Electrochemotherapy with bleomycin, oxaliplatin, or cisplatin in mouse tumor models, from tumor ablation to in situ vaccination by Katja Uršič Valentinuzzi, Katja Uršič Valentinuzzi, Urška Kamenšek, Urška Kamenšek, Simona Kranjc Brezar, Chloe Heranney, Chloe Heranney, Tilen Komel, Tilen Komel, Simon Buček, Simon Buček, Maja Čemažar, Maja Čemažar, Gregor Serša, Gregor Serša

“…Variances in the antitumor (immune) response were also detected based on the chemotherapeutic drug used in ECT. …”
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A Retrospective Study on Amoxicillin Susceptibility in Severe Haemophilus influenzae Pneumonia by Pierre Danneels, Maria Concetta Postorino, Alessio Strazzulla, Nabil Belfeki, Aurelia Pitch, Frank Pourcine, Sebastien Jochmans, Vincent Dubée, Mehran Monchi, Sylvain Diamantis

“…Amoxicillin resistance was stable over time, but no risk factors were detected. AMC resistance was extremely low, suggesting that AMC could be used for empiric treatment of Hi pneumonia, as well as other molecules, namely, cephalosporins. …”
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Effects of Simulated Circulation Temperature Changes on the Flavor of Lentinula edodes during Storage by LIU Yani, WANG Feiyu, LI Ran, GAO Hong, FAN Xiuzhi, YIN Chaomin, CHENG Shilun, YU Wei, SHI Defang

“…In total, 55 volatile compounds were detected by GC-IMS, including 16 alcohols, 10 aldehydes, 8 terpenes, 6 ketones, 4 esters, and 11 other compounds. …”
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Clinicopathological Significance of FOXO4 Expression and Correlation with Prx1 in Head and Neck Squamous Cell Carcinoma by Yunping Lu, Yajun Shen, Lingyu Li, Min Zhang, Min Wang, Lihua Ge, Jing Yang, Xiaofei Tang

“…The expression of FOXO4 was detected in Prx1 silenced CaL27 and SCC9 cell lines by Western blot. …”
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Effects of celastrol on the heart and liver galaninergic system expression in a mouse model of Western-type diet-induced obesity and metabolic dysfunction-associated steatotic live... by Nikolina Canová, Jana Šípková, Mahak Arora, Zuzana Pavlíková, Zuzana Pavlíková, Tomáš Kučera, Ondřej Šeda, Tijana Šopin, Tomáš Vacík, Ondřej Slanař

“…Fatostatin suppressed gene expression of all the detected members of the galaninergic system in the heart ventricles, depicting the role of SREBP in this process.ConclusionThese findings suggest that celastrol may beneficially modulate the galaninergic system under obesity and MASLD-to-MASH progression, indicating its potential as a therapeutic agent for disorders associated with metabolic dysfunction.…”
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Explainable artificial intelligence in web phishing classification on secure IoT with cloud-based cyber-physical systems by Sultan Refa Alotaibi, Hend Khalid Alkahtani, Mohammed Aljebreen, Asma Alshuhail, Muhammad Kashif Saeed, Shouki A. Ebad, Wafa Sulaiman Almukadi, Moneerah Alotaibi

“…The XAIAOA-WPC method utilizes a multi-head attention-based long short-term memory (MHA-LSTM) model for web phishing recognition. Besides, the detection outcomes of the MHA-LSTM approach are enhanced by using the Aquila optimization algorithm (AOA) model. …”
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Seroprevalence of dengue, Zika, and chikungunya in São Sebastião, Brazil (2020–2021): a population-based survey by Tayane Nobre, Andre Luiz Dutra Fenner, Emerson Luiz Lima Araújo, Wildo Navegantes de Araújo, Emmanuel Roux, Pascal Handschumacher, Helen Gurgel, Bruno Dallago, Mariana Hecht, Luciana Hagström, Walter Massa Ramalho, Nadjar Nitz

“…ELISA serological tests were performed to detect IgM and IgG antibodies against dengue, Zika virus, and chikungunya. …”
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Escherichia coli combination with PD-1 blockade synergistically enhances immunotherapy in glioblastoma multiforme by regulating the immune cells by Guochen Li, Haiyan Yang, Tengfei Ke, Na Tan, Xiaolan Du, Xirui Duan, Xinyan Zhou, Guangrong Zheng, Chengde Liao

“…ELISA kits were used to detect innate immune cytokines. Flow cytometry and immunofluorescence staining were used to investigate T cells. …”
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Fibroblast growth factor 21 predicts arteriovenous fistula functional patency loss and mortality in patients undergoing maintenance hemodialysis by Xinhui Hu, Hong Ding, Qing Wei, Ruoxin Chen, Weiting Zhao, Liqiong Jiang, Jing Wang, Haifei Liu, Jingyuan Cao, Hong Liu, Bin Wang

“…FGF21 concentration was detected using enzyme-linked immunosorbent assay. Patients were followed up to record two clinical outcomes, AVF functional patency loss and all-cause mortality. …”
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Prognosis of nodal micrometastasis in resectable pN0 non-small cell lung cancer by Sophon Siwachat, Sophon Siwachat, Sophon Siwachat, Apichat Tantraworasin, Apichat Tantraworasin, Apichat Tantraworasin, Nirush Lertprasertsuke, Somcharoen Saeteng, Somcharoen Saeteng

“…However, the benefits of NMM detection in resectable cases remain controversial due to conflicting results from retrospective studies. …”
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Contagious acquisition of antimicrobial resistance is critical for explaining emergence in western Canadian feedlots—insights from an agent-based modelling tool by Dana Ramsay, Wade McDonald, Michelle Thompson, Nathan Erickson, Sheryl Gow, Nathaniel D. Osgood, Cheryl Waldner

“…Hypotheses about how AMR emerges in the feedlot environment were represented by model configurations in which detectable AMR was impacted by (1) only selection arising from AMU; (2) only transmission between animals in the same pen; and (3) both AMU-linked selection and transmission. …”
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Clinical Characteristics of Virologically Confirmed Respiratory Syncytial Virus in English Primary Care: Protocol for an Observational Study of Acute Respiratory Infection by Uy Hoang, Utkarsh Agrawal, José Manuel Ordóñez-Mena, Zachary Marcum, Jennifer Radin, Andre Araujo, Catherine A Panozzo, Orsolya Balogh, Mihir Desai, Ahreej Eltayeb, Tianyi Lu, Catia Nicodemo, Xinchun Gu, Rosalind Goudie, Xuejuan Fan, Elizabeth Button, Jessica Smylie, Mark Joy, Gavin Jamie, William Elson, Rachel Byford, Joan Madia, Sneha Anand, Filipa Ferreira, Stavros Petrou, David Martin, Simon de Lusignan

“…In the 2023-2024 winter RSV detection in the sentinel network grew between October and late November. …”
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Assessing the efficacy of iso-mukaadial acetate and betulinic acid against selected Plasmodium falciparum glycolytic pathway proteins: in silico and in vitro studies by Lindiwe Khumbuzile Zuma, Ofentse Jacob Pooe, Nonduduzo Hlengiwe Mabaso, John Alake, Vincent A. Obakachi, Sinethemba Yakobi, Nothando Gasa, Rajshekhar Karpoormath, Mthokozisi Simelane

“…Meanwhile, PfHk-IMA had 0.39701 ± 0.16298 µM KD value, while the PfHk-BA complex had no interaction detected. Molecular docking and molecular dynamics simulation studies were used to measure and confirm the interactive strength of complexes. …”
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Antimicrobial Resistance and Biofilm-Forming Ability in ESBL-Producing and Non-ESBL-Producing <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> Isolated from Canine Urinary... by Alessia Facchin, Joel Filipe, Irene Mauri, Filippo Tagliasacchi, Guido Grilli, Tiziana Vitiello, Gabriele Ratti, Laura Musa, Martina Penati, Paola Scarpa, Stefania Lauzi

“…Thirty-four <i>E. coli</i>/<i>K. pneumoniae</i> isolates were detected, accounting for 26.5% of the examined samples. …”
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Pre-pandemic cross-reactive antibody and cellular responses against SARS-CoV-2 among female sex workers in Dakar, Senegal by Bobby Brooke Herrera, Bobby Brooke Herrera, Bobby Brooke Herrera, Bobby Brooke Herrera, Beth Chaplin, Souleymane MBoup, Adam Abdullahi, Adam Abdullahi, Michelle He, Sydney M. Fisher, Sulaimon Akanmu, Charlotte A. Chang, Donald J. Hamel, Ravindra K. Gupta, Ravindra K. Gupta, Phyllis J. Kanki

“…A unique pre-pandemic subject had cross-reactive SARS-CoV-2 S antibodies with detectable neutralization and cross-reactive cellular responses.ConclusionThese findings suggest that prior hCoV exposure may induce cross-reactive adaptive immunity, potentially contributing to protection against COVID-19. …”
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Clinical assessment of urinary prostate cancer antigen 3 in Chinese population: a large-scale, prospective and multicenter study by Xuan Shu, Jiaming Wang, Wen Cai, Shen Lin, Jiangfeng Li, Xueyou Ma, Yufan Ying, Yat Sai Terry Wang, Xiao Wang, Hong Chen, Chunyu Jin, Ben Liu, Liping Xie, Jindan Luo

“…The PCA3 score was analyzed by PCA3 gene expression Detection Kit (Fluorescent RT-PCR) (York biotech, Cat.…”
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Tear glucose is associated with the presence and severity of diabetic retinopathy by Ningyao Cao, Lili Feng, Wei Xu, Fanglin He, Caiwen Xiao, Yan Liu, Weirong Xu, Jingjing Cui, Yuqian Guo, Lianqing Yao, Wenwen Xia, Fei Chen, Yong Li, Chuandi Zhou, Xiaofang Xu

“…The performance of TG to detect DR was evaluated by the receiver operating characteristic (ROC) curve. …”
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SVM directed machine learning classifier for human action recognition network by Dharmanna Lamani, Pramod Kumar, A Bhagyalakshmi, J. Maria Shanthi, Lakshmana Phaneendra Maguluri, Mohammad Arif, C Dhanamjayulu, Sathish Kumar. K, Baseem Khan

“…In this paper, we offer HARNet, a specialized lightweight residual 3D CNN that is built on directed acyclic graphs and was created expressly to handle these issues and achieve effective human action detection. The suggested method presents an innovative pipeline for creating spatial motion data from raw video inputs, which makes successful latent representation learning of human motions easier to accomplish. …”
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Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2 by Charlotte Laurfelt Munch Rasmussen, Signe Frost Frederiksen, Christian Würtz Heegaard, Maj Schneider Thomsen, Eva Hede, Bartosz Laczek, Jakob Körbelin, Daniel Wüstner, Louiza Bohn Thomsen, Markus Schwaninger, Ole N. Jensen, Torben Moos, Annette Burkhart

“…Post-mortem analyses included gene expression analyses, verification of neurodegeneration in Purkinje cells, determination of NPC2 transduction in the CNS, assessment of gliosis, quantification of gangliosides, and co-detection of cholesterol with NPC2 in degenerating neurons. …”
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Clinically relevant orthotopic pancreatic cancer models for adoptive T cell transfer therapy by Gregory B. Lesinski, Chrystal M. Paulos, Maggie Phillips, Jacklyn Hammons, Isaac Karpovsky, Zaid Mahdi, Natalie K. Horvat, Megan M. Wyatt, Margaret A. Hall, Cameron J. Herting, Richard A. Moffitt

“…In contrast, far more host immune cells infiltrate the KPC-Luc tumors, which have less stroma, although CD4+ and CD8+ T cells were similarly detected in the MT-5 tumors compared with KPC-GEMM in mice. …”
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