Multicentre Harmonisation of a Six-Colour Flow Cytometry Panel for Naïve/Memory T Cell Immunomonitoring by Iole Macchia, Valentina La Sorsa, Irene Ruspantini, Massimo Sanchez, Valentina Tirelli, Maria Carollo, Giorgio Fedele, Pasqualina Leone, Giovanna Schiavoni, Carla Buccione, Paola Rizza, Paola Nisticò, Belinda Palermo, Stefania Morrone, Helena Stabile, Aurelia Rughetti, Marianna Nuti, Ilaria Grazia Zizzari, Cinzia Fionda, Roberta Maggio, Cristina Capuano, Concetta Quintarelli, Matilde Sinibaldi, Chiara Agrati, Rita Casetti, Andrea Rozo Gonzalez, Floriana Iacobone, Angela Gismondi, Filippo Belardelli, Mauro Biffoni, Francesca Urbani

“…The panel was based on a backbone mixture of dried antibodies (anti-CD3, anti-CD4, anti-CD8, anti-CD45RA, and anti-CCR7) to detect naïve/memory T cells, recognised as potential prognostic/predictive immunological biomarkers in cancer immunotherapies. …”
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Targeting the NLRP3 inflammasome abrogates cardiotoxicity of immune checkpoint blockers by Ping Li, Zhen Qin, Yang Lu, Jiamin Gao, Zhenwei Wang, Ge Zhang, Han Yang, Yachen Hou, Dashuai Wang, Pengchong Du, Yunzhe Wang, Quanzhou Chen, Zhaowei Sun, Jinying Zhang, Junnan Tang

“…Bulk and single-cell RNA sequencing was used to detect the changes in cardiac transcriptome and immunological network.Results NLRP3 inhibition reduced inflammatory response and improved cardiac function. …”
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Investigating the Electron-capture Supernova Candidate AT 2019abn with JWST Spectroscopy by Sam Rose, Ryan M. Lau, Jacob E. Jencson, Mansi M. Kasliwal, Kishalay De, Michael E. Ressler, Ori D. Fox, Matthew J. Hankins

“…Similar to the prototypical examples of this class of objects, NGC 300 2008-OT and SN 2008S, AT 2019abn has an extremely red and dusty progenitor detected only in pre-explosion Spitzer/IRAC imaging at 3.6 and 4.5 μ m and not in deep optical or near-infrared Hubble Space Telescope images. …”
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FTO Facilitates Cervical Cancer Malignancy Through Inducing m6A‐Demethylation of PIK3R3 mRNA by Bingxin Chen, Liming Wang, Xiaomin Li, Ci Ren, Chun Gao, Wencheng Ding, Hui Wang

“…After changing the FTO expression level by lentivirus transfection, the proliferation and metastasis ability of cervical cancer cells were detected both in vitro and in vivo. Further, Merip‐seq and Merip‐qPCR are used to profile m6A transcriptome‐wide. …”
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Productivity of coniferous forests evaluated by remote sensing and field-based models by A Kusbach jun, J Krejza, L Homolová, M Fischer, R Janoutová, P Horáček

“…The decreasing trends detected by both approaches indicate deteriorating conditions for NS in lower elevations. …”
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Cross‐ethnicity face anti‐spoofing recognition challenge: A review by Ajian Liu, Xuan Li, Jun Wan, Yanyan Liang, Sergio Escalera, Hugo Jair Escalante, Meysam Madadi, Yi Jin, Zhuoyuan Wu, Xiaogang Yu, Zichang Tan, Qi Yuan, Ruikun Yang, Benjia Zhou, Guodong Guo, Stan Z. Li

“…We organized the Chalearn Face Anti‐spoofing Attack Detection Challenge which consists of single‐modal (e.g. …”
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Community perceptions and determinants of obstetric fistula across gender lines by Wagaye Fentahun Chanie, Aster Berhe, Ambaye Dejen Tilahun, Bikis Liyew, Chernet Baye, Tarekegn Asemaw Akalie, Destaye Shiferaw Alemu, Miteku Andualem Limenih

“…Understanding community attitudes is crucial for prevention, early detection, and support for affected women. A community-based study was conducted from February 1 to April 26, 2024, among 640 women and men to assess attitudes and influencing factors. …”
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BST1047+1156: A (Failing) Ultradiffuse Tidal Dwarf in the Leo I Group by J. Christopher Mihos, Patrick R. Durrell, Aaron E. Watkins, Stacy S. McGaugh, John Feldmeier

“…While our imaging reaches approximately two magnitudes below the tip of the red giant branch at the Leo I distance of 11 Mpc, we find no evidence for an old red giant sequence that would signal an extended star formation history for the object. Instead, we clearly detect the red and blue helium-burning sequences of its stellar populations, as well as the fainter blue main sequence, all indicative of a recent burst of star formation having taken place over the past 50–250 Myr. …”
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Linking The Cancer Imaging Archive and GenBank to the National Clinical Cohort Collaborative by Ahmad Baghal, Joel Saltz, Tahsin Kurc, Prateek Prasanna, Samantha Baghal, Janos Hajagos, Erich Bremer, Shaymaa Al‐Shukri, Joshua L. Kennedy, Michael Rutherford, Tracy Nolan, Kirk Smith, Christopher G. Chute, Fred Prior

“…Abstract Objective This project demonstrates the feasibility of connecting medical imaging data and features, SARS‐CoV‐2 genome variants, with clinical data in the National Clinical Cohort Collaborative (N3C) repository to accelerate integrative research on detection, diagnosis, and treatment of COVID‐19‐related morbidities. …”
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Increased Growth Differentiation Factor 15 Levels Are Associated with HIV-Associated Neurocognitive Impairment: A Pilot Study by Ali Boustani, Mary K. Ford, Jacqueline R. Kulbe, Anna E. Laird, Leeann Shu, Matthew Spencer, Bryant Avalos, Kyle C. Walter, Ronald J. Ellis, Jerel Adam Fields

“…The strong association between GDF15 levels and cognitive impairment severity suggests its potential as a biomarker for the early detection and monitoring of NCI in PWH.…”
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The Wnt/β-Catenin Pathway Regulated Cytokines for Pathological Neuropathic Pain in Chronic Compression of Dorsal Root Ganglion Model by Ye Zhang, Dan Zhao, Xutong Li, Beiyao Gao, Chengcheng Sun, Shaoting Zhou, Yanhong Ma, Xuemei Chen, Dongsheng Xu

“…Our RNA sequencing results showed that several genes related to the Wnt pathway have changed in DRG and spinal cord dorsal horn (SCDH) after CCD surgery. Therefore, we detected the activation of the Wnt/β-catenin pathway in DRG and SCDH and found active β-catenin significantly upregulated in DRG and SCDH 1 day after CCD surgery and peaked on days 7-14. …”
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Peroxisome Proliferator-Activated Receptor Gamma Polymorphisms and Coronary Heart Disease by Jean Dallongeville, Carlos Iribarren, Jean Ferrières, Liisa Lyon, Alun Evans, Alan S. Go, Dominique Arveiler, Stephen P. Fortmann, Pierre Ducimetière, Mark A. Hlatky, Philippe Amouyel, Audrey Southwick, Thomas Quertermous, Aline Meirhaeghe

“…No such association could be detected in ADVANCE. Haplotype distributions were similar in cases and control in both studies. …”
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Rapid diversification of St-genome-sharing species in wheat grasses (Triticeae: Poaceae) accompanied by diversifying selection of chloroplast genes by Li-Na Sha, Ning Chen, Shi-Yong Chen, Yue Zhang, Yi-Ran Cheng, Dan-Dan Wu, Yi Wang, Hou-Yang Kang, Hai-Qin Zhang, Xiao Ma, Yong-Hong Zhou, Xing Fan

“…Analyses of diversification rates detected a significant acceleration approximately five million years ago in the St-genome-sharing taxa. …”
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Spontaneous high clonal expansion of Wilms’ tumor gene 1-specific cytotoxic T-lymphocytes in patients with Wilms’ tumor gene 1-expressing solid tumor by Soyoko Morimoto, Yukie Tanaka, Jun Nakata, Fumihiro Fujiki, Kana Hasegawa, Hiroko Nakajima, Sumiyuki Nishida, Akihiro Tsuboi, Naoki Hosen, Naoki Kagawa, Motohiko Maruno, Akira Myoui, Takayuki Enomoto, Shuichi Izumoto, Mitsugu Sekimoto, Naoya Hashimoto, Toshiki Yoshimine, Atsushi Kumanogoh, Yusuke Oji, Yoshihiro Oka, Haruo Sugiyama

“…Overall, 433 and 351 TCR β-chains of WT1126-CTLs were detected from PTs and HVs, respectively, and complementarity-determining region 3 was sequenced for clonality analysis. …”
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Snake Venom Pharmacokinetics and Acute Toxic Outcomes Following <i>Daboia siamensis</i> Envenoming: Experimental and Clinical Correlations by Sethapong Lertsakulbunlue, Wipapan Khimmaktong, Orawan Khow, Wittawat Chantkran, Jureeporn Noiphrom, Kanyanat Promruangreang, Lawan Chanhome, Janeyuth Chaisakul

“…Intramuscular (i.m.) administration of <i>D. siamensis</i> venom to anesthetized rats (200 µg/kg) resulted in a rapid absorption of venom which reached a peak concentration at 60 min before declining and then plateauing. Urine samples detected 209.3 ± 21.6 ng/mL of <i>D. siamensis</i> venom following i.m. administration at 6 h. …”
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A novel histone acetylation-associated gene signature with prognostic value in Ewing sarcoma by Anshun Wu, Fayin Liu, Lei Zhou, Runyi Jiang, Shangjiang Yu, Zihuan Zhou, Qi Zhang, Qian Zhang, Dongjie Jiang, Shaohui He, Haifeng Wei

“…In conclusion, this is the first study to detect the prognostic values of HARGs in EWS patients, further developing a good prognostic signature based on HARGs, and HDAC2 might be an oncogene in the development of EWS.…”
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Full-length transcriptome analysis of male and female gonads in Japanese Eel (Anguilla japonica) by Jiangling Li, Jingjie Liang, Mengyang Wang, Yuewen Jiang, Wen Li, Mingxi Huang, Yan Huang, Yangjie Xie, Jianchun Chen, Tiansheng Chen

“…Additionally, 1,210 differentially expressed genes were detected. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses revealed significant pathways involved in cell cycle regulation, metabolic processes, apoptosis, and hormone activity. …”
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Aspects of conducting a forensic commodity examination of sunflower oil by L. А. Sоlоnіchenkо, D. Yu. Seredа

“…When conducting an examination of vegetable oils, the following research goals are determined: identification of the type of vegetable oil; methods of falsification and methods of their detection. Assortment falsification in vegetable oils is of the following types: re-grading is widespread, with highly refined vegetable oils being substituted for unrefined and technical oils most often. …”
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American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score: a study protocol for the translation and validation of the Dutch language version by Cornelis H Van der Vlies, Esther M M van Lieshout, Michael H J Verhofstad, Duncan E Meuffels, A Siebe de Boer, Wim E Tuinebreijer, P Ted Den Hoed

“…Descriptive statistics (including floor and ceiling effects), internal consistency, construct validity, reproducibility (ie, test–retest reliability, agreement and smallest detectable change) and responsiveness will be assessed for the AOFAS DLV.Ethics and dissemination This study has been exempted by the Medical Research Ethics Committee (MREC) Erasmus MC (Rotterdam, the Netherlands). …”
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KLRB1 expression in nasopharyngeal mucosa as a prognostic biomarker in COVID-19 patients by Marilina García-Aranda, María Ángeles Onieva, Desirée Martín-García, Raúl Quirós, Inmaculada López, María Padilla-Ruiz, Teresa Téllez, Beatriz Martínez-Gálvez, María Luisa Hortas, Alberto García-Galindo, José González-Gomariz, Rubén Armañanzas, Francisco Rivas-Ruiz, Alfonso Serrano, Isabel Barragán-Mallofret, Maximino Redondo

“…Incorporating KLRB1 into multiplex diagnostic kits alongside SARS-CoV-2 detection could streamline prognostic assessment, providing a more comprehensive and efficient approach to patient management.…”
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