Quality Control of Fetal Wharton’s Jelly Mesenchymal Stem Cells-Derived Small Extracellular Vesicles by Krishnan I, Ng CY, Kee LT, Ng MH, Law JX, Thangarajah T, Zainuddin AA, Mahmood Z, Rajamanickam S, Subramani B, Lokanathan Y

“…Qualitatively, EVs-positive markers (CD63 and TSG101) and intact bilipid membrane vesicles were detected in all the sEV preparations. Quantitatively, the protein and particle concentrations revealed that all the sEV preparations were “impure” with < 1.5 × 109 particles/μg protein. …”
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Microbial Decontamination of Onion by Corona Discharge Air Plasma during Cold Storage by Eun Ha Chang, Yeoung Seuk Bae, Il Sheob Shin, Hyun Jin Choi, Ji Hyun Lee, Ji Weon Choi

“…The active species such as nitric oxide (NO) and nitric dioxide (NO2) were nearly detected in this experiment. CDAP treatment revealed different isolation frequencies depending on postharvest pathogens from diseased onions, showing less isolation frequency of Fusarium spp. and Alternaria sp. than that of Botrytis spp. when compared with untreatment onions during 10-month cold storage. …”
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PPAR-γ agonist mitigates intestinal barrier dysfunction and inflammation induced by Clostridioides difficile SlpA in vitro by Maryam Noori, Masoumeh Azimirad, Mahsa Ghorbaninejad, Anna Meyfour, Mohammad Reza Zali, Abbas Yadegar

“…Western blotting was performed to detect PPAR-γ level before and after adding its agonist, pioglitazone. …”
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Toxicity of nickel oxide nanoparticles in Capoeta fusca, using bioaccumulation, depuration, and histopathological changes by J. Kharkan, M.H. Sayadi, M. Hajiani, M.R. Rezaei, M. Savabieasfahani

“…Histopathological anomalies were detected in the fish exposed to nickel oxide nanoparticles. …”
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STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment by Walter J Storkus, Ronald J Fecek, Manoj Chelvanambi, Jennifer L Taylor

“…TLS formation in ADU S-100-treated mice was associated with the development of a highly oligoclonal TIL repertoire enriched in expanded T cell clonotypes unique to the TME and not detected in the periphery.Conclusions Our data support the premise that i.t. delivery of low-dose STING agonist promotes VN and a proinflammatory TME supportive of TLS formation, enrichment in the TIL repertoire and tumor growth control.…”
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Exosomal miR-122 derived from M2 macrophages induces osteogenic differentiation of bone marrow mesenchymal stem cells in the treatment of alcoholic osteonecrosis of the femoral hea... by Guoping Le, Riyou Wen, Huaixi Fang, Zhifa Huang, Yong Wang, Hanwen Luo

“…Subsequently, the effect of exosomal miR-122 on the osteogenic differentiation ability of BMSCs was detected, including cell proliferation, expression of osteogenic-related genes (RUNX2, BMP2, OPN, ALP), and calcium nodule formation. …”
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Enhancing furcation involvement classification on panoramic radiographs with vision transformers by Xuan Zhang, Enting Guo, Xu Liu, Hong Zhao, Jie Yang, Wen Li, Wenlei Wu, Weibin Sun

“…Cone-beam computed tomography (CBCT) enhanced diagnostic accuracy for detecting FI and measuring furcation defects. Despite its advantages, the high cost and radiation dose associated with CBCT equipment limited its widespread use. …”
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Aerobic exercise attenuates high-fat diet-induced glycometabolism impairments in skeletal muscle of rat: role of EGR-1/PTP1B signaling pathway by Liangzhi Zhang, Xiaojie Liu, Jing Hu, Helong Quan, Sang Ki Lee, Mallikarjuna Korivi, Lifeng Wang, Ting Li, Wei Li

“…RT-qPCR, western blot, and immunofluorescence were used to detect the EGR-1/PTP1B pathway and associated signaling molecules. …”
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Increased CCR7loPD-1hiCXCR5+CD4+ T Cells in Peripheral Blood Mononuclear Cells Are Correlated with Immune Activation in Patients with Chronic HBV Infection by Ya-Xin Huang, Qi-Yi Zhao, Li-Li Wu, Dong-Ying Xie, Zhi-Liang Gao, Hong Deng

“…The expression of CD4, CXCR5, PD-1, and CCR7 was detected in T cells from peripheral blood by flow cytometry. …”
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Biomarkers of gastric atrophy at stomach cancer by A. V. Belkovets, S. A. Kurilovich., Yu. I. Ragino, L. V. Scherbakova, O. B. Cheremisina, N. V. Cherdyntseva, N. A. Andryushina, M. I. Voyevoda

“…Significantly lower PGI scores were detected in SC patients with histologically verified atrophy. …”
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Resistance of spring bread wheat cultivars and lines to Septoria leaf blotch, tan spot, and spot blotch pathogens by Yu. V. Zeleneva, V. P. Sudnikovа, N. M. Kovalenkо, I. V. Gusev

“…The presence of the Tsn1 allele controlling susceptibility to the PtrToxA fungal toxin was detected using the Xfcp623 molecular marker.Results and conclusions. …”
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The study of miRNA-211 affects melanogenesis progress in Cashmere goats via suppressing <i>AP1S2</i> by B. Zhang, R. Liu, T. Ma, X. Li, Y. Zhao, H. Su, J. Li, Y. Li, H. Jiang, Q. Zhang

“…Furthermore, reduction in melanin content in the skin was detected. These results showed that miRNA-211 significantly affected the melanogenesis progress via downregulating <i>AP1S2</i> and advantageously affected the melanin content of Cashmere goat skin.…”
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Evaluation of recombinant proteins <i>T. pallidum</i> Тр0163 and Тр0971 as antigens for the diagnosis of syphilis using enzyme immunoassay by Natalia V. Arbuzova, Marina V. Shpilevaya, Georgii L. Katunin, Oleg E. Kuznetsov, Nikita Yu. Nosov, Viсtoria S. Solomka

“…In order to improve the treponema-specific diagnosis of syphilis, we believe it is important to continue working with these antigens to determine the effectiveness of ELISA to detect IgG, IgM or IgM/ IgG antibodies with a large number of clinical serum samples from syphilis patients, patients with non-syphilitic pathology and healthy individuals.…”
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Single-staged Surgical Correction of Kyphotic Deformity due to Dorsal Spinal Tuberculosis in Pediatric Patients: Outcome Analysis by Mageswaran Shanmugavelu, Makesh Ram Sriraghavan, Prabhu Aloy, Poornima Kumararaja, Sai Vinay Bharadwaj Namala

“…Development in the field of diagnostic methods and imaging has allowed us to detect TB of the spine in less advanced stages of the disease in most cases. …”
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Biopsy location and tumor-associated macrophages in predicting malignant glioma recurrence using an in-silico model by Pejman Shojaee, Edwin Weinholtz, Nadine S. Schaadt, Friedrich Feuerhake, Haralampos Hatzikirou

“…The current standard-of-care (SoC) for HGG includes follow-up neuroradiological imaging to detect recurrence as early as possible and relies on several clinical, neuropathological, and radiological prognostic factors, which have limited accuracy in predicting TTR. …”
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Comprehensive investigation of matrix metalloproteinases in skin cutaneous melanoma: diagnostic, prognostic, and therapeutic insights by Lingxia Wu, Chenxiaoxiao Liu, Weicai Hu

“…These MMPs could serve as biomarkers for early detection and targets for therapy. Future efforts should focus on preclinical and clinical validation to translate these insights into personalized diagnostic and therapeutic strategies.…”
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Maintenance of visual functions in patients with a scheduled cataract surgery by I.A. Il’inskaya, S.Yu. Kopaev

“…Additionally, a myopic shift of the spherical equivalent was detected. Significant differences (р&lt;0.001) were revealed in subgroup II, i.e., less changes in the spherical equivalent as compared with the control group and subgroup III. …”
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Connective tissue disease-associated interstitial lung disease – A multicenter observational study from India by Sham Santhanam, Pravin Patil, Mohit Goyal, C B Mithun, Parthajit Das, Kavitha Mohanasundaram, Neeraj Jain, Vijaya Prasanna, Keerthi Talari, Himanshu Pathak, Parshant Aggarwal, Deepika Ponnuru, Vikram Raj Jain, Sharath Kumar

“…Pulmonary hypertension (PH) was detected in 162 (35.8%) patients. The most common immunosuppressive used for lung disease was mycophenolate mofetil (54.0%) followed by azathioprine (19.5%). …”
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A common mechanism of detoxification for lambda-cyhalothrin and abamectin in Cydia pomonella by Di Ju, Chao Hu, Peirong Li, Ping Gao, Yuting Li, Xueqing Yang

“…Materials and methods To determine whether target-site insensitivity to LCT and AM plays a role in resistance, the sequences of voltage-gated sodium channel (VGSC) and glutamate-gated chloride channel (GluCl) containing the mutation domains were detected. To validate whether similar mechanisms were involved in the detoxification process of lambda-cyhalothrin (LCT) and abamectin (AM) at sublethal doses (specifically LD10 and LD30), cytochrome P450 monooxygenases (P450), glutathione S-transferases (GST), and carboxylesterases (CarE) activities were evaluated after insecticides exposure; synergistic experiments were conducted using piperonyl butoxide (PBO), diethyl maleate (DEM), and triphenyl phosphate (TPP) as inhibitors of P450, GST, and CarE respectively. …”
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Predicting Poor Outcome of COVID-19 Patients on the Day of Admission with the COVID-19 Score by Luke Tseng, Erin Hittesdorf, Mitchell F. Berman, Desmond A. Jordan, Nina Yoh, Katerina Elisman, Katherine A. Eiseman, Yuqi Miao, Shuang Wang, Gebhard Wagener

“…COVID-19 may result in multiorgan failure and death. Early detection of patients at risk may allow triage and more intense monitoring. …”
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