Electroacupuncture Increases the Hippocampal Synaptic Transmission Efficiency and Long-Term Plasticity to Improve Vascular Cognitive Impairment by Yaling Dai, Yuhao Zhang, Minguang Yang, Huawei Lin, Yulu Liu, Wenshan Xu, Yanyi Ding, Jing Tao, Weilin Liu

“…The expression of synapse- and calcium-mediated signal transduction associated proteins was detected through western blotting. Results. The MWM behavioural results showed that EA significantly improved cognitive function in VCI model rats. …”
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Kidney damage on fertility and pregnancy: A Mendelian randomization. by Jin Ren, Qiuyan Huang, Xiaowei Lie, Xingli Tong, Qi Yao, Ge Zhou

“…Next, we introduced the Bayesian model averaging MR analysis to detect major causal relationships and render the results robust. …”
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Economic Evaluation of a Novel Lung Cancer Diagnostic in a Population of Patients with a Positive Low-Dose Computed Tomography Result by Michael J. Morris, Sheila A. Habib, Maggie L. Do Valle, John E. Schneider

“…**Background:** Early detection of lung cancer is crucial for improving patient outcomes. …”
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Deep learning in gonarthrosis classification: a comparative study of model architectures and single vs. multi-model methods by Sahika Betul Yayli, Kutay Kılıç, Salih Beyaz

“…The knee joint region was isolated using a YOLOv5 object detection model. The multi-model approach utilized three DL models: one for osteophyte detection, another for joint space narrowing analysis, and a third to combine these outputs with demographic and image data for KL classification. …”
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Clinical, biochemical and molecular characteristics of classic homocystinuria in Saudi Arabia and the impact of newborn screening on prevention of the complications: A tertiary cen... by Ahmed Sarar Mohamed, Talal AlAnzi, Amal Alhashem, Hadeel Alrukban, Fahad Al Harbi, Sarar Mohamed

“…Seven previously reported variants were detected in this cohort and one novel variant was found in three patients (c.828+2‐828+ 3 delins ACACTTGCATCC, p.?). …”
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A novel index for diagnosis of type 2 diabetes mellitus: Cholesterol, High density lipoprotein, and Glucose (CHG) index by Amin Mansoori, Mina Nosrati, Mohsen Dorchin, Fatemeh Mohammadyari, Elahe Derakhshan‐Nezhad, Gordon Ferns, Habibollah Esmaily, Majid Ghayour‐Mobarhan

“…Conclusions The CHG index could be useful for the detection of type 2 diabetes mellitus.…”
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Prediction of Genes Related to Positive Selection Using Whole-Genome Resequencing in Three Commercial Pig Breeds by HyoYoung Kim, Kelsey Caetano-Anolles, Minseok Seo, Young-jun Kwon, Seoae Cho, Kangseok Seo, Heebal Kim

“…In this study, cross-population extended haplotype homozygosity and cross-population composite likelihood ratio tests were implemented to detect genes experiencing positive selection for the genome-wide resequencing data generated from three commercial pig breeds. …”
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Ameliorative Effects of Polygonatum kingianum Polysaccharides on Lipid Metabolism Disorders and Brain Function Impairments in Obese Mice by XU Yuncong, YAN Qiaojuan, ZHU Chunhua, YANG Shaoqing, LI Houjiang, JIANG Zhengqiang

“…Behavioral changes were detected to assess the autonomic activity and anxiety-like behavior of mice, and inflammation levels in liver, adipose tissue, serum, and brain as well as pathomorphological changes in brain were detected. …”
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Natural exposure to Chikungunya virus in golden-headed lion tamarin (Leontopithecus chrysomelas, Kuhl, 1820) from non-protected areas in southern Bahia, Brazil: Implications and si... by Sofía Bernal-Valle, María Angélica Monteiro de Mello Mares-Guia, Filipe Vieira Santos de Abreu, Fabrício Souza Campos, Cirilo Henrique de Oliveira, Antônio Victor Veloso Ramos, Reizane Pereira Lordelo, Kristel De Vleeschouwer, Leonardo de Carvalho Oliveira, Hllytchaikra Ferraz Fehlberg, Ana Maria Bispo Filippis, Bergmann Morais Ribeiro, Paulo Michel Roehe, Anaiá da Paixão Sevá, Danilo Simonini-Teixeira, George Rego Albuquerque

“…CHIKV viremia was not detected in any specimens (as assayed by RT-qPCR). …”
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Molecular Epidemiology of Human Norovirus Variants from Outbreaks in Zhejiang Province, China, during 2021 by Yi Sun, Yongjuan Yuan, Haiyan Mao, Lingxuan Su, Qiong Ge, Jian Gao, Changping Xu, Liming Gong

“…The presence of norovirus genogroups I (GI) and II (GII), along with sapovirus, was detected. Subsequently, the specimens positive for norovirus were sequenced for genotyping purposes. …”
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sORFdb – a database for sORFs, small proteins, and small protein families in bacteria by Julian M. Hahnfeld, Oliver Schwengers, Lukas Jelonek, Sonja Diedrich, Franz Cemič, Alexander Goesmann

“…In recent years, the development of ribosome profiling protocols has led to the detection of an increasing number of previously unknown small proteins. …”
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Determination of Natural Capsaicin, Dihydrocapsaicin and Synthetic Capsaicin in Hot Pepper and Its Products by QuEChERS Combined with HPLC by CHENG Luyao, WEN Yajun, SHI Wenting, ZHOU Ziying, MA Liyan

“…The limits of detection (LOD) and quantification (LOQ) of natural capsaicin were 0.014–0.069 mg/kg and 0.046–0.23 mg/kg, respectively. …”
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SIRT1/PGC-1α-mediated mitophagy participates the improvement roles of BMAL1 in podocytes injury in diabetic nephropathy: evidences from in vitro experiments by Yanxia Rui, Yinfeng Guo, Linying He, Min-er Wang, Henglan Wu

“…Mitophagy was examined by detecting autophagosomes using transmission electron microscopy, and detecting the colocalization of LC3 and Tom20 using immunofluorescence staining. …”
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Identification of the etiological agent of equine piroplasmosis in Western and Eastern Siberia by V. A. Rar, V. A. Marchenko, E. A. Efremova, O. V. Suntsova, O. V. Lisak, A. Y. Tikunov, I. V. Meltsov, N. V. Tikunova

“…Surprisingly, DNA of B. caballi was not found in any of the samples examined, even though this agent had previously been detected in many regions in Russia, including Altai. …”
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RETRACTED ARTICLE: Combined treatment of glibenclamide and CoCl2 decreases MMP9 expression and inhibits growth in highly metastatic breast cancer by Zhe Rong, Li Li, Fei Fei, Lailong Luo, Yang Qu

“…Some fresh tissues without necrosis were stored at −80°C for mRNA detection and the other tumor tissue was fixed with 10% formalin for H&E and immunohistochemical staining. …”
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Symptom descriptors and patterns in lumbar radicular pain caused by disc herniation: a 1-year longitudinal cohort study by Lars Grøvle, Anne Julsrud Haugen, Eivind Hasvik

“…Objective The objective of the present study was to explore the diversity, quality, severity and distribution of symptoms in patients with radicular pain and a lumbar disc herniation.Design Longitudinal cohort study.Setting Hospital-based back clinic.Participants Ninety patients referred to secondary healthcare with (a) low back-related leg pain, (b) age between 18 and 65 years and (c) MRI confirmed lumbar disc herniation at a relevant side and level.Outcome measures Neuropathic pain symptoms were assessed using the Short-Form McGill Pain Questionnaire-2 (SF-MPQ-2) and the painDETECT Questionnaire. In a subsample classified with neuropathic pain, in-depth interviews were performed, and symptomatic areas were drawn on standardised body charts.Results At baseline, the most frequently used painDETECT symptom descriptor was numbness sensation, reported by 94%, followed by sudden pain attacks and tingling or prickling. …”
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Evaluating Methods for Aflatoxin B1 Monitoring in Selected Food Crops Within Decentralized Agricultural Systems by Haadia Tanveer, Hannah Glesener, Blake Su, Brooke Bolsinger, Rosa Krajmalnik-Brown, Lee E. Voth-Gaeddert

“…The objectives of this study were: (1) to evaluate common AFB1 detection methods, including enzyme-linked immunosorbent assays (ELISA) and lateral-flow assays (LFA), validated via high-performance liquid chromatography (HPLC), focusing on their suitability for possible applications in decentralized, low-resource settings; and (2) to conduct a barriers-to-use assessment for commonly available AFB1 detection methods and their applicability in low-resource settings. …”
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Association of HLA-B27 Gene and Rheumatoid Arthritis: Analysis of Potential Role as a Predictive Biomarker by Karzan Ghafur Khidhir, Baban Ahmad, Dana Khdr Sabir

“…This study investigated the relative expression of HLA-B27 gene in RA patients compared to normal control and assesses its suitability as a biomarker for early detection of RA. Bioinformatics analysis was used to determine the profile of HLA-B27 gene in different human tumors to demonstrate the possible involvement of HLA-B27 in both RA and cancer; and also, to discover its functional association with other human genes. …”
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Assessing the diagnostic accuracy of radiological and histological findings in the diagnosis of non-alcoholic fatty liver disease stages among patients in a tertiary hospital by Ekpe Edemekong L, Emanghe U, Ekpe EL, Obiora IC, Yemiode Itam, Akinmola OO

“…Background: Early screening, detection, and early intervention are life-saving modalities to lessen the impact and burden of non-communicable diseases. …”
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The Synergistic Effects of Celastrol in combination with Tamoxifen on Apoptosis and Autophagy in MCF-7 Cells by Lijun Wang, Luqun Tang, Chengyun Yao, Chunyan Liu, Yongqian Shu

“…Moreover, the distribution of LC3 was monitored by immunofluorescence, and the changes in the LC3II and P62 levels detected by western blot analysis suggested that celastrol in combination with tamoxifen triggered autophagy. …”
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