The Clinical and Economic Burden of Colorectal Anastomotic Leaks: Middle-Income Country Perspective by Ulysses Ribeiro Jr., Daiane O. Tayar, Rodrigo A. Ribeiro, Priscila Andrade, Silvio M. Junqueira Jr.

“…Generalized linear models (GLM) were employed to evaluate the association between AL and continuous outcomes (LOS and costs). Results. AL was detected in 6.8% of the patients. Emergency surgery (aRR 2.56; 95% CI: 1.15–5.71, p=0.021), blood transfusion (aRR 4.44; 95% CI: 1.86–10.64, p=0.001), and cancer diagnosis (aRR 2.51; 95% CI: 1.27–4.98, p=0.008) were found to be independent predictors of AL. …”
Get full text

Assessment of Physicochemical Characteristics of Produced Water from Terminals of Some Oil Industry Facilities in Nigeria by CC Obunwo, C Chukwudi

“…Levels of trace metals ( Pb, Ni, V, Cd, Hg and Cr) were below detection limits. However, the concentration of Fe ranged between 0.53 ± 0.11mg/l 1.06 ± 0.26mg/l. …”
Get full text

The sporophytic type of fertility restoration in the A3 CMS-inducing cytoplasm of sorghum and its modification by plant water availability conditions by L. A. Elkonin, V. V. Kozhemyakin, M. I. Tsvetova

“…For the first time, the transgenerational effect of water availability conditions of growing a fertility-restoring line on male fertility of the F2 generation was detected: a pollinator grown in a plot with additional irrigation produced more fertile and less sterile individuals compared to the same pollinator grown under a rainfall shelter (p < 0.01), and the segregation pattern changed from digenic to monogenic, indicating heritable inhibition of the expression of one of the fertility-restoring genes (kind of “grandfather effect”). …”
Get full text

The drivers of mental health service utilisation among public primary healthcare workers in Negeri Sembilan. by Norhafizah Mohd Noor, Ahmad Azuhairi Ariffin, Halimatus Sakdiah Minhat, Lim Poh Ying, Umi Adzlin Silim

“…To sustain high levels of MHSU, it is essential to implement regular mental health training targeted HCWs with lower to middle household incomes and those experiencing low supervisor support, while simultaneously enhancing co-worker support and screening program for early detection of mental health problems.…”
Get full text

Next generation bioelectronic medicine: making the case for non-invasive closed-loop autonomic neuromodulation by Imanuel Lerman, Yifeng Bu, Rahul Singh, Harold A. Silverman, Anuj Bhardwaj, Alex J. Mann, Alik Widge, Joseph Palin, Christopher Puleo, Hubert Lim

“…We emphasize both invasive techniques, such as implantable devices for brain, spinal cord and autonomic regulation, while we introduce new prospects for non-invasive neuromodulation, including focused ultrasound and newly developed autonomic neurography enabling precise detection and titration of inflammatory immune responses. …”
Get full text

Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types by Gou XJ, Li LF, He XL, Chen X, Yu AY, Tian WY

“…Both blood pressure and SI enhanced significantly after transfusion (P < 0.05), although no significant change in heart rate (HR) was detected (P = 0.87). Patients with blood group A experienced a significant reduction in HR post-transfusion. …”
Get full text

Importance of appropriate genome information for the design of mating type primers in black and yellow morel populations by Melissa Cravero, Aaron J. Robinson, Patrick Hilpisch, Patrick S. Chain, Saskia Bindschedler, Pilar Junier

“…To evaluate the design and theoretical performance of these primers we performed a thorough bioinformatic investigation, including the detection of the MAT region in publicly available Morchella genomes and in-silico PCR analyses. …”
Get full text

A high fraction of inspired oxygen does not mitigate atelectasis-induced lung tissue hypoxia or injury in experimental acute respiratory distress syndrome by Kentaro Tojo, Takuya Yazawa

“…Another set of animals was used for pimonidazole staining of the lung tissues to detect the hypoxic region. Lung mechanics, ratios of partial pressure of arterial oxygen (PaO2) to FIO2, and partial pressure of arterial carbon dioxide were not significantly different among the three groups, although PaO2 changed with FIO2. …”
Get full text

Assessment of aluminium level in commercial pasteurized and UHT milk in Bangladesh and their potential health risks by Ishrat Jahan, Kazi Md. Al-Noman, Shabbir Ahmed, Mst. Umme Habiba, S. A. Masudul Hoque, Abu Sadeque Md. Selim, Md. Morshedur Rahman

“…The instrumental precision for Al was 0.0212 mg/kg as a limit of detection (LOD) and 0.0643 mg/kg as a limit of quantification (LOQ), with a relative standard deviation (RSD) of 3.2%. …”
Get full text

Anatomical and pathological findings in longlived female Bubalus bubalis by Rosaura Pérez-Gil, Yaritza Salas, Adelys Márquez, Oriana Gavidia

“…Rectal palpation was performed to detect pregnancy. The udder integrity was evaluated, and days open between pregnancies were calculated. …”
Get full text

A system of molecular markers to identify alleles of the Rht-B1 and Rht-D1 genes controlling reduced height in bread wheat by I. V. Porotnikov, O. P. Mitrofanova, O. Yu. Antonova

“…An alternative can be found in the CAPS technology: it detects differences in sequences by digesting PCR products. …”
Get full text

A hypomorphic mutation in the mouse Csn1s1 gene generated by CRISPR/Cas9 pronuclear microinjection by A. V. Smirnov, T. A. Shnaider, A. N. Korablev, A. M. Yunusova, I. A. Serova, N. R. Battulin

“…Most of the mutations represented small deletions (1–10 bp), but we detected several larger deletions as well (100–300 bp). …”
Get full text

Own Experience in the Use of Artificial Intelligence Technologies in the Diagnosis of Esophageal Achalasia by O. A. Storonova, N. I. Kanevskii, A. S. Trukhmanov, V. T. Ivashkin

“…This artificial intelligence programme can be used in clinical practice as a medical decision support tool to optimize the process of differential diagnosis of achalasia and early detection of the disease, to determine the patient's prognosis and to select the method of further treatment.…”
Get full text

Blocking the CD39/CD73 pathway synergizes with anti-CD20 bispecific antibody in nodal B-cell lymphoma by Carsten Müller-Tidow, Peter Dreger, Joseph Kauer, Wolfgang Huber, Clara Kolbe, Berit Brinkmann, Sascha Dietrich, Tobias Roider

“…Existing single-cell data of patient samples examined in this study were used to detect potential biomarkers predicting combination benefits. …”
Get full text

Diagnostic potential of CDK1 and STAT1 in acute kidney injury associated with gastrointestinal cancers: a bioinformatics-based study by Qiuwan Wei, Yiqing Shen, Yiren Tian, Yunzhi Ling

“…ROC curve analysis demonstrated that CDK1 and STAT1 possess high diagnostic value for early detection of AKI in patients with gastrointestinal cancer, with enhanced efficacy when used in combination.ConclusionCDK1 and STAT1 serve as early diagnostic indicators for the occurrence of AKI in gastrointestinal cancer patients.…”
Get full text

A retrospective record-based study to evaluate the profile of TB patients diagnosed and registered at DOTS center at the tertiary care center and to study the gaps in the implement... by Ruchi Arora Sachdeva, Sahil Singh, MK Sen

“…Conclusion: This study thrusts on intensification of strategies like to improve lab infrastructure, to provide CBNAAT and LPA facilities at all medical colleges and district level, and IEC training to doctors (Interns, Medical officers, specialists), TB health workers and laboratory staff with the latest guidelines, importance of updating Nikshay portal and sensitization of treating physicians and lab personnel to send relevant samples for CBNAAT and LPA testing so as to detect drug-resistant cases on time in order to achieve elimination of disease.…”
Get full text

The carcinoid that doesn't select – the role of preoperative echocardiography in carcinoid heart disease by Emese Papp, Mónika Dénes, Anita Zádori, Katalin Takó, Miklós Tóth, Judit Tőke, Jenő Szolnoky, Réka Rácz, Péter Andréka

“…In order to quantify accurately, transesophageal echocardiography (TEE) was performed which confirmed severe MR, and a patent foramen ovale (PFO) was detected. After detailed discussion with the patient, quadruple valve replacement and PFO closure were performed by cardiac surgery. …”
Get full text

Early Effects of Hyperbaric Oxygen on Inducible Nitric Oxide Synthase Activity/Expression in Lymphocytes of Type 1 Diabetes Patients: A Prospective Pilot Study by Ivana Resanovic, Zoran Gluvic, Bozidarka Zaric, Emina Sudar-Milovanovic, Aleksandra Jovanovic, Davorka Milacic, Radmilo Isakovic, Esma R. Isenovic

“…Decreased phosphorylation of ERK1/2 (p<0.05) and Akt (p<0.05) was detected after HBOT. Our results indicate that exposure to HBO decreased iNOS activity/expression via decreasing phosphorylation of ERK1/2 and Akt followed by decreased activity of NFκB.…”
Get full text

Unusual presentation of a patient with partial anomalous pulmonary venous connections without a septal defect: a case report and literature review by Pouya Ebrahimi, Mohammad Hossein Mandegar, Mehrdad Jafari Fesharaki, Negar Ghasemloo, Pedram Ramezani, Tooba Akbari, Fatemeh Naderi

“…However, patients with symptoms such as chest pain, dyspnea, increased pulmonary artery pressure, and right ventricle dilation should undergo surgical treatment to avoid more serious complications, such as heart failure. Key clinical point Detection of PAPVC is not straightforward in many cases and often requires evaluation with various imaging techniques for accurate diagnosis. …”
Get full text

Prevalence and prognosis of malignancy in THSD7A-associated membranous nephropathy: a systematic literature review and clinical case study by Qianqian Xu, Jiayi Li, Yue Yang, Li Zhuo, Hongmei Gao, Shimin Jiang, Wenge Li

“…The prevalence of malignancy in our cohort was 20%. Notably, we detected positive THSD7A staining in both renal and lung cancer tissues in one patient with small cell lung cancer.Conclusions Patients with THSD7A-associated MN should undergo vigilant follow-up assessments, with a particular focus on actively seeking potential tumorigenic lesions to prevent misdiagnosis or oversight.…”
Get full text