Impacts of National Reimbursement Drug Price Negotiation on drug accessibility, utilization, and cost in China: a systematic review by Zheng Zhu, Jiawei Zhang, Zhihu Xu, Quan Wang, Yu Qi, Li Yang

“…One of the following outcomes had to be reported: drug price, availability, affordability, utilization, cost, or health outcomes. The study design had to be a randomized or non-randomized trial, an interrupted time series (ITS) analysis, a repeated measures study, or a controlled before‐after (CBA) study. …”
Get full text

A national study of clinical discussions about cannabis use among Veteran patients prescribed opioids by Tauheed Zaman, Dawn M. Bravata, Amy Byers, Erin Krebs, Samuel Leonard, Charles Austin, Friedhelm Sandbrink, Deborah S. Hasin, Salomeh Keyhani

“…Objective To determine the occurrence of cannabis-related discussions between providers and patients on LTOT during six months following UDT positive for cannabis, and examine factors associated with documenting cannabis use. Design We identified patients prescribed LTOT with a UDT positive for cannabis in 2019. …”
Get full text

Unraveling the subjective well-being of formal and informal caregivers for people with dementia: a comparative analysis by Shanshan Wang, Yuqian Luo, Qiuju Shan, Minhui Liu, Peng Wang, Caihui Huang, Sze Him Isaac Leung

“…To enhance the psychological well-being of informal caregivers, interventions targeting improvements in coping skills and caregiving mastery can be designed; while for formal caregivers, interventions focusing on enhancing caregiving satisfaction and effective coping strategies may be beneficial. …”
Get full text

Allocation and control of multi-devices voltage regulation in distribution systems via rough set theory and grasshopper algorithm: A practical study by Abdullah M. Elsayed, Ali M. El-Rifaie, Marwa F. Areed, Abdullah M. Shaheen, Mohamed Osman Atallah

“…The proposed combined SRST-GOA is designed in a multi-objective framework, focusing on minimizing power loss and cost as well as voltage regulation improvement. …”
Get full text

Effect of a Narrative-Based Online Course Aimed at Reducing Stigma Toward Transgender Children and Adolescents: Longitudinal Observational Study by Merlin Greuel, Van Kinh Nguyen, Doron Amsalem, Maya Adam, Till Bärnighausen

“…Using real voice recordings of transgender children and their caregivers, the videos were designed to elicit empathy and transmit knowledge. …”
Get full text

Cross-sectional Study of EMG and EMG Rise During Fast and Slow Hamstring Exercises by Kasper Krommes, Markus Due Jakobsen, Thomas Bandholm, Lars Louis Andersen, Mette Zebis, Anthony Shield, Per Hölmich, Kristian Thorborg

“… # Purpose This cross-sectional study therefore aimed to compare the Nordic Hamstring curl with a conventional prone Leg Curl at different loads, and novel high velocity Hamstring Catches; in terms of peak normalized electromyographical activity (nEMG) and rate of electromyographic rise (RER) of Biceps Femoris long head, and angular velocity of the knee. # Study design Cross-sectional study. # Methods Out of 28 participants enrolled, the final sample included 23 recreationally active male participants who attended a session for determining RM (repetition maximum) to establish loading (8 and 16RM for Hamstring Catches, and 8, 16 and 24RM for Leg Curl) and to familiarize themselves with the three different exercises (Nordic Hamstring, Leg Curl and Hamstring Catch), and a testing session >4 days after during which EMG data were collected during 3 repetitions of each exercise performed in a random order…”
Get full text

Determining the intention of receiving the influenza vaccine: a cross-sectional survey among international and domestic college students in the USA by Charles Liu, Jiying Ling, ChengChing Liu, Angela Chia-Chen Chen, Nagwan Zahry, Ravichandran Ammigan, Loveleen Kaur

“…This study examined the relationships between the theory of planned behaviour (TPB; attitudes, perceived behavioural control (PBC) and subjective norms) and students’ intention of receiving an influenza vaccine.Design, setting and participants A cross-sectional study was conducted with a convenience sample of 222 domestic students recruited via Amazon Mechanical Turk and 197 international students recruited through the Registrar’s Office at a Midwest university.Results International students had higher levels of PBC, intention and attitudes towards receiving an influenza vaccine compared with domestic students. …”
Get full text

Bacterial interactions underpin worsening lung function in cystic fibrosis-associated infections by Damian W. Rivett, Lauren R. Hatfield, Helen Gavillet, Michelle Hardman, Christopher van der Gast

“…Moreover, it can also be used to support the design and construction of clinically relevant in vitro models of polymicrobial infections.IMPORTANCEResearch studies have repeatedly demonstrated that chronic lung infection in cystic fibrosis is polymicrobial and consequently does not adhere to the single microbe-based Koch’s postulates. …”
Get full text

Eight weeks of aerobic exercise, but not four, improves insulin sensitivity and cardiovascular performance in young women by Maha Sellami, Shamma Almuraikhy, Khaled Naja, Najeha Anwardeen, Hadaia Saleh Al-Amri, Mohammad Shoaib Prince, Amina Ali Aden, Alexander Doemling, Mohamed A. Elrayess

Get full text

Genetic Diversity, Repeat Motifs, and Natural Selection at the C-Terminal Knob-Associated Histidine Rich Protein (KAHRP) of Plasmodium falciparum Clinical Samples from Saudi Arabia by Saad M. Bin Dajem, Md Atique Ahmed, Marie Fe F Bohol, Syeda Wasfeea Wazid, Mohammed I. Shafeai, Fuad H. Rudiny, Ali M. Motaen, Kareem Morsy, Hani Alothaid, Ahmed A. Al-Qahtani

“…Since this is the first study to report on genetic diversity of C-terminal PfKAHRP interaction domain and the repeat motifs from clinical samples in Saudi Arabia, it will contribute towards the rational design of antiadhesion drug therapies for P. falciparum malaria.…”
Get full text

Determinants of Indonesian Government Bond Yield by Hestiani Wulandari, Noer Azam Achsani, Moch. Hadi Santoso

“…Purpose: This research aims to analyze the factors affecting the yield of Indonesian government bonds with maturities of 5, 10, and 30 This research was conducted to identify factors that influence government bond yields using a symmetric approach with the ARDL model. Design/methodology/approach: This research was conducted to identify factors that influence government bond yields using a symmetric approach using the Autoregressive Distributed Lag (ARDL) model. …”
Get full text

Influence of gestational weight gain on baby’s birth weight in Addis Ababa, Central Ethiopia: a follow-up study by Andrew Hayen, Yadeta Dessie, Maralyn Foureur, Fekede Asefa, Allison Cummins

“…However, information regarding the influence of GWG on birth weight is lacking from the Ethiopian setting.Objective This study aimed to determine the influence of GWG and other maternal-related factors on birth weight in Addis Ababa, Ethiopia.Design and methods A cohort of pregnant women who received the first antenatal care before or at 16 weeks of gestation in health centres in Addis Ababa were followed from 10 January 2019 to 25 September 2019. …”
Get full text

Australian children’s foot, ankle and leg problems in primary care: a secondary analysis of the Bettering the Evaluation and Care of Health (BEACH) data by Hylton B Menz, Christopher Harrison, Peter A Lazzarini, Cylie M Williams, Julie Gordon

“…Objectives To explore children’s foot, ankle and leg consultation patterns and management practices in Australian primary care.Design Cross-sectional, retrospective study.Setting Australia Bettering the Evaluation and Care of Health program dataset.Participants Data were extracted for general practitioners (GPs) and patients <18 years from April 2000 to March 2016 inclusive.Main outcome measures Demographic characteristics: sex, GP age groups (ie, <45, 45–54, 55+ years), GP country of training, patient age grouping (0–4, 5–9, 10–14, 15–18 years), postcode, concession card status, indigenous status, up to three patient encounter reasons, up to four encounter problems/diagnoses and the clinical management actioned by the GP.Results Children’s foot, ankle or leg problems were managed at a rate of 2.05 (95% CI 1.99 to 2.11) per 100 encounters during 229 137 GP encounters with children. …”
Get full text

Fuzzy Logic-Based Arrival Time Estimation for Indoor Navigation Using Augmented Reality by Muhammad Hidayat Mohammed Sohif, Muhammad Imran Mardzuki, Azhar Mohd Ibrahim, Ahmad Jazlan

“…Mobile applications designed for indoor navigation often rely on expensive and computationally demanding beacons or natural markers to track the user's location along a predetermined path. …”
Get full text

Gait kinematics at trot before and after repeated ridden exercise tests in young Friesian stallions during a fatiguing 10-week training program by Esther W. Siegers, Jeanne I. M. Parmentier, Jeanne I. M. Parmentier, Marianne M. Sloet van Oldruitenborgh-Oosterbaan, Carolien C. B. M. Munsters, Filipe M. Serra Bragança

“…Earlier, this training program was demonstrated to induce overtraining.ObjectivesTo evaluate how this training program affects stallions’ trot locomotion variables in relation to fatigue.Study designProspective analytical study.Methods3 or 4 years-old (n = 16) Friesian stallions performed three ridden indoor standardized exercise tests (SETs) in week-1 (SET-I; n = 15), week-6 (SET-II; n = 11) and week-10 (SET-III; n = 4), measuring heart rate (bpm) and lactate concentration (LA, mmol/L). …”
Get full text

Age-dependent interaction between serum zinc and triglyceride-glucose index among American adults: National Health and Nutrition Examination Survey by Jun Lai, Jun Lai, Xin-Qing Li, Yinglin Zheng, Zongyan Liu, Qiquan Wu, Yongxiao Cao

“…The association between serum zinc levels and TyG has not yet been explored. Therefore, we designed this cross-sectional study to assess the relationship between serum zinc and TyG in adults using data from the National Health and Nutrition Examination Survey (NHANES).MethodsA cross-sectional analysis was performed on 1,610 adults aged ≥20 years who participated in the National Health and Nutrition Examination Survey (NHANES) 2011–2016. …”
Get full text

Micro-Electro Nanofibrous Dressings Based on PVDF-AgNPs as Wound Healing Materials to Promote Healing in Active Areas by Liu T, Xie F, Geng L, He R, Sun M, Ni T, Xu P, Xing C, Peng Y, Chen K, Fang Y

“…Tiantian Liu,1,2,* Feifei Xie,3,4,* Lele Geng,1,2 Ruizhe He,1,2 Mengzhe Sun,1,2 Tao Ni,1,2 Peng Xu,1,2 Chao Xing,1,2 Yinbo Peng,1,2 Ke Chen,3,4 Yong Fang1,2 1Department of Burns and Plastic Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Institute of Traumatic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 3School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 4Shanghai Key Laboratory of Materials Laser Processing and Modification, Shanghai Jiao Tong University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yong Fang, Department of Burns and Plastic Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China, Email fangyong1020@hotmail.com Ke Chen, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai, People’s Republic of China, Email chenke83@sjtu.edu.cnPurpose: The purpose of this study is to develop an innovative solution for chronic wounds in high-mobility areas, such as joints, where conventional treatments are hindered by passive healing mechanisms and the need for immobilization. By designing a micro-electro-Nanofiber dressing composed of piezoelectric polyvinylidene fluoride (PVDF) integrated with antimicrobial silver nanoparticles (AgNPs), this research aims to address the dual challenges of promoting effective wound healing and maintaining joint mobility.Methods: Herein, we developed a novel micro-electro-Nanofiber dressing using electrospinning technology, incorporating polyvinylidene fluoride (PVDF) with silver nanoparticles (AgNPs). …”
Get full text

Fermentation of Azolla sp. leaves and the utilization as a feed ingredient of tilapia Oreochromis sp. by Nur Bambang Priyo Utomo, Nurfadhilah ., Julie Ekasari

“…The fish used in this study was tilapia Oreochromis sp. with an average weight of 10.59±1.29 g. The design of the feeding treatments was repeletting commercial feed with Azolla leaves by with different supplementation levels, i.e. 0% (A/control), 30% (B), 60% (C), and 90% (D). …”
Get full text

Patient-reported symptoms and admission pathways in stroke mimics versus confirmed stroke or transient ischaemic attack: a cross-sectional observational study by Jawad Haider Butt, Christina Kruuse, Heidi Shil Eddelien, Viktor Frederik Idin Sørensen

“…Objectives To determine patient-reported symptoms and clinical factors associated with mimics and differences in health-seeking behaviour versus stroke.Design This is a post-hoc analysis of a cross-sectional survey of interviews on patient-reported factors in patients admitted with suspected stroke. …”
Get full text

Establishment and characterization of a new mouse gastric carcinoma cell line, MCC by Yushen Wang, Xianju Li, Yi Wang, Jun Qin

“…Results A novel gastric carcinoma cell line, designated MCC, was established from BALB/c mice. This cell line exhibited a doubling time of approximately 33 h. …”
Get full text