Impact of COVID-19 restrictions on behavioural and psychological symptoms in home-dwelling people with dementia: a prospective cohort study (PAN.DEM) by Maarja Vislapuu, Mala Naik, Bettina S Husebø, Marie H Gedde, Ipsit V Vahia, Janne Mannseth, Line I Berge

“…Objectives To investigate the impact of the COVID-19 restrictions on behavioural and psychological symptoms of dementia (BPSD).Design Prospective cohort study (PAN.DEM) nested within the halted parent trial (LIVE@Home.Path).Setting Households in Norway immediate before and 6–9 weeks into the COVID-19 restrictions.Participants 104 dyads (persons with mild to moderate dementia aged ≥65 and their informal carers) completed both prepandemic and pandemic assessments, among 237 in the parent trial. …”
Get full text

DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge by Victoria Gnazzo, Hanaa Saleh, Ítalo A. Castro, Adrianus C. M. Boon, Amelia K. Pinto, James D. Brien, Carolina B. López

“…ABSTRACT A challenge in viral vaccine development is to produce vaccines that generate both neutralizing antibodies to prevent infection and cytotoxic CD8+ T-cells that target conserved viral proteins and can eliminate infected cells to control virus spread. mRNA technology offers an opportunity to design vaccines based on conserved CD8-targeting epitopes, but achieving robust antigen-specific CD8+ T-cells remains a challenge. …”
Get full text

Missed opportunity for nasal continuous positive airway pressure in preterm neonates admitted at a tertiary-level hospital newborn unit in Kenya: a mixed method study by Florence Murila, Peace Kakibibi, Diana Marangu-Boore

“…However, NCPAP is not easily accessible to every preterm neonate in low- and middle-income countries, and this is the case in Kenya.Objectives To determine the proportion of preterm neonates admitted to the newborn unit (NBU) at Kenyatta National Hospital (KNH), a tertiary referral hospital in Kenya, with a missed opportunity for NCPAP and to determine the barriers and facilitators of NCPAP utilisation.Design and setting We conducted a hospital-based cross-sectional study that employed interactive explanatory concurrent mixed methods. …”
Get full text

Servicesheds connect people to the landscapes upon which they depend by Yiyi Zhang, Hugo Thierry, Lara Cornejo, Lael Parrott, Monique Poulin, Kate Sherren, Danika Van Proosdij, Brian Robinson

“…Servicesheds can help planners and managers better design zoning restrictions, restoration activities to benefit communities, or subsidy programmes to replace the value of ES lost due to climate change or land use development. …”
Get full text

Tuberculosis and Sudden Death in Lithuania by Gintarė Zarembaitė, Gabrielė Žiūkaitė, Sigitas Chmieliauskas, Diana Vasiljevaitė, Sigitas Laima, Jurgita Stasiūnienė

“…Materials and methods: This research was designed as a retrospective study focusing on full forensic pathology autopsies between 2015 and 2021. …”
Get full text

Machine learning models predicting risk of revision or secondary knee injury after anterior cruciate ligament reconstruction demonstrate variable discriminatory and accuracy perfor... by Benjamin Blackman, Prushoth Vivekanantha, Rafay Mughal, Ayoosh Pareek, Anthony Bozzo, Kristian Samuelsson, Darren de SA

“…Conclusion Machine learning models designed to predict the risk of revision or secondary knee injury demonstrate variable discriminatory performance when evaluated with AUC or concordance metrics. …”
Get full text

CSGD-YOLO: A Corn Seed Germination Status Detection Model Based on YOLOv8n by Wenbin Sun, Meihan Xu, Kang Xu, Dongquan Chen, Jianhua Wang, Ranbing Yang, Quanquan Chen, Songmei Yang

“…Additionally, during the downsampling process of the backbone network, a downsampling module based on receptive field attention convolution (RFAConv) is designed to boost the model’s focus on areas of interest. …”
Get full text

Development and Evaluation of a Mental Health Chatbot Using ChatGPT 4.0: Mixed Methods User Experience Study With Korean Users by Boyoung Kang, Munpyo Hong

“…CareSam, an advanced cross-lingual chatbot using ChatGPT 4.0 (OpenAI) to provide seamless support in both English and Korean contexts. The chatbot was designed to address the need for more personalized and culturally sensitive mental health support identified in our previous work while providing an accessible and user-friendly interface for Korean young adults. …”
Get full text

Comprehensive investigation into the effects of oxygen concentration on pyrite oxidation processes and key ion migration patterns in black rock layers by Zihang Liu, Zhangjun Dai, Fei Yu, Kaiwen Tong, Jianhua Guo, Kang Huang, Shanglin Qin, Shanxiong Chen

Get full text

Sleep quality and cognitive functioning among Chinese older adults living in the US: a mixed-effects model analysis by Fengyan Tang, Yuyang Zhu, Dasuni Jayawardena, Guoping Jin, Yanping Jiang

“…Methods This observational study utilized a two-wave panel design as part of the PINE, including 2,228 participants aged 65 years or older who self-identified as Chinese. …”
Get full text

Obesity in pregnancy: infant health service utilisation and costs on the NHS by Ronan A Lyons, Ashrafunnesa Khanom, Sinead T Brophy, Kelly L Morgan, Muhammad A Rahman, Rebecca A Hill

“…Objective To estimate the direct healthcare cost of infants born to overweight or obese mothers to the National Health Service in the UK.Design Retrospective prevalence-based study.Setting Combined linked anonymised electronic data sets on a cohort of mother–child pairs enrolled on the Growing Up in Wales: Environments for Healthy Living (EHL) study. …”
Get full text

Healthcare utilization and related costs among older people seeking primary care due to back pain: findings from the BACE-N cohort study by Danielle van der Windt, Milada Cvancarova Småstuen, Kjersti Storheim, Margreth Grotle, Zinajda Zolic-Karlsson, Ørjan Nesse Vigdal, Rikke Munk Killingmo, Lise Kretz

“…Objectives To describe healthcare utilization and estimate associated costs during 1 year of follow-up among older people seeking primary care due to a new episode back pain and to describe healthcare utilization across patients with different risk profiles stratified using the StarT Back Screening Tool (SBST).Design Prospective cohort study.Participants and setting A total of 452 people aged ≥55 years seeking Norwegian primary care with a new episode of back pain were included.Outcome measures The primary outcome of this study was total cost of healthcare utilization aggregated for 1 year of follow-up. …”
Get full text

Understanding and reducing delayed dental care for early childhood caries: a structural equation model approach by Mengmeng Wang, Yu Zhang, Xiaofei Li, Xin Liu

“…This study attempted to analyze the pathways influenced by these factors and provide a theoretical foundation for designing targeted intervention programs. Methods Data were collected from young children who visited the department of stomatology at a tertiary hospital from January to December 2023. …”
Get full text

Domestic sewage irrigation on dynamics of nutrients and heavy metals in soil and wheat (Triticum aestivum L.) production by S. R. Salakinkop, C. S. Hunshal

“…In this context, a field experiment was laid out in splitâsplit plot design with three replications. Main plots constituted two types of lands (fields irrigated with sewage and bore well water since 1992). …”
Get full text

Prevalence of neutropenia in the U.S. among reproductive-aged women: a population-based analysis of NHANES 2013–2020 by Junfeng Chen, Shuangna Song, Yiran Li

“…Methods The present study was designed as a cross-sectional investigation. The data of 5,250 female participants aged 18–45 years were obtained from the National Health and Nutrition Examination Survey (NHANES) conducted between the years 2013 and 2020. …”
Get full text

“If that would have lessened my symptoms, that would have been great...”: a qualitative study about the acceptability of tecovirimat as treatment for mpox by Sara Paparini, Rosalie Hayes, Benjamin Weil, Will Nutland, Ismael Maatouk, Teodora Wi, Chloe M. Orkin, Rosamund Lewis

“…Methods A co-produced, qualitative, focus group study design was conducted with a theoretically informed sample of people from communities at higher risk and with experience of mpox illness. …”
Get full text

Pengembangan Sistem Manajemen Pelatihan Kerja di Kota Surakarta by Affriza Brilyan Relo Pambudi Agus Putra, Shelvie Nidya Neyman, Hendra Rahmawan

“…Information systems are analyzed and designed using the prototyping method, which is part of the process for distributing job training programs in each Service related to utilization. …”
Get full text

Study on Anaerobic Digestion and the Treatment of Livestock and Poultry Waste Liquid by Nanoparticles and Antibiotics in the Context of Carbon Neutrality and Microbial Ecosystems by Xiaofei Zhen, Han Zhan, Ke Li, Ruonan Jiao, Lei Feng, Tie Du

“…Based on the above background, a self-designed system for testing the anaerobic digestion potential of methane was used in this study using chicken manure. …”
Get full text

Turning green: the impact of changing to more eco-friendly respiratory healthcare – a carbon and cost analysis of Dutch prescription data by Evelyn A Brakema, johan Kooistra, Niels Chavannes, Paul Hagedoorn, Pieter ten Have, Peter van Hal, Iris Wichers, Pauline de Heer, Hans C Ossebaard

“…To help mitigate climate change, we assessed the potential emission reduction in CO2 equivalents when replacing pMDIs by non-propellant inhalers (NPIs) in Dutch respiratory healthcare and estimated the associated cost.Design We performed a descriptive analysis of prescription data from two national databases of two independent governmental bodies. …”
Get full text

Practices and knowledge of health personnel about transgenderity in Primary Health Care by Francisco Jean Gomes de Sousa, Edgar Amatuzzi, Andressa Teoli Nunciaroni, Jaime Alonso Caravaca-Morera, Claudia Regina Ribeiro, Adriana Lemos

“…Objective: To describe the practices and knowledge of Nursing Technicians and Community Health Agents of Primary Health Care for the transgender population. Design: Descriptive research with a qualitative approach. …”
Get full text