The Distribution of Cytotoxic Necrotizing Factors (CNF-1, CNF-2, CNF-3) and Cytolethal Distending Toxins (CDT-1, CDT-2, CDT-3, CDT-4) in Escherichia coli Isolates Isolated from Ext... by Cansu Onlen Guneri, Fatih Koksal, Suna Kizilyildirim, Basak Bedir, Togrul Nagiyev

“…At least one virulence gene was present in 156 (24%) of the 646 ExPEC isolates. We detected cnf1, cnf2, and cnf3, in 78, 12, and 20 ExPEC isolates, respectively. …”
Get full text

Estimating the Relative Risks of Spatial Clusters Using a Predictor–Corrector Method by Majid Bani-Yaghoub, Kamel Rekab, Julia Pluta, Said Tabharit

“…Spatial, temporal, and space–time scan statistics can be used for geographical surveillance, identifying temporal and spatial patterns, and detecting outliers. While statistical cluster analysis is a valuable tool for identifying patterns, optimizing resource allocation, and supporting decision-making, accurately predicting future spatial clusters remains a significant challenge. …”
Get full text

Notch Signaling Pathway Promotes Th17 Cell Differentiation and Participates in Thyroid Autoimmune Injury in Experimental Autoimmune Thyroiditis Mice by Hao Liu, Yiwen Li, Yujiao Zhu, Lei Ma, Haibo Xue

“…HE staining, IHC staining, flow cytometry, RT-qPCR, and ELISA were used to evaluate the degrees of thyroiditis, detect the percentage of Th17 cells and measure the expression of retinoic acid-related orphan receptor gamma t (RORγt), interleukin-17A (IL-17A), and the main components of the Notch signaling pathway. …”
Get full text

The effects of lymphocele formation after living donor kidney transplantation on mid-term allograft function by Christian Kuhn, Bernd Jänigen, Laura Matuschik, Max J. Rieger, Daniel Sidler, Stefan Zschiedrich

“…Results Lymphoceles were detected in 17.4% of the recipients, with a median volume of 129 ml, and 71.8% of these patients required intervention. …”
Get full text

A Case of Severe Cushing Syndrome due to Metastatic Adrenocortical Carcinoma Treated With Osilodrostat by Kathleen R. Ruddiman, DO, Catherine E. Price, MD, ECNU, FACE, Alexander K. Bonnecaze, MD

“…Three months after surgery, hypercortisolemia recurred and bony metastatic disease was detected soon after. The patient received chemotherapy and mitotane; however, mitotane was stopped after development of hemolytic anemia. …”
Get full text

Counteraction corruption under martial law: an analysis of problems and opportunities by O. S. Bondarenko, O. O. Tymoshenko

“…Recommendations aimed at combating corruption in the country have been proposed, among which the key ones are: 1) institutional recommendations providing for the introduction of reform of the Accounting Chamber and the State Audit Service of Ukraine; 2) legal recommendations that provide for the development of effective control mechanisms by public organizations, effective use of assets of corrupt officials and their accomplices for the needs of the state; 3) structural recommendations providing for the formation of specialized departments (and the appointment of responsible persons) with the aim of preventing and detecting corruption and other similar situations.…”
Get full text

Distributions of Ion Density Irregularities and Their Gradients Inside Low‐Latitude Ionospheric Plasma Bubbles Based on C/NOFS Planar Langmuir Probe Data by Emanoel Costa, Patrick A. Roddy, John O. Ballenthin

“…Additionally, the probability density functions (pdfs) of ion density gradients for the EPB West Walls, Centers, and East Walls and the South American longitude sector, detected during 2012 and estimated with different resolutions will be compared. …”
Get full text

Resource selection and survival of plains sharp‐tailed grouse at a wind energy facility by Carly S. Kelly, Chad W. LeBeau, Jeffrey L. Beck, Alex Solem, Hilary Morey, Kurt T. Smith

“…We found consistent selection for lower lengths of transmission lines across all life stages at the home range scale. We did not detect an effect of wind energy infrastructure on nest or female survival. …”
Get full text

Severe anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor encephalitis with prolonged hyperammonemia: a case report by Chunxia Yan, Lingling Bai, Jingwei Du, Zonglei Chong, Guangjun Xu, Xiaoqian Yang

“…Conclusions Even if the short-term prognosis is good, regular tumor-related screening is essential for patients with severe anti-AMPAR-E to detect potential tumors early and improve long-term outcomes. …”
Get full text

The Potential of Swiftlet Bird's Nest Extract (Aerodramus fucipaghus) as an Antioxidant and Serum Formulation by Naniek Widyaningrum, Chintiana Nindya Putri, Thendi Abdul Arief, Nada Aini Sofa, Monica Virdaus

“…Antioxidant activity was detected in the serum across a spectrum of concentrations, revealing IC50 values of 250.00 µg/mL, signifying a range from weak to strong efficacy (90.137 µg/mL). …”
Get full text

Extracellular Vesicles Derived from Adipose Mesenchymal Stem Cells Promote Peritoneal Healing by Activating MAPK-ERK1/2 and PI3K-Akt to Alleviate Postoperative Abdominal Adhesion by Manyu Shi, Hengchen Liu, Tingting Zhang, Mingzhao Zhang, Xin Tang, Zenan Zhang, Wenjun Lu, Shulong Yang, Zhitao Jiang, Qingbo Cui, Zhaozhu Li

“…Expression differences in inflammatory and apoptotic markers were detected using immunofluorescence. The expression of extracellular matrix-related indexes and peritoneal healing were observed using immunohistochemistry. …”
Get full text

Clinical, histopathological and immunohistochemical analysis of vulvar squamous cell carcinoma by Lorenza Bridi Todeschini, Rita de Cássia Sant’Anna Alves, Adriana Vial Roehe

“…Positive p16 and PDL1 staining was detected in 24.4% and 17.1% of the samples, respectively. p53 expression was negative in 19.5% of the samples, whereas it was overexpressed in 24.4%. p16-positive tumors showed a smaller depth of invasion (DOI) (p = 0.014), while tumors with p53 abnormal expression showed greater DOI (p = 0.041). …”
Get full text

Evaluation of the Digital Ventilated Cage® system for circadian phenotyping by Selma Tir, Russell G. Foster, Stuart N. Peirson

“…Our results show the suitability of the DVC system for circadian behavioural screens, accurately detecting circadian period, circadian disruption, phase shifts and mice with clock defects. …”
Get full text

Prevalence of enteroviruses in healthy populations and excretion of pathogens in patients with hand, foot, and mouth disease in a highly endemic area of southwest China. by Qiang Wu, Xiaoqing Fu, Lili Jiang, Rusong Yang, Jianping Cun, Xiaofang Zhou, Yongming Zhou, Yibing Xiang, Wenpeng Gu, Jianhua Fan, Hong Li, Wen Xu

“…Among the healthy subjects, 90 (13.5%) tested positive for viral isolation, but neither EV-A71 nor CV-A16 was detected in healthy individuals. Of the 150 patients with probable HFMD, 55.3% (83/150) tested positive for viral isolation with presented serotypes such as EV-A71 (51.81%, 43/83), CV-A16 (32.53%, 27/83), other EVs (13.25%, 11/83), and mixed EV-A71 and CV-A16 (2.41%, 2/83). …”
Get full text

Humidity Sensor of D-shaped Silver-coated Optical Fiber based on SPR Effect by GUO Xiangyu, ZHANG Zuxing

“…Finally, a layer of GO film is coated on the surface of the D-shaped Ag-coated optical fiber to explore its performance of humidity detection.【Results】The simulation results show that the optimal sensor structure is the polishing depth of 58.4 μm, the thickness of the Ag film is 50 nm, and the maximum wavelength sensitivity of 5 500 nm/RIU is obtained between the ambient RI of 1.34 and 1.40. …”
Get full text

Activating Transcription Factor 5 Promotes Tumorigenic Capability in Cervical Cancer Through the Wnt/β-Catenin Signaling Pathway by Shi F, Wei Y, Huang Y, Yao D

“…This study, aimed to explore the function of ATF5 and its potential mechanisms in cervical cancer.Patients and Methods: Quantitative real-time PCR, Western blot and immunohistochemistry were used to detect the expression of ATF5 in cervical cancer tissues and cell lines. …”
Get full text

Genetics of Inflammatory Bowel Disease: Current Understanding and Future Directions by P. K. Chandra Sekar, R. Veerabathiran

“…These genetic variants, integral to IBD's etiology of IBD, have functional significance because they perturb immune regulation, compromise epithelial barrier integrity, and disrupt mucosal homeostasis, collectively contributing to intestinal inflammation through diverse mechanisms. Early detection of IBD is paramount for arresting disease progression and underscoring the importance of prognostic testing and genetic screening, especially in cases with familial predispositions or very early onset IBD. …”
Get full text

Antibacterial Effect of Fixed and Volatile Oils against Gram-positive and Gram-negative Bacteria by Tara Faiq M. Salih, Sakar Ahmed Abdullah, Salar Ibrahim Ali, Daryan Kamal Khder

“…Bacterial inhibition zone was ?detected by using ?disk diffusion method. Furthermore, volatile oil of N. sativa ?…”
Get full text

Analysis of Foveal and Parafoveal Microvascular Density and Retinal Vessel Caliber Alteration in Inactive Graves’ Ophthalmopathy by Cetin Akpolat, Muhammed M. Kurt, Merve Yılmaz, Fikriye Ordulu, Ferhat Evliyaoglu

“…Optical coherence tomography angiography could be a novel and promising noninvasive diagnostic technique in patients with inactive Graves’ ophthalmopathy to detect foveal and parafoveal vessel density changes compared to healthy subjects. …”
Get full text

Relative Prevalence and Associated Factors of Complex Regional Pain Syndrome Type I in Patients with Radial Head Fractures Treated with Open Reduction and Internal Fixation: A Cros... by Siming Jia, Chuan Ren, Xiaoying Shi, Tailong Shi, Dacheng Sun, Yuqin Zhang, Kai Ding, Hao Du, Yanbin Zhu, Wei Chen

“…The incidence of CRPS I among radial head fracture patients undergoing ORIF was 5.5%. In addition, early detection of CRPS I and providing adequate intervention will likely result in greater benefits for those patients.…”
Get full text