Development of a Prediction Model and Risk Score for Self-Assessment and High-Risk Population Identification in Liver Cancer Screening: Prospective Cohort Study by Xue Li, Youqing Wang, Huizhang Li, Le Wang, Juan Zhu, Chen Yang, Lingbin Du

“…ObjectiveThis study aimed to develop a simple prediction model and risk score for liver cancer screening in the general population, with the goal of improving early detection and survival. MethodsThis population-based cohort study focused on residents aged 40 to 74 years. …”
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Effectiveness of Noninvasive Positive Pressure Ventilation Combined with Enteral Nutrition in the Treatment of Patients with Combined Respiratory Failure after Lung Cancer Surgery... by Yongjun Zhang, Lanbo Liu, Dawei Li, Dongsheng Zhou

“…The curative effects of two groups after treatment were compared, and the pulmonary function indexes (maximum expiratory pressure (PEmax), maximum midexpiratory flow rate (MMF), and maximum ventilation volume (MVV)), blood gas indexes (blood oxygen partial pressure (PaO2) and partial pressure of carbon dioxide (PaCO2)), oxygen metabolism indicators [mixed venous oxygen tension (PvO2) and central venous oxygen saturation (ScvO2)], nutritional status indicators (hemoglobin (HGB), serum albumin (ALB), and total protein (TP)), and nutritional score before and after treatment in two groups were detected, and the 6-month follow-up of the two groups was recorded. …”
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Addressing inhaler technique challenges in cognitively impaired chronic obstructive pulmonary disease patients: the impact of customized training programs by Vaishnavi V Gaonkar, Vinay V Shanbhag, Shreya S Kajave, Mahek R Mattikop, Mandati Santhosh Reddy

“…Patients exhibiting improper inhaler-using skills were detected, corrected, and trained. Inhaler techniques were reassessed immediately and at follow-up visits. …”
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Prevalence of carbapenemase-encoding genes carriage in patients admitted to multidisciplinary hospital in Moscow by Ni O.G., Shifman E.M., Yakovlev S.V., Bykov A.O., Gorbacheva A.A., Kruglov A.N., Belotserkovskiy B.Z., Matyushkov N.S., Galata A.A., Protsenko D.N.

“…Genes blaKPC and blaOXA-51 were detected with the same frequency (14.7%). The other genes were less common, from 0.6% (blaIMP) to 10.3% (blaOXA-51). …”
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Sensitivity to the Demethylation Inhibitor Difenoconazole Among Baseline Populations of Various <i>Penicillium</i> spp. Causing Blue Mold of Apples and Pears by Madan Pandey, Clayton L. Haskell, Juliette D. Cowell, Achour Amiri

“…Notable polymorphism was detected in the <i>CYP51</i> gene of the “non-<i>expansum</i>” species with four mutations located at four residues. …”
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Are we serologically prepared against an avian influenza pandemic and could seasonal flu vaccines help us? by Iván Sanz-Muñoz, Javier Sánchez-Martínez, Carla Rodríguez-Crespo, Corina S. Concha-Santos, Marta Hernández, Silvia Rojo-Rello, Marta Domínguez-Gil, Ahmed Mostafa, Luis Martinez-Sobrido, Jose M. Eiros, Aitor Nogales

“…Importantly, HPAI H5N1 viruses with genetic markers of adaptation to mammals have been detected. Together with HPAI H5N1, avian influenza viruses H7N9 (high and low pathogenic) stand out due to their high mortality rates in humans. …”
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Synthesizing field plot and airborne remote sensing data to enhance national forest inventory mapping in the boreal forest of Interior Alaska by Pratima Khatri-Chhetri, Hans-Erik Andersen, Bruce Cook, Sean M. Hendryx, Liz van Wagtendonk, Van R. Kane

“…These rapid ecological shifts necessitate fine-scale monitoring of forest type to detect potential type conversions and guide management interventions. …”
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Research Status and Direction of Chronic Obstructive Pulmonary Disease Complicated with Coronary Heart Disease: A Bibliometric Analysis from 2005 to 2024 by Bian H, Zhu S, Xing W, Qi L, Xue J, Peng X, Jin Z, Zhao H

“…To improve the early detection rate of COPD complicated with CHD, the main development direction in the future is to extract computed tomography (CT) features using imaging omics and establish an early prediction model. …”
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Potential drug targets for asthma identified through mendelian randomization analysis by Xingxuan Chen, Yu Shang, Danting Shen, Si Shi, Zhe Wen, Lijuan Li, Hong Chen

“…Bidirectional Mendelian randomization analysis, Steiger filtering, colocalization, and phenotype scanning were employed for reverse causal inference detection, further substantiating the Mendelian randomization results. …”
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Pemeriksaan Laboratorium Cystatin C Untuk Uji Fungsi Ginjal by Rismawati Yaswir, Afrida Maiyesi

“…Mild decrease in renal function detected by CysC faster than creatinine. To assess the reduction in LFG, the sensitivity, specificity, and diagnostic efficiency of the most well CysC (98%) obtained when used above the cut off limit CysC levels of 1.31 mg/l. …”
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Mapping and Analysis of Exit Strategy Research: A Bibliometrics and Systematic Review by Alireza Valipour, Ali Heidari, Mohammad Ali Shahhosseini, Asadollah Kordnaiej

“…Based on these findings, future research avenues include investigating the role of diversification as a driver of business exits, exploring how corporate governance structures influence both firm performance and exit decisions, analyzing factors contributing to non-optimal timing of business exits, examining the potential for reusing resources in new ventures to facilitate exits and minimize negative consequences, investigating the role of organizational capabilities in early detection of exit signals, and conducting a comprehensive exploration of both internal and external consequences of business exits, along with effective response strategies.…”
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Dietary supplementation with compound microecological preparations: effects on the production performance and gut microbiota of lactating female rabbits and their litters by Chengcheng Zhao, Youhao Li, Hui Wang, Ahamba Ifeanyi Solomon, Shuhui Wang, Xianggui Dong, Bing Song, Zhanjun Ren

“…Moreover, the limited sample size in this study may hinder the detection of subtle effects, and augmenting the sample size will bolster the reliability of the study findings.IMPORTANCEThe intestinal environment of rabbits is fragile and susceptible to environmental influences, leading to inflammatory intestinal diseases. …”
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Characterization of dynamic stall of a wind turbine airfoil with a high Reynolds number by H. R. Kim, J. A. Printezis, J. D. Ahrens, J. R. Seume, L. Wein

“…The MCSP exhibits a breakdown in magnitude at the onset of the dynamic-stall formation stage and full stall, while the TESP supports indicating the emergence of a full stall by detecting the trailing-edge vortex.</p>…”
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Cost&ndash;Benefit Analysis of in vivo Reflectance Confocal Microscopy for Melanoma Diagnosis in a Real-World Clinical Setting by Bruno GM, Di Matteo S, Longo C, Stanganelli I, Farnetani F, Borsari S, Mazzoni L, Ciardo S, Raucci M, Magi S, Bassoli S, Spadafora M, Mandel VD, Casari A, Chester J, Kaleci S, Colombo GL, Pellacani G

“…., Health Economics & Outcomes Research, Milan, Italy; 3Azienda Unità Sanitaria Locale – IRCCS di Reggio Emilia, Skin Cancer Center, Reggio Emilia, Italy; 4Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy; 5Skin Cancer Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola, Italy; 6Department of Medicine and Surgery, University of Parma, Parma, Italy; 7Dermatology Unit, Department of Surgical, Medical, Dental & Morphological Sciences with Interest Transplant, Oncological & Regenerative Medicine, University of Modena and Reggio Emilia, Modena, 41125, Italy; 8Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy; 9Porphyria and Rare Diseases Unit, San Gallicano Dermatological Institute-IRCCS, Roma, Italy; 10Department of Drug Sciences, CEFAT-Center of Pharmaceuticals Economics and Medical Technologies Evaluation, University of Pavia, Pavia, Italy; 11Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Dermatology Clinic, Sapienza University of Rome, Rome, Italy&ast;These authors contributed equally to this workCorrespondence: Giacomo Matteo Bruno, Department of Drug Sciences, University of Pavia, Pavia, Italy, Email giacomomatteo.bruno@unipv.itBackground: In a recent prospective, multicenter, two-arm randomized controlled trial (RCT), we demonstrated that adjunctive reflectance confocal microscopy (RCM) in routine clinical practice provides clinical benefits, including safe melanoma detection and a 43.3% reduction in the number needed to excise (NNE).Methods: A cost–benefit analysis was conducted based on NNEs for standard care (5.3) and adjunctive RCM (3.0). …”
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Resveratrol contributes to NK cell-mediated breast cancer cytotoxicity by upregulating ULBP2 through miR-17-5p downmodulation and activation of MINK1/JNK/c-Jun signaling by Bisha Ding, Jie Li, Jia-Lin Yan, Chun-Yan Jiang, Ling-Bo Qian, Jie Pan

“…This study aims to investigate how RES affects the expression of ULBP2 and the sensitivity of breast cancer (BC) cells to NK cell cytotoxicity, along with the underlying mechanisms.MethodsThe effects of RES on ULBP2 expression were detected with qRT-PCR, western blot, flow cytometry analysis and immunohistochemistry. …”
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Spatial characteristics and health risks assessments of trace metal pollution from road dusts in the industrialized city of Bangladesh by Masum Howlader, Ashik Md Mamun, Mohammad Mahfuzur Rahman, Md Hasibur Rahman, Sadhon Chandra Swarnokar, Mahfuza Sultana, Md Tanvir Rahman, Tusar Kumar Das

“…These samples underwent analysis using ICP-MS to detect potential toxic trace metals. Subsequently, the level of pollution and the associated human health risks were evaluated. …”
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Determination of a normal orogenic palaeo-geothermal gradient with clay mineral and organic matter indices: a review by Rafael Ferreiro Mählmann, Meinert Rahn, Sébastien Potel, Lan Nguyen-Thanh, Rainer Petschick

“…The study illustrates that a normal geotherm can be described by VR/KI correlation, even if different heating episodes may occur. For the detection of a poly-phase or plurifacial thermal history, several indices of clay minerals and organic matter with very different kinetics should be used, as e.g. demonstrated by strong differences in smectite content at equal VR/KI values versus structural depth. …”
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The clinical prediction model to distinguish between colonization and infection by Klebsiella pneumoniae by Xiaoyu Zhang, Xifan Zhang, Deng Zhang, Jing Xu, Jingping Zhang, Xin Zhang

“…ObjectiveTo develop a machine learning-based prediction model to assist clinicians in accurately determining whether the detection of Klebsiella pneumoniae (KP) in sputum samples indicates an infection, facilitating timely diagnosis and treatment.Research methodsA retrospective analysis was conducted on 8,318 patients with KP cultures admitted to a tertiary hospital in Northeast China from January 2019 to December 2023. …”
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Volatile components, total phenolic compounds, and antioxidant capacities of worm-infected Gomphidius rutilus by Libin Sun, Wei He, Guang Xin, Pengju Cai, Yin Zhang, Zhiyong Zhang, Yunyun Wei, Bingxin Sun, Xiaowen Wen

“…A total of 17 and 19 types of volatile compounds were detected, including ketones, alcohols, benzene, alkenes, aldehydes, esters, acids, and alkanes. …”
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Randomized, observer-blind, controlled Phase 1 study of the safety and immunogenicity of the Na-GST-1/Alhydrogel hookworm vaccine with or without a CpG ODN adjuvant in hookworm-naï... by David J Diemert, Maria Zumer, Mark Bova, Christina Gibbs-Tewary, Elissa M Malkin, Doreen Campbell, Lara Hoeweler, Guangzhao Li, Maria Elena Bottazzi, Peter J Hotez, Jeffrey M Bethony

“…IgG levels decreased but remained significantly above baseline in all groups by day 290, at which point all participants (20 of 20 evaluable participants) still had detectable IgG. Longitudinal antigen-specific IgG1 and IgG3 subclass responses mirrored those of total IgG, whereas IgG4 responses were lower in the groups that received the vaccine with the CpG adjuvant compared to the non-CpG group.…”
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