Migrant Health Country Profile tool (MHCP-t) for transforming health data collection and surveillance in the Middle East and North African (MENA) region: tool development protocol... by Farah Seedat, Bouchra Assarag, Kolitha Wickramage, Sally Hargreaves, Ana Requena-Mendez, Dominik Zenner, Anna Deal, Stella Evangelidou, Oumnia Bouaddi, Moudrick Abdellatifi, Hassan Edries, Eman Elafef, Taha Maatoug, Anissa Ouahchi, Sara Arias, Adel Abdelkhalek, Ibrahim Ahmed Bani, Kenza Hassouni, Mahmoud Hilali, Mohamed Khalis, Wejdene Mansour, Ali Mtiraoui, Hassan Chrifi, Mohamed Douagi, Abdedayem Khelifi

“…To address this problem, we aim to design and pilot test the Migrant Health Country Profile tool (MHCP-t) which can collate country-level data collection around migration health data, policies and healthcare provision.Methods and analysis The MHCP-t development is a stepwise process that will integrate a process evaluation model with active involvement and engagement of multilevel stakeholders. …”
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Bending performance of SFCBs reinforced UHPC beams prestressed with FRP bars by Wenjie Ge, Feng Zhang, Subedi Sushant, Ashraf Ashour, Kangbao Chen, Shihu Fu, Linfeng Qiu, Laiyong Luo, Dafu Cao

“…This research can provide valuable technical references for the analysis and design of UHPC beams reinforced with SFCBs and prestressed FRP bars.…”
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EV‐Elute: A universal platform for the enrichment of functional surface marker‐defined extracellular vesicle subpopulations by Willemijn S. deVoogt, Rowan Frunt, Raul M. Leandro, Casper S. Triesscheijn, Bella Monica, Ioanna Paspali, Mark Tielemans, Jerney J. J. M. François, Cor W. Seinen, Olivier G. deJong, Sander A. A. Kooijmans

“…However, it has been technically challenging to examine such functional heterogeneity due to a lack of non‐destructive methods to separate EV subpopulations based on their surface markers. Here, we used the Design‐of‐Experiments (DoE) methodology to optimize a protocol, which we name ‘EV‐Elute’, to elute intact EVs from commercially available Protein G‐coated magnetic beads. …”
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Identifying the pedoclimatic conditions most critical in the susceptibility of a grapevine cultivar to esca disease by Valérie Hofstetter, Vinciane Monod, Matthieu Wilhelm, Olivier Viret, Katia Gindro, Daniel Croll, Vivian Zufferey

“…As grapevine cultivars vary widely in their susceptibility to esca, we designed a four-year experiment to identify the environmental factors that influence the expression of the disease in a susceptible cultivar. …”
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Path analysis of factors influencing length of stay and hospitalisation expenses for oral cancer patients in tertiary hospitals in southeastern China: a cross-sectional study by Jing Wang, Chen Chen, Xiaoying Hu, Yi Fan, Yaping Wang, Yu Qiu, Qiujiao Yang, Mingming Xu, Yanfeng Weng, Yanni Li, Lisong Lin, Fa Chen, Baochang He, Fengqiong Liu

“…Aims To investigate the associations between influencing factors with length of stay (LOS) and hospitalisation expenses in oral cancer (OC) patients, and to explore the potential pathways through which these factors influence hospitalisation expenses using path analysis.Design Cross-sectional.Setting A comprehensive tertiary hospital in southeastern China.Participants A total of 810 patients with histologically confirmed primary OC admitted to the First Affiliated Hospital of Fujian Medical University, Fujian Province, between 2015 and 2020.Main outcome measures LOS and hospitalisation expenses for OC patients.Results The median hospitalisation expenses and LOS for OC patients in southeastern China were substantial, amounting to $6330 and 29 days, respectively. …”
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Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases by Wei Wei, Michael Hurwitz, Sabina Signoretti, Lucia Jilaveanu, Toni K Choueiri, David L Rimm, Adebowale Adeniran, Sandra Martínez, Harriet M Kluger, David A Schoenfeld, Myrto Moutafi, Dijana Djureinovic, Ross D Merkin, David A Braun, Fabio Parisi

“…Our findings may have important implications for designing future biomarker and treatment studies and may aid in development of brain metastases-specific therapies.…”
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A state of the art review on geotechnical reinforcement with end life tires by M. Shariati, M. Afrazi, H. Kamyab, S. Rouhanifar, E. Toghroli, M. Safa, Sh. Chelliapan, H. Afrazi

“…Additionally, the article delves into modeling approaches that simulate the intricate behavior of these mixtures, facilitating better design and analysis. The economic feasibility of incorporating scrap tires is investigated, emphasizing the cost-effectiveness achieved through reduced material costs and enhanced infrastructure durability. …”
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Injury characteristics, mechanisms, and game circumstances in junior community-level Australian football by Indianna L. Franke, Andrea B. Mosler, Brooke E. Patterson, Kay M. Crossley, Patrick Clifton, Steven McPhail, Mark J. Scholes, Matthew G. King

“…Objective: Describe the injury characteristics, game circumstances, and immediate action and management of injuries sustained by boys and girls participating in junior community Australian football. Design: Cohort Study. Methods: All community junior Australian football players from one Victorian-based league were eligible to participate if they were injured during a game and presented to the gameday first aid medics. …”
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The effect of Ocimum basilicum on the prevention of postpartum depression symptoms and sleep quality: A triple-blind randomized controlled clinical trial by Monireh Abdi, Elham Rezaei, Mojgan Mirghafourvand, Fatemeh Ebrahimi, Laleh Payahoo, Alireza Shafiei-Kandjani, Solmaz Ghanbari-Homaie

“…Nevertheless, there is no definitive proof confirming their efficacy. This study is designed to assess the effectiveness of basil in preventing postpartum depression (primary outcome) and sleep quality (secondary outcome). …”
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Photoreduction of CO2 to Formic Acid in Aquatic Phase Using Layer Double Hydroxide (LDH) Catalyst by Jenny Rizkiana, Dzaky Auliardi, Aghietyas Choirun Az Zahra, Francesco Thadeo, Wibawa Hendra Saputera, Tatang Hernas Soerawidjaja, Hary Devianto

“…This study provides valuable insight into the material design and demonstrates the potential of Cu-modified Zn-Cr LDH for sustainable CO2 reduction applications. …”
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Impact of the COVID-19 pandemic on utilisation of facility-based essential maternal and child health services from March to August 2020 compared with pre-pandemic March–August 2019... by Grace J Chan, Delayehu Bekele, Bezawit Mesfin Hunegnaw, Kimiko Van Wickle, Chalachew Bekele, Fanos Ashenafi Gebremeskel, Michelle Korte, Christine Tedijanto, Lisanu Taddesse

“…We aimed to assess maternal, newborn and child health (MNCH) service utilisation during the first 6 months of the COVID-19 pandemic compared with prior to the pandemic.Methods We conducted a mixed study design in eight health facilities that are part of the Birhan field site in Amhara, Ethiopia and compared the trend of service utilisation in the first 6 months of COVID-19 with the corresponding time and data points of the preceding year.Result New family planning visits (43.2 to 28.5/month, p=0.014) and sick under 5 child visits (225.0 to 139.8/month, p=0.007) declined over the first 6 months of the pandemic compared with the same period in the preceding year. …”
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Organ-specific immune-related adverse events and prognosis in cancer patients receiving immune checkpoint inhibitors by Xinyue Han, Yingcui Chen, Hong Xie, Yuekai Zhang, Yu Cui, Yaping Guan, Weiwei Nie, Qi Xie, Jisheng Li, Baocheng Wang, Bicheng Zhang, Jun Wang

“…Abstract Background Patients who developed immune-related adverse events (irAEs) could benefit more from treatment with immune checkpoint inhibitors (ICIs) than those who did not develop irAEs. This study was designed to assess whether the occurrence of irAEs or their characteristics are correlated with survival in advanced patients treated with ICIs. …”
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Challenges and barriers to physician decision-making for prescribing and deprescribing among patients with multimorbidity in eastern China’s primary care settings: a qualitative st... by Ming Yan, Zhijie Xu, Andrew Farmer, Yu Xia, Mi Yao, Lingyan Wu, Xinmei Zhou, Liyan Han

“…We aimed to investigate the experiences and perceptions of primary care physicians (PCPs) regarding their decision-making processes in prescribing and deprescribing medications for patients with multimorbidity, and identify the challenges and barriers they face.Design From 5 October 2023 to 27 January 2024, this qualitative study was conducted through semi-structured interviews that encouraged in-depth exploration of the participants’ experiences and perspectives. …”
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European Working Time Directive and doctors’ health: a systematic review of the available epidemiological evidence by Consol Serra, Evangelia Demou, Ewan B Macdonald, Sergio Vargas-Prada, Maria Cruz Rodriguez-Jareño, Kaveh A Sanati, Alenka Škerjanc, Pedro G Reis, Ritva Helimäki-Aro

“…Objective To summarise the available scientific evidence on the health effects of exposure to working beyond the limit number of hours established by the European Working Time Directive (EWTD) on physicians.Design A systematic literature search was conducted in PubMed and EMBASE. …”
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Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

“…Background: Neonicotinoids (NEOs) are well-designed highly selective pesticides that target nicotinic acetylcholine receptors. …”
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A deep learning algorithm to generate synthetic computed tomography images for brain treatments from 0.35 T magnetic resonance imaging by Luca Vellini, Flaviovincenzo Quaranta, Sebastiano Menna, Elisa Pilloni, Francesco Catucci, Jacopo Lenkowicz, Claudio Votta, Michele Aquilano, Andrea D’Aviero, Martina Iezzi, Francesco Preziosi, Alessia Re, Althea Boschetti, Danila Piccari, Antonio Piras, Carmela Di Dio, Alessandro Bombini, Gian Carlo Mattiucci, Davide Cusumano

“…This study introduces a Deep Learning (DL) algorithm designed to quickly generate synthetic CT (sCT) images from low-field MR images in the brain, an area not yet explored. …”
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Characteristics of subacute stroke patients who achieve earlier independence in real-life walking performance during hospitalization by Kenji Kawakami, Shigeo Tanabe, Daiki Kinoshita, Ryo Kitabatake, Hiroo Koshisaki, Kenta Fujimura, Yoshikiyo Kanada, Hiroaki Sakurai

“…Objective: To identify factors associated with earlier independence in “real-life walking” during hospitalization in subacute stroke patients. Design: Retrospective cohort study. Subjects/Patients: Two hundred and six hemiplegic patients. …”
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TOURISM study (Treatment Outcomes in UteRIne SarcoMa): a 10-year retrospective evaluation of practice in the UK by Rebekah Webb, Mohammed Al-Zubaidi, Mark A Baxter, Karin Purshouse, James Robertson, Helen Creedon, Katherine Fair, Asma Sarwar, Laura Hannington, Adam L Peters, Samuel Mcinerney, Karen E Mactier, Georgina E Wood, Mai K Bishr, Leonie Eastlake, Katharine Lankester, Alison L Stillie

“…Treatment options and robust trial data are limited.Objectives The TOURISM study (Treatment Outcomes in UteRIne SarcoMa) is a UK-wide study by the National Oncology Trainees Collaborative for Healthcare Research which aimed to characterise this patient cohort.Design A retrospective descriptive cohort study. Patients with carcinosarcomas/mixed Mullerian tumours, non-uterine gynaecological sarcomas and uterine metastases were excluded. …”
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Overcoming barriers to engagement and adherence to a home-based physical activity intervention for patients with heart failure: a qualitative focus group study by Guy A MacGowan, Sarah Charman, Djordje G Jakovljevic, Nduka C Okwose, Nicola O'Brien, Sophie Cassidy, David Brodie, Kristian Bailey, Leah Avery

“…This study aimed to identify barriers and facilitators to engagement and adherence to a home-based physical activity programme, and to identify ways in which it could be integrated into the care pathway for patients with heart failure.Design A qualitative focus group study was conducted. …”
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Efficacy and Safety of an Aflibercept Treat-and-Extend Regimen in Treatment-Naïve Patients with Macular Oedema Secondary to Central Retinal Vein Occlusion (CRVO): A Prospective 12-... by Jose Garcia-Arumi, Francisco Gómez-Ulla, Navea Amparo, Enrique Cervera, Alex Fonollosa, Luis Arias, Javier Araiz, Juan Donate, Marta Suárez de Figueroa, Lucia Manzanas, Jaume Crespí, Roberto Gallego

“…To evaluate efficacy and safety of an aflibercept treat-and-extend (TAE) regimen in patients with macular oedema (MO) secondary to central retinal vein occlusion (CRVO). Design, Setting, and Patients. Phase IV, prospective, open-label, single-arm trial in 11 Spanish hospitals. …”
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