Discrepancies between preoperative diagnosis of tumors and the right uterine appendage and intraoperative data. Appendiculare mucocele, which manifests itself in the form of an app... by V.О. Sklyarovа, R.A. Chajkivskyj, O.V. Prykupenko, P.O. Sklyarov, V.R. Chajkivska

“…Intraoperatively Intact 2 fallopian tubes were detected, a tumor formation of the appendix 3-2-3 cm without adhesions was isolated. …”
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Association of genetically proxied cancer-targeted drugs with cardiovascular diseases through Mendelian randomization analysis by Chuchun Fang, Xuewei Liu, Chen Yu, Songlin Li, Xueying Liu, Shifeng Qiu, Hongbin Liang, Caiwen Ou, Jiancheng Xiu

“…Results Among the 39 drug target genes, 8 were identified with detectable cis-eQTLs and were subsequently validated through positive control analysis for further investigation. …”
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The Impact of Pelvic Floor Muscle Strengthening on the Functional State of Women Who Have Experienced OASIS After Childbirth by Atėnė Simanauskaitė, Justina Kačerauskienė, Dalia Regina Railaitė, Eglė Bartusevičienė

“…<i>Results:</i> OASIS were detected in 13 (0.4%) women in 2021. Risk factors for OASIS were found to be fetal macrosomia (<i>p</i> = 0.012), fetal occiput posterior position (<i>p</i> = 0.001), and epidural analgesia (<i>p</i> = 0.003). …”
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Exploration and characterization of lipid-degrading bacteria from palm oil mill effluent by P. Periadnadi, N. Nurmiati, F.W. Siregar, T.W. Edelwis

“…Therefore, this study aimed to identify potential bacteria, assess the in vitro lipid-degrading capabilities, characterize the traits, and evaluate lipid degradation activity of potential isolates from palm oil industry wastewater.METHODS: The method used for exploring the potential of lipid-degrading bacteria in palm oil mill effluent entailed a survey comprising various stages including detection of bacteria presence, in vitro assessment of potential indices, characterization, lipid degradation testing, and determination of lipase activity.FINDINGS: The results showed that several bacteria groups were present in palm oil mill effluent, including 50-74 percent lipolytic, 31-90 percent fermentative, 76-83 percent proteolytic, and 51-74 percent cellulolytic. …”
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Clinical Value and Potential Mechanism of miRNA-33a-5p in Lung Squamous Cell Carcinoma by Xiang-Ming Wang, Shang-Wei Chen, Gang Chen, Hua-Fu Zhou, Ting-Qing Gan, Jing-Jing Zeng, Zu-Yun Li

“…This study is aimed at thoroughly exploring the expression status, clinical significance, and underlying molecular mechanism of miRNA-33a-5p in lung squamous cell carcinoma (LUSC). Here, we detected miRNA-33a-5p in 20 samples from patients with LUSCs and 20 matching non-LUSC specimens by in-house quantitative real-time PCR (RT-qPCR). …”
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Potential biomarkers and immune infiltration linking endometriosis with recurrent pregnancy loss based on bioinformatics and machine learning by Jianhui Chen, Qun Li, Xiaofang Liu, Fang Lin, Yaling Jing, Jiayan Yang, Lianfang Zhao

“…This study aims to investigate the potential biomarkers and immune infiltration in EMs and RPL, providing a basis for early detection and treatment of the two diseases.MethodsTwo RPL and six EMs transcriptomic datasets from the Gene Expression Omnibus (GEO) database were used for differential analysis via limma package, followed by weighted gene co-expression network analysis (WGCNA) for key modules screening. …”
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Preclinical studies of the falnidamol as a highly potent and specific active ABCB1 transporter inhibitor by Baojie Liu, Yongzheng Lu, Ruihui Lin, Junbao Xu, Zilin Shang, Xinyu Hou, Xulong Shao, Zhifang Pan, Tao Yu, Weiguo Feng

“…The ATPase activity of ABCB1 was detected by a microplate reader. The interaction between falnidamol and ABCB1 was evaluated by docking analysis and cellular thermal shift assay. …”
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Assessment of Microbiological Indoor Air Quality in Cattle Breeding Farms by Justyna Szulc, Małgorzata Okrasa, Katarzyna Dybka-Stępień, Michael Sulyok, Adriana Nowak, Anna Otlewska, Bogumiła Szponar, Katarzyna Majchrzycka

“…The microbial population measured in the air and that in the settled dust exhibited a linear relationship, with an R2 of 0.8349–0.9471. We detected 172 and 210 bacterial/archaeal genera and 89 and 43 fungal genera in the dust and in the air, respectively. …”
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Evaluation of Fundus Function in Mature Cataract Patients by Visual Electrophysiology by Min Zhang, Min Ji, Mengjia Tan, Ying Yu, Huaijin Guan

“…Conclusions. ffERG and mfERG can be used to detect fundus disease in mature cataract patients. …”
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Device and Methods for Measuring of Acoustic Anisotropy and the Residual Stress in the Main Gas Pipelines’ Metal by L. V. Volkova, O. V. Murav’eva, V. V. Murav’ev, I. V. Buldakova

“…For samples with stress corrosion cracking a sharp decrease in the anisotropy coefficient is observed which makes it possible to use the indicated characteristics as informative parameters in detecting stress corrosion cracking.A feature of the proposed methods is high accuracy, due to the absence of necessity to determine the material density and precision measurement of its thickness, the measurement error of which is significant by known methods.Keywords: main gas pipeline, elastic moduli, acoustic anisotropy of properties, the biaxial stress-strain state, longitudinal and transversal waves.…”
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Betacoronaviruses Differentially Activate the Integrated Stress Response to Optimize Viral Replication in Lung-Derived Cell Lines by David M. Renner, Nicholas A. Parenti, Nicole Bracci, Susan R. Weiss

“…We demonstrate that MERS-CoV, HCoV-OC43, and SARS-CoV-2 all activate PERK and induce responses downstream of p-eIF2α, while only SARS-CoV-2 induces detectable p-eIF2α during infection. Using a small molecule inhibitor of eIF2α dephosphorylation, we provide evidence that MERS-CoV and HCoV-OC43 maximize viral replication through p-eIF2α dephosphorylation. …”
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The Risk Assessment of Pesticide Ingestion with Fruit and Vegetables for Consumer’s Health by Gordana Jurak, Jasna Bošnir, Domagoj Đikić, Ana Mojsović Ćuić, Iva Pavlinić Prokurica, Aleksandar Racz, Tomislav Jukić, David Stubljar, Andrej Starc

“…Study results revealed imazalil to be the most frequently detected pesticide. Risk assessment was performed on the obtained results, and it was carried out separately for adults and for children under 6 years of age. …”
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JNK Signaling Pathway Suppresses LPS-Mediated Apoptosis of HK-2 Cells by Upregulating NGAL by Mei Han, Yuxia Pan, Mengying Gao, Junli Zhang, Fan Wang

“…NGAL and caspase-3 gene expression levels were detected by RT-PCR to assess dynamic changes. HK-2 cells were pretreated with SP600125 (20 μM) for 2 hours, followed by LPS (10 μM) stimulation for 3 hours. …”
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Life-history traits, pace of life and dispersal among and within five species of Trichogramma wasps: a comparative analysis by Guicharnaud, Chloé, Groussier, Géraldine, Beranger, Erwan, Lamy, Laurent, Vercken, Elodie, Dahirel, Maxime

“…There was limited variation in effective dispersal between species and lines, and accordingly, we did not detect any correlation between effective dispersal probability and life-history traits. …”
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Dynamically triggered seismicity in Japan following the 2024 M w 7.5 Noto earthquake by Like An, Bogdan Enescu, Zhigang Peng, Masatoshi Miyazawa, Hector Gonzalez-Huizar, Yoshihiro Ito

“…Local earthquakes are detected on high-pass filtered three-component seismograms. …”
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Blood Lipid Levels and Their Value as Markers of Disease Activity in Severe Ulcerative Colitis by Zhu L, Tian L, Li S, Huo L

“…Patients with severe versus non-severe UC had decreased TC, HDL-C, LDL-C, and non-HDL-C levels (P< 0.05). The combined detection of TC level and erythrocyte sedimentation rate (ESR) predicted a working characteristic receiver operating characteristic curve area of 0.768 (0.694– 0.841) in patients with severe UC, which had good early predictive value with a sensitivity of 77.0% and specificity of 66.7%.Conclusion: TC, HDL-C, LDL-C, and non-HDL-C levels were decreased in patients with severe UC. …”
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A Simple Nomogram for Predicting the Development of ARDS in Postoperative Patients with Gastrointestinal Perforation: A Single-Center Retrospective Study by Zhang Z, Zhao H, Zhang Z, Jia L, Long L, Fu Y, Du Q

“…This study aims to develop a predictive model for ARDS in postoperative patients with gastrointestinal perforation to facilitate early detection and effective prevention.Methods: In this single-center retrospective study, clinical data were collected from postoperative patients with gastrointestinal perforation admitted to the ICU in Hebei Provincial People’s Hospital from October 2017 to May 2024. …”
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Comparative Analysis of Tenogenic Gene Expression in Tenocyte-Derived Induced Pluripotent Stem Cells and Bone Marrow-Derived Mesenchymal Stem Cells in Response to Biochemical and B... by Feikun Yang, Dean W. Richardson

“…Western blotting revealed that TGF-β3 and BMP12 increased the expression of transcription factors SCX and MKX in both cells, but the tenocyte marker tenomodulin (TNMD) was detected only in BMSCs and upregulated by either inducer. …”
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Greener and rapid magnetic solid phase microextraction method using Fe3O4@Al2O3/AC for chromatographic determination of neonicotinoid pesticides in vegetable oils by Musiiwa V. Sengane, Masixole Sihlahla, Philiswa N. Nomngongo, Nomvano Mketo

“…Additionally, the obtained limit of detection (LOD) ranged from 0.5–1.76 ng µL-1, the limit of quantification (LOQ) ranged from 1.87–6.62 ng µL-1 and satisfactory high preconcentration factors (73.02- 407.0) were comparable with literature reported studies. …”
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Molecular characterization and genome sequencing of selected highly resistant clinical isolates of Pseudomonas aeruginosa and its association with the clustered regularly interspac... by Hekmat A. Owaid, Mushtak T.S. Al-Ouqaili

“…The objective was to detect the prevalence of CRISPR in extensively and pan-drug-resistant Pseudomonas aeruginosa and to determine the utility of whole-genome sequencing (WGS) for the analysis of the entire genome for such strains. …”
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