Hypothyroidism is Not Associated with Keratoconus Disease: Analysis of 626 Subjects by Zsuzsa Flaskó, Elena Zemova, Timo Eppig, László Módis, Achim Langenbucher, Stefan Wagenpfeil, Berthold Seitz, Nóra Szentmáry

“…Patient eyes were classified (TKC) with dedicated, instrument-based, keratoconus detection software provided with the Pentacam. TKC = 0 was considered “normal,” and TKCs ≥ 1 were considered keratoconus. …”
Get full text

Antibacterial Potential of Endemic Medicinal Plants of the Maluku Islands, Indonesia, against Urinary Tract Infection Pathogens by Eka Astuty, Vinsa Delia Luhulima, Stefanus Cahyo Ariwicaksono

“…Further investigation is necessary to fully comprehend the mechanisms of action, detection, and description of bioactive compounds, particularly against human pathogens.…”
Get full text

The relation of MEFV gene variants to clinical phenotype and selected laboratory markers in Egyptian patients with familial Mediterranean fever by Hala T. El-Bassyouni, Ghada Nour Eldeen, Mona F. Sokkar, Mohamed B. Taher, Mohammed M. Sayed-Ahmed, Iman I. Salama, Hala M. Raslan

“…Genotyping of the MEFV gene demonstrated that 215 (71.2%) patients were heterozygotes, 26 (8.6%) patients were compound heterozygotes and 12 (4.0%) patients were homozygotes, while 49 (16.2%) patients had no detected mutation. p. Met 694Ile was the most common MEFV variant (36.7%), followed by p. …”
Get full text

Safety and efficacy of total colectomy with D3 lymph node dissection at colorectal cancer, developed at inflammatory bowel diseases (case control study) by P. V. Tsarkov, I. A. Tulina, S. K. Efetov, Yu. E. Kitsenko, D. N. Fedorov

“…Distant metastases were detected in 33.3% and 16.7% of IBD-CRC and spCRC cases respectively (p=0.4), without local recurrence in both groups. …”
Get full text

Non-Thermal Plasma-Activated Water Enhances Nursery Production of Vegetables: A Species-Specific Study by Silvia Locatelli, Stefano Triolone, Marina De Bonis, Giampaolo Zanin, Carlo Nicoletto

“…However, an increase in total N content was detected in plant tissues across all species, except for basil, where no change was observed. …”
Get full text

The role of PCBP1 in carbon ion-induced ferroptosis and inhibition of lung adenocarcinoma proliferation by Zhenchao Kang, Zihan Fu, Xuejiao Tian, Yichao Geng, Qiuning Zhang, Yanli Liu, Xinhua Wang, Hongtao Luo, Zhen Yang, Zhen Yang

“…ObjectiveTo investigate the role of PCBP1 in the inhibition of lung adenocarcinoma proliferation by carbon irradiation.MethodsA549 cells were irradiated with different doses of carbon ions to observe clonal survival and detect changes in cell proliferation. Whole transcriptome sequencing and the Illumina platform were used to analyze the differentially expressed genes in A549 cells after carbon ion irradiation. …”
Get full text

Associations between Age-Related Changes in the Core Vestibular Projection Pathway and Balance Ability: A Diffusion Tensor Imaging Study by Sang Seok Yeo, Jung Won Kwon, In Hee Cho

“…Statistically significant decrease in old adults was detected in the tract volume of lateral (p=0.005) and medial VST (p≤0.001) and PIVC (p=0.020). …”
Get full text

Anatomical characterization of Semi-arid Bignoniaceae using light and scanning electron microscopy by Romisha Sonia, Shabnum Shaheen, Muhammad Waheed, Sana Imran, Shiekh Marifatul Haq, Murad Muhammad, Abeer Hashem, Samiha Al Shehri, Elsayed Fathi Abd-Allah

“…Three patterns of anticlinal cell walls were detected: curved, straight, and sinuous. Distinct stomatal types were also identified across the different species. …”
Get full text

Reused N95 Face Masks Performance: Effect of Gamma Irradiation Method on Residual Bioburden and Functional Material Resistance by Ade Lestari Yunus, Akhmad Rasyid Syahputra, Rizka Fitriana, Deswita, Bimo Saputro, Muhamad Yasin Yunus, Hanna Yasmine, Devita Tetriana, Irawan Sugoro, Darmawan Darwis

Get full text

Assessment of risk factors for osteopenia development in premature babies by A. Yu. Tsymbal, Yu. V. Kotlova

“…Neonatal osteopenia (KB 61.3 (ICD-11)) – violation of mineral exchange of bone tissue (BT) of premature babies (PB). Predicting and detection of osteopenia is the key to its successful control. …”
Get full text

A Proteomic Study Based on Home Quarantine Model Identifies NQO1 and Inflammation Pathways Involved in Adenoid Hypertrophy by Chen P, Hou S, Pang X, Li L, Wei W

“…At the beginning of the COVID-19 pandemic, there was a significant reduction in the incidence of adenoid hypertrophy in children under long-term home quarantine, providing a rare research model to explore the pathogenesis and treatment targets of adenoidal hypertrophy in children.Methodology: Before and during the home quarantine period, adenoids that underwent surgery were detected using label-free proteomics. Differences in protein expression were analyzed using Gene Ontology, the Kyoto Encyclopedia of Genes and Genomes, Gene Set Enrichment Analysis, Protein-protein interaction, and immunohistochemistry analysis.Results: Long-term home quarantine had a profound impact on the proteomics of pediatric adenoids, with up-regulated and down-regulated proteins of 28 and 92 downregulated proteins, respectively. …”
Get full text

Transcriptome and DNA methylation profiling during the NSN to SN transition in mouse oocytes by Hannah Demond, Soumen Khan, Juan Castillo-Fernandez, Courtney W. Hanna, Gavin Kelsey

“…Transcriptome analysis showed a lower number of detected transcripts in SN compared with NSN oocytes as well as downregulation of 576 genes, which were enriched for processes related to mRNA processing. …”
Get full text

Prevalence and Associated Risk Factors of Soil-Transmitted Helminth Infections among Schoolchildren around Lake Tana, Northwest Ethiopia by Melsew Getaneh, Tamirat Hailegebriel, Abaineh Munshea, Endalkachew Nibret

“…Hookworm infection was the predominant STH infection, which was detected in 26.1% schoolchildren followed by A. lumbricoides (14.8%) and T. trichiura (1.5%). …”
Get full text

COMBINED TREATMENT OF LOCALLY-ADVANCED BLADDER CANCER by I. V. Chernyshev, Y. V. Samsonov, D. V. Perepechin, A. M. Ulbashev

“…There is an increasing proportion of detection of bladder cancer stage I–II disease patterns: 2003–50.8% in 2013–69.6%, while the number of newly diagnosed patients in III and IV clinical stages remains at 30%. …”
Get full text

Ex vivo biotransformation of lady’s mantle extracts via the human gut microbiota: the formation of phenolic metabolites and their impact on human normal and colon cancer cell lines... by Katarzyna Jakimiuk, Aleksandra Kruk, Marta Kinga Lemieszek, Jakub W. Strawa, Sebastian Granica, Adrian Wiater, Michał Tomczyk

“…The A. vulgaris herb metabolites were obtained by incubating the extract (AV) with human fecal slurries from three healthy donors (D1, D2, and D3).ResultsAfter incubating the AV extract with the human gut microbiota (AVD1-AVD3 samples), thirty-three metabolites were detected and characterized by LC-MS. Among them, one was identified as urolithin C. …”
Get full text

Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Nondialysis Chronic Kidney Patients by Gysllene M. C. Brito, Andrea M. M. Fontenele, Erika Cristina R. L. Carneiro, Iara Antonia L. Nogueira, Tamires B. Cavalcante, André A. M. Vale, Sally Cristina M. Monteiro, Natalino Salgado Filho

“…The best cutoff point for NLR to detect inflammation was 1.98, with 76.19% sensitivity and 48.44% specificity. …”
Get full text

Assessment of root resorption on lateral incisors after primary canine extraction treating mesioangular displaced permanent canines: a randomised controlled trial by Narmin Helal, Reem Naaman, Najlaa Alamoudi, Azza El-Housseiny, Fatima Jadu

“…Early clinical evaluation and consistent monitoring is essential for early detection and potential intervention in patients with mesioangular canine displacement.…”
Get full text

Heat shock transcription factor 1 facilitates liver cancer progression by driving super‐enhancer‐mediated transcription of MYCN by Yizhe Liu, Qili Shi, Yue Su, Zhiao Chen, Xianghuo He

“…Moreover, increased MYCN expression was detected in HCC tumors and correlated with unfavorable patient outcomes. …”
Get full text

Differential HLA Association of GAD65 and IA2 Autoantibodies in North Indian Type 1 Diabetes Patients by Neihenuo Chuzho, Neeraj Kumar, Neetu Mishra, Nikhil Tandon, Uma Kanga, Gurvinder Kaur, Paras Singh, Gunja Mishra, Shreya Sharma, Narinder K. Mehra

“…We evaluated the prevalence of GAD65 and IA-2 autoantibodies (GADA and IA2A) in 252 T1D patients from North India and investigated the genetic association of GADA and IA2A with HLA class I and class II genes/haplotypes. GADA and IA2A were detected in 50.79% and 15.87% of T1D patients, respectively, while only 8.73% had both GADA and IA2A. …”
Get full text

Myelitis associated with glial fibrillary acidic protein IgG: characterization and comparison with aquaporin-4 IgG and myelin oligodendrocyte glycoprotein IgG myelitis by Yinyin Xie, Wanwan Zhang, Aoya Han, Wenlin Sun, Xinru Zhou, Yi Xie, Yunqing Ma, Yajun Lian, Cui Wang, Nanchang Xie

“…Longitudinally sagittal T2 and gadolinium-enhancing spinal cord lesions were detected. Features favoring GFAP-IgG over the other types included presence of fever and neck stiffness, requirement of intensive care and mechanical ventilation, higher monocyte-to-lymphocyte ratio (MLR), presence of hyponatremia, markedly elevated CSF leukocyte counts, increased CSF total protein levels, and decreased CSF glucose levels. …”
Get full text