Reduction of Lipid-Core Burden Index in Nonculprit Lesions at Follow-Up after ST-Elevation Myocardial Infarction: A Randomized Study of Bioresorbable Vascular Scaffold versus Optim... by Joelle Kefer, Patrick Chenu, Olivier Gurné, Frederic Maes, Théophile Tamakloé, Christophe Beauloye

“…Near-infrared spectroscopy (NIRS) detects LRPs using the maximum 4 mm lipid-core burden index (maxLCBI4 mm). …”
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Electrical and Viscoelastic Parameters of Erythrocytes as a Part of Diagnostic Models for Differentiating Fatty Liver Disease of Mixed Genesis from Non-Alcoholic and Alcohol-Relate... by M. V. Kruchinina, M. F. Osipenko, M. V. Parulikova, A. A. Gromov

“…The electrical and viscoelastic parameters of erythrocytes were investigated by the diagnostic technique of dielectrophoresis using an electrooptical cell detection system.Results. The most significant parameters for differentiating fatty liver disease of mixed genesis (metabolic + alcoholic) from NAFLD using the Volcano plot have turned out to be cell polarizability at a frequency of 106 Hz (p = 6.49 ×10-5), erythrocyte cell membrane capacity (p = 0.00077), relative polarizability (p = 0.001), the levels of which were higher in patients with NAFLD. …”
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Remimazolam Suppresses Oxidative Stress and Apoptosis in Cerebral Ischemia/Reperfusion Injury by Regulating AKT/GSK-3β/NRF2 Pathway by Duan M, Yu N, Liu J, Zhao Y, Zhang J, Song S, Wang S

“…The viability and apoptosis rate of SY5Y cells, neurological deficit score, cerebral infarction volume and morphological changes of rat brain cells as well as the protein expression of Bax, Bcl2, Caspase 3, Cleaved-Caspase 3 and the number of TdT-mediated dUTP Nick-End Labeling (TUNEL)-positive cells in the penumbral region were detected. Reactive oxygen species (ROS), malondialdehyde (MDA), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), NRF2, heme oxygenase 1 (HO-1), AKT, P-AKT, GSK-3β, P-GSK-3β protein expression, and nuclear translocation of NRF2 were measured in cell and animal assays.Results: Reduced SY5Y cell viability and increased apoptosis caused by OGD/R injury, elevated neurological deficit scores and cerebral infarct volume induced by brain I/R injury in rats, cerebral cell injury, as well as elevated Bax, Cleaved-Caspase 3, decreased Bcl2, and increased number of TUNEL-positive cells in rat brain tissue were all moderated by remimazolam. …”
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Effect of cisplatin/gold chitosan nanocomposite on oral squamous cell carcinoma and oral epithelial cells by Basma Abdelrahman Ahmed, Rania Osama M. Mohsen, Marwa Sharaky, Marwa A. Ramadan, Amna H. Faid, Mai Hafez Mohamed

“…Conversely, opposite results were detected in AuCh Nps and Cis/AuCh nanocomposite-treated OEC. …”
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Cardiac manifestations of Fabry disease in G3Stg/GlaKO and GlaKO mouse models-Translation to Fabry disease patients. by Abirami Kugadas, Pietro Artoni, Wanida Ruangsiriluk, Meng Zhao, Natalia Boukharov, Rizwana Islam, Dmitri Volfson, Katayoun Derakhchan

“…Significant reduction in Global longitudinal strain (GLS) measuring local myofiber contractility of the LV was also detected at 13-months. Similar GLS reduction was also reported in FD patients. …”
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Kangtaizhi Granule Alleviated Nonalcoholic Fatty Liver Disease in High-Fat Diet-Fed Rats and HepG2 Cells via AMPK/mTOR Signaling Pathway by Jiaxin Zhang, Haixia Du, Menglan Shen, Zhengqi Zhao, Xinmiao Ye

“…MTT assay, intracellular TG level, oil red O staining, and glucose uptake in cells were detected. Western blotting and immunohistochemical and immunofluorescence staining were also performed to determine the expression of lipid-related genes PPAR-γ, SREBP-1, p-AKT, FAS, and SIRT1 and genes in the AMPK/mTOR signaling pathway. …”
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Effect of temporal water restrictions on drinking behavior and time budget in lactating dairy cows according to their position in the social hierarchy within the herd by E. Nizzi, O. Dhumez, C. Hurtaud, A. Boudon

“…Cow social dominance hierarchies were characterized using normalized David's scores, which were calculated from video-detected replacements at each pen's drinker. During the last 4 d of each treatment period, drinking behavior was measured using interconnected drinkers, and eating, idle, and lying times were measured using accelerometers. …”
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Clinical Features of COVID‐19 Associated Pulmonary Aspergillosis: A Multicenter, Retrospective Study by Yasheng Zhan, Guojun He, Cheng Zhong, Yake Yao, Jiangying Zhou, Tong Li, Hua Zhou

“…Patients with CAPA had no specific clinical symptoms and lung imaging manifestations, and diagnosis depended on Aspergillus culture and galactomannan detection. For patients with COVID‐19 with these high‐risk factors, Aspergillus culture and GM testing should be performed actively to avoid delaying the diagnosis of CAPA.…”
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Antibacterial Potential of Honeybee Venom and <i>Monascus purpureus</i> Extracellular Metabolites Against Multidrug-Resistant Pathogenic Bacteria by Islam I. Teiba, Yasser S. A. Mazrou, Abeer H. Makhlouf, Yasser Nehela, Abdallah E. Mohamed, Ahmed M. Abbas, Islam Mamdouh, Emad H. El-Bilawy

“…Further multi-ligand docking-based virtual screening studies are required to identify the most promising detected metabolite(s) within both BV and RD extracts.…”
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High BMP7 Expression May Worsen Airway Disease in COPD by Altering Epithelial Cell Behavior by Dong W, Xie M, Ming C, Li H, Xu X, Cui L, Wang W, Li Y

“…BMP7 expression in the airway epithelium and the BMP7 level in sputum supernatants were detected. Human primary bronchial epithelial cells (HPBECs) were isolated by bronchoscopy from healthy individuals. …”
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Solitary vitreous cysts: a series of case reports by A.B. Galimova, I.V. Baranchikova, G.I. Garipova, I.R. Karachurina, R.Yu. Ziyazetdinova

“…All patients underwent a standard ocular examination and enzyme immunoassay to detect antibodies against Toxoplasma, Taenia solium, and Echinococcus. …”
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Technologies for Interoperable Internet of Medical Things Platforms to Manage Medical Emergencies in Home and Prehospital Care: Scoping Review by Mattias Seth, Hoor Jalo, Åsa Högstedt, Otto Medin, Bengt Arne Sjöqvist, Stefan Candefjord

“…ConclusionsIoMT platforms that support higher levels of interoperability have the potential to deliver personalized patient care, enhance overall patient experience, enable early disease detection, and minimize time delays. However, our findings highlight a prevailing emphasis on lower levels of interoperability within the IoMT research community. …”
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Exploration of Degradation Mechanism of Chlorogenic Acids in Stevia Based on UPLC-QTOF MS/MS by Juan-juan WU, Zi-xuan WANG, Yun-he LIAN, Li-juan HOU, Zhi-ping NIU, Wen-chang WANG, Di WU

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Comprehensive overview of genotype distribution and prevalence of human papillomavirus in cervical lesions by Yang Liu, Chengquan Zhao, Tiannan Wang, Yuhong Ye, Terrel Jones, Xianxu Zeng

“…This review aims to provide a comprehensive summary detailing the distribution and profile of HPV genotypes detected in cervical lesions, leveraging insights from histological and cytological findings. …”
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Association between sex steroid hormones and α-klotho: Results from the NHANES 2013-2016 and Mendelian randomization study by Andong Guo, Pengcheng Chen, Jishuang Cao, Chenrui Wu, Sentai Ding

“…Results: In men, significant positive correlations with α-Klotho were consistent across both unadjusted and fully adjusted models for total testosterone (TT), bio-available testosterone (Bio-T), estradiol (E2) and sex hormone-binding globulin (SHBG) (Model 3: TT: β = 3.54, 95 % CI: 1.63–5.44, P = 0.0003; Bio-T: β = 1.74, 95 % CI: 0.73–2.74, P = 0.0007; E2: β = 0.25, 95 % CI: 0.11–0.38, P = 0.0003; SHBG: β = 0.95, 95 % CI: 0.63–1.27, P < 0.0001); In premenopausal women, we detected a potential nonlinear relationship between TT levels and α-Klotho, with α-Klotho levels rising to a peak at a TT level of 72.2 ng/mL, after which they declined. …”
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Exploring dental students' knowledge on oral cancer prevention: a cross-sectional study in Moldova, Armenia, and Belarus by Olga Golburean, Diana Uncuta, Gayane Manrikyan, Natalia Shakavets, Izabella Vardanyan, Marina Markaryan, Ferda Özkaya, Daniela-Elena Costea, Tarig Al-Hadi Osman

“…Dentists play a vital role in early detection of OC through oral mucosal examination, and in informing the patients about avoidable risk factors of the disease, such as tobacco and excessive alcohol use. …”
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The Diagnostic Value of Plasma NETs Levels and iCEB in Silent Myocardial Ischemia in Maintenance Hemodialysis Patients by Liu H, Han J, Ni W, Lu Y, Hu X, Wang J, Zhou Y, Wang Z, Cao J, Liu H

“…The ROC analysis demonstrated the potential diagnostic accuracies of NETs levels and iCEB, with an area under the curve (AUC) of 0.908, sensitivity of 0.987, and specificity of 0.829 for identifying SMI.Conclusion: The study highlights the combined diagnostic value of plasma NETs levels and iCEB in identifying SMI in MHD patients, providing valuable insights into potential early detection and risk stratification strategies for this population.Keywords: silent myocardial ischemia, hemodialysis, neutrophil extracellular traps, index of cardiac electrophysiological balance, diagnostic value, cardiovascular complications…”
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Sistem Identifikasi Penyakit Paru Obstruktif Kronik (PPOK) Berdasarkan Suara Paru-Paru Menggunakan Jaringan Saraf Tiruan Berbasis Raspberry Pi by Lindhu Parang Kusuma, Barlian Henryranu Prasetio, Eko Setiawan

“…This system works by detecting whether the sound of the lungs is COPD infected or healthy. …”
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Serum IL-1<mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math>, IL-2, and IL-6 in Insulin-Dependent Diabetic Children

“…In all stages of diabetes higher levels of IL-1<mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math> and TNF-<mml:math alttext="$alpha $"> <mml:mi>&#x03B1;</mml:mi> </mml:math> and lower levels of IL-2 and IL-6 were detected. Our data about elevated serum IL-1<mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math>, TNF-<mml:math alttext="$alpha $"> <mml:mi>&#x03B1;</mml:mi> </mml:math> and decreased IL-2, IL-6 levels in newly diagnosed IDDM patients in comparison with longer standing cases supports an activation of systemic inflammatory process during early phases of IDDM which may be indicative of an ongoing <mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math>-cell destruction. …”
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Inflammatory changes in the choroid plexus following subarachnoid hemorrhage: the role of innate immune receptors and inflammatory molecules by Peter Solár, Peter Solár, Václav Brázda, Václav Brázda, Martin Bareš, Alemeh Zamani, Parisa EmamiAref, Andrea Joukal, Lucie Kubíčková, Erik Kročka, Klaudia Hašanová, Marek Joukal

“…The level of TLR4, TLR9, FPR2, CCL2, TNFα, IL-1β was detected by measuring immunofluorescence intensity in randomly selected epithelial cells. …”
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