Causal associations between socioeconomic status and prostate cancer using two-sample Mendelian randomization study by Zhenxing Wang, Chunyan Wang, Xing Gou, Liang Pei, Xiaoyuan Qiao

“…We employed the inverse variance weighted (IVW), weighted median, weighted mode and MR-Egger to estimate the causal effect, with sensitivity analyses such as Cochran’s Q tests, MR-Egger, MR-PRESSO and leave-one-out performed to detect potential heterogeneity and pleiotropy. Our MR analysis revealed a causal association between unemployment and prostate cancer (OR: 3.07, 95%CI:1.12–8.42, P = 0.03). …”
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Characterization of terpenoids and norisoprenoids from base and retail Qingke Baijiu by GC × GC-TOFMS and multivariate statistical analysis by Xinlei Wang, Lin Zhu, Xuebo Song, Si Jing, Fuping Zheng, Mingquan Huang, Shengbao Feng, Luzhong La

“…The results showed that γ-terpinene (0.70–530.72 μg/L), α-phellandrene (0.34–256.66 μg/L), longicyclene (0–38.55 μg/L), α-pinene (1.21–35.54 μg/L) and limonene (0.93–23.69 μg/L) were the top 5 terpenoids/norisoprenoids in Qingke Baijiu. Pulegone was detected and reported for the first time in Baijiu, and the concentrations in Qingke Baijiu were 0.78 μg/L (fresh) and 3.90 μg/L (7 years old). …”
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Critical assessment of uncertainty in economic evaluations on influenza vaccines for the elderly population in Spain by Raúl Ortiz-de-Lejarazu Leonardo, Javier Díez Domingo, Ángel Gil de Miguel, Federico Martinón Torres, Esther Redondo Margüello, Juan Luis López-Belmonte Claver, Paloma I. Palomo-Jiménez, J. Manel Farré Avellà, José María Abellán Perpiñán

“…Overall, they were designed and performed in accordance with the applicable guidelines; however, some critical sources of uncertainty were detected, mainly: (1) the choice and use of efficacy/effectiveness data (real-world single season studies, meta-analyses including studies with high risk of bias and/or high heterogeneity with biased interpretation); (2) use of fewer than 5 seasons to estimate influenza burden; (3) generalized use of influenza-like illness data to estimate effectiveness and burden, among others. …”
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Fipronil prevents transmission of Lyme disease spirochetes by Radek Šíma, Adéla Palusová, Tereza Hatalová, Luise Robbertse, Petra Berková, Martin Moos, Petr Kopáček, Veronika Urbanová, Jan Perner, Ala Tabor

“…No spirochetes were detected in any organ of mice exposed to fipronil-treated ticks, while 9 out of 10 control mice, exposed to non-treated infectious ticks, displayed Borrelia infection. …”
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Radial Evolution of Interplanetary Shock Properties with Heliospheric Distance: Observations from Parker Solar Probe by Oksana Kruparova, Adam Szabo, Lan K. Jian, František Němec, Jana Šafránková, Zdeněk Němeček, Jacob Pasanen, Ayris Narock, Vratislav Krupar

“…Utilizing our ShOck Detection Algorithm database, the shocks are categorized into fast-forward, fast-reverse, slow-forward, and slow-reverse types. …”
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Dynamic analysis of growth characteristics, secondary metabolites accumulation, and an in-depth understanding of anthraquinones biosynthesis in Rubia cordifolia Linn. by Conglong Lian, Conglong Lian, Conglong Lian, Xiuyu Liu, Xiuyu Liu, Kaihua Guo, Kaihua Guo, Hao Yang, Hao Yang, Jingfan Yang, Jingfan Yang, Jinxu Lan, Jinxu Lan, Suiqing Chen, Suiqing Chen, Suiqing Chen, Suiqing Chen

“…In addition, RT-qPCR was used to detect the relative expression levels of 12 candidate ungenes in the above- and underground parts of R. cordifolia. …”
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Corticosterone-induced postpartum depression induces depression-like behavior and impairs hippocampal neurogenesis in adolescent offspring via HPA axis and BDNF-mTOR pathway by Hongxiao Xie, Yanning Jiang, Xiumeng Zhang, Xinran Min, Jiuseng Zeng, Li Chen, Nan Zeng, Rong Liu

“…These offspring also showed diminished levels of DCX+, decreased levels of synaptic proteins, and reduced dendritic spine density and length in hippocampus. Additionally, we detected increased serum stressed hormones and decreased hippocampal glucocorticoid receptor (GR) protein level in the offspring. …”
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Open resection and reconstruction of a Nasoseptal Chondrosarcoma: case report and literature review by Changseok Lee, David Forner, Martin Bullock, Matthew H. Rigby, Martin Corsten, Jonathan R. Trites, S. Mark Taylor

“…Abstract Background Primary chondrosarcomas of the nasal septum are rare, with a variety of clinical features that evade detection and treatment. While endoscopic surgery has become increasingly accessible, open approaches may be needed to provide adequate visualization for tumour ablation and reconstruction. …”
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Psychometric properties of the Insomnia Severity Index (ISI) in Mexican adults by Horacio Balam Álvarez García, Isaías Vicente Lugo-González, Fabiola González Betanzos

“…Due to this, it is important to have brief, reliable and valid psychometric instruments that allow health personnel their timely detection in first level health centers. Objectives: Analyze the psychometric properties of the Insomnia Severity Index (ISI) in its version adapted to Spanish in a sample of Mexican adults. …”
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Experience with the use of glucocorticosteroid implants in patients with macular edema associated with sarcoidosis. by V.A. Pavlov, E.V. Kryukov, D.V. Davydov, A.A. Zaytsev, V.E. Kurnosov

“…During the observed period in both groups, no complications were detected in any case. According to visometry and OCT, the best functional results were obtained in group 1. …”
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De novo assembly and analysis of the transcriptome of the Siberian wood frog Rana amurensis by D. N. Smirnov, S. V. Shekhovtsov, A. A. Shipova, G. R. Gazizova, E. I. Shagimardanova, N. A. Bulakhova, E. N. Meshcheryakova, T. V. Poluboyarova, E. E. Khrameeva, S. E. Peltek, D. I. Berman

“…In the transcriptome assembled from about 100,000,000 reads, 81.5 % of transcripts were annotated as complete, 5.3 % as fragmented, and 13.2 % as missing. We detected 59,078 known transcripts that clustered into 22,251 genes; 11,482 of them were assigned to specific GO categories. …”
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Vaccine Prophylaxis of Pneumococcal Infections in Children under Conditions of Severe Flood in the Amur River Basin by Aleksandr G. Chuchalin, Gennadiy G. Onishchenko, Victor P. Kolosov, Olga P. Kurganova, Tatiana A. Zaitseva, Leonid G. Manakov, Galina N. Kholodok, Juliy M. Perelman, Roman S. Kozlov, Natalia M. Ivakhnishina, Olga E. Trotsenko, Albina P. Bondarenko

“…To study the circulation of serovariants of pneumococcus in inflammatory diseases of the respiratory tract and nasopharyngeal carrier, bacteriological and molecular genetic methods (RT-PCR in the mode of multiprime detection) were used. Results. Differences in the frequency and range of serovariants of circulating isolates of pneumococcus in the postvaccinal period and in unvaccinated children, elimination of a number of serotypes, and appearance of circulation of nonvaccinated strains were revealed. …”
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Investigation into the monitoring and control of mechanical dynamics in inclined mining equipment utilizing digital twin technology by Panshi XIE, Hang YANG, Yongping WU, Baofa HUANG, Weidian LIN, Leilei YI

“…This study comprehensively delineates the design framework, structural features, and testing/detection methodologies of a large-scale coal mining face physical simulation system empowered by digital twin technology. …”
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Clinical symptoms of acute appendicitis correlating to its intraoperative anatomical position by Chandan Singh, Aamina Hamdule, Amey Kasbekar, Shishir Kamble

“…Clinical examination showed high sensitivity (100%) but lower specificity (63.64%) for detecting retrocecal appendicitis and lower sensitivity (63.64%) but perfect specificity (100%) for pelvic appendicitis. …”
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Ribosome pausing in amylase producing Bacillus subtilis during long fermentation by Yaozu Han, Biwen Wang, Alberto Agnolin, Gaurav Dugar, Frans van der Kloet, Christopher Sauer, Paul Igor Costea, Max Fabian Felle, Mathis Appelbaum, Leendert W. Hamoen

“…For the highly expressed α-amylase gene amyM several strong ribosome pausing sites were detected, which remained during the long fermentation despite changes in nutrient availability. …”
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A Pool of Bacterium-like Particles Displaying African Swine Fever Virus Antigens Induces Both Humoral and Cellular Immune Responses in Pigs by Jingshan Huang, Hongxia Wu, Tianqi Gao, Huanjie Zhai, Assad Moon, Xin Song, Shuwen Li, Zhanhao Lu, Jing Lan, Dailang Zhong, Xinyu Zhang, Hua-Ji Qiu, Yongfeng Li, Yuan Sun

“…Results: The results showed that the piglets developed detectable serum IgG antibodies 2 weeks after the first immunization, and these high antibody levels were maintained 4 weeks after the booster immunization. …”
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B and NK Cells Closely Correlate with the Condition of Patients with Acute Pancreatitis by Xin Wei, Weifeng Yao, Huiping Li, Jingjing Qian, Yaosheng Xie, Zhuo Zhang, Hong Lu, Liang Shi, Xiangyang Lin

“…Serum concentration of C-reactive protein (CRP), amylase, and lipase and the frequency and absolute number of many types of peripheral lymphocytes (including T, B, NK, CD16+/CD56+ T, CD4+ T, CD8+ T, CD4+CD8+ T, and CD4−CD8− T cells) were detected on admission and the seventh day of standard treatment. …”
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Protective Effects of Necrostatin-1 against Concanavalin A-Induced Acute Hepatic Injury in Mice by Yingqun Zhou, Weiqi Dai, Chunlei Lin, Fan Wang, Lei He, Miao Shen, Ping Chen, Chenfen Wang, Jie Lu, Ling Xu, Xuanfu Xu, Chuanyong Guo

“…The expression of TNF-α, RIP1, and LC3 was detected with immunohistochemical staining. The expression of TNF-α, IFN-γ, IL2, IL6, caspase 3, RIP1, beclin-1, and LC3 protein was assessed by immunofluorescence and western blotting. …”
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Bacterial diversity impacts as a result of combined sewer overflow in a polluted waterway by O. Calderon, H. Porter-Morgan, J. Jacob, W. Elkins

“…At the current study, three sites were sampled one week apart during a dry period and a wet period, where indication of a combined sewage overflow event could be detected. 16s rRNA high-throughput sequencing from these three sites collectively yielded over 1000 species of bacteria belonging to twenty-two classes. …”
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The NT-ProBNP Test in Subjects with End-Stage Renal Disease on Hemodialysis Presenting with Acute Dyspnea: Is Knowing Worth the Cost? by Shaffer R. S. Mok, Jose Avila, Barry Milcarek, Richard Kasama

“…No differences were detected in all other echocardiography measurements. …”
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