Microstructure evolution and recrystallization behavior of two nickel-based single crystal superalloys by XU Fuze, LIN Yongcheng, MA Dexin, HE Daoguang, ZHAO Yunxing, LI Lyu, CHENG Bowen, DENG Yangpi

“…Conversely， no RX was detected in the DD5 SC test plate post-treatment at 1300 ℃. …”
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Effects of endocrine disrupting chemicals, blood metabolome, and epigenetics on breast cancer risk: A multi-dimensional mendelian randomization study by Ningning Song, Xinquan Xi, Kuan Yang, Chongzhe Pei, Lingzhou Zhao

“…These findings not only suggest potential biomarkers for early detection and intervention but also underscore the imperative for further research to rigorously validate these associations.…”
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Determining the effect of frailty on survival in advanced ovarian cancer: study protocol for a prospective multicentre national cohort study (FOLERO) by Daniel Hunde, Niklas Ekerstad, Mihaela Asp, Päivi Kannisto, Madelene Wedin, Charlotte Palmqvist, Pernilla Dahm-Kähler, Yvonne Brandberg, Mirna Abraham-Nordling, Kristina Åhlund, Vilhelm Mörlin, Nina Groes-Kofoed, Sahar Salehi

“…With a fixed sample size of 450 patients, a two-sided α of 0.05 and β of 0.20, the study is powered to detect a difference in 2-year survival of 12.5% by frailty, assuming a 20% prevalence of frailty. …”
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Effects of early neonatal proinflammatory stress on the expression of BDNF transcripts in the brain regions of prepubertal male rats by D. I. Peregud, S. V. Freiman, A. O. Tishkina, L. S. Sokhranyaeva, N. A. Lazareva, M. V. Onufriev, M. Y. Stepanichev, N. V. Gulyaeva

“…BDNF polypeptide concentration was estimated by means of an enzyme-linked immunosorbent assay, while quantitative polymerase chain reaction followed by reverse transcription was used to detect exon-specific BDNF mRNA expression. The levels of BDNF and transcripts, containing common exon IX were similar in the control and LPS-treated rats. …”
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Comprehensive analysis of publications concerning combinations of immunotherapy and targeted therapies for hepatocellular carcinoma: a bibliometric study by Biling Gan, Lei Wu, Shunan Zhou, Zhihong Chen, Fan Wu, Lianqun Xu, Zhenrong Chen, Honghui Ma, Peijia He, Dan Fang, Ning Shi

“…This study provides a bibliometric overview of these therapeutic combinations, evaluating their development and impact.MethodsA rigorous selection process was applied to relevant literature from Web of Science, followed by in-depth bibliometric analyses— including timeline visualization, burst detection, and co-occurrence analysis—using CiteSpace and VOSviewer. …”
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Separation of Inorganic Forms of Tellurium Using On-Site SPE Followed by ICP-MS or ICP-OES—The Right Solution for Water Monitoring by Katarzyna Kińska, Barbara Żelazko, Olga Gajewska, Magdalena Borowska, Monika Sadowska, Beata Krasnodębska-Ostręga

“…The proposed SPE-ICP-MS (inductively coupled plasma mass spectrometry) method allows direct analysis of Te(VI) and Te(IV), with Te(IV) determined after elution from the column. The detection limits obtained for the 5.0 mL sample are 0.02 ng mL⁻¹ and 0.05 ng mL⁻¹ for Te(VI) and Te(IV), respectively. …”
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Intratumoral <i>Fusobacterium nucleatum</i> in Pancreatic Cancer: Current and Future Perspectives by Domenica Lucia D’Antonio, Anna Zenoniani, Samia Umme, Adriano Piattelli, Maria Cristina Curia

“…Furthermore, this review underscores the clinical research significance of <i>Fn</i> as a potential tumor biomarker and therapeutic target, offering a novel outlook on its applicability in cancer detection and prognostic assessment. It is thought that given the role of <i>Fn</i> in tumor formation and metastasis processes via its FadA, FapA, Fap2, and RadD, new therapies for tumor treatment targeting <i>Fn</i> will be developed.…”
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Testing the Purity of <i>Limnospira fusiformis</i> Cultures After Axenicity Treatments by Michael Schagerl, Alexander Kaptejna, Fabian Polz, Sameh S. Ali, Shuhao Huo, Joana Seneca, Petra Pjevac, Vera Hechtl

“…Contamination was also verified by cultivation-independent methods like flow cytometry and 16S rRNA genome amplicon sequencing. We detected taxa of the phyla Proteobacteria, Bacteriodota, Firmicutes and to a lesser extent Verrucomicrobiota. …”
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Design of Conformal Cooling of an Additively Printed Aluminium Die-Casting Mold Component by J. Sviželová, L. Socha, A. Mohamed, M. Pinta, K. Koza, T. Sellner, K. Gryc, M. Dvořák, M. Roh

“…Numerical simulations were validated through the temperature field of the mold detected by a thermal camera during the casting cycle. …”
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Cellulase-Assisted Extraction, Characterization, and Bioactivity against Rheumatoid Arthritis of Astragalus Polysaccharides by Ling Cao, Mi Yu, Chonghui Wang, Yunhui Bao, Minghui Zhang, Ping He, Yan Zhang, Tingting Yang, Lulu Li, Gang Li, Yun Gong

“…This study investigated the effect of cellulase on the isolation of crude Astragalus polysaccharide (APS), analyzed the monosaccharide component of deproteinized APS, detected the molecular weights of purified APS, and examined the biological activities and the preliminary mechanism against rheumatoid arthritis (RA). …”
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Trace elements in children with pre-dialysis and end-stage renal disease by Alsalam Asmaa Abd, Ali Ruaa H., Hussain Haider K., Mahdi Montadher Ali

“…Conclusion: Zn is a promising biomarker for detecting CKD development and distinguishing between CKD stages and ESRD. …”
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Epidemiological Characteristics of Meningococcal Meningitis (2016 to 2018) Four Years after the Introduction of Serogroup A Meningococcal Conjugate Vaccine in Benin by Togbemabou Primous Martial Godjedo, Alidehou Jerrold Agbankpe, Moussiliou Noël Paraiso, Tamegnon Victorien Dougnon, Marie Hidjo, Lamine Baba-Moussa, Honore Bankole

“…These results demonstrated the effectiveness of case-by-case surveillance in detecting small changes in the distribution of serogroups that could have important implications for public health strategies in the coming seasons.…”
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Comparing the diagnosis accuracy and efficacy of presepsin (sCD14) and nCD64 in neonatal sepsis: A systematic review and meta-analysis by Amit Kumar Mittal, Mamta Patel, Dolat Singh Shekhawat, Pratibha Singh, Kuldeep Singh

“…Objective: To evaluate and compare the diagnostic accuracy and clinical utility of sCD14 and nCD64 in detecting neonatal sepsis. Methods: A systematic review and meta-analysis were conducted, including studies that assessed the sensitivity, specificity, and overall diagnostic performance of sCD14 and nCD64. …”
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Isolation and identification of the causal agent of gummy stem blight disease in Cucumis sativus caused by a bacterial pathogen in China by Yidan Wang, Mengjun Jin, Chengde Yang, Fengfeng Cai, Richard Osei, Ting Ma, Cuiwen Zhang, Na Qi

“…Abstract Recently, a new bacterial disease was detected on cucumber stalks. In order to study the pathogenesis of this disease, the pathogenic bacteria were isolated and identified on the basis of morphological and molecular characteristics, and further analyzed for pathogenicity and antagonistic evaluation. …”
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The diagnostic and prognostic value of serum miR-199a-5p combined with echocardiography in acute myocardial infarction by Lixin Xu, Jianfeng Lin, Jianke Xia, Deng Chen, Guohan He

“…RT-qPCR was performed to detect the serum miR-199a-5p level. Pearson analysis was used to analyze the correlation of miR-199a-5p with LVEF and cTnI. …”
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Highly efficient assessment and selective determination of pancreatic cancer biomarker CA-19-9 using co-electrodeposited MXene-AgNPs nanocomposite by Mahsa Mirzayi, Balal Khalilzadeh, Sattar Akbari Nakhjavani, Rahim Mohammad-Rezaei

“…We believe that our fabricated sensor can be the plan of diseases management program due to affordable rapid and label free detection of a targeted biomarkers.…”
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Intraindividual variation in histone acetylation and its impact on autoimmune thyroid diseases by Emi Haga, Naoya Inoue, Yoshinori Iwatani, Yuya Arakawa, Emi Morita, Hidemi Hashimoto, Yusuke Noguchi, Yoh Hidaka, Mikio Watanabe

“…In this study, we analyzed histone H3 acetylation levels in peripheral blood mononuclear cells (PBMCs) using a histone H3 total acetylation detection fast kit. Blood samples were collected before meals, between 8:30–9:00 am, daily for 10 weeks to evaluate the daily variation. …”
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Emergence of invasive Streptococcus dysgalactiae subsp. equisimilis in Spain (2012-2022): genomic insights and clinical correlations by Guillem López de Egea, Aida González-Díaz, Randall J Olsen, Gérard Guédon, Dàmaris Berbel, Immaculada Grau, Jordi Càmara, Lucía Saiz-Escobedo, Sara Calvo-Silveria, Irene Cadenas-Jiménez, José María Marimón, Emilia Cercenado, Antonio Casabella, Sara Martí, M. Ángeles Domínguez, Nathalie Leblond-Bourget, James M Musser, Carmen Ardanuy

“…Methods: We conducted a retrospective, laboratory-based study of iSDSE detected at Hospital Universitari de Bellvitge (HUB) from 2012 to 2022 (n = 89) and isolates collected in three Spanish hospitals in 2018 (n = 22). …”
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Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Vardenafil and Its Application of Bioequivalence by Kok Zheng Gan, Riyanto Teguh Widodo, Zamri Chik, Lay Kek Teh, Mohd Salleh Rofiee, Mohd Izwan Mohamad Yusof

“…The mass transitions m/z 489⟶151 and m/z 390⟶169 were used to measure vardenafil and tadalafil (internal standard), respectively, with a total assay run time of 6 min. The limit of detection was 0.2 ng/mL. The assay was reproducible with intra-assay and interassay precision ranging 1.17%–9.17% and 1.31%–5.86%, respectively. …”
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Emission Characteristics of Volatile Organic Compounds from Typical Coal Utilization Sources: A Case Study in Shanxi of Northern China by Yang Xu, Hualong Yu, Yulong Yan, Lin Peng, Rumei Li, Cheng Wang, Zhiyong Li

“…In this study, we investigated the profiles; benzene, toluene, ethylbenzene, and xylene (BTEX) ratios; ozone formation potential (OFP); and secondary organic aerosol (SOA) formation potential of VOCs generated by coal-utilizing steel plants, power plants, coking plants, and residential stoves in northern China. Among the detected VOCs, the results identified 1-butene as the most abundant species for both the power plants (36.7%) and the residential stoves (41.7%) as well as a significant contributor at the steel plants (7.3%), and alkenes, alkanes, and aromatics composed the largest groups for the power plants (42.0%) and residential stoves (60.2%); steel plants (59.2%); and coking plants (66.1%), respectively. …”
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