Development of a respiratory virus risk model with environmental data based on interpretable machine learning methods by Shuting Shi, Haowen Lin, Leiming Jiang, Zhiqi Zeng, ChuiXu Lin, Pei Li, Yinghua Li, Zifeng Yang

“…The data was collected from 31 regions in China between 2016 and 2021, encompassing pathogen detection, air quality indices, and meteorological measurements. …”
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METTL3-dependent DLG2 inhibits the malignant progression of cervical cancer by inactivating the Hippo/YAP signaling by Mei Pu, Xia Xiao, Shasha Lv, Daqing Ran, Qian Huang, Mingming Zhou, Qirong Lei, Lingshuang Kong, Qing Zhang

“…Methods Quantitative reverse transcription polymerase chain reaction and western blotting assays were employed to detect RNA and protein expression, respectively. Colony formation assay, 5-Ethynyl-2’-deoxyuridine assay, flow cytometry, and transwell assays were conducted for cell functional analysis. …”
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Identification of Target Genes of Antiarrhythmic Traditional Chinese Medicine Wenxin Keli by Yusi Yao, Yuhong Liu, Zhihuan Zeng, Yanqun Zhao, Tudi Li, Rong Chen, Rendan Zhang

“…MI, QT interval, heart rate, and arrhythmia were recorded, and the mRNA expression of target genes in myocardial tissues was detected by PCR. Eleven active ingredients of WXKL and eight WXKL-targeting arrhythmia-related genes were screened. …”
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Spatio-temporal Distribution of Aboveground Forest Biomass and Carbon in Tropical Dry Forest under Anthropogenic Pressure, Brazil by Gabriela Salami, Rinaldo Luiz Caraciolo Ferreira, José Antônio Aleixo da Silva, Fernando José Freire, Emanuel Araújo Silva, Marco Antonio Diodato, Dhonatan Diego Pessi

“…This investigation seeks to elucidate these dynamics and provide insights for management and conservation strategies based on robust empirical data, in addition to answering the following questions: Does the history of anthropogenic interventions in Dry Tropical Forest areas cause variations in the spatial distribution of biomass and carbon stocks that can be detected by the kriging method? Which attributes related to conservation and anthropogenic use reflect the spatial distribution of biomass and carbon stocks in Dry Tropical Forest areas? …”
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The Role of Gut Microbiota in Male Erectile Dysfunction of Rats by Zhunan Xu, Shangren Wang, Chunxiang Liu, Jiaqi Kang, Yang Pan, Zhexin Zhang, Hang Zhou, Mingming Xu, Xia Li, Haoyu Wang, Shuai Niu, Li Liu, Daqing Sun, Xiaoqiang Liu

“…After 24 weeks, erectile function of the rats was evaluated and 16S rRNA sequencing was performed, and serum samples were collected for the untargeted metabolomics detection. Results: The erectile function of rats and the species diversity of intestinal microbiota in the HFD group was significantly lower, and the characteristics of the intestinal microbiota community structure were also significantly different between the two groups. …”

Characterization of Cantal and Salers Protected Designation of Origin Cheeses Based on Sensory Analysis, Physicochemical Characteristics and Volatile Compounds by Cécile Bord, Louis Lenoir, Julie Benoit, Delphine Guérinon, Gilles Dechambre, Christophe Chassard, Christian Coelho

“…A large number of volatile compounds (VOCs) belonging to acids, alcohols, aldehydes, ketones and esters were detected in each cheese category (<i>n</i> = 78). The relative quantity of each compound varied depending on the cheese category but was lowly impacted by the origin of the breed’s milk. …”
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The Sanya Incoherent Scatter Radar Tristatic System and Initial Experiments by Xinan Yue, Baiqi Ning, Lin Jin, Feng Ding, Changhai Ke, Junyi Wang, Ning Zhang, Yihui Cai, Mingyuan Li, Junhao Luo, Weiping Chen, Yunxia Zhang, Biqiang Zhao, Lingqi Zeng, Yonghui Wang

“…Initial collaborative satellite tracking and ionospheric common volume experiments among three stations have confirmed the detection ability of SYISR‐TS and the feasibility of achieving its scientific goals in the future.…”
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Multi-Criteria Assessment of Urban Thermal Hotspots: A GIS-Based Remote Sensing Approach in a Mediterranean Climate City by Javier Sola-Caraballo, Antonio Serrano-Jiménez, Carlos Rivera-Gomez, Carmen Galan-Marin

“…Within GIS workflow, the city is divided into LCZs, thermal hotspots are detected, and finally, it is analyzed to understand how urban factors, such as urban boundaries, building density, and vegetation, affect urban scale LST, all using graphical and analytical cross-assessment. …”
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Insights into Treponema pallidum genomics from modern and ancient genomes using a novel mapping strategy by Marta Pla-Díaz, Gülfirde Akgül, Martyna Molak, Louis du Plessis, Hanna Panagiotopoulou, Karolina Doan, Wiesław Bogdanowicz, Paweł Dąbrowski, Maciej Oziembłowski, Barbara Kwiatkowska, Jacek Szczurowski, Joanna Grzelak, Natasha Arora, Kerttu Majander, Fernando González-Candelas, Verena J. Schuenemann

“…Our findings show that recombination detection was consistent across different references, but the choice of reference significantly affected ancient genome reconstruction and phylogenetic inferences. …”
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Immersive virtual reality to assess unilateral spatial neglect in stroke patients: a preliminary study by Chloé Sauvage, Pierre Chaulet, Luana Rivas Lopez, Johanne Garbusinski, Pierre Cabaraux, Zachary Duvigneaud, Stéphane Baudry

“…Objectives: The conventional test to detect unilateral spatial neglect (USN) is the Bells Test performed in a paper-and-pencil format. …”
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Reusable Tourniquets as Potential Transmitters of Infection: A Microbiological Analysis by Julia Szymczyk, Monika Kurpas, Bartosz Krasiński, Katarzyna Zorena, Wioletta Mędrzycka-Dąbrowska

“…Results: Significant bacterial loads were detected on reusable tourniquets, with contamination levels varying by location and duration of use. …”
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The Development of the Radial Bow in Children: Normative Values by Samara F. Kass, Julia L. Conroy, Alisa Forsberg, Rebecca S. Li, Catherine C. May, Natasha S. McKibben, Julio J. Jauregui, Raymond W. Lui, Joshua M. Abzug

“…Furthermore, they can aid in the detection of subtle fractures of the radius, including plastic deformations and greenstick fractures.…”
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Treatment of chronic hepatitis B: options, monitoring, special cases and adverse effects by Mateusz Litwin Litwin, Agnieszka Mikosińska, Jakub Parys, Patrycja Kałuziak, Aleksandra Witek, Martyna Kaźmierczak, Stanisław Jesionek, Marta Jajczak, Maciej Mossakowski

“…Even in Europe, where vaccination coverage has reached high levels, cases of hepatitis B are still detected, often incidentally. This review aims to provide an in-depth analysis of therapeutic approaches for chronic hepatitis B, considering factors such as patient age, clinical status, and liver fibrosis stage. …”
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Lifetime Attributable Risk in Mammography Screenings in Dubai: The Influence of Breast Thickness and Age on Radiation Exposure by Kaltham Abdulwahid Mohd Noor, Norhashimah Mohd Norsuddin, Iza Nurzawani Che Isa, Muhammad Khalis Abdul Karim

“…<b>Conclusions:</b> Personalized screening protocols considering age and breast thickness are crucial for balancing early cancer detection benefits with radiation risks. Future research should improve mammography protocols, explore alternative methods, and consider generic testing for young high-risk patients to mitigate risks while maintaining diagnostic efficacy.…”
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Efflux Pump Activity and Mutations Driving Multidrug Resistance in Acinetobacter baumannii at a Tertiary Hospital in Pretoria, South Africa by Noel-David Nogbou, Granny M. Nkawane, Khanyisa Ntshane, Charles K. Wairuri, Dikwata T. Phofa, Kagiso K. Mokgokong, Mbudzeni Ramashia, Maphoshane Nchabeleng, Lawrence C. Obi, Andrew M. Musyoki

“…Efflux pump was found in 75% of isolates as a mechanism of resistance. The study detected parC gene mutation in 60% and gyrA gene mutation in 85%, while 37% of isolates had mutations on both genes. …”
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Quercetin inhibits truncated isoform of dopamine- and cAMP-regulated phosphoprotein as adjuvant treatment for trastuzumab therapy resistance in HER2-positive breast cancer by Han-Sheng Chang, Tzu-Chun Cheng, Shih-Hsin Tu, Chih-Hsiung Wu, You-Cheng Liao, Jungshan Chang, Min-Hsiung Pan, Li-Ching Chen, Yuan-Soon Ho

“…We established 2 patient-derived xenografts (PDX) mice models to test the efficacy of trastuzumab, named model 1 (non-responder) and model 2 (responder). t-DARPP and p95-HER2 protein-protein interactions were detected in PDX tumor tissue from non-responders using Förster resonance energy transfer assays. …”
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The mechanism of endoplasmic reticulum (ER) stress in cell apoptosis and ROS (reactive oxygen species) of CNE2 cell line induced by single wall carbon nanohorn (SWCNH) by Xianbao Cao, Shunmin Gong, Shujin Chen, Shuang Hu, Tianshu Li, Yanfei Guan, Chun Feng, Jinqian Zhang

“…Moreover, the apoptotic protein expression of caspase 3 (cysteinyl aspartate specific proteinase 3), the expression levels of ER pathway protein eIF2α, ATF4 and CHOP, or the OS (Oxidative stress)-related proteins NQO1, GCLC, HO-1, and Nrf2 was detected, respectively.ResultsCNE2 apoptotic rate, ROS levels, the caspase 3 or ER pathway proteins ATF4 and CHOP expression, even the NQO1, GCLC, HO-1, and Nrf2 levels of oxidative stress-related proteins in the groups of SWCNH and SWCNH+4-PBA were higher compared to the control group. …”
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Phenolic Contents and Antioxidant Activity of Extracts of Selected Fresh and Dried Herbal Materials by Mariola Kozłowska, Iwona Ścibisz, Jarosław Przybył, Małgorzata Ziarno, Anna Żbikowska, Ewa Majewska

“…The highest TPC (146.77 g GAE/kg extract) and antioxidant activity (0.491, 0.643, and 0.396 mol TE/kg extract in DPPH, ABTS, and FRAP assays, respectively) were detected for the extract from dried leaves of Indian borage, while the lowest values were determined for the extract from fresh aerial parts of coriander. …”
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Structure and Expression Analyses of SVA Elements in Relation to Functional Genes by Yun-Jeong Kwon, Yuri Choi, Jungwoo Eo, Yu-Na Noh, Jeong-An Gim, Yi-Deun Jung, Ja-Rang Lee, Heui-Soo Kim

“…In an analysis of genomic structure, SVA elements are detected in the 5' untranslated region (UTR) of HGSNAT (SVA-B), MRGPRX3 (SVA-D), HYAL1 (SVA-F), TCHH (SVA-F), and ATXN2L (SVA-F) genes, while some elements are observed in the 3'UTR of SPICE1 (SVA-B), TDRKH (SVA-C), GOSR1 (SVA-D), BBS5 (SVA-D), NEK5 (SVA-D), ABHD2 (SVA-F), C1QTNF7 (SVA-F), ORC6L (SVA-F), TMEM69 (SVA-F), and CCDC137 (SVA-F) genes. …”
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Fragment optimized chalcone derivatives targeting OmpA protein as a therapeutic approach against multidrug resistant Acinetobacter baumannii by Muhammad Naveed, Amina Abid, Tariq Aziz, Ayesha Saleem, Arooj Arshad, Khushbakht Javed, Hafiz Muzzammel Rehman, Ghulam Nabi, Mitub Al-harbi, Abdullah F. Alasmari

“…ADMET and toxicity analysis was performed of both the compounds isobavachalcone and FOI which revealed favorable pharmacokinetic profiles for both compounds, but toxicity analysis showed discrepancies, with the isobavachalcone exhibiting toxicity but FOI compound showing no detectable toxicity. This underscores the importance of structure optimization in drug development. …”
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