Effects and utility of an online forward triage tool during the SARS-CoV-2 pandemic: a mixed method study and patient perspectives, Switzerland by Thomas C Sauter, Wolf E Hautz, Martin Müller, Meret E Ricklin, Janet Michel, Annette Mettler, Raphael Stuber, Philipp Jent

“…Objective To assess the effects (quantitatively) and the utility (qualitatively) of a COVID-19 online forward triage tool (OFTT) in a pandemic context.Design A mixed method sequential explanatory study was employed. …”
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Optimization of cross-sectional shape and support parameters of headgate in fully mechanized coal seam with large dip angle and close distance by Kun PAN, Wenjun JU, Junchao WANG, Housheng JIA, Biao HOU, Yinwei WANG, Zhiming ZHANG

“…The research results provide an effective scientific basis for the selection of cross-sectional shapes and the optimization of support designs for similar roadways inthecoal seam with large dip angle and close distance.…”
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Unlocking the genetic potential of Ethiopian fenugreek (Trigonella foenum-graecum L.) genotypes for future breeding by Zebib Berhe, Tesfaye Awas, Asmare Dejen, Metadel Adane, Baye Akele, Musa Adal, Faris Hailu

“…The field experiment was conducted using thirty six fenugreek genotypes (34 accessions and 2 released varieties) with 6x6 simple lattice designs at Wollo University. ANOVA revealed that there was highly significant (p < 0.001) difference among the thirty six genotypes for all studied traits except days to emergence. …”
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Extrapolating empirical measurements of wastewater exfiltration from sanitary sewers to estimate watershed-scale fecal pollution loading in urban stormwater runoff by Joshua A. Steele, Adriana González-Fernández, John F. Griffith, Darcy Ebentier McCargar, Sierra Wallace, Kenneth C. Schiff

“…This is 0.6% of the average daily volume of sewage treated in this sewer collection system and is similar in scale to exfiltration allowed by design standards. Based on ratios of exfiltration loading predictions vs. stormwater loading measurements, the proportion of exfiltrated human fecal load that is estimated to be transported via subsurface pathways (i.e., the subsurface transfer coefficient, STC) to stormwater in the studied catchments is 8.27 × 10−5 (95% CI: 6.30 × 10−5 to 1.37 × 10−4). …”
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Prevalidation of an ELISA for Detection of a New Clinical Entity: Leishmania donovani-Induced Cutaneous Leishmaniasis by Bhagya Deepachandi, Sudath Weerasinghe, Himali Gunathilake, Thisira P. Andrahennadi, Mahendra N. Wickramanayake, Shantha Siri, Vishvanath Chandrasekharan, Preethi Soysa, Yamuna Siriwardana

“…An indirect enzyme-linked immunosorbent assay (ELISA) based on Leishmania promastigote crude antigen (Ag) was designed and optimized in order to utilize in further serological studies on this new clinical entity. …”
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Mesenchymal Stem Cell Therapy for Diabetic Kidney Disease: A Review of the Studies Using Syngeneic, Autologous, Allogeneic, and Xenogeneic Cells by Christian Sávio-Silva, Stephany Beyerstedt, Poliana E. Soinski-Sousa, Expedito B. Casaro, Maria Theresa A. Balby-Rocha, Antônio Simplício-Filho, Jamille Alves-Silva, Érika B. Rangel

“…Future directions include strategies to reduce MSC heterogeneity, standardized protocols for isolation and expansion of those cells, and the development of well-designed large-scale trials to show significant efficacy during a long follow-up, mainly in individuals with DKD.…”
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Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway by Yingfu Chen, Burong Feng, Ye Yuan, Juan Hu, Wei Zhao, Huiwei Jiang, Wen Li, Ziyi Fan, Zhimin Du

“…The purpose of this study is to evaluate the potential roles and mechanisms of AE in hyperlipidemia-induced oxidative stress and inflammation in the heart. Study Design. We established a hyperlipidemia-induced cardiac inflammation model in rats and cells then administered AE and observed its effect on hyperlipidemia-induced cardiac inflammation. …”
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Melatonin induces drought stress tolerance by regulating the physiological mechanisms, antioxidant enzymes, and leaf structural modifications in Rosa centifolia L by Muhammad Ahsan, Adnan Younis, Aftab Jamal, Mohammed O. Alshaharni, Uthman Balgith Algopishi, Abeer Al-Andal, Mateen Sajid, Muhammad Naeem, Jawad Ahmad Khan, Emanuele Radicetti, Mohammad Valipour, Gulzar Akhtar

“…All pots were arranged with a completely randomized design with two-factor factorial setup. Foliar application of melatonin was carried out on the next day of drought treatment and was repeated weekly, while normal watering was regarded as control. …”
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Direct targeting of risk factors significantly increases the detection of liver cirrhosis in primary care: a cross-sectional diagnostic study utilising transient elastography by Guruprasad P Aithal, Indra Neil Guha, Stephen D Ryder, Emilie A Wilkes, David J Harman, Martin W James, Matthew Jelpke, Dominic S Ottey, Timothy R Card

“…Objectives To assess the feasibility of a novel diagnostic algorithm targeting patients with risk factors for chronic liver disease in a community setting.Design Prospective cross-sectional study.Setting Two primary care practices (adult patient population 10 479) in Nottingham, UK.Participants Adult patients (aged 18 years or over) fulfilling one or more selected risk factors for developing chronic liver disease: (1) hazardous alcohol use, (2) type 2 diabetes or (3) persistently elevated alanine aminotransferase (ALT) liver function enzyme with negative serology.Interventions A serial biomarker algorithm, using a simple blood-based marker (aspartate aminotransferase:ALT ratio for hazardous alcohol users, BARD score for other risk groups) and subsequently liver stiffness measurement using transient elastography (TE).Main outcome measures Diagnosis of clinically significant liver disease (defined as liver stiffness ≥8 kPa); definitive diagnosis of liver cirrhosis.Results We identified 920 patients with the defined risk factors of whom 504 patients agreed to undergo investigation. …”
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Early Recognition and Intervention in SIBlingS at High Risk for Neurodevelopment Disorders (ERI-SIBS): a controlled trial of an innovative and ecological intervention for siblings... by Silvia Annunziata, Giulia Purpura, Giulia Purpura, Elena Piazza, Paolo Meriggi, Gabriele Fassina, Laura Santos, Emilia Ambrosini, Antonella Marchetti, Antonella Marchetti, Federico Manzi, Federico Manzi, Davide Massaro, Davide Massaro, Andrea Luna Tacci, Andrea Luna Tacci, Elisabetta Bolognesi, Simone Agostini, Francesca La Rosa, Alessandra Paola Giulia Pedrocchi, Paola Molina, Anna Cavallini

“…This paper presents the protocol of a controlled trial: ERI-SIBS (Early Recognition and Intervention in SIBlingS at High Risk for Neurodevelopment Disorders) is an innovative and ecological early recognition and intervention program designed specifically for siblings of children with ASD.MethodsWe aim to recruit siblings at low risk and high risk of neurodevelopmental disorders. …”
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Optimized extraction and kinetic study of cholesterol oxidase from a newly isolated Escherichia fergusonii strain from local whey samples: insights through a combined experimental... by Simin Khataee, Gholamreza Dehghan, Samaneh Rashtbari, Arezu Marefat, Sina Jamei, Hamed Farzi-Khajeh

“…Finally, an artificial neural network (ANN) was designed to predict the most effective factor in the fermentation process for enzyme production and the purified ChoX activity. …”
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Integrated assessment of carbon dioxide removal portfolios: land, energy, and economic trade-offs for climate policy by Solene Chiquier, Angelo Gurgel, Jennifer Morris, Yen-Heng Henry Chen, Sergey Paltsev

“…We also investigate a CDR portfolio designed to support more scalable and sustainable climate mitigation strategies, and identify trade-offs between reduced economic benefits and lower environmental impacts. …”
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Oncologic oUTcomes of neoadjuvant chemotherapy for obSTructive colon cAncer after steNt decompression (OUTSTAND trial); A study protocol of multicenter non-inferiority randomized c... by Bong-Hyeon Kye, Ji-Hoon Kim, Hyung-Jin Kim, Yoon-Suk Lee, In-Kyu Lee, Won Kyung Kang, Hyeon-Min Cho, Jong-Kyung Park, Chang-Hyeok Ahn, Jae-Im Lee, Seong-Taek Oh, Byung Jo Choi

“…Objectives Patients who undergo successful SEMS placement for obstructive left-sided colon adenocarcinoma without metastases will be eligible for this study. Design This study is a multicenter, non-inferiority, randomized (1:1), open-label, controlled trial. …”
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Dietary intakes, food behaviours, and health indicators among Métis youth in Manitoba, Canada by Chantal Perchotte, Olena Kloss, Joyce Slater, Alan Katz, Bhanu Pilli, Aynslie Hinds, Marcelo L Urquia, Julianne Sanguins, Chris Green, Jaime Cidro, Dan Chateau, Nathan Nickel, Thomas Falkenberg

“…This study, as part of the Food and Nutrition Security for Manitoba Youth (FANS) study, examines dietary intakes, food behaviours, and health indicators of Métis compared to non-Métis youth. Design: This observational cross-sectional study involved a cohort of adolescents completed a self-administered web-based survey on demographics, dietary intake (24-h recall), food behaviours, food security, and select health indicators. …”
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CEMP-1 Levels in Periodontal Wound Fluid during the Early Phase of Healing: Prospective Clinical Trial by Claudia Dellavia, Elena Canciani, Giulio Rasperini, Giorgio Pagni, Matteo Malvezzi, Gaia Pellegrini

“…The aim of the present study was to assess if surgical procedures designed to regenerate periodontium might affect levels of cementum protein-1 (CEMP-1) in periodontal wound fluid during early phase of healing. …”
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Advanced Amperometric Microsensors for the Electrochemical Quantification of Quercetin in <i>Ginkgo biloba</i> Essential Oil from Regenerative Farming Practices by Elena Oancea, Ioana Adina Tula, Gabriela Stanciu, Raluca-Ioana Ștefan-van Staden, Jacobus (Koos) Frederick van Staden, Magdalena Mititelu

“…In response to the growing interest in developing novel plant-based dermo-cosmetic solutions, this study investigates the electrochemical detection of quercetin, a ketone-type flavonoid, extracted from Gingko biloba essential oil. Three newly designed amperometric microsensors were developed to assess their efficacy in detecting quercetin in botanical samples. …”
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Comparative study of cucumber ( Cucumissativus L.) cultivars under organic fertilizer treatments in the Southern Guinea Savanna, Nigeria by A. I. Afe, A.A Olowoake, C.O Akure, M.R Babatunde

“…Method: A 4 x 5 factorial combination of four cucumber cultivars (Poinsett, Marketer, Marketmore, and  Darina hybrid) and four organic fertilizers (Sunshine, Aleshinloye, Gateway, KWASU organic-based fertilizer-KOBF, and the control) in a completely randomized design at the screen house and a randomized complete block in split-plot fashion in the field were replicated three times. …”
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Acceptance and safety of the RSV-preventive treatment of newborns with nirsevimab in the maternity department: a prospective longitudinal cohort study in FranceResearch in context by Charlotte Ocana de Sentuary, Clara Testard, Marion Lagrée, Maxime Leroy, Lisa Gasnier, Alicia Enes-Dias, Constance Leruste, Diariatou Diallo, Michael Génin, Thameur Rakza, François Dubos

“…Summary: Background: To evaluate the acceptance and safety of the treatment of newborns with nirsevimab (a long-acting monoclonal antibody designed to prevent respiratory syncytial virus infections) during the first season of implementation. …”
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Gestational weight gain and increased risk of cesarean delivery across body mass index categoriesAJOG Global Reports at a Glance by Pearl A. McElfish, PhD, Britni L. Ayers, PhD, Nicola L. Hawley, PhD, Aaron Caldwell, PhD, Austin Porter, DrPh, Michael D. Macechko, MD, Donya Watson, MD, Jennifer A. Callaghan-Koru, PhD, James P. Selig, PhD, Jennifer A. Andersen, PhD, Nirvana Manning, MD, Lanita White, PharmD, Enrique Gomez-Pomar, MD, Clare C. Brown, PhD

“…OBJECTIVE: This study aimed to examine if excessive gestational weight gain is associated with increased risk of cesarean delivery across multiple body mass index categories. STUDY DESIGN: Analysis was conducted using vital records data from the National Center for Health Statistics birth records. …”
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The Effects of Employee Relations, Workplace Well-Being, and Compensation on Turnover Intentions: The Mediation Role of Work Stress by Tine Yuliantini, Abdul Rahmat, Eri Marlapa, Fadhila Dhia Malihah, Endri

“…Purpose: This study aims to determine the impact of work relationships, workplace welfare, and compensation on TI mediated by work stress. Design/methodology/approach: PT PICID MM Bogor was used as the research object, and as many as 135 factory employees were respondents. …”
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