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22821
Inhibition of mPFC norepinephrine improved chronic post-thoracotomy pain in adult rats
Published 2025-12-01“…Norepinephrine in mPFC microdialysates were determined by high performance liquid chromatography with electrochemical detection (HPLC-ECD). The mPFC was collected to assess norepinephrine synthase (dopamine beta-hydroxylase, DβH) and metabolic enzyme (monoamine oxidase A/B, MAO-A/B and catechol-O-methyltransferase, COMT), bradykinin, bradykinin receptor 2 (Bdkrb2), neuroinflammation (Iba1, IL-6 and TNF-α), Aquaporin-4 (AQP4) and IL-33.Results Right thoracotomy reduced the mechanical withdrawal threshold and cold pain threshold around incision, the expression of AQP4 and IL-33, increased norepinephrine, DβH, bradykinin, Bdkrb2, Iba1 and IL-6, but had no impact on MAO-A, MAO-B, COMT and TNF-α in contralateral mPFC. …”
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22822
Association between colorectal cancer and arthritis among Americans in 2005–2016
Published 2025-01-01“…Conclusion This study found that arthritis had a strong association with the occurrence of CRC, providing ideas and strategies for its early detection.…”
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22823
HCV and HIV co-infection among people who inject drugs in Vietnam
Published 2020-12-01“…Four mutually exclusive groups were defined based on the presence of detectable HCV RNA and positive HIV confirmation. Multiple logistic regression analyses were performed to explore life-time risk behaviors of HCV mono-infection and HIV/HCV co-infection. …”
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22824
Effects of community-wide vaccination with PCV-7 on pneumococcal nasopharyngeal carriage in the Gambia: a cluster-randomized trial.
Published 2011-10-01“…No significant serotype replacement was detected. Please see later in the article for the Editors' Summary.…”
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22825
The relationship between dietary inflammatory index (DII) and early renal injury in population with/without hypertension: analysis of the National health and nutrition examination...
Published 2024-12-01“…Furthermore, an interaction between DII and hypertension was detected in eGFRs&c (OR:1.250[1.042, 1.499], p for interaction = 0.03).Conclusion Higher levels of DII may be associated with occurrence of early kidney damage. …”
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22826
L-shaped association of body mass index with prognosis in individuals with sepsis: a multicenter cohort study
Published 2025-02-01“…We performed the log-rank test to detect whether there is a difference in prognosis among different groups in two different cohorts. …”
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22827
Cutaneous Anthrax: What is the Hallmark?
Published 2024-10-01“…Clinical and serological examinations are the spearheads of early detection of anthrax cases. Prompt and appropriate management largely determines the success of therapy.…”
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22828
Metformin Ameliorates Ulcerative Colitis Through Inhibiting NLRP3 Inflammasome Activation
Published 2025-02-01“…Enzyme-linked immunosorbent assay (ELISA), Reverse transcription - quantitative polymerase chain reaction (RT-qPCR), Western blotting (WB), immunohistochemistry, and immunofluorescence were used to detect NLRP3 inflammasome activation in vivo. Furthermore, in vitro, bone marrow-derived macrophages (BMDMs) selected to clarify the role of Met on NLRP3 inflammasome activation and the underlying mechanisms.Results: In vivo, Met could significantly inhibit the development of UC, characterized by decreased DAI, increased body weight and colorectal length, and the repair of damaged tissue. …”
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22829
An association between type A porcine endogenous retrovirus copy number and hematological parameters and gender in miniature pigs
Published 2017-12-01“…No correlation between PERV-A env gene copy number and the coat color of animals was detected, suggesting that retroviral insertion sites and genes that determine the coat color of miniature pigs, namely KIT (chromosome 8) and MC1R (chromosome 6), are either located far apart on same chromosome or on different chromosomes. …”
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22830
Effect and Mechanism of Catalpol on Behavior in Rats with Post-stroke Depression
Published 2022-02-01“…TTC staining was used to detect cerebral infarction volume. The serum and hippocampus levels of 5-HT, NE, and BDNF were measured by enzyme-linked immunosorbent assay.ResultsCompared with the model group, the number of crossing grid, the number of standing and the total distance moved were significantly increased on the 4th and 7th day after intervention in the open field test, and the differences were significant (<italic>P</italic><0.05). …”
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22831
Prevalence and Risk Factors Associated with S. haematobium Egg Excretion during the Dry Season, Six Months following Mass Distribution of Praziquantel (PZQ) in 2017 in the Bafia He...
Published 2019-01-01“…Schistosoma haematobium ova in urine were detected using membrane filtration technique. Results. …”
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22832
Next-Generation Sequencing Analysis on Image-Guided Biopsy Samples in Early-Stage Lung Cancer: Feasibility Study and Comparison With Surgical Samples
Published 2025-02-01“…We compared NGS feasibility and quality between biopsy methods and, for those with NGS on surgical samples, compared feasibility, quality, and detection of actionable variants. Results: Among the 654 participants with lung tumors of 30 mm or less who underwent surgery, 70 had NGS on prior biopsies. …”
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22833
The Assessment of Different Dietary Selenium Resources on Reproductive Performance, Spawning Indicators, and Larval Production of Red Tilapia (Oreochromis mossambicus × O. niloticu...
Published 2023-01-01“…At the same time, the highest levels of LH, progesterone, and estradiol-17β, as well as the lowest levels of FSH, were detected in fish fed the NPSe diet, followed by those on the Na2SeO3 + NPSe and Na2SeO3 diets, respectively. …”
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22834
The role of long non-coding RNA LINC00839 in oral squamous cell carcinoma based on bioinformatics and experimental research
Published 2024-12-01“…Different online tools were applied to detect lncRNA-related miRNAs and their target mRNAs, forming a lncRNA/miRNA/mRNA axis. …”
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22835
Genetic polymorphism of CYP1A1 and CYP2D6 in populations of Buryats, Teleuts and Russians of Eastern Siberia
Published 2018-04-01“…The CYP2D6*3 (2549del) allele was not detected in cohorts of indigenous populations, among Russians it was 0.4 %, and it was 2.7 % among Métis. …”
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22836
The BASIDIN effector of the fungus Moniliophthora perniciosa promotes positive effects on the seed germination and seedlings development of Lactuca sativa
Published 2025-01-01“…The lowest electrolyte leakage was detected in seeds treated with the three concentrations of rBASIDIN compared to the controls. …”
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22837
Risk factors for mediastinal lymph node metastasis and lung metastasis in papillary thyroid carcinoma patients: who benefits from preoperative computed tomography?
Published 2024-04-01“…MLNM and lung metastases were detected in 1.2% and 3.3% of patients, respectively. cT3-4, cN1, central LN metastasis, and lateral LN metastasis were RFs for MLNM in all patients (p < 0.05, p < 0.05, p < 0.05, p < 0.01) and older patients (age: ≥55 years) (p < 0.01, p < 0.05, p < 0.05, p < 0.05). cT3-4, cN1, gross extrathyroidal extension, central LN metastasis, and lateral LN metastasis were RFs for lung metastasis in all patients (p < 0.01, p < 0.05, p < 0.01, p < 0.01, p < 0.01, respectively). cN1 and gross extrathyroidal extension, central LN metastasis, and lateral LN metastasis were RFs in older patients (p < 0.01, p < 0.01, p < 0.05, p < 0.01), while lateral LN metastasis was an RF for lung metastasis in those of <55 years of age (younger patients) (p < 0.05). …”
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22838
Longitudinal Assessment of Alterations in Peripheral Inflammatory Markers Over a Hospitalization Period in Patients with Schizophrenia
Published 2023-12-01“…Future studies should explore the potential of markers like CAR and SII in detecting low-grade inflammation, and further probe into the role of sleep, nutrition, and physical activity, emphasising the paramount role of comprehensive hospital care.…”
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22839
Bridging past and present: exploring Cannabis traditions in Armenia through ethnobotanical interviews and bibliographic prospecting
Published 2025-01-01“…The loss of vernacular names over time, as detected in this study, also reflects the erosion of traditional knowledge, which correlates with diminishing use. …”
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22840
Cognitive Performance in Hot-Humid Environments of Non-Air-Conditioned Buildings: A Subjective Evaluation
Published 2024-12-01“…Furthermore, a quasi-inverted-U relationship was observed between the positive mood and exposure time, while a quasi-U relationship between the negative mood and exposure time was detected. Finally, a performance-mood relation was established based on the correlation analysis among the CPI, mood, and mental workload, which produced a linear relation with the R<sup>2</sup> of 0.71. …”
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