Identification of Plasma Proteins Associated with Alzheimer's Disease Using Feature Selection Techniques and Machine Learning Algorithms by Zakaria Mokadem, Mohamed Djerioui, Bilal Attallah, Youcef Brik

“… Alzheimer’s disease (AD) is a chronic, progressive neurodegenerative disorder that typically affects elderly individuals. Detecting Alzheimer’s using plasma proteins is a critical step toward improving treatment results for this disease. …”
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Targeting mutant p53: Evaluation of novel anti-p53R175H monoclonal antibodies as diagnostic tools by Diana Spiegelberg, Le-Ann Hwang, Khian Hong Pua, Sashwini Chandra Kumar, Xin Yu Koh, Xiao Hui Koh, Ram Kumar Selvaraju, Kanaga Sabapathy, Marika Nestor, David Lane

“…Significantly higher uptake was detected in the mut-p53-expressing tumors, confirmed by ex vivo autoradiography. …”
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Very High Energy Solar Energetic Particle Events and Ground Level Enhancement Events: Forecasting and Alerts by N. Crosby, H. Mavromichalaki, O. Malandraki, M. Gerontidou, M. Karavolos, D. Lingri, P. Makrantoni, M. Papailiou, P. Paschalis, A. Tezari

“…For such events to be detected at sea level, proton energies must exceed about 433 MeV. …”
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Genomic characteristics of a Streptococcus suis of ST353 resulting in severe endophthalmitis with bilateral deafness by Liang Shen, Yanfei Tong, Shichao Li, Yuda Chen, Ruhan A, Zhen Li, Wenling Wang, Lijuan Yin, Jiuming Zou, Ziyong Sun, Changcheng Wu, Wenjie Tan, Haijuan Wang

“…The diagnosis was made on the basis of clinical symptoms, imaging, molecular detection, and isolated culture methods. Drug susceptibility testing was conducted to determine the effectiveness of antibiotics. …”
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Hydrogen Leakage Location Prediction in a Fuel Cell System of Skid-Mounted Hydrogen Refueling Stations by Leiqi Zhang, Qiliang Wu, Min Liu, Hao Chen, Dianji Wang, Xuefang Li, Qingxin Ba

“…This approach addresses the limitations of sensor detection in accurately locating leaks and mitigates the risks associated with manual inspections. …”
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Femoral Head Pathology in Subcapital Hip Fractures: Clinical Value and Cost-Effectiveness in a 230-Patient Case Series by Nissim Ohana, Omer Marom, David Segal, Refael Behrbalk, Yuval Ben-Sira, Alex Tavdi, Ezequiel Palmanovich, Eyal Yaacobi

“…The most common malignancies detected were breast cancer and multiple myeloma (three cases each). …”
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Expression of LAIR-1 (CD305) on Human Blood Monocytes as a Marker of Hepatic Cirrhosis Progression by María Martínez-Esparza, Antonio José Ruiz-Alcaraz, Violeta Carmona-Martínez, María Dolores Fernández-Fernández, Gonzalo Antón, María Muñoz-Tornero, Miriam Lencina, Inmaculada Pagán, Jesús de la Peña, Pilar García-Peñarrubia

“…These results may indicate that monocyte LAIR-1 expression is a new biomarker to early detect liver damage caused by chronic inflammation in liver cirrhosis.…”
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Autophagy-Enhancing Properties of <i>Hedyotis diffusa</i> Extracts in HaCaT Keratinocytes: Potential as an Anti-Photoaging Cosmetic Ingredient by Qiwen Zheng, Xiangji Jin, Trang Thi Minh Nguyen, Eun-Ji Yi, Se-Jig Park, Gyeong-Seon Yi, Su-Jin Yang, Tae-Hoo Yi

“…This study investigates HD’s potential to counteract skin photoaging by restoring mitochondrial autophagy in keratinocytes. We used HPLC to detect the main chemical components in HD and, using a UVB-induced photoaging model in HaCaT keratinocytes, examined the effects of HD on reactive oxygen species (ROS) levels, Ca²⁺ concentration, mitochondrial membrane potential (MMP), apoptosis, and the cell cycle. …”
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MetALD: Clinical aspects, pathophysiology and treatmentKeypoints by Jordi Gratacós-Ginès, Silvia Ariño, Pau Sancho-Bru, Ramon Bataller, Elisa Pose

“…In this review article, we examine the clinical evidence and the experimental models of MetALD and discuss the clinical implications of the term for early detection and management. We provide insight into the pathophysiological mechanisms of the synergistic effect of alcohol and metabolic risk factors, possible screening strategies, the use of biomarkers and emerging models of care, as well as potential therapeutic interventions with a special focus on medications for MASLD, highlighting the most promising drugs for patients with MetALD.…”
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Development and Evaluation of a Hydrometeorological Forecasting System Using the Coupled Ocean-Atmosphere-Wave-Sediment Transport (COAWST) Model by Jing Zou, Chesheng Zhan, Haiqing Song, Tong Hu, Zhijin Qiu, Bo Wang, Zhiqian Li

“…Resulting from that, a forecasted bias of lower surface pressure, higher air humidity, stronger south wind, and so forth was also detected over the domain but at low values.…”
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Ascaris lumbricoides a rare cause gastric perforation: a case report and brief literature review by Tian-Hao Xie, Tian-Hao Xie, Yan Fu, Xiang-Xiang Ren, Xin-Li Sun, Qiang Wang, Qian Sun

“…Additionally, fecal tests conducted over three consecutive days did not detect any AL eggs. This case highlights the crucial importance of recognizing ascariasis-associated complications and underscores the paramount role of timely surgical intervention in such cases. …”
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Isolation, genetic, and biological characterization of human adenovirus type 55 positive isolates from Wuhan, China by Jing Xie, Yan Wang, Huan Li, Bingxiu Tan, Zhengying Yu, Lizhong Li, Wei Zhang, Hongbin Song, Leili Jia

“…Although the hamsters and mice were not so susceptible to HAdV-55-174 infection, viral loads were detected in the lungs and tracheas of the animal models, and persistent HAdV-55-174 replication was only observed in BALB/c nude mice. …”
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Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs by Sishu Guan, Zhikang Liao, Hongyi Xiang, Xiyan Zhu, Zhong Wang, Hui Zhao, Peng Liu, Xinan Lai

“…The injuries of the spleen, lung, heart, and spine were detected frequently among the tested subjects. The maximal AIS (MAIS) of chest injuries was 4 in group I and 5 in group II, while both the MAIS of abdomen injuries in group I and group II were 5. …”
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Prevalence of Japanese encephalitis in pigs in Mainland China during 2000–2024: a systemic review and meta-analysis by Xue-Tong Liu, Li-Dong Jiang, Yu-Ting Lin, Ran Zhao, Qi Wang, Shu-Ying Zhang, Shu-Ying Zhang, Shu-Ying Zhang, Emad Beshir Ata, Xin Liu, Yuan Wang, Zi-Xuan Liu, Cui Xu, Ying Xiao, Yi-Fan Wang, Xue Leng, Qing-Long Gong, Rui Du, Rui Du, Rui Du

“…Serum samples showed the highest prevalence 38.1% (95% CI: 27.9–48.9), and ELISA testing had a higher detection rate 38.2% (95% CI: 24.5–52.9). In the farming mode subgroup, the highest prevalence was observed in the large-scale farming mode at 40.9% (95% CI: 26.4–66.3).ConclusionThe study highlights the spread of JE across China and suggests that it may be underrecognized in some areas. …”
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Multimodal fusion model for diagnosing mild cognitive impairment in unilateral middle cerebral artery steno-occlusive disease by Ziyi Yuan, Zhaodi Huang, Chaojun Li, Shengrong Li, Qingguo Ren, Xiaona Xia, Qingjun Jiang, Daoqiang Zhang, Qi Zhu, Xiangshui Meng, Xiangshui Meng

“…Efficient automated diagnosis facilitates the early and accurate detection of MCI and timely intervention and treatment to delay or prevent disease progression.…”
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Harmful impacts of microplastic pollution on poultry and biodegradation techniques using microorganisms for consumer health protection: A review by Mohamed E. Abd El-Hack, Elwy A. Ashour, Fatemah AlMalki, Asmaa F. Khafaga, Mahmoud Moustafa, Mohammed O. Alshaharni, Islam M. Youssef, Ahmed A. Elolimy, Sylwester Świątkiewicz

“…Microplastics have been detected in various animal species, including poultry, fish, mammals, and invertebrates, indicating widespread exposure and potential bioaccumulation. …”
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Differentiation of Rat Adipose-Derived Stem Cells into Parathyroid-Like Cells by Ping Zhang, Hao Zhang, Wenwu Dong, Zhihong Wang, Yuan Qin, Changhao Wu, Qi Dong

“…The differentiation of the adipose-derived stem cells to parathyroid-like cells was confirmed by the detection of parathyroid hormone and the related parathyroid markers. …”
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Clinical predictive model of new-onset atrial fibrillation in patients with acute myocardial infarction after percutaneous coronary intervention by Xiao-Dan Wu, Wei Zhao, Quan-Wei Wang, Xin-Yu Yang, Jing-Yue Wang, Shuo Yan, Qian Tong

“…By incorporating the TyG index into the predictive model, NOAF after AMI during hospitalization can be effectively predicted. Early detection of NOAF can significantly improve the prognosis of AMI patients.…”
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Comparing Campylobacter jejuni to three other enteric pathogens in OligoMM12 mice reveals pathogen-specific host and microbiota responses by Mathias K.-M. Herzog, Audrey Peters, Nizar Shayya, Monica Cazzaniga, Kardokh Kaka Bra, Trisha Arora, Manja Barthel, Ersin Gül, Luca Maurer, Patrick Kiefer, Philipp Christen, Katharina Endhardt, Julia A. Vorholt, Gad Frankel, Markus M. Heimesaat, Stefan Bereswill, Cormac G. M. Gahan, Marcus J. Claesson, Xavier Domingo-Almenara, Wolf-Dietrich Hardt

“…Additionally, our comparative approach successfully identifies pathogen-specific responses, including the detection of genes uniquely associated with C. jejuni infection in humans. …”
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TCR transgenic clone selection guided by immune receptor analysis and single-cell RNA expression of polyclonal responders by Nincy Debeuf, Sahine Lameire, Manon Vanheerswynghels, Julie Deckers, Caroline De Wolf, Wendy Toussaint, Rein Verbeke, Kevin Verstaen, Hamida Hammad, Stijn Vanhee, Bart N Lambrecht

“…Since the precursor frequency of naive T cells is extremely low, investigating the early steps of antigen-specific T cell activation is challenging. To overcome this detection problem, adoptive transfer of a cohort of T cells purified from T cell receptor (TCR) transgenic donors has been extensively used but is not readily available for emerging pathogens. …”
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