How do palliative care doctors recognise imminently dying patients? A judgement analysis by Nicola White, Priscilla Harries, Adam JL Harris, Victoria Vickerstaff, Philip Lodge, Catherine McGowan, Ollie Minton, Christopher Tomlinson, Adrian Tookman, Fiona Reid, Patrick Stone

“…Objectives To identify a group of palliative care doctors who perform well on a prognostic test and to understand how they make their survival predictions.Design Prospective observational study and two cross-sectional online studies.Setting Phase I: an online prognostic test, developed from a prospective observational study of patients referred to palliative care. …”
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Fast perceptual learning induces location-specific facilitation and suppression at early stages of visual cortical processing by Yajie Wang, Zhe Qu, You Wang, Mingze Sun, Mengting Mao, Yulong Ding

“…Here we developed a novel experimental design to investigate the cognitive neural mechanism of location specificity of fast PL. …”
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Use of approved cefazolin based intramammary dry goat treatment and its effects on the milk microbiota by Delower Hossain, Filippo Biscarini, Valentina Monistero, Paola Cremonesi, Bianca Castiglioni, Anoar Jamai Masroure, Alessandro Marinoni, Sara Fusar Poli, Matteo Mezzetti, Maria Filippa Addis, Valerio Bronzo, Erminio Trevisi, Paolo Moroni

“…Therefore, this study was designed to evaluate the effect of an approved cefazolin-based intramammary treatment on the milk microbiota of Alpine dairy goats during the dry and early lactation periods. …”
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Childhood overweight and obesity and back pain risk: a cohort study of 466 997 children by Daniel Prieto-Alhambra, Andrew J Carr, Antony J Palmer, Talita Duarte-Salles, Jose Luis Poveda, Daniel Martinez-Laguna, Carlen Reyes, Jeroen de Bont, Alan Silman

“…Objectives To assess the association between age, sex, socioeconomic group, weight status and back pain risk in a large general population cohort of children.Design and setting A dynamic cohort of children aged 4 years in the Information System for Research in Primary Care (SIDIAP) electronic primary care records data in Catalonia. …”
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TAK-242 improves sepsis-associated acute kidney injury in rats by inhibiting the TLR4/NF-κB signaling pathway by Yan-mei Xia, Yu-qian Guan, Ji-fang Liang, Wei-dong Wu

“…Objective This study was designed to observe the effect of toll-like receptor 4 (TLR4)/nuclear factor kappa-B (NF-κB) pathway activity on sepsis-associated acute kidney injury (SA-AKI), thereby providing new considerations for the prevention and treatment of SA-AKI.Methods The rats were divided into Sham, cecal ligation and puncture (CLP), CLP + vehicle, and CLP + TAK-242 groups. …”
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Taking a partnership approach to embed physical activity in local policy and practice: a Bradford District case study by Jennifer Hall, Elliot Lever, Nathan Dawkins, Emma Young, Jamie Crowther, Rachel Williams, John Pickavance, Sally Barber, Andy Daly-Smith, Anna Chalkley, On behalf of the wider JU:MP team

“…There is a growing body of literature surrounding the design and effectiveness of national policy approaches to physical activity, but evidence related to local-level approaches is lacking. …”
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Anti-sperm Antibody Positivity in Men with Varicocele: A Systematic Review and Meta-Analysis by Marco Falcone, Kadir Bocu, Hakan Keskin, Jesus Fernando Solorzano Vazquez, Ravi Banthia, Tara Mahendran, Muslim Dogan Deger, Vinod Kv, Preto Mirko, Ahmed M. Harraz, Ramadan Saleh, Rupin Shah, Ashok Agarwal

“…A literature search was performed using the Scopus and PubMed databases following the Population Exposure Comparison Outcome, Study Design model. Data extracted from eligible studies were meta-analyzed and expressed as odds ratios (ORs) and confidence intervals (CIs). …”

Prevalence and risk factors associated with prehypertension in Shunde District, southern China by Yuli Huang, Yunzhao Hu, Xiaoyan Cai, Wenke Qiu, Changhua Liu, Dingji Zhu, Jinghai Hua, Yanxian Wu, Dingli Xu

“…Objective To explore the prevalence and combined cardiovascular risk factors of prehypertension in southern China.Design A retrospective study; the logistic regression model was used to find the risk factors of prehypertension.Setting The study was conducted in Shunde District, southern China, using the community-based health check-up information.Participants Participants aged ≥35 years with complete health check-up information data between January 2011 and December 2013 were enrolled and divided into hypertension, prehypertension and optimal blood pressure (BP) groups. …”
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The impact of the coupling relationship between projectile size and yarn dimension on the ballistic performance of plain weave fabric by Kaiying Wang, Xuan Zhou, Wenke Ren, Yiding Wu, Yilei Yu, Yi Zhou, Lizhi Xu, Guangfa Gao

“…The projectile diameter of 12 mm corresponds to the coupling size of 11.159, which provides a size design reference for the macroscopic-based continuum models of aramid plain weave fabrics.…”
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Cranioplasty infection in porous hydroxyapatite: Potential antibacterial properties by Ismail Zaed, Corrado Iaccarino, Francesca Faedo, Laura Grillini, Elisabetta Galassi, Alessandro Dotti, Angelo Nataloni, Francesca Carolina Mannella, Andrea Cardia

“…Method: The test method has been designed to evaluate the potential antimicrobial activity of specimens under dynamic contact conditions to overcome difficulties in ensuring contact of inoculum to the specimen surface. …”
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Factors associated with risk analysis for asymptomatic left ventricular diastolic dysfunction in nondialysis patients with chronic kidney disease by Yajuan Gao, Shengnan Chen, Jiani Fu, Cui Wang, Yali Tang, Yongbai Luo, Xiaozhen Zhuo, Xueying Chen, Yan Shen

“…Therefore, exploring and intervention of the factors associated with risk for LVDD is of great importance in reducing the morbidity and mortality of cardiovascular disease (CVD) complications in CKD patients. We designed this retrospective cross-sectional study to collect clinical and echocardiographic data from 339 nondialysis CKD patients without obvious symptoms of HF to analyze the proportion of asymptomatic left ventricular diastolic dysfunction (ALVDD) and its related factors associated with risk by multivariate logistic regression analysis. …”
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Workload-capacity imbalances and their impact on self-management complexity in patients with multimorbidity: a multicenter cross-sectional study by Binyu Zhao, Yujia Fu, Jingjie Wu, Erxu Xue, Chuyang Lai, Dandan Chen, Qiwei Wu, Jianing Yu, Qiaoyu Wu, Zhihong Ye, Jing Shao

“…In the network analysis, socioeconomic factors exhibited the central nodes (p < 0.05).Conclusions Personalized interventions designed to increase capacity and reduce workload are essential for improving self-management in multimorbid patients. …”
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Evaluation of the implementation in primary care of genetic testing for the screening of MODY2 (iMOgene): protocol for an implementation pilot study by Marie-Ève Poitras, Luigi Bouchard, Samuel Legeay, Vanessa Tremblay-Vaillancourt, Amélie Fournier, Josianne Leblanc, Philippe Caron, Catherine Savard, Nathalie Bettez, Karine Tremblay

“…Thus, to evaluate the implementation in primary care of genetic testing for the screening of MODY2 (iMOgene study), an implementation pilot study has been designed supported by the RE-AIM (Reach, Effectiveness, Adoption, Implementation, Maintenance) framework.Method and analysis Two primary care clinics will be involved in the region of Saguenay-Lac-Saint-Jean (Québec, Canada). …”
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Self-Assembled Peptide Hydrogels PPI45 and PPI47: Novel Drug Candidates for <i>Staphylococcus aureus</i> Infection Treatment by Quanlong Wu, Mengyin Deng, Ruoyu Mao, Na Yang, Ya Hao, Manli Cao, Da Teng, Jianhua Wang

“…In summary, this work lays a valuable cornerstone for the future design and characterization of self-assembling antimicrobial peptides hydrogels to combat <i>S. aureus</i> infection.…”
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Effects of ambient air pollutants on cardiovascular disease hospitalization admission by L. Salvaraji, R. Avoi, M.S. Jeffree, S. Saupin, H.R. Toha, S.B. Shamsudin

“…The additional information obtained from this study will be useful to enhance proper environmental management and reduce air pollution in the cities of Sabah.METHOD: Ecological study design was utilized with cardiovascular disease hospital admission and ambient air pollutants in Sabah retrospective data. …”
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Insights gained through real-time monitoring of porcine reproductive and respiratory syndrome virus and description of temporal trends based on laboratory data in Ontario, Canada by Tatiana Petukhova, Maria Spinato, Tanya Rossi, Michele T. Guerin, Cathy A. Bauman, Pauline Nelson-Smikle, Davor Ojkic, Zvonimir Poljak

“…The final optimized, aggregated, and anonymized datasets were exported to the Tableau server and were used to design dynamic real-time visualizations with Tableau Desktop v.2021.4. …”
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The moderating role of parent–child interaction in the relationship between maltreatment and psychological well-being among preschool children by Cheng Zhang, Chuican Huang, Chunhui Zhang, Weijia Wu, Zhenning Huang, Xue Xia, Sijia Liu, Chen Wang, Qing Luo, Qing Luo, Lichun Fan, Lichun Fan

“…ObjectiveThis study aimed to examine the relationship between maltreatment and psychological well-being among preschool children and explore parent–child interaction’s moderating role on this association.MethodsThis study employed a cross-sectional design and multistage stratified cluster random sampling method. …”
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Barriers and facilitators to facility-based delivery in rural Zambia: a qualitative study of women’s perceptions after implementation of an improved maternity waiting homes interve... by Peter C Rockers, Godfrey Biemba, Davidson H Hamer, Nancy A Scott, Jeanette L Kaiser, Taryn Vian, Rachel M Fong, Thandiwe Ngoma, Jody R Lori, Michelle Munro-Kramer, Misheck Bwalya, Gertrude Musonda, Eden Ahmed Mdluli, Viviane Rutagwera Sakanga, Kayla J Kuhfeldt

“…We qualitatively assessed whether MWHs changed perceived barriers to facility delivery among remote-living women.Design We administered in-depth interviews (IDIs) to a randomly selected subsample of women in intervention (n=78) and control (n=80) groups who participated in the primary quasi-experimental evaluation of an improved MWH model. …”
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Characterising “obesogenic” versus “protective” food consumption, and their value chain among Ghanaian households by Reginald Adjetey Annan, Nana Ama Frimpomaa Agyapong, Robert Aidoo, Charles Apprey, Linda Nana Esi Aduku, Elizabeth C Swart

“… ABSTRACT Objectives: This paper explores the characteristics of Ghanaian households’ consumption of obesogenic versus protective foods, including their retail, distribution, and origin. Design: A household food consumption survey was conducted using an adapted Prospective Urban and Rural Epidemiology study Food Frequency Questionnaire. …”
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Genomic interrogation of invasive group A Streptococcus (iGAS) epidemiology and COVID-19 impacts in Victoria, Australia: a 6-year retrospective studyResearch in context by Jacqueline M. Morris, Jake A. Lacey, Kerrie Stevens, Lamali Sadeesh Kumar, Mathilda Wilmot, Janet Strachan, Marion Easton, Daneeta Hennessy, Tony M. Korman, Andrew J. Daley, Katherine B. Gibney, Adam W.J. Jenney, Steven Y.C. Tong, Benjamin P. Howden, Norelle L. Sherry

“…Phylogenetic analysis identified a previously undescribed emm1 sub-lineage, designated M1Aus, detected in Australia (Victoria and Queensland), Belgium and the United Kingdom. …”
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