomalies on obstetric outcomes in the United Arab Emirates: the Mutaba’ah Study by Hiba Adam, Nadirah Ghenimi, Anne F Minsart, Hassib Narchi, Shamsa Al Awar, Omniyat M Al Hajeri, Iffat Elbarazi, Rami H. Al-Rifai, Luai A. Ahmed

“…These findings underscore the need for early detection of MCAs in pregnancy, as this may help avoid obstetric complications. …”
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T cell receptors specific for an imatinib-induced mutation in BCR-ABL for adoptive T cell therapy by Meng-Tung Hsu, Gerald Willimsky, Gerald Willimsky, Gerald Willimsky, Leo Hansmann, Leo Hansmann, Leo Hansmann, Leo Hansmann, Thomas Blankenstein

“…By immunizing transgenic mice that express a diverse human T cell receptor (TCR) repertoire restricted to HLA-A2, we detected CD8+ T cell responses against the ABL-E255V, but not the ABL-T315I peptide. …”
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Rapid identification of high-temperature Daqu Baijiu with the same aroma type by UV-VIS sensor of HBT combined with Zn2+ by Yanmei Zhu, Yuanyuan Su, Yipeng Cang, Hengye Chen, Wanjun Long, Wei Lan, Xue Jiang, Haiyan Fu

“…Conclusions: This method not only improves the specificity of spectral detection, and the amount of information extracted from Baijiu samples, but also the detection time is shortened to less than 3 min, and the accurate identification of high-temperature Daqu Baijiu with the same aroma type was realized. …”
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JWST Imaging of Edge-on Protoplanetary Disks. IV. Mid-infrared Dust Scattering in the HH 30 Disk by Ryo Tazaki, François Ménard, Gaspard Duchêne, Marion Villenave, Álvaro Ribas, Karl R. Stapelfeldt, Marshall D. Perrin, Christophe Pinte, Schuyler G. Wolff, Deborah L. Padgett, Jie Ma, Laurine Martinien, Maxime Roumesy

“…Finally, we report the first detection of the proper motion of an emission knot associated with the mid-IR collimated jet detected by combining two epochs of our MIRI 12.8 μ m observations.…”
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The first two mitochondrial genomes from Apiotrichum reveal mitochondrial evolution and different taxonomic assignment of Trichosporonales by Qiang Li, Wenqi Xiao, Peng Wu, Ting Zhang, Peng Xiang, Qian Wu, Liang Zou, Mingying Gui

“…Frequent intron loss/gain events and potential intron transfer events have been detected in evolution of Agaricomycotina, Pucciniomycotina and Ustilaginomycotina. …”
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Urinary Proteome and Exosome Analysis Protocol for the Discovery of Respiratory Diseases Biomarkers by Laura Martelo-Vidal, Sara Vázquez-Mera, Pablo Miguéns-Suárez, Susana Belén Bravo-López, Heidi Makrinioti, Vicente Domínguez-Arca, Javier de-Miguel-Díez, Alberto Gómez-Carballa, Antonio Salas, Francisco Javier González-Barcala, Francisco Javier Salgado, Juan José Nieto-Fontarigo

“…Simultaneously, miRNA expression from urine exosomes was measured using either RTqPCR (pre-amplification) or nCounter Nanostring (non-amplication) analyses. We detected 548 different proteins in exosome-free urine samples (N = 5) with high confidence (FDR < 1%), many of them being expressed in different non-renal tissues. …”
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Radiomics analysis of thoracic vertebral bone marrow microenvironment changes before bone metastasis of breast cancer based on chest CT by Hao-Nan Zhu, Yi-Fan Guo, YingMin Lin, Zhi-Chao Sun, Xi Zhu, YuanZhe Li

“…Conclusion: CT-based radiomics can capture subtle changes in the thoracic vertebral bone marrow before breast cancer bone metastasis, offering a predictive tool for early detection of bone metastasis in breast cancer.…”
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Reactivation of Denervated Schwann Cells by Embryonic Spinal Cord Neurons to Promote Axon Regeneration and Remyelination by Xinyu Fang, Chaofan Zhang, Chongjing Zhang, Yuanqing Cai, Zibo Yu, Zida Huang, Wenbo Li, Wenming Zhang

“…The phenotypic changes and the neurotrophic factor expression pattern of SCs distal to the transplanted site were detected at several time points after cell transplantation and excision. …”
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Identifying malignant pleural effusion from tubercular pleural effusion by study of cancer ratio and cancer ratio plus by Subhankar Saren, Animesh Mandal, Amit Kumar Das, Ranjit Kumar Haldar, Sudipta Pandit

“…Background: Early detection of malignant pleural effusions (MPE) through routine biochemical tests will go a long way in improving morbidity and mortality of these patients. …”
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High Stability Single-Port Dual Band Microwave Sensor Based on Interdigital Capacitor Structure With Asymmetry Branch Feedline by Syah Alam, Indra Surjati, Lydia Sari, Raden Deiny Mardian, Teguh Firmansyah, Muhammad Iqbal, Slamet Widodo, Mudrik Alaydrus, Zahriladha Zakaria

“…This paper proposes a single-port interdigital capacitor (IDC) resonator based on asymmetric branch feed line with high stability performance for permittivity detection of solid materials with a permittivity range of 1 - 6.15. …”
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Histopathological Finding of Microdamage Accumulation in Atypical Subtrochanteric Femoral Fracture by Yo Watanabe, Naoki Kondo, Tomomi Fukuhara, Norio Imai, Masahiko Yamada, Naoto Endo

“…Callus formation was detected on a radiograph, and full weight-bearing was advised 12 weeks after the revision surgery. …”
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Tracking pygmy blue whale diving behaviour and validation of foraging areas defined from horizontal movement data by Michele Thums, Luciana C. Ferreira, Andrew Davenport, Micheline Jenner, Luciana Möller, Grace Russell, Robert D. McCauley, Curt Jenner

“…Despite a weak temporal relationship between putative (inferred from a movement model) and actual foraging, there was generally good spatial overlap detected, predominantly in high use areas, while more opportunistic foraging areas with lower use were less likely to be detected by the model. …”
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