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20421
High Expression of UPK3A Promotes the Progression of Gastric Cancer Cells by Inactivating p53 Pathway
Published 2022-01-01“…In addition, the expression of UPK3A, p53, KLF4, ZMAT3, MDM2, and SP1 was detected by qRT-PCR and Western blot assay. Results. …”
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20422
Colon Cancer Genetic and Epigenetic Changes, Etiopathogenesis, Risk Factors, Treatment: Literature Review
Published 2024-06-01“…It highlights the potential of CRISPR/Cas9, immunotherapies, and liquid biopsies in pioneering personalized CRC treatments and early detection. Advances in prevention and technology promise a new era of personalized, effective CRC management strategies. …”
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20423
Escherichia coli O157:H7 Bacteria Antibiotic Resistant Isolated from Flies at Food Courts in IPB Dramaga Campus
Published 2024-12-01“…This study aims to analyze the presence of antibiotic-resistant E. coli O157:H7 bacteria carried by houseflies (M. domestica) in the food court IPB Dramaga campus area. Detection of E. coli O157:H7 on fly legs using qPCR method based on MU 7.2.3.32-8. …”
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20424
Congenital laryngeal anomalies in childhood
Published 2024-10-01“…It should be noted that in all patients, this pathology was detected for the first time when contacting a phoniatrist. …”
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20425
Study of the effect of azithromycin on airway remodeling in asthma via the SAPK/JNK pathway
Published 2024-12-01“…The numbers of inflammatory cells, macrophages, eosinophils, neutrophils and lymphocytes in bronchoalveolar lavage fluid (BALF) were detected by Diff-Quik staining. Inflammatory factor levels (IL-6, TNF-α, IL-4) in BALF, and Collagen I, Collagen III, SAPK/JNK and p-SAPK/JNK protein levels in lung tissues were measured by ELISA and Western blot. …”
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20426
Development and validation of a minimal SNP genotyping panel for the differentiation of Cannabis sativa cultivars
Published 2025-01-01“…However, called genotypes were internally consistent, highlighting discrepancies between genotypes detected using sequencing data and observed using genotyping assays. …”
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20427
CircTRRAP Knockdown Has Cardioprotective Function in Cardiomyocytes via the Signal Regulation of miR-370-3p/PAWR Axis
Published 2022-01-01“…Human cardiomyocyte AC16 was exposed to hypoxia to induce cell injury. Cell viability was detected through Cell Counting Kit-8. CircTRRAP, microRNA-370-3p (miR-370-3p), and Pro-Apoptotic WT1 Regulator (PAWR) levels were assayed by reverse transcription-quantitative polymerase chain reaction. …”
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20428
Evaluating Audience Engagement as a Measure of Digital Diplomacy Effectiveness
Published 2024-09-01“…The analysis of selected metrics reveals two key trends in US digital diplomacy in Russia: since 2022 there has been a notable shift in focus toward Telegram as the primary platform, and while the content partially reaches the existing Russian-speaking audience, it struggles to expand its overall reach.The authors provide six recommendations for diplomatic agencies and consulting firms to enhance the tools for analyzing digital diplomacy engagement: (1) adopt automated engagement metrics that account for the interface differences among social media platforms; (2) incorporate built-in topic modeling of posts; (3) integrate sentiment analysis of comments; (4) develop mechanisms to detect traffic manipulation; (5) track multi-level reposts, the timing and spread of hashtag diplomacy, and audience growth considering these processes; and (6) evaluate digital diplomacy activity concerning responses to comments. …”
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20429
Spread of TEM, VIM, SHV, and CTX-M β-Lactamases in Imipenem-Resistant Gram-Negative Bacilli Isolated from Egyptian Hospitals
Published 2016-01-01“…This study aimed to describe the prevalence of imipenem-resistant Gram-negative bacilli isolates and detection of blaVIM, blaTEM, blaSHV, blaCTX-M-1, and blaCTX-M-9 genes in these clinical isolates in Egyptian hospitals. …”
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20430
A systematic review of the clinical practice guidelines for the assessment, management and treatment of eating disorders during the perinatal period
Published 2025-01-01“…Six overall recommendations were formed from the narrative synthesis of data: 1) Early detection: recognising the signs and symptoms, 2) Assessment and screening: a three-pronged approach, 3) Educating and supporting the mother: the importance of knowledge, 4) Cross-system collaboration, 5) Psychological, pharmacological and medical treatment, and 6) Continued monitoring. …”
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20431
Analysis of Reddit Discussions on Motivational Factors for Physical Activity: Cross-Sectional Study
Published 2025-01-01“…MethodsWe searched for users’ responses regarding PA motives and adherence strategies in Reddit forums dedicated to PA and analyzed the data using (1) unsupervised clustering to identify topics from the textual comments and (2) supervised classification to classify the comments into the detected topics. A panel of experts participated in both steps for annotation and validation purposes. …”
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20432
Precolostral antibody reactivity against Histophilus somni conserved proteins and Escherichia coli whole cells in stillborn and live calves
Published 2025-03-01“…To investigate whether the antibodies were of maternal origin or self-produced, the sera of the dams were evaluated by immunoblotting.In calves, positive reactions to all antigens were detected by ELISA. In ELISA, the greatest variation in the results was observed for IgM class reactivity with selected proteins and the E. coli strain. …”
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20433
Lightweight privacy preservation blockchain framework for healthcare applications using GM-SSO
Published 2025-03-01“…To increase resilience against cyber-attacks and ensure reliability in healthcare data security, Modified Principal Component Analysis (MPCA) enabled anomaly detection models were built using the BoT-IoT dataset. …”
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20434
Open Issues in Statistical Forecasting of Solar Proton Events: A Machine Learning Perspective
Published 2021-10-01“…The best performance is obtained by using the SMOTE algorithm, leading to probability of detection of 0.83 and a FAR of 0.39. Nevertheless, we demonstrate that a relevant FAR on the predictions is a natural consequence of the sample base rates. …”
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20435
Accidental findings of maxillary sinuses in dental patients on CBCT images. A retrospective study
Published 2023-12-01“…CBCT can help in the early detection and evaluation of accidental pathologies within maxillary antra in asymptomatic patients. …”
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20436
Deep learning-based skin lesion analysis using hybrid ResUNet++ and modified AlexNet-Random Forest for enhanced segmentation and classification.
Published 2025-01-01“…Most likely all the patients who received wrong diagnosis and low-quality treatment die early. Though if it is detected in the early stages the patient has fairly good chance and the aforementioned diseases can be cured. …”
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20437
T-Cell Large Granular Lymphocytic Leukemia with Extremely Rare Immunophenotype (CD4/CD8 Double-Positive) Followed by Multiple Myeloma Diagnosis
Published 2020-01-01“…Clonality was further confirmed by PCR with the detection of clonal TCR beta and TCR gamma gene rearrangements. …”
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20438
Clinical effect of digital 3D printed maxillary protraction combined with alternate rapid maxillary expansion and constriction in the treatment of patients with skeletal Class Ⅲ ma...
Published 2025-01-01“…Soft tissue measurements of upper lip distance from the E line improved with a statistically significant difference while no significant changes in nasolabial angle were detected. The volume of the posterior palatal region of the upper airway increased significantly. …”
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20439
The “Triangle” Sign: A Novel Ultrasound Marker for Diagnosing Total Choroidal Detachment and Total Suprachoroidal Hemorrhage
Published 2025-01-01“…Among the 31 eyes with total SCH, 58.3% initially had detectable choroidal membrane seen on B scan, while 41.7% did not. …”
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20440
Serum IL-1β, IL-2, and IL-6 in Insulin-Dependent Diabetic Children
Published 2006-01-01“…In all stages of diabetes higher levels of IL-1β and TNF-α and lower levels of IL-2 and IL-6 were detected. Our data about elevated serum IL-1β, TNF-α and decreased IL-2, IL-6 levels in newly diagnosed IDDM patients in comparison with longer standing cases supports an activation of systemic inflammatory process during early phases of IDDM which may be indicative of an ongoing β-cell destruction. …”
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