Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi by Mireia Larrosa-Godall, Joshua X. D. Ang, Philip T. Leftwich, Estela Gonzalez, Lewis Shackleford, Katherine Nevard, Rob Noad, Michelle A. E. Anderson, Luke Alphey

“…Gene drives have the potential to spread a desired trait through a population at higher rates than via normal Mendelian inheritance, even in the presence of a fitness cost. …”
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Genetic diversity and antifungal susceptibilities of environmental Cryptococcus neoformans and Cryptococcus gattii species complexes by Mohamed Taha, Yasmine H. Tartor, Rana M Abd Elaziz, Ibrahim Elsohaby

“…Maintaining continued surveillance of the antifungal susceptibility of environmental C. neoformans and C. gattii isolates is desirable for better managing cryptococcosis by identifying resistant isolates and revealing the emergence of intrinsically resistant species. …”
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Formulation and characterization of CMPI nanoparticles for enhanced targeting of brain nicotinic receptors by positive allosteric modulator by Rahma Aly, Shoukath Sulthana, Robert Beaudoin, Ayman K. Hamouda, Santosh Aryal

“…Maximizing delivery of CMPI would enhance its interaction with brain nAChRs that are associated with the desired therapeutic effects while avoiding interactions with peripheral nAChRs that are associated with undesired side effects is critical to the development of nAChR PAM-based therapeutics. …”
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In Silico Identification of New Anti-SARS-CoV-2 Main Protease (Mpro) Molecules with Pharmacokinetic Properties from Natural Sources Using Molecular Dynamics (MD) Simulations and Hi... by Harrison Onyango, Patrick Odhiambo, David Angwenyi, Patrick Okoth

“…Consequently, ZINC000072307130 emerged as the only orally bioavailable drug candidate with desirable pharmacokinetic properties. This candidate drug was used to perform MD simulations, and the outcomes revealed that ZINC000072307130 formed a stable complex with the viral main protease. …”
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Investigating the effects of basil (Ocimum basilicum L.)c mucilage and cellulose nanofiber-based edible films with post-probiotics on fish fillet shelf life by Leila Mokhtaran, Sahar Sabahi, Mohammad Noshad, Seyyed Mohammad Ali Noori

“…The sample featuring basil seed mucilage film, cellulose nanofiber, and 1.5 % postbiotic exhibited exceptional performance in maintaining the desirable qualities of fish fillets throughout the storage period, indicating significant potential for industrial application.…”
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Influence of Drying Methods on the Morphological Features, Microstructural Properties, and Antioxidant Performance of <i>Floccularia luteovirens</i>: A Metabolomic Analysis by Mengjun Xiao, Tao Wang, Chuyu Tang, Min He, Xiaojian Pu, Tingjing Zhao, Yuling Li

“…Our findings indicated that the color of <i>F. luteovirens</i> samples dried using the YG and HG methods was yellow-brown, exhibiting a high degree of browning, whereas the samples processed by the DG method displayed a golden-yellow hue and a desirable fullness. Regarding microstructure, the <i>F. luteovirens</i> samples from the YG and HG methods exhibited small and unevenly distributed pores, in contrast to the samples from the DG method, which were structurally intact and characterized by large inter-tissue pores. …”
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Pengaruh Faktor Emosional Pengguna Terhadap Kesesuaian User Interface pada Sistem Informasi Benih Induk Jeruk di Balitjestro Menggunakan Kansei Engineering by Sobirin Nurfauzi, Akhmad Adi Sulianto, Sandra Malin Sutan, Agus Sugiyatno

“…However, the interface design that is often used tends to be not in accordance with the emotional desires of its users. This study aims to determine the factors that influence the user interface design on the parent citrus seed information system using the Kansei Engineering method to produce a user interface display according to the user's psychological wishes. …”
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Effects of Different Technological Forms of the Perilla frutescens in the Diet on Ruminal Fermentation, Milk and Plasma Fatty Acid Composition, Ruminal Biohydrogenation and Milk Qu... by Selma Büyükkılıç Beyzi, İsmail Ülger, Emrah Kaya, Buğra Ocak, Yusuf Konca

“…ABSTRACT Background Fatty acids can be protected by changing their structure or form against microbial activity, and the different forms of fatty acids can modulate the ruminal biohydrogenation rate and contribute to the desired fatty acid profile in milk fat. Objectives The study investigated the effects of perilla (Perilla frutescens) dietary supplementation in the diet in different technological forms (seed, oil and formaldehyde‐treated oil) on milk, plasma and ruminal fatty acid composition, and milk quality in lactating goats. …”
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Les deux ‘Corinnes’ des Amours d’Ovide by Jacqueline Fabre-Serris

“…Dans cet article, je défends l’hypothèse que ce choix s’explique par le désir d’instaurer une autre compétition entre l’‘ancienne’ Corinne et un poète masculin, lui-même en l’occurrence, et de la gagner en créant une ‘nouvelle’ Corinne. …”
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The combination of hot water spray and subzero saline chilling improved chilling efficiency, meat quality, and sensory attributes by K. Kawamura, D. Ma, D.U. Ahn, H.-S. Seo, V. Hogan, L.N. Stephens, J. Moallem, J.W. Jin, I. Kang

“…Summary: Accelerated poultry processing is always desirable when the product quality, visual appearance, and sensory attributes are the same or better than the conventional processing. …”
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The Ethical Challenges of Gamification in Iran: Uncovering the Dark Side by Mona Jami Pour, Hamideh Binaei

“…It is used as a new approach to reinforce desirable behaviors in employees, increase customer engagement with company products, and even change citizens' perceptions of their environment. …”
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Inorganic nitrogen absorption in the aquaponics farming of sangkuriang catfish (Clarias gariepinus) at uneven retention periods by Zahidah Zahidah, Yuli Andriani, Yayat Dhahiyat, Isni Nurruhwati, Asep Sahidin, Herman Hamdani, Stephanie Marcelia Victoria

“…The 15 minutes retention period gave the most desirable result, with a flow of 0.072 L/s that reduced 58.83% of nitrate, and 33.32% of ammonia has been produced by fish farming activities. …”
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Targeting CXCL8 signaling sensitizes HNSCC to anlotinib by reducing tumor-associated macrophage-derived CLU by Xin Hu, Yikang Ji, Mi Zhang, Zhihui Li, Xinhua Pan, Zhen Zhang, Xu Wang

“…Abstract Background Although nutrition-starvation therapy for malignancies such as HNSCC is highly desirable, the clinical outcomes remain disappointing. …”
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Optimizing Energy and Spectral Efficiency in Mobile Networks: A Comprehensive Energy Sustainability Framework for Network Operators by Luis Mata, Marco Sousa, Pedro Vieira, Maria Paula Queluz, Antonio Rodrigues

“…This framework supports network auditing, benchmarking, monitoring, and energy efficiency optimization while ensuring the desired Quality of Service (QoS). By leveraging Machine Learning (ML) and Explainable Artificial Intelligence (XAI) techniques applied to live data - including Performance Management (PM) and Energy Management (EM) metrics - integrated with domain expertise, the framework goes beyond deterministic computation to identify the root-cause factors influencing the BSs&#x2019; energy class, thereby enabling targeted optimisation. …”
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Resource Management and Health Service Delivery in Rukungiri Municipality: A Case Study of Rwamahwa Health Center IV. by Ndyamuhak,i Faith

“…The study findings on the influence of material resource management on health service delivery at Rwamahwa Health Center IV Rukungiri Municipality were; that the health center has an adequate stock of drugs and medicines which ease service delivery, the health center has all the basic equipment and facilities in place to ensure better service delivery, the health equipments are well maintained to use provision of services and the health centre has a budget for maintenance to ensure that service delivery is to the desired standards. The study findings on the influence of human resource management on health service delivery at Rwamahwa Health Center IV, Rukungiri Municipality were; the health center has all staffing gaps filled which helps to ensure better service delivery, the health center has a medical doctor in place who delivers services promptly, health staff is facilitated to perform their tasks hence better service delivery in the organization, recruitment of health staff is on merit which leads to better provision of services, and deployment of health staff is on merit which leads to better delivery of services. …”
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Investigating the Effect of Increasing Slump on Compressive Strength of Nominal Mix Concrete. by Aturinda, Shallot

“…The study's findings suggest that controlling slump within optimal ranges is crucial to achieving the desired compressive strength in concrete. Additionally, the results highlight the importance of mix ratio selection in conjunction with slump control to ensure optimal concrete performance. …”
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Response surface methodology for the design of malachite green dye removal by γ-Fe2O3 dispersed on reduced graphene oxide sheets by Liu Zhu, Anam Sana, Muhammad Tariq Qamar, Ali Bahadur, Guocong Liu, Mohammad Aslam, Ammar Zidan, İsmail Seçkin Çardaklı, Shahid Iqbal, Sajid Mahmood, Muhammad Saad, Khalid M. Alotaibi

“…The optimal adsorption parameters obtained from the within-range numerical optimization based on 0.923 Derringer’s desirability function were 200 mg/100 mL dose, 80 ppm dye solution, 7.99 pH and 112.68 min. contact time for ~ 90% MG dye removal and 40.64 mg/g adsorption capacity (qm) by rGO/γ-Fe2O3. …”
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Paracrine Proangiogenic Function of Human Bone Marrow-Derived Mesenchymal Stem Cells Is Not Affected by Chronic Kidney Disease by Femke C. C. van Rhijn-Brouwer, Bas W. M. van Balkom, Diana A. Papazova, Diënty H. M. Hazenbrink, Anke J. Meijer, Isaac Brete, Vidalmar Briceno, Arjan D. van Zuilen, Raechel J. Toorop, Joost O. Fledderus, Hendrik Gremmels, Marianne C. Verhaar

“…Administration of allogeneic BM MSCs is less desirable in a patient population likely to require a kidney transplant, but potency of autologous MSCs should be confirmed, given previous indications that CKD-induced dysfunction is present. …”
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Response of alcohol fermentation strains, mixed fermentation and extremozymes interactions on wine flavor by Ling-Zhi Zhao, Ling-Zhi Zhao, Jing Chen, Jing Chen, Jing Chen, Xiang-Ying Wei, Xiang-Ying Wei, Xiang-Ying Wei, Bo Lin, Feng-Jin Zheng, Krishan K. Verma, Gan-Lin Chen, Gan-Lin Chen, Gan-Lin Chen

“…However, the use of mixed fermentation and extremozymes can provide significant insight and potential remedial solutions to overcome these technical problems and shape the final product in more desirable and sustainable ways, challenging the current shortcomings to deliver a more resilient end-products with consistent, flavorful, and a number of what may be considered remedial techniques can be employed to produce an acceptable product to consumers.…”
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Development and validation of soil test crop response model for beetroot (Beta vulgaris) grown in ultisols of India by Ramasamy Arulmani, Ramasamy Arulmani, Kuppayevalasu Malayappagounder Sellamuthu, Kuppayevalasu Malayappagounder Sellamuthu, Subramaniam Maragatham, Subramaniam Maragatham, Alargarsamy Senthil, Alargarsamy Senthil, Seenapuram Palaniswami Thamaraiselvi, Seenapuram Palaniswami Thamaraiselvi, Palaniappan Malathi, Palaniappan Malathi, Govindaraja Sridevi, Govindaraja Sridevi

“…Readily customized of fertilizer nutrient doses was developed for varying soil test values and desired yield targets of beetroot, for both inorganic (NPK) alone and NPK + Farm Yard Manure (FYM). …”
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