Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System by Fernanda C. Paccola Mesquita, Camila Hochman-Mendez, Jacquelynn Morrissey, Luiz C. Sampaio, Doris A. Taylor

“…Spontaneous differentiation into ectoderm (NESTIN, TUBB3, and NEFH), mesoderm (MSX1, BMP4, and T), and endoderm (GATA6, AFP, and SOX17) lineages was detected by RT-PCR with both coating systems. We conclude that the QES maintains the stemness of iPSCs and is a promising platform to provide the number of cells necessary to recellularize small human-sized organ scaffolds for clinical purposes.…”
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Assessment of renal insufficiency in patients with renal artery stenosis by multiparametric magnetic resonance imaging by Long Zhao, Feng-Bo Xu, Jia-Yi Liu, Shuang Li, Nan Zhang, Zhong-Hua Sun, Guo-Qin Wang, Lei Xu

“…Multiparametric MRI combined with the values of cortical renal blood flow and cortical T1 exhibited the highest diagnostic efficacy, with an AUC of 0.92, and sensitivity of 0.919, and specificity of 0.743.Conclusion Multiparametric magnetic resonance imaging can effectively detect the single renal dysfunction of kidneys with renal artery stenosis, which holds promise for the diagnosis and prognosis of patients with renal artery stenosis.…”
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Demographic and Clinical Presentation of Hospitalised Patients with SARS-CoV-2 During the First Omicron Wave by Mehool Patel, Elizabeth Aitken

“…Methods: Data was obtained over a month in 2021–2022 from multi-ethnic patients who were hospitalised and detected to have severe acute respiratory syndrome coronavirus 2 Omicron infection. …”
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Particle image velocimetry analysis of the protective layer in embankment dams by Nisal Deelaka Halaba Arachchige Senarathna, Théo Dezert, Théo Dezert, Fjóla Guðrún Sigtryggsdóttir

“…Furthermore, this investigation also detected that a graph of the velocity pattern depicting the placed riprap exhibited a higher singular peak while such a graph depicting the dumped riprap exhibited a bimodal characteristic.…”
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M6a demethylase FTO regulates the oxidative stress, mitochondrial biogenesis of cardiomyocytes and PGC-1a stability in myocardial ischemia-reperfusion injury by Qiong Jiang, Xuehai Chen, Kezeng Gong, Zhe Xu, Lianglong Chen, Feilong Zhang

“…The generation of reactive oxygen species (ROS) and the levels of superoxide dismutase (SOD2), mitochondrial transcription factor (TFAM) and cytochrome c oxidase I (COXI) were detected to assess the oxidative stress and mitochondrial biogenesis. …”
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Exploring the perspectives of healthcare workers and Program managers on the use of Truenat as a new tool for TB and DR-TB diagnosis in Nigeria: A qualitative study. by Nkiru Nwokoye, Austin Ihesie, Jamiu Olabamiji, Kingsley Ochei, Rupert Eneogu, Michael Umoren, Femi Odola, Debby Nongo, Aderonke Agbaje, Bethrand Odume, Omosalewa Oyelaran, Wayne van Germert, Lucy Mupfumi, Elom Emeka, Chukwuma Anyaike, Sarah Cook Scalise, Edmund Ndudi Ossai

“…<h4>Background</h4>World Health Organization in the year 2020 recommended the use of Truenat as a replacement for smear microscopy in Tuberculosis (TB) diagnosis and detection of rifampicin resistance. This study was designed to assess enablers and barriers to effective implementation of Truenat assays for TB diagnosis in Nigeria and determine the acceptability of use of Truenat among healthcare workers and TB Program managers in Nigeria.…”
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Pituitary Stalk Interruption Syndrome: A Case and Literature Review by Anuja Choure, MD, Leena Shahla, MD

“…Diagnosis is confirmed by a dedicated pituitary magnetic resonance imaging, and treatment is tailored to the hormonal deficiency detected. Conclusion: This case highlights the importance of early diagnosis of PSIS, which presents with multiple anterior pituitary hormonal deficiencies, but diagnosis can remain elusive unless dedicated brain imaging is performed.…”
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Rootstocks for Florida Stone Fruit by Ali Sarkhosh, Mercy Olmstead, Jose Chaparro, Thomas Beckman

“…However, in 1966 a new species of root-knot nematode was detected on ‘Nemaguard’ and ‘Okinawa’ peach rootstocks in Gainesville, Florida, and ultimately identified as M. floridensis in 2004 (Han-doo, et al., 2004). …”
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Temperature measurements with a temporal scanner: systematic review and meta-analysis by Ruzan Udumyan, Håkan Geijer, Georg Lohse, Ylva Nilsagård

“…A secondary outcome was sensitivity and specificity to detect fever. If tympanic thermometers were assessed in the same population as TAT, these results were recorded as well.Results 37 articles comprising 5026 participants were selected. …”
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Sm10.3, a member of the micro-exon gene 4 (MEG-4) family, induces erythrocyte agglutination in vitro and partially protects vaccinated mice against Schistosoma mansoni infection. by Vicente P Martins, Suellen B Morais, Carina S Pinheiro, Natan R G Assis, Barbara C P Figueiredo, Natasha D Ricci, Juliana Alves-Silva, Marcelo V Caliari, Sergio C Oliveira

“…Immunization of mice with rSm10.3 induced a mixed Th1/Th2-type response, as IFN-γ, TNF-α, and low levels of IL-5 were detected in the supernatant of cultured splenocytes. …”
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A laboratory feasibility study using a computer algorithm for anastomosis segmentation of epicardial ultrasonography images from distal coronary artery bypass anastomoses by Alex Skovsbo Jørgensen, Martin Siemienski Andersen, Lasse Riis Østergaard, Samuel Emil Schmidt, Dorte Nøhr, Jan Jesper Andreasen

“…., technical suture failures, and such failures may be detected using intraoperative quality assessment. High-intensity epicardial ultrasonography (ECUS) allows anatomical visualization of the anastomoses during surgery, but currently, the images must be assessed manually. …”
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The Clinical Importance of Optic Nerve Sheath Diameter in Patients with Traumatic Brain Injury: Preliminary Report by Burcu AVCI OZBALIK, Tugba BINGOL TANRIVERDI, Hafize Gulsah OZCAN, Melek GURA CELIK

“…Conclusions: The enlargement of ONSD on initial CT was detected to be associated with increased in-hospital mortality in patients with severe TBI.…”
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The genomes of Scedosporium between environmental challenges and opportunism by Francesco Venice, Federica Spina, Domenico Davolos, Stefano Ghignone, Giovanna Cristina Varese

“…By contrast, several features in Microascaceae and Scedosporium were detected that might have a dual role in responding to environmental challenges and allowing colonization of the human body, including chitin, melanin and other cell wall related genes, proteases, glutaredoxins and magnesium transporters. …”
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Symbiotic diversity of Portunus pelagicus (Linnaeus, 1758) in Vietnam - implication for species and geographic variations by Binh Thuy Dang, Oanh Thi Kieu Le, Sang Quang Tran, Oanh Thi Truong

“…Combined host features (distribution, sex and size) against symbiont diversity were also detected to be significantly different. Considering the host-symbiont associations, diversity indexes did not show a clear connection between host features and symbiotic diversity. …”
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Serum hydroxycotinine was associated with chronic kidney disease (CKD): a cross-sectional study based on NHANES by Meng’en Zhu, Zhimin Bi, Yaoling Wang, Wei Li

“…Serum hydroxycotinine was measured by an isotope-dilution high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometric (ID HPLC-APCI MS/MS) method with a lower limit of detections (LLOD) at 0.015 ng/mL. The non-linear relationship was explored with restricted cubic splines (RCS). …”
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MicroRNAs obtained from cervical swabs in predicting preterm birth by Rosalia Purbandari, Suheni Ninik Hariyati

“…This systematic review examines current research on the effectiveness of cervical swab miRNAs in predicting and estimating preterm birth risks, aiming to enhance early detection and management strategies for preterm births. …”
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Radioisotope and Metal Concentrations in Borehole Water Samples of Umuahia and Umudike, Nigeria by J.C. Nnaji, O.U. Igwe, K.M. Onyedim, P. Okafor

“…The mean activity concentrations K-40, U-238 and Th-232 had ranges of below detection limit (BDL) – 21.94±2.50 Bq/L; BDL – 7.85 ±1.80 Bq/L and BDL – 5.76 ±0.53 respectively. …”
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Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning by Shuxian Pan, Zibing Wang

“…However, Immunotherapy-related adverse reactions are still a major challenge faced by tumor immunotherapy, so it is urgent to establish new methods to effectively predict immunotherapy-related adverse reactions.ObjectiveMulti-machine learning model were constructed to screen the risk factors for irAEs in ICIs for the treatment of HBV-related hepatocellular and build a prediction model for the occurrence of clinical IRAEs.MethodsData from 274 hepatitis B virus positive tumor patients who received PD-1 or/and CTLA4 inhibitor treatment and had immune cell detection results were collected from Henan Cancer Hospital for retrospective analysis. …”
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Concordant Signal of Genetic Variation Across Marker Densities in the Desert Annual Chylismia brevipes Is Linked With Timing of Winter Precipitation by Daniel F. Shryock, Nila Lê, Lesley A. DeFalco, Todd C. Esque

“…Ancestry analyses indicated consistent spatial genetic structuring into four regional populations. We also detected a marked signal of isolation by resistance (IBR), wherein spatial genetic structure was better explained by habitat resistance than by geographic distance. …”
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Incidence and Anatomical Properties of Retromolar Canal in an Iranian Population: A Cone-Beam Computed Tomography Study by N. Nikkerdar, A. Golshah, M. Norouzi, S. Falah-Kooshki

“…Two major types of canals were detected, namely, type I, following a straight or curved course from the mandibular canal (MC) to the retromolar area (47.3%), and type II, coursing from the retromolar area to the radicular part of the third molar (52.7%). …”
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