Novel molecular biomarkers of cancer therapy‐induced cardiotoxicity in adult population: a scoping review by Irene Cartas‐Espinel, Marcelino Telechea‐Fernández, Carlos Manterola Delgado, Andrés Ávila Barrera, Nicolás Saavedra Cuevas, Angela L. Riffo‐Campos

“…Abstract Aim Cancer treatments are associated with cardiotoxic events that predispose to cardiac pathology and compromise the survival of patients, making necessary the identification of new molecular biomarkers to detect cardiotoxicity. This scoping review aims to identify the available evidence on novel molecular biomarkers associated with cardiotoxicity in the adult population undergoing cancer therapy. …”
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Reliability and Validity of the ActivForce Digital Dynamometer in Assessing Shoulder Muscle Force across Different User Experience Levels by Christos Karagiannopoulos, Sean Griech, Brian Leggin

“… # Hypothesis/Purpose This study aimed to determine the AF intra- and inter-tester reliabilities, standard error of measurement (SEM), minimal detectable change (MDC), and criterion validity for assessing shoulder isometric force as compared to the microFET2 (MF2) across testers with different experiences…”
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Machine Learning-Based predictive model for adolescent metabolic syndrome: Utilizing data from NHANES 2007–2016 by Yu-zhen Zhang, Hai-ying Wu, Run-wei Ma, Bo Feng, Rui Yang, Xiao-gang Chen, Min-xiao Li, Li-ming Cheng

“…Abstract Metabolic syndrome (Mets) in adolescents is a growing public health issue linked to obesity, hypertension, and insulin resistance, increasing risks of cardiovascular disease and mental health problems. Early detection and intervention are crucial but often hindered by complex diagnostic requirements. …”
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Clinical and Hematological Manifestation of Dengue Patients in 2022 Outbreak: A Tertiary Care Hospital‐Based Cross‐Sectional Study by Md. Jubayer Hossain, Manisha Das, Muhibullah Shahjahan, Md. Wahidul Islam, Syeda Tasneem Towhid

“…Enhancing physician awareness regarding dengue case detection and management, along with routine dengue testing, are recommended for early diagnosis and improved patient outcomes.…”
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Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis by Anqi Wang, Sitong Yan, Weijia Jiang, Xiang Chen, Yuhan Huang, Xiangyu Zu, Xiao Du, Lulu Fan, Jiatao Liu, Guoping Sun

“…CCK-8, colony formation, EdU staining, wound-healing, Transwell, western blotting and RT-qPCR were used to detect the effects of CLIP4 on the proliferation, migration and epithelial-mesenchymal transition (EMT) of HCC cells. …”
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Airborne radiometric data for digital soil mapping of peat at broad and local scales by Dave O’Leary, Colin Brown, Jim Hodgson, John Connolly, Louis Gilet, Patrick Tuohy, Owen Fenton, Eve Daly

“…Validation is performed using Loss on Ignition (LOI %) point data and several different (blanket bog, raised bog, transition zone) sites in Ireland, showing classified data can detect the presence of peat soils from broad to local scales. …”
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Gyrfalcon Prey Abundance and Their Habitat Associations in a Changing Arctic by Michaela Gustafson, Jennifer D. McCabe, Brian W. Rolek, Travis L. Booms, Michael T. Henderson, Leah Dunn, David L. Anderson, Jennyffer Cruz

“…We aimed to determine the habitat–abundance relationships for three small herbivores on the Seward Peninsula of Alaska, USA by fitting data from 983 point counts (collected during 2019, 2021, and 2022) with N‐mixture models that account for imperfect detection. These herbivore species, Willow Ptarmigan (Lagopus lagopus), Rock Ptarmigan (L. muta), and Arctic ground squirrels (Urocitellus parryii), are fundamental to tundra food webs, and primary prey for Arctic raptors including Gyrfalcons (Falco rusticolus). …”
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Retrospective study of spontaneous subarachnoid haemorrhage: vasospasm and other complications (Part III) by S. Bakanauskaitė, J. Grigaitė, R. Danilevičienė, G. Lizaitienė, L. Piliponis, J. Ščerbak, D. Jatužis, J. Valaikienė

“…One of the main causes of mortality is cerebral vasospasm (CVS), a cause of delayed cerebral ischaemia (DCI), which can lead to secondary cerebral infarction. Thus, early detection of CVS is crucial for improving patient outcomes. …”
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Assessment of Tumor Response to Neoadjuvant Chemotherapy in Breast Cancer Using MRI and 18F FDG PET/CT by Reem Yusuf AlBuainain, Fatema Yusuf Bunajem, Hussain Adnan Abdulla

“…The aim of this study was to assess tumor response to NACT by MRI and PET/CT, to determine which imaging modality is more accurate in detecting tumor response post NACT in breast cancer. …”
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Factors influencing endometrial receptivity in women with recurrent implantation failure by Katarzyna Opuchlik, Katarzyna Pankiewicz, Piotr Pierzyński, Janusz Sierdziński, Elina Aleksejeva, Andres Salumets, Tadeusz Issat, Piotr Laudański

“…Results In women with RIF pre-receptive endometrium has been detected substantially more often than in controls − 13 (19,1%) vs. 3 (6,1%) patients (p = 0,043). …”
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Subclinical imaging activity in multiple sclerosis patients during war‐related psychological stress by Omri Zveik, Tal Friedman‐Korn, Ariel Rechtman, Tal Ganz, Garrick Hoichman, Lyne Shweiki, Dana Ekstein, Adi Vaknin‐Dembinsky

“…Interpretation This study provides evidence of increased MRI‐detected disease activity in pwMS during periods of war‐related psychological stress. …”
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Conceptual foundations of a REFRAME-based approach to discriminate across total knee implant designs based on the positions of functional centres of rotation by Adrian Sauer, Ariana Ortigas-Vásquez, Christoph Thorwaechter, Peter E. Müller, Henning Windhagen, Allan Maas, Thomas M. Grupp, William R. Taylor, Matthias Woiczinski

“…The kinematic signals of these five configurations were compared to determine whether key differences between implants could be detected leveraging two methodological approaches: (1) statistical parametric mapping to directly compare waveforms and (2) simple paired t-tests to compare the three-dimensional coordinates of the functional centres of rotation determined using a previously published REference FRame Alignment Method (REFRAME). …”
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Expression and Function of Synthetic Dimeric Exercise-Induced Cytokine Irisin-Irisin by LIU Fengying, HUANG Yide, LIN Jia, CHEN Xuequn, WANG Qingshui, LIN Yao

“…The functions were verified in gastric cancer, colorectal cancer and other gastrointestinal tumors, and the activity and function of recombinant Irisin-Irisin and monomeric Irisin on tumor cells were compared.Results(1) Expression and purification of recombinant Irisin-Irisin: compared with the non-induced samples, the recombinant Irisin-Irisin was significantly expressed after IPTG induction; high purity recombinant Irisin-Irisin with a molecular weight of about 27 kDa was obtained by Ni Sepharose excel. (2) Detection of recombinant Irisin-Irisin activity: compared with the blank control group, both the recombinant Irisin-Irisin group and the Irisin group could up-regulate the expression of UCP-1 in C2C12 cells (<italic>P</italic>&lt;0.05); compared with the Irisin group, the recombinant Irisin-Irisin group had a more significant effect and stronger activity in inducing UCP-1 (<italic>P</italic>&lt;0.05). (3) Recombinant Irisin-Irisin on tumor function: compared with the blank control group, both the 100 ng/mL and 200 ng/mL Irisin-Irisin groups could inhibit the migration of gastric cancer cells and colorectal cancer cells(<italic>P</italic>&lt;0.05), but had no effect on their proliferation and clone formation; compared with the Irisin group, the recombinant Irisin-Irisin group had a more significant effect on cell migration inhibition (<italic>P</italic>&lt;0.05).ConclusionThe recombinant Irisin-Irisin expressed by <italic>Escherichia coli</italic> has activity, and the activity is higher than that of the monomeric Irisin; recombinant Irisin-Irisin has an effect on the migration of gastric cancer cells and colorectal cancer cells, and the effect was better than that of the monomeric Irisin.…”
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Astrocyte-Derived Interleukin 11 Modulates Astrocyte–Microglia Crosstalk via Nuclear Factor-κB Signaling Pathway in Sepsis-Associated Encephalopathy by Dandan Zhu, Peng Wang, Xiyue Chen, Kaituo Wang, Yunsong Wu, Min Zhang, Jianhua Qin

“…Upon LPS exposure for astrocytes, we detected that more microglia migrated to the central astrocyte culture compartment on the microfluidic device, accompanied by M1 polarization and increased cell motility in microglia. …”
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Preferential Expression of B7-H6 in Glioma Stem-Like Cells Enhances Tumor Cell Proliferation via the c-Myc/RNMT Axis by Hanqing Chen, Yundi Guo, Jing Sun, Jun Dong, Qinghua Bao, Xueguang Zhang, Fengqing Fu

“…Intriguingly, B7-H6 was rarely detected on the surface of glioma cell lines but was abundantly expressed in glioma stem-like cells (GSLCs) that were derived from the glioma cell lines in vitro. …”
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MORPHOFUNCTIONAL CHARACTERISTICS OF LEAVES AND FRUITS IN MALOIDEAE (ROSACEAE): b. THE ROLE OF SURFACE TISSUES IN THE FORMATION OF RESISTANCE TO FUNGAL DISEASES by T. Kh. Kumachova, O. O. Beloshapkina, A. S. Voronkov, A. S. Ryabchenko

“…Condensed polyphenols were detected using K2Cr2O7 and FeCl3 as well as 4-(Dimethylamino)cinnamaldehyde (DMACA, Sigma-Aldrich).Results. …”
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Treatment decision regret after precision prostatectomy: An analysis of patient‐reported outcomes predicting decision regret by Kaushik P. Kolanukuduru, Wooju Jeong, Larisa Pistin, Firas Abdollah, Ash K. Tewari, Mani Menon

“…Given the subtotal nature of the surgery, patients were informed about the possibility of a detectable prostate‐specific antigen and secondary treatment. …”
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The Genetic Expression Difference of A2058 Cells Treated by Plasma Direct Exposure and Plasma-Treated Medium and the Appropriate Treatment Strategy by Chao-Yu Chen, Chung-Hsien Chou, Yun-Chien Cheng

“…However, there was no significant increase in the concentration of HTA in culture medium. HTA was detected in the treatment interface of PBS but not medium, showing the penetration of •OH through PBS. …”
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Effect of cytotoxic CD8+ T-cells secretory proteins on hypoxic pancreatic cancer cells. by Eiman Abdo, Mohammad A Ismail, Sabal Al Hadidi, Mairvat Al-Mrahleh, Tareq Saleh, Malik Zihlif, Nidaa A Ababneh

“…A significant decrease in TNF-α and IFN-γ levels was also detected. Additionally, a significant increase in IL-6, p53 and TNF-α gene expression levels was observed in PANC-1 cells treated with CD8+ T-cells CM. …”
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Ultra-fast biparametric MRI in prostate cancer assessment: Diagnostic performance and image quality compared to conventional multiparametric MRI by Antonia M. Pausch, Vivien Filleböck, Clara Elsner, Niels J. Rupp, Daniel Eberli, Andreas M. Hötker

“…Both readers demonstrated high sensitivity (≥94 %/≥91 %, R1/R2) and NPV (≥96 %/≥95 %) for csPCa detection using both protocols. The more experienced reader mostly showed notably higher specificity (≥77 %/≥53 %), PPV (≥62 %/≥45 %), and diagnostic accuracy (≥82 %/≥65 %) compared to the less experienced reader. …”
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